Mus musculus

236 known processes

Yap1

yes-associated protein 1

(Aliases: Yki,AI325207,Yap65,Yap,Yorkie)

Yap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of stem cell maintenance GO:1902459 4 1.000
hippo signaling GO:0035329 11 1.000
positive regulation of glial cell proliferation GO:0060252 4 0.996
Fly
regulation of hippo signaling GO:0035330 1 0.991
regulation of stem cell maintenance GO:2000036 17 0.984
positive regulation of stem cell differentiation GO:2000738 23 0.984
regulation of stem cell differentiation GO:2000736 50 0.967
embryonic organ morphogenesis GO:0048562 276 0.961
stem cell proliferation GO:0072089 117 0.958
paraxial mesoderm development GO:0048339 18 0.949
stem cell maintenance GO:0019827 130 0.944
cilium morphogenesis GO:0060271 102 0.937
Mouse
lateral mesoderm development GO:0048368 13 0.932
regulation of smad protein import into nucleus GO:0060390 3 0.932
regulation of protein kinase activity GO:0045859 232 0.931
negative regulation of catenin import into nucleus GO:0035414 2 0.919
response to retinoic acid GO:0032526 56 0.899
regulation of intracellular protein transport GO:0033157 82 0.868
cellular response to retinoic acid GO:0071300 25 0.853
keratinocyte proliferation GO:0043616 21 0.840
morphogenesis of embryonic epithelium GO:0016331 159 0.828
multicellular organism growth GO:0035264 161 0.822
Mouse
regulation of keratinocyte proliferation GO:0010837 15 0.820
muscle tissue development GO:0060537 308 0.813
stem cell development GO:0048864 219 0.808
negative regulation of protein localization to nucleus GO:1900181 23 0.808
cellular response to lipid GO:0071396 145 0.807
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.806
embryonic heart tube development GO:0035050 65 0.796
cardiac muscle tissue development GO:0048738 130 0.783
cellular response to acid chemical GO:0071229 68 0.778
response to acid chemical GO:0001101 111 0.762
embryonic heart tube morphogenesis GO:0003143 51 0.754
regulation of protein targeting GO:1903533 61 0.751
epithelial tube formation GO:0072175 130 0.749
neural tube formation GO:0001841 108 0.744
urogenital system development GO:0001655 261 0.739
muscle system process GO:0003012 141 0.736
regulation of transferase activity GO:0051338 263 0.734
organ growth GO:0035265 117 0.732
regulation of stem cell proliferation GO:0072091 78 0.727
striated muscle tissue development GO:0014706 293 0.726
positive regulation of protein kinase activity GO:0045860 144 0.725
regulation of protein localization GO:0032880 231 0.724
mesenchyme development GO:0060485 152 0.724
negative regulation of phosphorus metabolic process GO:0010563 184 0.723
heart morphogenesis GO:0003007 178 0.710
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.704
negative regulation of intracellular signal transduction GO:1902532 167 0.697
neural tube closure GO:0001843 90 0.686
muscle adaptation GO:0043500 39 0.682
modification dependent macromolecule catabolic process GO:0043632 133 0.674
Mouse
regulation of skeletal muscle adaptation GO:0014733 12 0.672
cell fate commitment GO:0045165 210 0.672
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.667
extrinsic apoptotic signaling pathway GO:0097191 126 0.665
regulation of kinase activity GO:0043549 249 0.660
protein targeting GO:0006605 143 0.635
positive regulation of protein modification process GO:0031401 299 0.634
nucleocytoplasmic transport GO:0006913 139 0.625
negative regulation of protein phosphorylation GO:0001933 126 0.622
protein catabolic process GO:0030163 221 0.614
Mouse
regulation of protein import into nucleus GO:0042306 52 0.612
digestive system development GO:0055123 200 0.610
tube formation GO:0035148 140 0.607
regulation of fat cell differentiation GO:0045598 81 0.604
Mouse
cell fate specification GO:0001708 72 0.599
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.599
Mouse
cytoplasmic transport GO:0016482 234 0.598
notochord development GO:0030903 20 0.590
camera type eye development GO:0043010 266 0.586
keratinocyte differentiation GO:0030216 48 0.581
epithelial tube morphogenesis GO:0060562 303 0.580
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.574
positive regulation of transferase activity GO:0051347 167 0.566
positive regulation of cell development GO:0010720 237 0.564
negative regulation of transferase activity GO:0051348 85 0.562
positive regulation of growth GO:0045927 104 0.560
establishment of protein localization to organelle GO:0072594 118 0.549
