Mus musculus

443 known processes

Vegfa

vascular endothelial growth factor A

(Aliases: Vegf120,Vpf,Vegf,Vegf164,Vegf188)

Vegfa biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
metanephric glomerular mesangium development GO:0072223 3 1.000
Mouse
blood vessel morphogenesis GO:0048514 285 1.000
urogenital system development GO:0001655 261 1.000
epithelial tube morphogenesis GO:0060562 303 1.000
stem cell differentiation GO:0048863 268 1.000
facial nerve morphogenesis GO:0021610 11 1.000
embryonic organ morphogenesis GO:0048562 276 1.000
heart trabecula formation GO:0060347 14 1.000
positive regulation of glial cell proliferation GO:0060252 4 0.999
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.999
mesenchyme development GO:0060485 152 0.999
retina vasculature development in camera type eye GO:0061298 17 0.999
skeletal system development GO:0001501 356 0.999
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.999
Mouse
renal system vasculature morphogenesis GO:0061438 7 0.999
cell migration involved in coronary angiogenesis GO:0060981 1 0.999
cellular component assembly involved in morphogenesis GO:0010927 139 0.998
mesenchymal cell development GO:0014031 93 0.998
sensory organ morphogenesis GO:0090596 242 0.998
nephron tubule morphogenesis GO:0072078 68 0.998
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.997
response to decreased oxygen levels GO:0036293 59 0.997
Human
respiratory system development GO:0060541 190 0.997
heart morphogenesis GO:0003007 178 0.997
response to hypoxia GO:0001666 58 0.997
Human
clara cell differentiation GO:0060486 4 0.997
cardiac muscle tissue development GO:0048738 130 0.996
ventricular septum morphogenesis GO:0060412 27 0.996
pro t cell differentiation GO:0002572 3 0.996
regulation of apoptotic signaling pathway GO:2001233 197 0.996
mesonephric tubule development GO:0072164 94 0.996
cardiocyte differentiation GO:0035051 87 0.995
glomerular capillary formation GO:0072104 6 0.995
pigment cell differentiation GO:0050931 27 0.995
kidney morphogenesis GO:0060993 83 0.995
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.995
morphogenesis of a branching epithelium GO:0061138 193 0.995
metanephric mesenchymal cell migration GO:0035789 2 0.994
kidney development GO:0001822 213 0.994
blood circulation GO:0008015 195 0.994
renal tubule development GO:0061326 87 0.994
cell migration to the midline involved in heart development GO:0003318 1 0.993
morphogenesis of a branching structure GO:0001763 203 0.993
glomerulus vasculature morphogenesis GO:0072103 6 0.993
retinal blood vessel morphogenesis GO:0061304 3 0.993
mesenchymal cell differentiation GO:0048762 107 0.993
gland development GO:0048732 330 0.993
kidney vasculature development GO:0061440 15 0.992
Mouse
camera type eye development GO:0043010 266 0.991
muscle cell development GO:0055001 133 0.991
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.990
Human
neural crest cell migration GO:0001755 32 0.990
pyramidal neuron migration GO:0021852 1 0.989
embryonic heart tube development GO:0035050 65 0.989
retina development in camera type eye GO:0060041 119 0.989
skeletal muscle organ development GO:0060538 163 0.989
response to growth factor GO:0070848 198 0.988
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.988
cardioblast migration GO:0003260 1 0.988
glomerulus morphogenesis GO:0072102 10 0.988
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.988
myotube differentiation GO:0014902 105 0.988
atrial septum primum morphogenesis GO:0003289 3 0.988
response to oxygen levels GO:0070482 62 0.987
Human
regulation of bmp signaling pathway GO:0030510 60 0.987
stem cell development GO:0048864 219 0.987
kidney vasculature morphogenesis GO:0061439 7 0.986
appendage morphogenesis GO:0035107 149 0.986
connective tissue development GO:0061448 179 0.986
Mouse
muscle adaptation GO:0043500 39 0.986
regulation of vasculogenesis GO:2001212 9 0.986
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.986
positive regulation of ureteric bud formation GO:0072107 3 0.985
digestive tract development GO:0048565 190 0.985
Mouse Fly
neural crest cell differentiation GO:0014033 54 0.985
muscle tissue development GO:0060537 308 0.985
regulation of metanephros development GO:0072215 15 0.985
neural tube formation GO:0001841 108 0.984
positive regulation of bmp signaling pathway GO:0030513 23 0.984
neural crest cell development GO:0014032 48 0.983
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.982
angiogenesis GO:0001525 201 0.982
branching involved in salivary gland morphogenesis GO:0060445 26 0.981
