Mus musculus

189 known processes

Wwtr1

WW domain containing transcription regulator 1

(Aliases: 2610021I22Rik,Taz,C78399,2310058J06Rik)

Wwtr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hippo signaling GO:0035329 11 0.975
Human Mouse Fly
positive regulation of stem cell maintenance GO:1902459 4 0.975
Mouse
regulation of hippo signaling GO:0035330 1 0.965
actin cytoskeleton organization GO:0030036 220 0.960
positive regulation of glial cell proliferation GO:0060252 4 0.957
Fly
keratinocyte differentiation GO:0030216 48 0.950
Mouse
wnt signaling pathway GO:0016055 188 0.837
kidney development GO:0001822 213 0.824
cilium morphogenesis GO:0060271 102 0.824
regulation of wnt signaling pathway GO:0030111 123 0.787
skin development GO:0043588 220 0.763
Mouse
actin filament organization GO:0007015 113 0.746
regulation of protein serine threonine kinase activity GO:0071900 157 0.734
urogenital system development GO:0001655 261 0.719
cell adhesion GO:0007155 329 0.717
positive regulation of protein kinase activity GO:0045860 144 0.707
cell differentiation involved in metanephros development GO:0072202 12 0.705
cell junction assembly GO:0034329 52 0.705
glomerulus development GO:0032835 40 0.705
ameboidal type cell migration GO:0001667 128 0.701
Fly
regulation of cell motility GO:2000145 236 0.693
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.689
single organism cell adhesion GO:0098602 156 0.683
canonical wnt signaling pathway GO:0060070 130 0.634
cell substrate adhesion GO:0031589 130 0.631
epithelial cell differentiation involved in kidney development GO:0035850 23 0.620
cell matrix adhesion GO:0007160 68 0.617
cell cell junction organization GO:0045216 72 0.602
heart morphogenesis GO:0003007 178 0.588
Mouse
response to retinoic acid GO:0032526 56 0.572
Mouse
cellular lipid metabolic process GO:0044255 323 0.571
metanephric epithelium development GO:0072207 21 0.563
blood vessel morphogenesis GO:0048514 285 0.556
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.555
nephron development GO:0072006 109 0.555
epidermis development GO:0008544 187 0.536
Mouse
positive regulation of kinase activity GO:0033674 155 0.501
cellular response to lipid GO:0071396 145 0.500
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.493
muscle tissue development GO:0060537 308 0.492
regulation of cell migration GO:0030334 219 0.491
cellular response to gamma radiation GO:0071480 4 0.481
metanephric tubule development GO:0072170 18 0.473
positive regulation of stem cell differentiation GO:2000738 23 0.469
Human Mouse
epithelium migration GO:0090132 63 0.467
Fly
muscle system process GO:0003012 141 0.462
cell junction organization GO:0034330 77 0.458
metanephric nephron tubule development GO:0072234 16 0.443
stem cell development GO:0048864 219 0.415
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.408
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.407
primary neural tube formation GO:0014020 95 0.403
renal system development GO:0072001 225 0.401
ossification GO:0001503 216 0.396
cell fate specification GO:0001708 72 0.389
Fly
embryonic organ morphogenesis GO:0048562 276 0.380
Mouse
response to acid chemical GO:0001101 111 0.377
Mouse
muscle cell differentiation GO:0042692 261 0.376
ribonucleotide metabolic process GO:0009259 291 0.373
regulation of system process GO:0044057 200 0.371
cation transport GO:0006812 399 0.362
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.349
Mouse
mesenchyme development GO:0060485 152 0.349
cellular response to dna damage stimulus GO:0006974 207 0.346
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.344
Mouse
camera type eye development GO:0043010 266 0.344
regulation of transferase activity GO:0051338 263 0.338
Human
regulation of nucleotide metabolic process GO:0006140 169 0.336
regulation of cell adhesion GO:0030155 154 0.334
notochord development GO:0030903 20 0.332
Mouse