regulation of apoptotic signaling pathway GO:2001233 197 0.549
regulation of intracellular transport GO:0032386 159 0.545
protein import into nucleus GO:0006606 95 0.545
nuclear transport GO:0051169 139 0.545
single organism nuclear import GO:1902593 95 0.533
protein import GO:0017038 101 0.531
negative regulation of fat cell differentiation GO:0045599 36 0.526
Mouse
negative regulation of protein modification process GO:0031400 163 0.526
ubiquitin dependent protein catabolic process GO:0006511 129 0.523
Mouse
fat cell differentiation GO:0045444 160 0.522
Mouse
positive regulation of kinase activity GO:0033674 155 0.520
limb development GO:0060173 166 0.507
renal system development GO:0072001 225 0.495
cardiac muscle cell development GO:0055013 39 0.494
morphogenesis of an epithelial sheet GO:0002011 27 0.494
Fly
somatic stem cell maintenance GO:0035019 47 0.492
protein localization to organelle GO:0033365 185 0.487
skin development GO:0043588 220 0.485
regulation of protein serine threonine kinase activity GO:0071900 157 0.484
regulation of epithelial cell proliferation GO:0050678 141 0.484
regulation of mapk cascade GO:0043408 248 0.481
kidney morphogenesis GO:0060993 83 0.480
Mouse
cardiocyte differentiation GO:0035051 87 0.465
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.461
stem cell differentiation GO:0048863 268 0.460
retinal blood vessel morphogenesis GO:0061304 3 0.456
neural tube development GO:0021915 160 0.449
wnt signaling pathway GO:0016055 188 0.448
regulation of cellular ketone metabolic process GO:0010565 66 0.448
mesoderm development GO:0007498 100 0.444
negative regulation of intracellular protein transport GO:0090317 27 0.437
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.435
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.435
ossification GO:0001503 216 0.426
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.419
transition between fast and slow fiber GO:0014883 9 0.419
negative regulation of stem cell differentiation GO:2000737 14 0.418
regulation of neuron differentiation GO:0045664 281 0.413
negative regulation of cellular protein metabolic process GO:0032269 247 0.412
nephron development GO:0072006 109 0.405
negative regulation of kinase activity GO:0033673 81 0.404
tube closure GO:0060606 91 0.402
epidermis development GO:0008544 187 0.400
regulation of protein localization to nucleus GO:1900180 60 0.397
kidney development GO:0001822 213 0.393
regulation of organ growth GO:0046620 61 0.392
apoptotic signaling pathway GO:0097190 306 0.392
regulation of nucleocytoplasmic transport GO:0046822 73 0.388
response to radiation GO:0009314 165 0.386
Human
regulation of cytoplasmic transport GO:1903649 112 0.385
macromolecule catabolic process GO:0009057 281 0.385
Mouse
blood vessel morphogenesis GO:0048514 285 0.383
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.382
trophectodermal cell differentiation GO:0001829 21 0.368
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.364
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.360
regulation of gliogenesis GO:0014013 50 0.355
Fly
nuclear import GO:0051170 95 0.348
regulation of muscle system process GO:0090257 80 0.346
protein modification by small protein conjugation GO:0032446 187 0.339
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.338
cellular amine metabolic process GO:0044106 44 0.330
amine metabolic process GO:0009308 45 0.327
regulation of system process GO:0044057 200 0.326
regulation of catenin import into nucleus GO:0035412 5 0.320
response to transforming growth factor beta GO:0071559 88 0.318
negative regulation of phosphorylation GO:0042326 166 0.316
leukocyte differentiation GO:0002521 342 0.313
proteasomal protein catabolic process GO:0010498 98 0.311
Mouse
t cell activation GO:0042110 289 0.310
intracellular protein transport GO:0006886 204 0.309
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.301
Mouse
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.301
negative regulation of cytoplasmic transport GO:1903650 29 0.300
positive regulation of wnt signaling pathway GO:0030177 45 0.298
regulation of cellular amino acid metabolic process GO:0006521 5 0.297
regulation of angiogenesis GO:0045765 81 0.297
mesenchymal cell differentiation GO:0048762 107 0.296
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.293
Mouse
regulation of cell cycle GO:0051726 281 0.287
myeloid cell differentiation GO:0030099 233 0.286