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.980
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.980
Human
muscle cell differentiation GO:0042692 261 0.980
morphogenesis of embryonic epithelium GO:0016331 159 0.979
Mouse
negative regulation of cell proliferation GO:0008285 296 0.979
Mouse
cell type specific apoptotic process GO:0097285 268 0.979
metanephric nephron development GO:0072210 34 0.978
Mouse
nephron tubule development GO:0072080 84 0.977
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.977
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.977
Fly
striated muscle tissue development GO:0014706 293 0.976
mesonephric tubule morphogenesis GO:0072171 63 0.976
cellular response to thyroid hormone stimulus GO:0097067 1 0.976
regulation of cellular ketone metabolic process GO:0010565 66 0.975
embryonic epithelial tube formation GO:0001838 130 0.975
response to peptide hormone GO:0043434 127 0.975
somitogenesis GO:0001756 69 0.974
immune effector process GO:0002252 321 0.974
development of primary sexual characteristics GO:0045137 143 0.974
positive regulation of angiogenesis GO:0045766 46 0.974
regulation of ureteric bud formation GO:0072106 3 0.973
neural tube closure GO:0001843 90 0.972
regulation of skeletal muscle fiber development GO:0048742 36 0.972
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.971
Human
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.971
cell adhesion GO:0007155 329 0.971
response to peptide GO:1901652 136 0.969
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.969
regulation of organ morphogenesis GO:2000027 144 0.968
embryonic viscerocranium morphogenesis GO:0048703 8 0.968
nephron epithelium morphogenesis GO:0072088 68 0.967
megakaryocyte differentiation GO:0030219 26 0.967
regulation of ion transport GO:0043269 215 0.967
pigmentation GO:0043473 71 0.967
g protein coupled receptor signaling pathway GO:0007186 243 0.967
hindbrain development GO:0030902 128 0.966
retina morphogenesis in camera type eye GO:0060042 45 0.966
response to macrophage colony stimulating factor GO:0036005 3 0.965
regulation of smooth muscle cell migration GO:0014910 6 0.964
Mouse
regulation of metal ion transport GO:0010959 106 0.964
cellular response to insulin stimulus GO:0032869 78 0.964
metanephric glomerulus morphogenesis GO:0072275 3 0.964
fused antrum stage GO:0048165 1 0.962
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.962
cellular response to growth factor stimulus GO:0071363 197 0.961
embryonic skeletal system development GO:0048706 120 0.961
cardiac endothelial cell differentiation GO:0003348 4 0.961
developmental pigmentation GO:0048066 40 0.960
stem cell proliferation GO:0072089 117 0.960
embryonic placenta development GO:0001892 98 0.960
Mouse
growth plate cartilage chondrocyte development GO:0003431 3 0.959
molting cycle GO:0042303 90 0.959
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.959
embryonic hemopoiesis GO:0035162 23 0.957
lateral mesodermal cell differentiation GO:0048371 3 0.956
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.956
spermatid differentiation GO:0048515 115 0.956
cardiac myofibril assembly GO:0055003 12 0.955
cellular amine metabolic process GO:0044106 44 0.955
lung alveolus development GO:0048286 45 0.953
Mouse
endothelial cell differentiation GO:0045446 41 0.953
peptidyl amino acid modification GO:0018193 336 0.952
cation homeostasis GO:0055080 212 0.951
tissue remodeling GO:0048771 102 0.950
regulation of striated muscle cell differentiation GO:0051153 81 0.950
coronary vasculature development GO:0060976 12 0.950
endocrine system development GO:0035270 98 0.950
bmp signaling pathway GO:0030509 93 0.948
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.948
cilium morphogenesis GO:0060271 102 0.948
cellular amino acid metabolic process GO:0006520 103 0.947
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.947
regulation of neuron apoptotic process GO:0043523 122 0.946
renal system development GO:0072001 225 0.945
regulation of cardioblast differentiation GO:0051890 3 0.945
metanephric glomerulus vasculature development GO:0072239 7 0.944
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.944
regulation of myoblast differentiation GO:0045661 29 0.944
cardiac muscle cell development GO:0055013 39 0.943
salivary gland morphogenesis GO:0007435 33 0.943
Mouse Fly
hair cycle GO:0042633 90 0.943
Mouse
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.942
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.941
