Mus musculus

79 known processes

Xpo1

exportin 1, CRM1 homolog (yeast)

(Aliases: Crm1,Exp1,AA420417)

Xpo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.474
dna templated transcription termination GO:0006353 4 0.314
rna 3 end processing GO:0031123 20 0.277
microtubule cytoskeleton organization GO:0000226 157 0.239
rna interference GO:0016246 2 0.221
development of primary sexual characteristics GO:0045137 143 0.210
organelle fission GO:0048285 170 0.198
meiotic cell cycle GO:0051321 122 0.178
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.163
mitotic cell cycle process GO:1903047 159 0.162
mitotic nuclear division GO:0007067 48 0.160
macromolecule catabolic process GO:0009057 281 0.152
cellular amino acid metabolic process GO:0006520 103 0.144
nuclear division GO:0000280 158 0.135
dna replication GO:0006260 52 0.118
interspecies interaction between organisms GO:0044419 83 0.096
meiotic nuclear division GO:0007126 115 0.094
protein complex disassembly GO:0043241 40 0.091
mitotic cell cycle GO:0000278 195 0.087
cell division GO:0051301 120 0.084
regulation of cell cycle GO:0051726 281 0.082
cellular nitrogen compound catabolic process GO:0044270 280 0.081
mitotic chromosome condensation GO:0007076 1 0.078
cellular response to dna damage stimulus GO:0006974 207 0.074
cellular ketone metabolic process GO:0042180 84 0.073
mitotic sister chromatid segregation GO:0000070 14 0.072
regulation of mitotic cell cycle GO:0007346 126 0.071
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.071
chromosome segregation GO:0007059 48 0.070
germ cell development GO:0007281 185 0.068
regulation of protein complex disassembly GO:0043244 28 0.068
nucleocytoplasmic transport GO:0006913 139 0.066
gene silencing by rna GO:0031047 19 0.064
regulation of cell projection organization GO:0031344 206 0.063
cellular macromolecule catabolic process GO:0044265 206 0.062
gonad development GO:0008406 141 0.061
regulation of organelle organization GO:0033043 289 0.059
meiotic cell cycle process GO:1903046 77 0.058
posttranscriptional regulation of gene expression GO:0010608 155 0.057
response to heat GO:0009408 27 0.051
microtubule based process GO:0007017 236 0.051
negative regulation of protein metabolic process GO:0051248 282 0.049
macromolecular complex disassembly GO:0032984 43 0.049
regulation of cellular catabolic process GO:0031329 242 0.046
amine metabolic process GO:0009308 45 0.045
organelle localization GO:0051640 179 0.044
Human Yeast
posttranscriptional gene silencing by rna GO:0035194 10 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.038
receptor mediated endocytosis GO:0006898 51 0.038
microtubule organizing center organization GO:0031023 28 0.037
regulation of cell cycle process GO:0010564 160 0.037
negative regulation of immunoglobulin mediated immune response GO:0002890 7 0.036
mitotic sister chromatid cohesion GO:0007064 1 0.036
regulation of neuron projection development GO:0010975 169 0.036
establishment of organelle localization GO:0051656 122 0.036
Human Yeast
regulation of cellular component biogenesis GO:0044087 181 0.035
cellular component assembly involved in morphogenesis GO:0010927 139 0.035
ras protein signal transduction GO:0007265 77 0.035
dna repair GO:0006281 107 0.034
chromosome organization involved in meiosis GO:0070192 39 0.033
negative regulation of synapse assembly GO:0051964 3 0.033
cellular amine metabolic process GO:0044106 44 0.032
organelle assembly GO:0070925 177 0.032
Fly
intracellular protein transport GO:0006886 204 0.032
nucleic acid transport GO:0050657 18 0.031
Yeast
ossification GO:0001503 216 0.031
regulation of translation GO:0006417 71 0.031
response to peptide GO:1901652 136 0.031
negative regulation of cell cycle process GO:0010948 69 0.030
regulation of neuron differentiation GO:0045664 281 0.029
dendrite development GO:0016358 115 0.029
rna localization GO:0006403 23 0.029
Yeast
regulation of mrna stability GO:0043488 23 0.029
lateral inhibition GO:0046331 1 0.028
regulation of nuclear division GO:0051783 56 0.028
gene silencing GO:0016458 38 0.027
female gamete generation GO:0007292 74 0.027
rna transport GO:0050658 18 0.027
Yeast
heterocycle catabolic process GO:0046700 280 0.027
aromatic compound catabolic process GO:0019439 286 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
circulatory system process GO:0003013 197 0.025
nitrogen compound transport GO:0071705 271 0.025
Yeast
centrosome organization GO:0051297 26 0.024
regulation of cell cycle phase transition GO:1901987 77 0.024
centrosome cycle GO:0007098 23 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.023
cell cycle checkpoint GO:0000075 47 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
meiotic chromosome segregation GO:0045132 19 0.023
skin development GO:0043588 220 0.023
rna processing GO:0006396 105 0.022
nuclear transport GO:0051169 139 0.022
cell type specific apoptotic process GO:0097285 268 0.022
rna stabilization GO:0043489 9 0.022
maintenance of location GO:0051235 89 0.021