protein localization to nucleus GO:0034504 121 0.276
lens development in camera type eye GO:0002088 62 0.270
cardiac cell development GO:0055006 41 0.269
blastocyst development GO:0001824 80 0.262
negative regulation of intracellular transport GO:0032387 38 0.261
establishment or maintenance of cell polarity GO:0007163 86 0.258
cell adhesion GO:0007155 329 0.256
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.253
limb morphogenesis GO:0035108 149 0.251
regulation of glial cell proliferation GO:0060251 8 0.251
Fly
cellular ketone metabolic process GO:0042180 84 0.249
synaptic transmission GO:0007268 329 0.245
appendage morphogenesis GO:0035107 149 0.241
peptidyl tyrosine modification GO:0018212 145 0.238
protein modification by small protein conjugation or removal GO:0070647 207 0.237
Mouse
negative regulation of molecular function GO:0044092 258 0.234
appendage development GO:0048736 166 0.232
cellular response to growth factor stimulus GO:0071363 197 0.231
sensory organ morphogenesis GO:0090596 242 0.230
branching morphogenesis of an epithelial tube GO:0048754 159 0.227
nephron tubule epithelial cell differentiation GO:0072160 11 0.227
metanephric tubule development GO:0072170 18 0.226
primary neural tube formation GO:0014020 95 0.226
morphogenesis of a polarized epithelium GO:0001738 37 0.226
metanephros development GO:0001656 79 0.224
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.223
wound healing GO:0042060 157 0.220
glial cell proliferation GO:0014009 10 0.219
Fly
regulation of cellular response to stress GO:0080135 159 0.217
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.212
muscle cell differentiation GO:0042692 261 0.211
negative regulation of protein metabolic process GO:0051248 282 0.210
bmp signaling pathway GO:0030509 93 0.207
skeletal muscle adaptation GO:0043501 16 0.207
negative regulation of cell proliferation GO:0008285 296 0.207
cellular response to gamma radiation GO:0071480 4 0.205
Human
peptidyl tyrosine phosphorylation GO:0018108 143 0.203
regionalization GO:0003002 337 0.201
cell differentiation involved in metanephros development GO:0072202 12 0.199
peptidyl amino acid modification GO:0018193 336 0.198
establishment of cell polarity involved in ameboidal cell migration GO:0003365 2 0.196
positive regulation of protein phosphorylation GO:0001934 242 0.194
embryonic skeletal system development GO:0048706 120 0.190
hair cycle GO:0042633 90 0.189
mesenchymal cell development GO:0014031 93 0.187
multi multicellular organism process GO:0044706 109 0.187
response to ionizing radiation GO:0010212 42 0.187
Human
purine ribonucleotide metabolic process GO:0009150 290 0.184
canonical wnt signaling pathway GO:0060070 130 0.183
neural precursor cell proliferation GO:0061351 121 0.181
sensory perception of mechanical stimulus GO:0050954 107 0.180
morphogenesis of a branching epithelium GO:0061138 193 0.180
regulation of establishment of protein localization GO:0070201 181 0.179
positive regulation of gliogenesis GO:0014015 27 0.178
Fly
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.178
positive regulation of apoptotic process GO:0043065 217 0.171
gland development GO:0048732 330 0.169
hair follicle development GO:0001942 85 0.166
epithelium migration GO:0090132 63 0.166
Fly
metanephric nephron tubule epithelial cell differentiation GO:0072257 5 0.165
regulation of kidney development GO:0090183 40 0.164
smooth muscle tissue development GO:0048745 22 0.161
formation of radial glial scaffolds GO:0021943 4 0.160
regulation of metanephros development GO:0072215 15 0.159
osteoclast differentiation GO:0030316 62 0.157
cardiac septum development GO:0003279 59 0.153
epithelial cell differentiation involved in kidney development GO:0035850 23 0.151
catenin import into nucleus GO:0035411 6 0.149
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.149
compound eye development GO:0048749 1 0.149
regulation of jnk cascade GO:0046328 62 0.148
negative regulation of protein import into nucleus GO:0042308 21 0.147
regulation of protein transport GO:0051223 163 0.145
regulation of neuron projection development GO:0010975 169 0.144
oocyte axis specification GO:0007309 2 0.143
positive regulation of programmed cell death GO:0043068 218 0.142
regulation of hydrolase activity GO:0051336 246 0.140
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.140
negative regulation of nervous system development GO:0051961 156 0.139