cartilage development GO:0051216 140 0.941
venous blood vessel morphogenesis GO:0048845 7 0.940
cellular response to peptide GO:1901653 92 0.940
ameboidal type cell migration GO:0001667 128 0.940
kidney epithelium development GO:0072073 121 0.937
regulation of cellular amine metabolic process GO:0033238 20 0.937
trachea formation GO:0060440 3 0.936
smooth muscle cell migration GO:0014909 10 0.936
Mouse
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.936
cardiac septum morphogenesis GO:0060411 46 0.935
epithelial tube formation GO:0072175 130 0.934
t cell differentiation GO:0030217 174 0.933
regulation of angiogenesis GO:0045765 81 0.933
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.933
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.932
glomerulus development GO:0032835 40 0.931
Mouse
melanocyte differentiation GO:0030318 25 0.929
wound healing GO:0042060 157 0.928
hypothalamus cell migration GO:0021855 5 0.928
cellular response to acid chemical GO:0071229 68 0.927
cation transport GO:0006812 399 0.926
hematopoietic progenitor cell differentiation GO:0002244 143 0.925
endocardial cushion formation GO:0003272 13 0.925
response to vitamin a GO:0033189 1 0.924
endocardium development GO:0003157 10 0.924
formation of radial glial scaffolds GO:0021943 4 0.923
secondary heart field specification GO:0003139 6 0.923
myelination in peripheral nervous system GO:0022011 19 0.923
ureteric bud morphogenesis GO:0060675 62 0.922
vascular process in circulatory system GO:0003018 62 0.922
apoptotic signaling pathway GO:0097190 306 0.922
trunk neural crest cell migration GO:0036484 4 0.922
branching involved in ureteric bud morphogenesis GO:0001658 56 0.922
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.922
hindbrain tangential cell migration GO:0021934 2 0.921
positive regulation of cardioblast differentiation GO:0051891 3 0.921
renal system vasculature development GO:0061437 15 0.919
Mouse
cell differentiation involved in embryonic placenta development GO:0060706 26 0.919
coronary vasculature morphogenesis GO:0060977 9 0.918
cell migration involved in heart development GO:0060973 8 0.918
response to epidermal growth factor GO:0070849 4 0.917
positive regulation of cellular amine metabolic process GO:0033240 5 0.917
regulation of protein targeting GO:1903533 61 0.915
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.915
anterior commissure morphogenesis GO:0021960 6 0.915
nucleus accumbens development GO:0021768 1 0.915
positive regulation of growth GO:0045927 104 0.915
gliogenesis GO:0042063 141 0.914
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.914
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.913
salivary gland development GO:0007431 37 0.912
Mouse Fly
cell migration involved in kidney development GO:0035787 3 0.911
cardiac muscle cell differentiation GO:0055007 69 0.911
growth plate cartilage development GO:0003417 14 0.911
erythrocyte differentiation GO:0030218 88 0.911
odontogenesis GO:0042476 78 0.910
synaptic transmission GO:0007268 329 0.910
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.910
septum primum development GO:0003284 4 0.909
regulation of mesenchymal cell proliferation GO:0010464 37 0.909
anatomical structure arrangement GO:0048532 20 0.908
vascular endothelial growth factor signaling pathway GO:0038084 10 0.908
cardiac chamber morphogenesis GO:0003206 93 0.908
cardiac chamber development GO:0003205 108 0.906
regionalization GO:0003002 337 0.905
endothelial cell migration GO:0043542 44 0.905
regulation of neuron projection development GO:0010975 169 0.905
embryonic skeletal system morphogenesis GO:0048704 91 0.904
endocardial cell differentiation GO:0060956 4 0.904
erythropoietin mediated signaling pathway GO:0038162 1 0.903
cell proliferation involved in kidney development GO:0072111 14 0.903
Mouse
regulation of transmembrane transport GO:0034762 128 0.903
jak stat cascade GO:0007259 42 0.902
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.902
negative regulation of b cell differentiation GO:0045578 4 0.902
face morphogenesis GO:0060325 29 0.902
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.902
regulation of cellular amino acid metabolic process GO:0006521 5 0.901
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.901
development of primary female sexual characteristics GO:0046545 73 0.900
face development GO:0060324 38 0.900
mitral valve morphogenesis GO:0003183 4 0.900
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.899
positive regulation of cell death GO:0010942 224 0.899