positive regulation of cell migration GO:0030335 109 0.327
establishment or maintenance of cell polarity GO:0007163 86 0.322
embryonic heart tube morphogenesis GO:0003143 51 0.316
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.311
nucleotide metabolic process GO:0009117 332 0.308
positive regulation of cell motility GO:2000147 116 0.304
glycosyl compound catabolic process GO:1901658 206 0.304
respiratory tube development GO:0030323 167 0.298
regulation of actin filament based process GO:0032970 99 0.297
retinal blood vessel morphogenesis GO:0061304 3 0.295
skeletal system development GO:0001501 356 0.294
cellular macromolecule catabolic process GO:0044265 206 0.292
angiogenesis GO:0001525 201 0.288
embryonic heart tube development GO:0035050 65 0.287
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.285
fat cell differentiation GO:0045444 160 0.284
regulation of epithelial cell proliferation GO:0050678 141 0.283
Mouse
regulation of angiogenesis GO:0045765 81 0.282
regulation of cell projection organization GO:0031344 206 0.275
epithelial tube formation GO:0072175 130 0.272
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.265
Human
sensory organ morphogenesis GO:0090596 242 0.265
muscle adaptation GO:0043500 39 0.264
lung development GO:0030324 164 0.264
small gtpase mediated signal transduction GO:0007264 97 0.263
cellular response to acid chemical GO:0071229 68 0.263
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.262
cell differentiation involved in kidney development GO:0061005 33 0.261
regulation of cellular component biogenesis GO:0044087 181 0.260
adherens junction organization GO:0034332 28 0.255
regulation of peptidase activity GO:0052547 96 0.254
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.251
regulation of stem cell maintenance GO:2000036 17 0.251
Mouse
regulation of protein kinase activity GO:0045859 232 0.246
Human
lamellipodium organization GO:0097581 29 0.246
cellular ketone metabolic process GO:0042180 84 0.245
single organismal cell cell adhesion GO:0016337 131 0.244
kidney morphogenesis GO:0060993 83 0.241
actin filament bundle assembly GO:0051017 40 0.235
wound healing GO:0042060 157 0.231
positive regulation of cellular component biogenesis GO:0044089 94 0.228
lipid biosynthetic process GO:0008610 179 0.227
negative regulation of stem cell differentiation GO:2000737 14 0.226
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.225
Human
morphogenesis of a polarized epithelium GO:0001738 37 0.224
ribonucleoside catabolic process GO:0042454 206 0.223
ribonucleoside triphosphate metabolic process GO:0009199 220 0.223
nephron tubule epithelial cell differentiation GO:0072160 11 0.220
regulation of stem cell proliferation GO:0072091 78 0.220
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.219
mesenchymal cell differentiation GO:0048762 107 0.218
digestive tract development GO:0048565 190 0.217
coagulation GO:0050817 78 0.215
regulation of neuron differentiation GO:0045664 281 0.213
positive regulation of transferase activity GO:0051347 167 0.210
endothelial cell migration GO:0043542 44 0.209
regulation of cellular amine metabolic process GO:0033238 20 0.208
gtp metabolic process GO:0046039 144 0.205
positive regulation of gliogenesis GO:0014015 27 0.205
Fly
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.205
purine nucleotide catabolic process GO:0006195 211 0.204
stem cell differentiation GO:0048863 268 0.202
i kappab kinase nf kappab signaling GO:0007249 85 0.196
nucleoside catabolic process GO:0009164 206 0.196
tube formation GO:0035148 140 0.194
amine metabolic process GO:0009308 45 0.194
positive regulation of cell death GO:0010942 224 0.191
branching involved in salivary gland morphogenesis GO:0060445 26 0.190
morphogenesis of an epithelial sheet GO:0002011 27 0.188
Fly
contact inhibition GO:0060242 3 0.186
epithelial tube morphogenesis GO:0060562 303 0.184
