|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.735
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.706
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.680
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.634
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.600
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.486
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.405
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.385
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.385
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.369
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.365
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.364
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.348
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.341
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.328
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.324
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.312
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.299
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.296
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.288
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.286
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.285
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.271
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.268
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.265
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.257
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.256
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.246
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.243
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.234
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.232
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.229
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.225
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.217
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.216
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.215
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.214
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.212
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.211
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.210
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.209
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.203
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.200
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.187
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.183
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.178
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.177
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.174
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.170
|
Mouse |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.167
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.167
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.164
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.162
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.160
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.159
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.157
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.155
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.155
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.153
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.151
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.151
|
|
|
|
regulation of anti mullerian hormone signaling pathway
|
GO:1902612 |
1 |
0.151
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.150
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.149
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.144
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.144
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.143
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.141
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.141
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.138
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.137
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
19 |
0.135
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.135
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.135
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.134
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.132
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.131
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.130
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
3 |
0.128
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.128
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.128
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.127
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.126
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.126
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.125
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.124
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.123
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.122
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.121
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.120
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.119
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.118
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.118
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.118
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.118
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.118
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.115
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.113
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.113
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.112
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.110
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.108
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.106
|
|
|
|
bronchus morphogenesis
|
GO:0060434 |
2 |
0.106
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.106
|
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.106
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
49 |
0.106
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.105
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.103
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.100
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.100
|
|
|
|
negative regulation of endothelial cell differentiation
|
GO:0045602 |
2 |
0.100
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.099
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.098
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.096
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.096
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.096
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.096
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.096
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.094
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.094
|
|
|
|
lens fiber cell apoptotic process
|
GO:1990086 |
4 |
0.093
|
|
|
|
phosphatidylinositol phosphorylation
|
GO:0046854 |
23 |
0.093
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.090
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.089
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.089
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.088
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.088
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.088
|
Rat |
|
|
regulation of lung blood pressure
|
GO:0014916 |
2 |
0.088
|
|
|
|
lateral mesodermal cell fate commitment
|
GO:0048372 |
2 |
0.087
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.087
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.087
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.086
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.085
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.085
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.085
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.084
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.082
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.082
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.081
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.080
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.079
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.078
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.078
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.078
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.078
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.077
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.077
|
|
|
|
lateral mesodermal cell differentiation
|
GO:0048371 |
3 |
0.076
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.076
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.075
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.075
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.074
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.074
|
Mouse |
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.074
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.074
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.074
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.074
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.074
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.073
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.073
|
|
|
|
regulation of b cell tolerance induction
|
GO:0002661 |
2 |
0.072
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.071
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.071
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.071
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.071
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.070
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.070
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
4 |
0.070
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.069
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.068
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.068
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
6 |
0.068
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.066
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.066
|
|
|
|
maintenance of protein location in nucleus
|
GO:0051457 |
2 |
0.066
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.066
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.066
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.065
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.065
|
Rat |
|
|
neuron death
|
GO:0070997 |
154 |
0.064
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.064
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.063
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.063
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.063
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.063
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.063
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.061
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.061
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.061
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.061
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
2 |
0.061
|
|
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.061
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.060
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.060
|
|
|
|
regulation of tolerance induction to self antigen
|
GO:0002649 |
1 |
0.060
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.060
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.060
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.060
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.060
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.059
|
Mouse |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.059
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.059
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.059
|
Human |
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.058
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
13 |
0.057
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.057
|
Mouse |
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
37 |
0.057
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.056
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.056
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.056
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.056
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.056
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.056
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.056
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.056
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.055
|
Human |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.055
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.055
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.055
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.054
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.054
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.054
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.054
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.054
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.053
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.053
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.053
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.052
|
|
|
|
trachea formation
|
GO:0060440 |
3 |
0.052
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.052
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.052
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.052
|
|
|
|
axon extension involved in axon guidance
|
GO:0048846 |
14 |
0.051
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.051
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.050
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.050
|
|
|
|
fused antrum stage
|
GO:0048165 |
1 |
0.050
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.050
|
Mouse |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.049
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.049
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.049
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.049
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.049
|
