Mus musculus

99 known processes

Wdr77

WD repeat domain 77

(Aliases: p44/MEP50,C79984,2610312E17Rik,2610003I18Rik)

Wdr77 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 84 0.609
nls bearing protein import into nucleus GO:0006607 2 0.557
rna processing GO:0006396 105 0.449
cytoplasmic transport GO:0016482 234 0.359
ribosome biogenesis GO:0042254 20 0.247
macromolecule methylation GO:0043414 120 0.229
methylation GO:0032259 134 0.225
rna splicing GO:0008380 54 0.204
protein complex disassembly GO:0043241 40 0.191
rna splicing via transesterification reactions GO:0000375 43 0.164
nuclear transport GO:0051169 139 0.160
gene silencing by mirna GO:0035195 10 0.147
cellular macromolecule catabolic process GO:0044265 206 0.141
purine nucleotide biosynthetic process GO:0006164 65 0.131
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.129
protein import GO:0017038 101 0.128
mrna splicing via spliceosome GO:0000398 43 0.124
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.106
negative regulation of phosphate metabolic process GO:0045936 184 0.103
establishment of protein localization to organelle GO:0072594 118 0.103
transmembrane transport GO:0055085 412 0.094
nucleolus organization GO:0007000 5 0.092
organonitrogen compound biosynthetic process GO:1901566 192 0.089
signal transduction by p53 class mediator GO:0072331 51 0.080
protein modification by small protein conjugation or removal GO:0070647 207 0.080
nuclear transcribed mrna catabolic process GO:0000956 16 0.079
mrna catabolic process GO:0006402 22 0.078
mitochondrion organization GO:0007005 134 0.078
posttranscriptional regulation of gene expression GO:0010608 155 0.077
protein desumoylation GO:0016926 2 0.076
cellular nitrogen compound catabolic process GO:0044270 280 0.076
rna catabolic process GO:0006401 29 0.073
organophosphate biosynthetic process GO:0090407 122 0.072
nucleocytoplasmic transport GO:0006913 139 0.068
nucleotide biosynthetic process GO:0009165 78 0.066
metaphase plate congression GO:0051310 2 0.065
amine metabolic process GO:0009308 45 0.064
protein targeting GO:0006605 143 0.062
mrna processing GO:0006397 63 0.061
protein alkylation GO:0008213 81 0.059
cellular amine metabolic process GO:0044106 44 0.058
nitrogen compound transport GO:0071705 271 0.051
circulatory system process GO:0003013 197 0.049
macromolecule catabolic process GO:0009057 281 0.048
organic cyclic compound catabolic process GO:1901361 295 0.047
maturation of ssu rrna GO:0030490 1 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.043
nuclear division GO:0000280 158 0.043
regulation of cytoplasmic transport GO:1903649 112 0.042
regulation of organelle organization GO:0033043 289 0.042
protein localization to organelle GO:0033365 185 0.042
ribose phosphate biosynthetic process GO:0046390 59 0.041
negative regulation of dna templated transcription termination GO:0060567 1 0.041
ncrna processing GO:0034470 26 0.040
snorna metabolic process GO:0016074 1 0.039
regulation of intracellular protein transport GO:0033157 82 0.039
peptidyl arginine omega n methylation GO:0035247 2 0.038
regulation of epithelial cell proliferation GO:0050678 141 0.038
dna templated transcription termination GO:0006353 4 0.035
regulation of cell cycle GO:0051726 281 0.034
ribonucleotide biosynthetic process GO:0009260 59 0.034
circadian regulation of gene expression GO:0032922 48 0.032
apoptotic signaling pathway GO:0097190 306 0.032
oocyte anterior posterior axis specification GO:0007314 2 0.031
Fly
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.030
transcription initiation from rna polymerase i promoter GO:0006361 4 0.030
purine ribonucleotide biosynthetic process GO:0009152 59 0.030
mitotic cell cycle GO:0000278 195 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
regulation of cellular response to stress GO:0080135 159 0.029
establishment of rna localization GO:0051236 18 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
protein import into nucleus GO:0006606 95 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
response to inorganic substance GO:0010035 96 0.027
heterocycle catabolic process GO:0046700 280 0.026
intracellular protein transport GO:0006886 204 0.026
rrna processing GO:0006364 10 0.025
ion transmembrane transport GO:0034220 361 0.025
regulation of mrna stability GO:0043488 23 0.025
rna localization GO:0006403 23 0.025
protein localization to nucleus GO:0034504 121 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
regulation of myeloid cell differentiation GO:0045637 96 0.025
ossification GO:0001503 216 0.025
protein modification by small protein conjugation GO:0032446 187 0.024
leukocyte proliferation GO:0070661 172 0.024
negative regulation of protein metabolic process GO:0051248 282 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