cell migration involved in vasculogenesis GO:0035441 2 0.898
axon guidance GO:0007411 141 0.897
regulation of muscle adaptation GO:0043502 31 0.897
positive regulation of cell migration GO:0030335 109 0.896
Human Mouse
skeletal system morphogenesis GO:0048705 203 0.896
amine metabolic process GO:0009308 45 0.895
cellular response to erythropoietin GO:0036018 1 0.895
positive regulation of endothelial cell migration GO:0010595 12 0.894
Human
metanephric glomerular capillary formation GO:0072277 3 0.894
rhombomere 3 morphogenesis GO:0021658 2 0.893
cellular response to glucocorticoid stimulus GO:0071385 13 0.893
glomerulus vasculature development GO:0072012 14 0.892
Mouse
negative regulation of cell activation GO:0050866 111 0.891
cerebellar granule cell precursor tangential migration GO:0021935 1 0.891
mast cell differentiation GO:0060374 5 0.890
maternal process involved in female pregnancy GO:0060135 32 0.890
regulation of jak stat cascade GO:0046425 34 0.889
regulation of osteoblast differentiation GO:0045667 67 0.889
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.886
Human
mesodermal cell migration GO:0008078 4 0.885
cellular response to decreased oxygen levels GO:0036294 18 0.885
Human
chondrocyte hypertrophy GO:0003415 4 0.885
morphogenesis of a polarized epithelium GO:0001738 37 0.883
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.883
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.882
s shaped body morphogenesis GO:0072050 6 0.882
circulatory system process GO:0003013 197 0.880
regulation of stem cell proliferation GO:0072091 78 0.880
mesonephric epithelium development GO:0072163 94 0.877
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.877
ovulation cycle GO:0042698 59 0.875
cellular response to dna damage stimulus GO:0006974 207 0.875
gonad development GO:0008406 141 0.875
semaphorin plexin signaling pathway GO:0071526 21 0.874
pituitary gland development GO:0021983 38 0.874
atrial cardiac muscle cell differentiation GO:0055011 2 0.873
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.869
regulation of blood vessel remodeling GO:0060312 3 0.868
spermatid development GO:0007286 108 0.867
cellular response to oxygen levels GO:0071453 20 0.864
Human
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.862
cholesterol storage GO:0010878 4 0.862
lateral mesoderm morphogenesis GO:0048369 3 0.862
cellular response to macrophage colony stimulating factor stimulus GO:0036006 3 0.862
alpha amino acid metabolic process GO:1901605 59 0.860
astrocyte activation GO:0048143 2 0.860
blood vessel remodeling GO:0001974 33 0.860
regulation of glomerular mesangial cell proliferation GO:0072124 1 0.860
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.860
Human
regulation of myotube differentiation GO:0010830 62 0.858
lung induction GO:0060492 3 0.856
closure of optic fissure GO:0061386 2 0.855
ventricular cardiac myofibril assembly GO:0055005 3 0.854
phosphatidylinositol mediated signaling GO:0048015 41 0.854
Mouse
positive regulation of nervous system development GO:0051962 221 0.853
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.853
Mouse
ureteric bud development GO:0001657 94 0.852
outflow tract morphogenesis GO:0003151 53 0.850
regulation of smad protein import into nucleus GO:0060390 3 0.846
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 0.846
negative regulation of glial cell proliferation GO:0060253 4 0.846
heart contraction GO:0060047 93 0.845
Mouse
positive regulation of ion transport GO:0043270 65 0.843
negative regulation of cellular amine metabolic process GO:0033239 1 0.842
epithelial cell differentiation involved in kidney development GO:0035850 23 0.841
Mouse
forebrain development GO:0030900 302 0.840
positive regulation of vasculogenesis GO:2001214 7 0.838
ossification GO:0001503 216 0.837
commissural neuron axon guidance GO:0071679 8 0.836
cell substrate adhesion GO:0031589 130 0.836
Human Mouse
branchiomotor neuron axon guidance GO:0021785 7 0.835
determination of heart left right asymmetry GO:0061371 48 0.835
metanephric comma shaped body morphogenesis GO:0072278 1 0.835
response to insulin GO:0032868 100 0.833
negative regulation of epithelial cell proliferation GO:0050680 64 0.833
dendritic cell cytokine production GO:0002371 3 0.831
blood vessel endothelial cell migration GO:0043534 23 0.830
Human
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.829
exogenous drug catabolic process GO:0042738 1 0.828
positive regulation of transcription via serum response element binding GO:0010735 1 0.826
growth plate cartilage chondrocyte growth GO:0003430 2 0.824