Human |
|
|
organic anion transport
|
GO:0015711 |
137 |
0.049
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.048
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.048
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.048
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.048
|
|
|
|
lateral mesoderm morphogenesis
|
GO:0048369 |
3 |
0.047
|
|
|
|
memory
|
GO:0007613 |
58 |
0.047
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.047
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.047
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.047
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.047
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.046
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.046
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.046
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.046
|
|
|
|
neural crest cell migration
|
GO:0001755 |
32 |
0.046
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.046
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.046
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.045
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.045
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.045
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.045
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.045
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.045
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.045
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.044
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.044
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.044
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.044
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.044
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.043
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.043
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.043
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.043
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.043
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.043
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.042
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.042
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.042
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.042
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.042
|
|
|
|
mesoderm structural organization
|
GO:0048338 |
1 |
0.042
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.042
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.042
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.041
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.041
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
29 |
0.041
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.041
|
|
|
|
positive regulation of tolerance induction to self antigen
|
GO:0002651 |
1 |
0.041
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.041
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.041
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.041
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.041
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.040
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.040
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.040
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.040
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.040
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.040
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.040
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.040
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.039
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.039
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.039
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.039
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.039
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.039
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.039
|
|
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
1 |
0.039
|
|
|
|
chondrocyte hypertrophy
|
GO:0003415 |
4 |
0.039
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.039
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.039
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.039
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.038
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.038
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.038
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.038
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
17 |
0.038
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.038
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.038
|
Rat |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.038
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.038
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.038
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.038
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.037
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.037
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.037
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.037
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.037
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.037
|
|
|
|
growth plate cartilage chondrocyte development
|
GO:0003431 |
3 |
0.037
|
|
|
|
regulation of p38mapk cascade
|
GO:1900744 |
3 |
0.037
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.037
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.036
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.036
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.036
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.036
|
|
|
|
neural plate mediolateral regionalization
|
GO:0021998 |
1 |
0.036
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.036
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.036
|
|
|
|
visual perception
|
GO:0007601 |
52 |
0.036
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.036
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.036
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.036
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.036
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.036
|
|
|
|
positive regulation of b cell tolerance induction
|
GO:0002663 |
2 |
0.035
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.035
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.035
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.035
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.035
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.035
|
|
|
|
anatomical structure arrangement
|
GO:0048532 |
20 |
0.035
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.035
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.034
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.034
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.034
|
|
|
|
oogenesis stage
|
GO:0022605 |
3 |
0.034
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.034
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.034
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.034
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.034
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.033
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.033
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.033
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.033
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
24 |
0.033
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.033
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.033
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.033
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.033
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.033
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.033
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.032
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.032
|
|
|
|
response to cholesterol
|
GO:0070723 |
4 |
0.032
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
71 |
0.032
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.032
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.032
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.032
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.031
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.031
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.031
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.031
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.031
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.031
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.031
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.031
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.031
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.031
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.031
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.031
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.031
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.031
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.031
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.030
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.030
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.030
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.030
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.030
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.030
|
|
|
|
positive regulation of axon guidance
|
GO:1902669 |
5 |
0.030
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.030
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.030
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.030
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.030
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.029
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.029
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.029
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.029
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.029
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.029
|
|
|
|
regulation of lateral mesodermal cell fate specification
|
GO:0048378 |
2 |
0.029
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.029
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.029
|
|
|
|
mullerian duct regression
|
GO:0001880 |
1 |
0.029
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.029
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.028
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.028
|
|
|
|
paraxial mesoderm structural organization
|
GO:0048352 |
1 |
0.028
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.028
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.028
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.028
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.028
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.028
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.028
|
|
|
|
negative regulation of anti mullerian hormone signaling pathway
|
GO:1902613 |
1 |
0.028
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.027
|
|
|
|
cellular magnesium ion homeostasis
|
GO:0010961 |
3 |
0.027
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.027
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.027
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.027
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.027
|
|
|
|
spindle assembly involved in mitosis
|
GO:0090307 |
4 |
0.027
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.027
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
3 |
0.027
|
|
|
|
negative regulation of vasoconstriction
|
GO:0045906 |
2 |
0.027
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.027
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.027
|
|
|
|
dna dependent dna replication maintenance of fidelity
|
GO:0045005 |
3 |
0.027
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.027
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.027
|
|
|
|
platelet morphogenesis
|
GO:0036344 |
13 |
0.027
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.027
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.026
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
20 |
0.026
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.026
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.026
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.026
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.026
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.026
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.026
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.026
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.026
|
|
|
|
lateral mesodermal cell fate specification
|
GO:0048377 |
2 |
0.026
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.026
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.026
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.026
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.026
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.026
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.025
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.025
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.025
|
|
|
|
forebrain neuron development
|
GO:0021884 |
30 |
0.025
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.025
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.025
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.025
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.025
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.025
|
|
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.025
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.025
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.025
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
23 |
0.025
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.025
|
|
|
|
nk t cell differentiation
|
GO:0001865 |
8 |
0.024
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
6 |
0.024
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.024
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.024
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.024
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.024
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.024
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.024
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.024
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.024
|
|