Mouse
cell fate commitment GO:0045165 210 0.184
Fly
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.177
regulation of gliogenesis GO:0014013 50 0.176
Fly
cardiocyte differentiation GO:0035051 87 0.176
purine nucleotide metabolic process GO:0006163 302 0.176
regulation of cellular component size GO:0032535 121 0.175
regulation of cell projection assembly GO:0060491 38 0.175
regulation of actin cytoskeleton organization GO:0032956 84 0.174
negative regulation of phosphorus metabolic process GO:0010563 184 0.170
Human
positive regulation of wnt signaling pathway GO:0030177 45 0.168
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.168
extrinsic apoptotic signaling pathway GO:0097191 126 0.166
Mouse
stem cell proliferation GO:0072089 117 0.165
Mouse Fly
striated muscle tissue development GO:0014706 293 0.165
neural tube formation GO:0001841 108 0.164
purine containing compound metabolic process GO:0072521 311 0.164
regulation of purine nucleotide metabolic process GO:1900542 169 0.162
regulation of blood vessel endothelial cell migration GO:0043535 12 0.161
myelination in peripheral nervous system GO:0022011 19 0.161
stem cell maintenance GO:0019827 130 0.160
Mouse
connective tissue development GO:0061448 179 0.158
metanephric nephron tubule epithelial cell differentiation GO:0072257 5 0.158
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.157
negative regulation of fat cell differentiation GO:0045599 36 0.157
skeletal muscle organ development GO:0060538 163 0.156
regulation of endopeptidase activity GO:0052548 89 0.155
organophosphate catabolic process GO:0046434 232 0.152
blood circulation GO:0008015 195 0.151
negative regulation of molecular function GO:0044092 258 0.149
Human
regulation of stem cell differentiation GO:2000736 50 0.149
Human Mouse
regulation of ossification GO:0030278 112 0.146
substrate adhesion dependent cell spreading GO:0034446 30 0.146
actin polymerization or depolymerization GO:0008154 54 0.145
regulation of muscle system process GO:0090257 80 0.144
cellular amine metabolic process GO:0044106 44 0.144
regulation of cell cycle GO:0051726 281 0.144
protein import into nucleus GO:0006606 95 0.143
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.143
retina development in camera type eye GO:0060041 119 0.143
leukocyte differentiation GO:0002521 342 0.142
telencephalon development GO:0021537 186 0.141
transmission of nerve impulse GO:0019226 76 0.141
multicellular organismal homeostasis GO:0048871 164 0.141
positive regulation of cell development GO:0010720 237 0.141
Human Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.139
hemostasis GO:0007599 78 0.139
synaptic transmission GO:0007268 329 0.138
epiboly GO:0090504 8 0.138
regulation of actin filament length GO:0030832 45 0.138
morphogenesis of a branching structure GO:0001763 203 0.137
nucleoside triphosphate catabolic process GO:0009143 205 0.136
response to radiation GO:0009314 165 0.136
neuronal action potential GO:0019228 54 0.135
axonogenesis GO:0007409 274 0.134
neural tube closure GO:0001843 90 0.134
positive regulation of growth GO:0045927 104 0.132
Mouse Fly
cellular response to growth factor stimulus GO:0071363 197 0.131
integrin mediated signaling pathway GO:0007229 27 0.128
nucleobase containing small molecule metabolic process GO:0055086 352 0.127
organonitrogen compound catabolic process GO:1901565 264 0.126
phospholipid metabolic process GO:0006644 87 0.123
cartilage development GO:0051216 140 0.121
extracellular matrix organization GO:0030198 147 0.121
positive regulation of smooth muscle cell migration GO:0014911 4 0.120
regulation of hydrolase activity GO:0051336 246 0.119
positive regulation of cell projection organization GO:0031346 95 0.119
purine ribonucleoside metabolic process GO:0046128 241 0.119
cellular amino acid metabolic process GO:0006520 103 0.118
regulation of epithelial cell migration GO:0010632 35 0.118