nucleoside phosphate biosynthetic process GO:1901293 79 0.023
regulation of translation GO:0006417 71 0.023
protein methylation GO:0006479 81 0.022
aromatic compound catabolic process GO:0019439 286 0.022
negative regulation of protein modification process GO:0031400 163 0.022
regulation of response to dna damage stimulus GO:2001020 34 0.022
organelle fission GO:0048285 170 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.021
regulation of mitotic cell cycle phase transition GO:1901990 73 0.021
spermatogenesis GO:0007283 284 0.021
rna 3 end processing GO:0031123 20 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
response to oxidative stress GO:0006979 123 0.021
organelle disassembly GO:1903008 2 0.021
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.021
positive regulation of protein transport GO:0051222 93 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.020
response to sterol GO:0036314 4 0.020
cation transmembrane transport GO:0098655 266 0.020
myeloid cell differentiation GO:0030099 233 0.020
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.019
regulation of cell cycle process GO:0010564 160 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
maintenance of location GO:0051235 89 0.019
regulation of nucleocytoplasmic transport GO:0046822 73 0.019
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.018
regulation of intracellular transport GO:0032386 159 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
negative regulation of cell cycle GO:0045786 123 0.018
gene silencing by rna GO:0031047 19 0.017
peptidyl amino acid modification GO:0018193 336 0.017
positive regulation of protein localization to nucleus GO:1900182 30 0.017
regulation of body fluid levels GO:0050878 162 0.017
gonad development GO:0008406 141 0.017
male gamete generation GO:0048232 285 0.016
generation of precursor metabolites and energy GO:0006091 103 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
mrna export from nucleus GO:0006406 11 0.015
nuclear export GO:0051168 34 0.015
anatomical structure homeostasis GO:0060249 145 0.015
regulation of protein import into nucleus GO:0042306 52 0.015
regulation of protein localization GO:0032880 231 0.015
blood circulation GO:0008015 195 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
positive regulation of cellular respiration GO:1901857 3 0.014
regulation of protein catabolic process GO:0042176 108 0.014
developmental cell growth GO:0048588 84 0.014
negative regulation of molecular function GO:0044092 258 0.014
meiotic nuclear division GO:0007126 115 0.014
purine containing compound biosynthetic process GO:0072522 70 0.014
defense response to bacterium GO:0042742 119 0.014
lymphocyte proliferation GO:0046651 164 0.013
pyrimidine containing compound metabolic process GO:0072527 11 0.013
epithelial cell proliferation GO:0050673 174 0.013
cellular protein complex disassembly GO:0043624 36 0.013
regulation of protein transport GO:0051223 163 0.013
mitotic cell cycle process GO:1903047 159 0.013
histone h3 k4 trimethylation GO:0080182 5 0.013
positive regulation of gene silencing by mirna GO:2000637 1 0.013
single organism nuclear import GO:1902593 95 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
heart process GO:0003015 94 0.012
body fluid secretion GO:0007589 53 0.012
macromolecular complex disassembly GO:0032984 43 0.012
stem cell differentiation GO:0048863 268 0.012
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
nucleoside monophosphate biosynthetic process GO:0009124 12 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
regulation of rna stability GO:0043487 26 0.011
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
sensory perception GO:0007600 245 0.011
muscle contraction GO:0006936 101 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
negative regulation of cell cycle phase transition GO:1901988 48 0.011
cellular response to lipid GO:0071396 145 0.011
chemotaxis GO:0006935 247 0.011
cation transport GO:0006812 399 0.011
negative regulation of cell development GO:0010721 169 0.010
regulation of dephosphorylation GO:0035303 18 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
regulation of generation of precursor metabolites and energy GO:0043467 38 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
multicellular organismal signaling GO:0035637 91 0.010
establishment of protein localization to membrane GO:0090150 54 0.010
positive regulation of dna templated transcription elongation GO:0032786 2 0.010

Wdr77 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.018
colon cancer DOID:219 0 0.018
gastrointestinal system cancer DOID:3119 0 0.018
intestinal cancer DOID:10155 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
colorectal cancer DOID:9256 0 0.018