positive regulation of dna biosynthetic process GO:2000573 4 0.823
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.822
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.822
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.821
regulation of leukocyte differentiation GO:1902105 159 0.821
neural tube development GO:0021915 160 0.820
lung development GO:0030324 164 0.819
regulation of cellular response to growth factor stimulus GO:0090287 82 0.815
Human Mouse
cell proliferation in hindbrain GO:0021534 10 0.815
hair follicle development GO:0001942 85 0.812
Mouse
lymph vessel morphogenesis GO:0036303 11 0.811
response to organonitrogen compound GO:0010243 246 0.811
positive regulation of apoptotic signaling pathway GO:2001235 95 0.808
male gamete generation GO:0048232 285 0.808
endochondral bone morphogenesis GO:0060350 50 0.808
regulation of endocytic recycling GO:2001135 3 0.808
purine ribonucleotide metabolic process GO:0009150 290 0.807
Human
melanocyte adhesion GO:0097326 1 0.802
renal capsule specification GO:0072130 1 0.802
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.800
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.800
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.800
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.800
labyrinthine layer development GO:0060711 49 0.797
respiratory tube development GO:0030323 167 0.797
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.797
negative regulation of hydrolase activity GO:0051346 71 0.796
Human
inflammatory response GO:0006954 244 0.796
cardiac cell fate determination GO:0060913 2 0.793
regulation of epithelial cell migration GO:0010632 35 0.793
Human
positive regulation of calcium ion transport GO:0051928 27 0.792
negative regulation of neuron apoptotic process GO:0043524 92 0.792
female gonad development GO:0008585 71 0.791
positive regulation of metanephros development GO:0072216 9 0.791
negative regulation of axon extension GO:0030517 19 0.791
nephron epithelium development GO:0072009 92 0.790
positive regulation of kidney development GO:0090184 28 0.790
regulation of cell motility GO:2000145 236 0.789
Human Mouse
positive regulation of adrenergic receptor signaling pathway GO:0071879 3 0.788
regulation of anoikis GO:2000209 2 0.788
sterol homeostasis GO:0055092 45 0.787
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.786
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.784
autonomic nervous system development GO:0048483 43 0.784
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.783
regulation of retinal ganglion cell axon guidance GO:0090259 2 0.782
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 0.781
Human
embryonic heart tube left right pattern formation GO:0060971 5 0.780
actin cytoskeleton organization GO:0030036 220 0.780
Mouse
negative regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000734 1 0.780
muscle system process GO:0003012 141 0.777
Mouse
divalent inorganic cation transport GO:0072511 178 0.776
determination of left right symmetry GO:0007368 80 0.776
regulation of homeostatic process GO:0032844 182 0.775
regulation of intracellular transport GO:0032386 159 0.774
divalent inorganic cation homeostasis GO:0072507 138 0.773
regulation of kidney development GO:0090183 40 0.771
neuroepithelial cell differentiation GO:0060563 37 0.771
neuroblast proliferation GO:0007405 49 0.770
response to erythropoietin GO:0036017 1 0.770
regulation of heart morphogenesis GO:2000826 22 0.766
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.765
positive regulation of leukocyte differentiation GO:1902107 86 0.765
rhythmic process GO:0048511 174 0.764
positive regulation of stem cell proliferation GO:2000648 59 0.763
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.762
regulation of endothelial cell proliferation GO:0001936 23 0.762
glycolipid metabolic process GO:0006664 25 0.761
positive regulation of organelle organization GO:0010638 128 0.761
Human
drug catabolic process GO:0042737 2 0.760
myofibril assembly GO:0030239 34 0.758
regulation of neuron death GO:1901214 134 0.757
head morphogenesis GO:0060323 34 0.755
response to radiation GO:0009314 165 0.753
Fly
regulation of establishment of protein localization GO:0070201 181 0.752
epithelial cell migration GO:0010631 63 0.752
positive regulation of odontogenesis GO:0042482 4 0.748
telencephalon development GO:0021537 186 0.746
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 10 0.746
regulation of calcium ion transport GO:0051924 69 0.746