regulation of bmp signaling pathway GO:0030510 60 0.117
regulation of actin polymerization or depolymerization GO:0008064 45 0.117
cellular response to radiation GO:0071478 28 0.116
epithelial cell migration GO:0010631 63 0.115
Fly
lens development in camera type eye GO:0002088 62 0.115
cellular response to retinoic acid GO:0071300 25 0.114
Mouse
tissue migration GO:0090130 68 0.114
Fly
regulation of endothelial cell chemotaxis GO:2001026 1 0.114
blood vessel endothelial cell migration GO:0043534 23 0.114
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.114
ras protein signal transduction GO:0007265 77 0.114
salivary gland development GO:0007431 37 0.113
proteasomal protein catabolic process GO:0010498 98 0.112
t cell activation GO:0042110 289 0.112
epithelial cell morphogenesis GO:0003382 41 0.110
gland development GO:0048732 330 0.109
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.109
Human
gastrulation GO:0007369 116 0.109
hair cycle GO:0042633 90 0.109
ensheathment of neurons GO:0007272 76 0.109
cell chemotaxis GO:0060326 81 0.109
morphogenesis of a branching epithelium GO:0061138 193 0.108
actin filament polymerization GO:0030041 44 0.108
nucleoside triphosphate metabolic process GO:0009141 230 0.108
protein modification by small protein conjugation or removal GO:0070647 207 0.106
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.105
mesodermal cell migration GO:0008078 4 0.105
regulation of metanephros development GO:0072215 15 0.104
regulation of mapk cascade GO:0043408 248 0.104
positive regulation of protein modification process GO:0031401 299 0.104
protein ubiquitination GO:0016567 171 0.103
ubiquitin dependent protein catabolic process GO:0006511 129 0.103
regulation of organelle organization GO:0033043 289 0.103
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.101
Mouse
molting cycle GO:0042303 90 0.101
metanephric glomerular mesangium development GO:0072223 3 0.101
purine containing compound catabolic process GO:0072523 213 0.100
organelle fission GO:0048285 170 0.099
respiratory system development GO:0060541 190 0.099
b cell activation GO:0042113 161 0.099
cardiac cell development GO:0055006 41 0.099
regulation of endothelial cell migration GO:0010594 22 0.098
somatic stem cell maintenance GO:0035019 47 0.098
Mouse
ribonucleotide catabolic process GO:0009261 208 0.098
positive regulation of chemotaxis GO:0050921 38 0.098
regulation of vasculature development GO:1901342 88 0.098
guanosine containing compound metabolic process GO:1901068 144 0.097
rho protein signal transduction GO:0007266 32 0.097
modification dependent macromolecule catabolic process GO:0043632 133 0.097
salivary gland morphogenesis GO:0007435 33 0.097
regulation of body fluid levels GO:0050878 162 0.096
apoptotic signaling pathway GO:0097190 306 0.096
Mouse
negative regulation of cell proliferation GO:0008285 296 0.096
osteoclast differentiation GO:0030316 62 0.093
response to oxygen levels GO:0070482 62 0.093
response to ionizing radiation GO:0010212 42 0.092
meiotic cell cycle GO:0051321 122 0.092
macromolecule catabolic process GO:0009057 281 0.091
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.091
cell substrate junction assembly GO:0007044 24 0.091
epidermis morphogenesis GO:0048730 33 0.089
action potential GO:0001508 78 0.089
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.089
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.089
Human
gtp catabolic process GO:0006184 143 0.087
regulation of action potential GO:0098900 4 0.087
negative regulation of protein processing GO:0010955 79 0.086
cell substrate adherens junction assembly GO:0007045 19 0.086
glial cell differentiation GO:0010001 131 0.086
cellular response to ionizing radiation GO:0071479 11 0.086
positive regulation of bmp signaling pathway GO:0030513 23 0.085
regulation of cytoskeleton organization GO:0051493 122 0.085
