Mus musculus

59 known processes

Xpc

xeroderma pigmentosum, complementation group C

Xpc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.192
dna repair GO:0006281 107 0.087
cellular response to dna damage stimulus GO:0006974 207 0.072
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
nucleoside phosphate metabolic process GO:0006753 338 0.057
protein catabolic process GO:0030163 221 0.055
nucleotide excision repair GO:0006289 13 0.052
cellular amino acid metabolic process GO:0006520 103 0.050
ribonucleotide metabolic process GO:0009259 291 0.049
modification dependent macromolecule catabolic process GO:0043632 133 0.049
macromolecule catabolic process GO:0009057 281 0.047
intrinsic apoptotic signaling pathway GO:0097193 132 0.046
cellular macromolecule catabolic process GO:0044265 206 0.046
cellular protein catabolic process GO:0044257 155 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.043
apoptotic signaling pathway GO:0097190 306 0.043
cellular amine metabolic process GO:0044106 44 0.043
nucleotide metabolic process GO:0009117 332 0.041
modification dependent protein catabolic process GO:0019941 133 0.041
multicellular organism growth GO:0035264 161 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
cellular ketone metabolic process GO:0042180 84 0.039
regulation of cellular catabolic process GO:0031329 242 0.038
oxidation reduction process GO:0055114 342 0.037
purine nucleotide catabolic process GO:0006195 211 0.036
protein ubiquitination GO:0016567 171 0.036
organic cyclic compound catabolic process GO:1901361 295 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
heterocycle catabolic process GO:0046700 280 0.032
response to light stimulus GO:0009416 135 0.032
male gamete generation GO:0048232 285 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
mitochondrial dna replication GO:0006264 7 0.031
lung development GO:0030324 164 0.031
response to radiation GO:0009314 165 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
amine metabolic process GO:0009308 45 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
purine nucleotide metabolic process GO:0006163 302 0.028
purine containing compound metabolic process GO:0072521 311 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.026
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.026
mitotic cell cycle process GO:1903047 159 0.026
chromatin modification GO:0016568 187 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.025
response to uv GO:0009411 44 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
organonitrogen compound catabolic process GO:1901565 264 0.023
ras protein signal transduction GO:0007265 77 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
leukocyte differentiation GO:0002521 342 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
stem cell differentiation GO:0048863 268 0.022
spermatogenesis GO:0007283 284 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
regulation of proteolysis GO:0030162 164 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
regulation of hydrolase activity GO:0051336 246 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
organophosphate catabolic process GO:0046434 232 0.019
negative regulation of protein modification process GO:0031400 163 0.019
respiratory tube development GO:0030323 167 0.018
aromatic compound catabolic process GO:0019439 286 0.018
kidney development GO:0001822 213 0.018
striated muscle tissue development GO:0014706 293 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
response to oxidative stress GO:0006979 123 0.017
regulation of protein catabolic process GO:0042176 108 0.017
cell type specific apoptotic process GO:0097285 268 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
nucleoside metabolic process GO:0009116 246 0.017
transmembrane transport GO:0055085 412 0.017
maintenance of location GO:0051235 89 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
mitochondrial genome maintenance GO:0000002 15 0.016
response to nutrient levels GO:0031667 109 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
gtp catabolic process GO:0006184 143 0.016
response to extracellular stimulus GO:0009991 127 0.016
action potential GO:0001508 78 0.015
positive regulation of protein modification process GO:0031401 299 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
renal system development GO:0072001 225 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
cellular response to extracellular stimulus GO:0031668 81 0.015
cofactor metabolic process GO:0051186 80 0.015
regulation of membrane potential GO:0042391 192 0.014
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.014
regulation of feeding behavior GO:0060259 3 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
negative regulation of cell cycle GO:0045786 123 0.014
regulation of organelle organization GO:0033043 289 0.014
homeostasis of number of cells GO:0048872 210 0.014
cytokine production GO:0001816 319 0.014
mitochondrial dna metabolic process GO:0032042 13 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
response to growth factor GO:0070848 198 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
negative regulation of organelle organization GO:0010639 90 0.013
regulation of defense response GO:0031347 233 0.013
regulation of cytokine production GO:0001817 266 0.013
sensory perception GO:0007600 245 0.013
tube formation GO:0035148 140 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
immune response activating signal transduction GO:0002757 116 0.013
regulation of cell activation GO:0050865 289 0.013
muscle tissue development GO:0060537 308 0.013
digestive tract development GO:0048565 190 0.013
peptidyl amino acid modification GO:0018193 336 0.013
nucleoside catabolic process GO:0009164 206 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
blood circulation GO:0008015 195 0.012
positive regulation of dna templated transcription elongation GO:0032786 2 0.012
response to uv c GO:0010225 3 0.012
interleukin 8 production GO:0032637 4 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
atp metabolic process GO:0046034 75 0.012
cation transmembrane transport GO:0098655 266 0.012
fat cell differentiation GO:0045444 160 0.012
adaptive immune response GO:0002250 155 0.012
myeloid cell differentiation GO:0030099 233 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
dephosphorylation GO:0016311 129 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of mitotic cell cycle GO:0007346 126 0.011
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.011
t cell activation GO:0042110 289 0.011
cardiac chamber development GO:0003205 108 0.011
forebrain development GO:0030900 302 0.011
protein localization to membrane GO:0072657 108 0.011
myeloid cell homeostasis GO:0002262 114 0.011
embryonic limb morphogenesis GO:0030326 126 0.011
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.011
protein localization to nucleus GO:0034504 121 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of kinase activity GO:0043549 249 0.011
mitotic cell cycle GO:0000278 195 0.011
positive regulation of nervous system development GO:0051962 221 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
appendage development GO:0048736 166 0.011
protein acylation GO:0043543 64 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
myosin filament organization GO:0031033 3 0.011
single organism cell adhesion GO:0098602 156 0.011
male genitalia morphogenesis GO:0048808 4 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
cytoplasmic transport GO:0016482 234 0.011
cellular lipid metabolic process GO:0044255 323 0.011
nitrogen compound transport GO:0071705 271 0.011
gene silencing by mirna GO:0035195 10 0.011
digestive system development GO:0055123 200 0.011
positive regulation of gene silencing by mirna GO:2000637 1 0.010
neuronal action potential GO:0019228 54 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
neural tube closure GO:0001843 90 0.010
response to organonitrogen compound GO:0010243 246 0.010
locomotory behavior GO:0007626 195 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010
synaptic transmission GO:0007268 329 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
gtp metabolic process GO:0046039 144 0.010
membrane organization GO:0061024 245 0.010
epithelial cell proliferation GO:0050673 174 0.010
negative regulation of nervous system development GO:0051961 156 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
cerebellum development GO:0021549 77 0.010
muscle cell differentiation GO:0042692 261 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010

Xpc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.011