cytoplasmic transport GO:0016482 234 0.021
cellular lipid metabolic process GO:0044255 323 0.021
kinetochore organization GO:0051383 2 0.021
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
cardiac muscle contraction GO:0060048 32 0.020
oocyte construction GO:0007308 2 0.020
translation GO:0006412 93 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
mrna transport GO:0051028 13 0.019
Yeast
posttranscriptional gene silencing GO:0016441 10 0.019
dna recombination GO:0006310 92 0.019
response to oxidative stress GO:0006979 123 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.018
negative regulation of viral process GO:0048525 23 0.018
male gamete generation GO:0048232 285 0.018
cellular response to oxidative stress GO:0034599 76 0.018
positive regulation of cell cycle GO:0045787 92 0.018
neuron migration GO:0001764 122 0.017
response to radiation GO:0009314 165 0.017
mrna stabilization GO:0048255 9 0.017
nuclear mrna surveillance GO:0071028 1 0.016
muscle contraction GO:0006936 101 0.016
mrna catabolic process GO:0006402 22 0.016
negative regulation of cell cycle GO:0045786 123 0.016
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
regulation of circadian rhythm GO:0042752 58 0.016
cell maturation GO:0048469 127 0.016
actin cytoskeleton organization GO:0030036 220 0.016
muscle system process GO:0003012 141 0.016
spermatid development GO:0007286 108 0.016
nucleus organization GO:0006997 45 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
endocytosis GO:0006897 168 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
regulation of rna splicing GO:0043484 37 0.015
regulation of dna replication GO:0006275 17 0.015
positive regulation of nervous system development GO:0051962 221 0.015
cellular protein catabolic process GO:0044257 155 0.015
b cell activation GO:0042113 161 0.014
genitalia development GO:0048806 37 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
axonogenesis GO:0007409 274 0.014
single fertilization GO:0007338 82 0.014
spermine metabolic process GO:0008215 3 0.014
regulation of multi organism process GO:0043900 111 0.014
cell recognition GO:0008037 83 0.014
regionalization GO:0003002 337 0.014
nucleobase containing compound transport GO:0015931 27 0.014
Yeast
heart contraction GO:0060047 93 0.014
interaction with symbiont GO:0051702 14 0.014
epidermis development GO:0008544 187 0.014
negative regulation of cell projection organization GO:0031345 56 0.014
blood circulation GO:0008015 195 0.014
small gtpase mediated signal transduction GO:0007264 97 0.013
methylation GO:0032259 134 0.013
mrna metabolic process GO:0016071 84 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
protein catabolic process GO:0030163 221 0.013
response to inorganic substance GO:0010035 96 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
lipid localization GO:0010876 126 0.013
positive regulation of cell cycle process GO:0090068 61 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
negative regulation of neuron projection development GO:0010977 50 0.012
heart process GO:0003015 94 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
muscle cell differentiation GO:0042692 261 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
response to extracellular stimulus GO:0009991 127 0.012
mitotic spindle organization GO:0007052 10 0.012
establishment of rna localization GO:0051236 18 0.012
Yeast
sister chromatid segregation GO:0000819 20 0.012
rna export from nucleus GO:0006405 15 0.012
Yeast
response to light stimulus GO:0009416 135 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
regulation of actin filament based process GO:0032970 99 0.011
regulation of microtubule based process GO:0032886 52 0.011
response to transforming growth factor beta GO:0071559 88 0.011
dna alkylation GO:0006305 43 0.011
dna catabolic process exonucleolytic GO:0000738 3 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
cellular protein complex assembly GO:0043623 116 0.011
actomyosin structure organization GO:0031032 56 0.011
negative regulation of multi organism process GO:0043901 68 0.011
regulation of dna templated transcription termination GO:0031554 1 0.011
3 utr mediated mrna stabilization GO:0070935 2 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
neuron death GO:0070997 154 0.010
cellular response to metal ion GO:0071248 31 0.010
response to peptide hormone GO:0043434 127 0.010
protein import into nucleus GO:0006606 95 0.010
anatomical structure homeostasis GO:0060249 145 0.010
regulation of cellular amine metabolic process GO:0033238 20 0.010
dna dependent dna replication GO:0006261 24 0.010
negative regulation of cell development GO:0010721 169 0.010
viral gene expression GO:0019080 3 0.010
stem cell development GO:0048864 219 0.010
regulation of cell division GO:0051302 76 0.010
metaphase plate congression GO:0051310 2 0.010

Xpo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
central nervous system disease DOID:331 0 0.030
neurodegenerative disease DOID:1289 0 0.023