purine ribonucleoside catabolic process GO:0046130 205 0.084
spermatid development GO:0007286 108 0.084
regulation of intracellular transport GO:0032386 159 0.083
Human
stress activated mapk cascade GO:0051403 80 0.083
actomyosin structure organization GO:0031032 56 0.083
cardiac muscle cell development GO:0055013 39 0.083
purine nucleoside catabolic process GO:0006152 205 0.083
positive regulation of cell substrate adhesion GO:0010811 47 0.082
response to peptide GO:1901652 136 0.082
cardiac muscle tissue morphogenesis GO:0055008 44 0.081
regulation of anatomical structure size GO:0090066 178 0.080
regulation of vesicle mediated transport GO:0060627 139 0.080
endocardial cell differentiation GO:0060956 4 0.080
positive regulation of map kinase activity GO:0043406 84 0.079
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.079
Human
negative regulation of osteoblast differentiation GO:0045668 30 0.079
regulation of nucleoside metabolic process GO:0009118 130 0.079
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.079
cellular response to abiotic stimulus GO:0071214 56 0.079
muscle cell migration GO:0014812 19 0.078
spermatogenesis GO:0007283 284 0.078
apical constriction GO:0003383 4 0.077
regulation of osteoblast proliferation GO:0033688 15 0.077
cardiac muscle tissue development GO:0048738 130 0.077
dendrite development GO:0016358 115 0.077
regulation of keratinocyte proliferation GO:0010837 15 0.077
Mouse
regulation of cell cycle process GO:0010564 160 0.076
regulation of gtp catabolic process GO:0033124 113 0.076
purine ribonucleotide catabolic process GO:0009154 208 0.076
regulation of membrane potential GO:0042391 192 0.076
myotube differentiation GO:0014902 105 0.076
negative regulation of phosphorylation GO:0042326 166 0.076
Human
positive regulation of hydrolase activity GO:0051345 148 0.075
positive regulation of epithelial cell migration GO:0010634 19 0.075
regulation of cellular ketone metabolic process GO:0010565 66 0.075
limb development GO:0060173 166 0.074
adherens junction assembly GO:0034333 22 0.074
sensory perception GO:0007600 245 0.074
digestive tract morphogenesis GO:0048546 147 0.074
development of primary sexual characteristics GO:0045137 143 0.074
regulation of fibroblast growth factor production GO:0090270 4 0.074
regulation of chemotaxis GO:0050920 53 0.074
brown fat cell differentiation GO:0050873 36 0.074
cardiac septum development GO:0003279 59 0.073
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.073
peptidyl amino acid modification GO:0018193 336 0.073
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.072
regulation of epithelial to mesenchymal transition GO:0010717 22 0.072
Human
establishment of cell polarity involved in ameboidal cell migration GO:0003365 2 0.072
regulation of smad protein import into nucleus GO:0060390 3 0.072
Human
extracellular structure organization GO:0043062 148 0.072
positive regulation of endothelial cell migration GO:0010595 12 0.071
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.070
nucleoside phosphate catabolic process GO:1901292 222 0.070
trophectodermal cell differentiation GO:0001829 21 0.070
negative regulation of ossification GO:0030279 49 0.070
circulatory system process GO:0003013 197 0.070
regulation of glomerular filtration GO:0003093 3 0.069
digestive system development GO:0055123 200 0.069
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.069
positive regulation of cell adhesion GO:0045785 80 0.067
endothelial cell differentiation GO:0045446 41 0.067
ribose phosphate metabolic process GO:0019693 291 0.066
axon ensheathment GO:0008366 76 0.066
renal tubule morphogenesis GO:0061333 72 0.065
striated muscle myosin thick filament assembly GO:0071688 1 0.065
cardiac endothelial cell differentiation GO:0003348 4 0.064
neuropilin signaling pathway GO:0038189 2 0.064
smooth muscle cell migration GO:0014909 10 0.064