negative regulation of endothelial cell proliferation GO:0001937 8 0.743
maternal placenta development GO:0001893 20 0.740
hepaticobiliary system development GO:0061008 67 0.740
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.740
bone morphogenesis GO:0060349 78 0.739
reactive oxygen species metabolic process GO:0072593 84 0.738
cellular response to hypoxia GO:0071456 17 0.737
Human
regulation of cardiac cell fate specification GO:2000043 1 0.737
cardiac septum development GO:0003279 59 0.737
cellular response to stem cell factor stimulus GO:0036216 3 0.737
organelle assembly GO:0070925 177 0.736
neuron death GO:0070997 154 0.735
response to vitamin d GO:0033280 3 0.734
nephron morphogenesis GO:0072028 69 0.734
glycerolipid metabolic process GO:0046486 122 0.732
positive regulation of endocytic recycling GO:2001137 2 0.730
mesangial cell differentiation GO:0072007 4 0.730
Mouse
heart field specification GO:0003128 6 0.729
positive regulation of transcription by glucose GO:0046016 3 0.726
central nervous system neuron development GO:0021954 67 0.724
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.723
protein import into nucleus GO:0006606 95 0.721
female sex differentiation GO:0046660 84 0.721
positive regulation of ion transmembrane transport GO:0034767 24 0.719
cell migration involved in metanephros development GO:0035788 2 0.718
developmental programmed cell death GO:0010623 41 0.718
ear morphogenesis GO:0042471 118 0.718
epidermis development GO:0008544 187 0.716
Mouse
striated muscle cell development GO:0055002 125 0.716
endothelial cell apoptotic process GO:0072577 9 0.714
glomerular mesangial cell proliferation GO:0072110 3 0.706
Mouse
vegf activated neuropilin signaling pathway GO:0038190 2 0.705
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.704
regulation of developmental pigmentation GO:0048070 14 0.703
cellular response to corticosteroid stimulus GO:0071384 13 0.703
inositol lipid mediated signaling GO:0048017 41 0.703
Mouse
common partner smad protein phosphorylation GO:0007182 2 0.700
positive regulation of behavior GO:0048520 40 0.700
lung lobe formation GO:0060464 1 0.700
metal ion homeostasis GO:0055065 189 0.700
cell migration involved in endocardial cushion formation GO:0003273 3 0.700
muscle contraction GO:0006936 101 0.698
Mouse
regulation of astrocyte differentiation GO:0048710 20 0.697
regulation of hippo signaling GO:0035330 1 0.693
negative regulation of mesodermal cell fate specification GO:0042662 3 0.692
positive regulation of apoptotic process GO:0043065 217 0.691
cell growth involved in cardiac muscle cell development GO:0061049 3 0.691
establishment of monopolar cell polarity GO:0061162 8 0.691
regulation of hormone secretion GO:0046883 88 0.691
developmental maturation GO:0021700 193 0.686
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.685
placenta development GO:0001890 140 0.685
Mouse
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.684
postganglionic parasympathetic nervous system development GO:0021784 2 0.681
morphogenesis of an epithelial sheet GO:0002011 27 0.678
response to steroid hormone GO:0048545 56 0.678
cardiac right atrium morphogenesis GO:0003213 3 0.678
cellular ketone metabolic process GO:0042180 84 0.677
regulation of lymphocyte differentiation GO:0045619 107 0.677
regulation of membrane potential GO:0042391 192 0.676
brain morphogenesis GO:0048854 32 0.676
metanephric nephron morphogenesis GO:0072273 19 0.676
regulation of organ growth GO:0046620 61 0.675
liver development GO:0001889 66 0.675
positive regulation of lipid storage GO:0010884 10 0.674
cerebellum development GO:0021549 77 0.672
oligodendrocyte differentiation GO:0048709 53 0.672
fat cell differentiation GO:0045444 160 0.671
positive regulation of osteoblast proliferation GO:0033690 9 0.670
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.669
cellular response to lipid GO:0071396 145 0.668
negative regulation of immature t cell proliferation GO:0033087 3 0.668
mitral valve development GO:0003174 4 0.667
response to monosaccharide GO:0034284 67 0.666

Vegfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.996
cardiovascular system disease DOID:1287 0 0.996
disease of cellular proliferation DOID:14566 0 0.921
heart disease DOID:114 0 0.858
myopathy DOID:423 0 0.839
muscular disease DOID:0080000 0 0.839
cardiomyopathy DOID:0050700 0 0.839
intrinsic cardiomyopathy DOID:0060036 0 0.839
musculoskeletal system disease DOID:17 0 0.839
muscle tissue disease DOID:66 0 0.839
cancer DOID:162 0 0.786
integumentary system disease DOID:16 0 0.737