nucleotide catabolic process GO:0009166 217 0.063
regulation of wound healing GO:0061041 40 0.063
regulation of osteoblast differentiation GO:0045667 67 0.063
heart process GO:0003015 94 0.062
negative regulation of protein phosphorylation GO:0001933 126 0.062
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.062
Human
regulation of neuron projection development GO:0010975 169 0.061
regulation of p38mapk cascade GO:1900744 3 0.061
endomembrane system organization GO:0010256 147 0.061
ribonucleoside metabolic process GO:0009119 245 0.061
negative regulation of kinase activity GO:0033673 81 0.061
Human
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.061
regulation of actin filament polymerization GO:0030833 38 0.061
labyrinthine layer development GO:0060711 49 0.061
striated muscle cell development GO:0055002 125 0.060
regulation of cysteine type endopeptidase activity GO:2000116 65 0.060
regulation of fat cell differentiation GO:0045598 81 0.060
purine nucleoside triphosphate catabolic process GO:0009146 203 0.060
regulation of transmembrane transport GO:0034762 128 0.060
blastocyst formation GO:0001825 33 0.060
response to transforming growth factor beta GO:0071559 88 0.060
glial cell proliferation GO:0014009 10 0.060
Fly
regulation of striated muscle cell differentiation GO:0051153 81 0.060
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.060
nucleoside metabolic process GO:0009116 246 0.059
actin mediated cell contraction GO:0070252 15 0.059
regulation of protein transport GO:0051223 163 0.059
Human
organic cyclic compound catabolic process GO:1901361 295 0.059
endocytosis GO:0006897 168 0.058
positive regulation of mapk cascade GO:0043410 170 0.058
positive regulation of organ growth GO:0046622 29 0.057
Mouse
divalent inorganic cation transport GO:0072511 178 0.057
organ growth GO:0035265 117 0.057
Mouse
regulation of organ growth GO:0046620 61 0.057
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.057
Human
nucleocytoplasmic transport GO:0006913 139 0.057
Human
branching morphogenesis of an epithelial tube GO:0048754 159 0.056
cell growth GO:0016049 130 0.056
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.056
retina vasculature development in camera type eye GO:0061298 17 0.056
membrane organization GO:0061024 245 0.056
response to peptide hormone GO:0043434 127 0.055
mapk cascade GO:0000165 281 0.055
actin filament based movement GO:0030048 23 0.055
skeletal system morphogenesis GO:0048705 203 0.055
filopodium assembly GO:0046847 19 0.055
mitotic cell cycle GO:0000278 195 0.054
vascular process in circulatory system GO:0003018 62 0.054
renal system process GO:0003014 48 0.054
forebrain cell migration GO:0021885 58 0.053
negative regulation of cellular amine metabolic process GO:0033239 1 0.053
carbohydrate homeostasis GO:0033500 128 0.053
chemotaxis GO:0006935 247 0.053
nuclear division GO:0000280 158 0.053
negative regulation of epithelial cell proliferation GO:0050680 64 0.052
neuron projection guidance GO:0097485 141 0.052
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.052
posttranscriptional regulation of gene expression GO:0010608 155 0.052
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.051
regulation of skeletal muscle adaptation GO:0014733 12 0.051
membrane lipid metabolic process GO:0006643 53 0.051
somite development GO:0061053 81 0.051
regulation of protein maturation GO:1903317 96 0.051
ear development GO:0043583 200 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.050
positive regulation of endothelial cell chemotaxis GO:2001028 1 0.049
positive regulation of phospholipase activity GO:0010518 3 0.049
positive regulation of epithelial cell proliferation GO:0050679 68 0.049
neural precursor cell proliferation GO:0061351 121 0.049
positive regulation of vasoconstriction GO:0045907 4 0.049
heterocycle catabolic process GO:0046700 280 0.048
aromatic compound catabolic process GO:0019439 286 0.048
gonad development GO:0008406 141 0.048
regulation of kidney development GO:0090183 40 0.048
positive regulation of programmed cell death GO:0043068 218 0.048
chondroblast differentiation GO:0060591 2 0.048
metanephros development GO:0001656 79 0.048
spermatid differentiation GO:0048515 115 0.048
hematopoietic progenitor cell differentiation GO:0002244 143 0.047
g protein coupled receptor signaling pathway GO:0007186 243 0.047
apical junction assembly GO:0043297 15 0.047
labyrinthine layer morphogenesis GO:0060713 21 0.047
cellular response to organonitrogen compound GO:0071417 145 0.046
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.046
protein localization to membrane GO:0072657 108 0.046
cellular response to oxidative stress GO:0034599 76 0.045
inflammatory response GO:0006954 244 0.045
germ cell development GO:0007281 185 0.045
Fly
positive regulation of cell cycle GO:0045787 92 0.045
peripheral nervous system development GO:0007422 53 0.044
cellular response to peptide hormone stimulus GO:0071375 92 0.044
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.044
paraxial mesoderm development GO:0048339 18 0.044
Mouse
receptor mediated endocytosis GO:0006898 51 0.044
establishment of tissue polarity GO:0007164 28 0.044
response to hypoxia GO:0001666 58 0.043
negative regulation of response to wounding GO:1903035 77 0.043
positive regulation of apoptotic process GO:0043065 217 0.043
wound healing spreading of cells GO:0044319 8 0.043
protein localization to endosome GO:0036010 2 0.043
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.043
blastocyst development GO:0001824 80 0.043
protein import GO:0017038 101 0.043
Human
neuron death GO:0070997 154 0.042
muscle cell development GO:0055001 133 0.042
mitotic cell cycle process GO:1903047 159 0.042
establishment of protein localization to membrane GO:0090150 54 0.042
regulation of cellular catabolic process GO:0031329 242 0.042
regulation of neuron apoptotic process GO:0043523 122 0.042
negative regulation of nervous system development GO:0051961 156 0.042
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
regulation of branching involved in salivary gland morphogenesis by extracellular matrix epithelial cell signaling GO:0060668 1 0.041
negative regulation of cell adhesion GO:0007162 45 0.041
vegf activated neuropilin signaling pathway GO:0038190 2 0.041
peptidyl tyrosine modification GO:0018212 145 0.041
metanephric glomerular basement membrane development GO:0072274 1 0.041
regulation of cell growth GO:0001558 91 0.041
ear morphogenesis GO:0042471 118 0.041
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.041
positive regulation of protein kinase c signaling GO:0090037 1 0.041
mitral valve development GO:0003174 4 0.041
blood coagulation GO:0007596 76 0.041
negative regulation of angiogenesis GO:0016525 25 0.041
regulation of synaptic plasticity GO:0048167 87 0.040
regulation of smooth muscle cell migration GO:0014910 6 0.040
heart contraction GO:0060047 93 0.040
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.040
glycerolipid metabolic process GO:0046486 122 0.040
regulation of nucleotide catabolic process GO:0030811 122 0.040
lateral mesoderm development GO:0048368 13 0.040
Mouse
negative regulation of protein modification process GO:0031400 163 0.040
Human
muscle tissue morphogenesis GO:0060415 53 0.040
regulation of map kinase activity GO:0043405 120 0.039

Wwtr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.070
muscular disease DOID:0080000 0 0.070
heart disease DOID:114 0 0.070
cardiomyopathy DOID:0050700 0 0.070
disease of anatomical entity DOID:7 0 0.070
intrinsic cardiomyopathy DOID:0060036 0 0.070
cardiovascular system disease DOID:1287 0 0.070
musculoskeletal system disease DOID:17 0 0.070
muscle tissue disease DOID:66 0 0.070
nervous system disease DOID:863 0 0.061
disease of cellular proliferation DOID:14566 0 0.044