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.138
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.138
endocrine system development GO:0035270 98 0.138
cell cell junction organization GO:0045216 72 0.136
embryonic appendage morphogenesis GO:0035113 126 0.136
negative regulation of organ growth GO:0046621 17 0.135
neuroblast differentiation GO:0014016 2 0.135
nucleotide metabolic process GO:0009117 332 0.135
synapse organization GO:0050808 125 0.134
regulation of osteoblast differentiation GO:0045667 67 0.131
cellular component assembly involved in morphogenesis GO:0010927 139 0.131
regulation of endothelial cell chemotaxis GO:2001026 1 0.130
actin cytoskeleton organization GO:0030036 220 0.130
regulation of myeloid cell differentiation GO:0045637 96 0.129
positive regulation of organ growth GO:0046622 29 0.129
negative regulation of cell cycle GO:0045786 123 0.129
purine containing compound metabolic process GO:0072521 311 0.128
blastocyst formation GO:0001825 33 0.127
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.125
hepaticobiliary system development GO:0061008 67 0.125
skeletal system development GO:0001501 356 0.124
Zebrafish
striated muscle adaptation GO:0014888 26 0.123
adherens junction organization GO:0034332 28 0.123
somite development GO:0061053 81 0.123
muscle cell development GO:0055001 133 0.122
ribonucleotide metabolic process GO:0009259 291 0.121
retina vasculature development in camera type eye GO:0061298 17 0.120
embryonic limb morphogenesis GO:0030326 126 0.119
embryonic epithelial tube formation GO:0001838 130 0.118
regulation of muscle adaptation GO:0043502 31 0.117
cell junction assembly GO:0034329 52 0.116
jnk cascade GO:0007254 72 0.116
response to hypoxia GO:0001666 58 0.115
regulation of cell migration GO:0030334 219 0.113
regulation of cell cycle process GO:0010564 160 0.113
regulation of cellular catabolic process GO:0031329 242 0.113
negative regulation of epithelial cell proliferation GO:0050680 64 0.112
inflammatory response GO:0006954 244 0.112
cell growth GO:0016049 130 0.112
myeloid leukocyte differentiation GO:0002573 119 0.112
cellular amino acid metabolic process GO:0006520 103 0.111
regulation of stress activated mapk cascade GO:0032872 69 0.110
bone morphogenesis GO:0060349 78 0.110
regulation of cell motility GO:2000145 236 0.110
glomerulus development GO:0032835 40 0.108
Mouse
regulation of neuron death GO:1901214 134 0.108
regulation of homeostatic process GO:0032844 182 0.107
angiogenesis GO:0001525 201 0.106
osteoblast development GO:0002076 17 0.105
protein ubiquitination GO:0016567 171 0.105
Mouse
transmembrane transport GO:0055085 412 0.105
epithelial cell development GO:0002064 159 0.105
Fly
regulation of cellular component size GO:0032535 121 0.105
smad protein import into nucleus GO:0007184 6 0.103
positive regulation of stem cell proliferation GO:2000648 59 0.101
metanephric epithelium development GO:0072207 21 0.101
respiratory tube development GO:0030323 167 0.100
stress activated protein kinase signaling cascade GO:0031098 81 0.100
gliogenesis GO:0042063 141 0.099
Fly
negative regulation of wnt signaling pathway GO:0030178 73 0.098
negative regulation of myeloid cell differentiation GO:0045638 38 0.098
regulation of protein deacetylation GO:0090311 17 0.098
metanephric nephron tubule development GO:0072234 16 0.097
regulation of astrocyte differentiation GO:0048710 20 0.096
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.095
cell chemotaxis GO:0060326 81 0.095
cell division GO:0051301 120 0.093
cell matrix adhesion GO:0007160 68 0.092
morphogenesis of a branching structure GO:0001763 203 0.092
synapse assembly GO:0007416 56 0.091
cell maturation GO:0048469 127 0.091
negative regulation of bmp signaling pathway GO:0030514 35 0.091
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.090
adherens junction assembly GO:0034333 22 0.090
osteoblast fate commitment GO:0002051 4 0.088
organelle fission GO:0048285 170 0.088
stem cell division GO:0017145 30 0.088
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.087
focal adhesion assembly GO:0048041 19 0.087
regulation of anatomical structure size GO:0090066 178 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.086
negative regulation of map kinase activity GO:0043407 34 0.086
positive regulation of map kinase activity GO:0043406 84 0.086
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.086
meiotic cell cycle GO:0051321 122 0.086
monocyte differentiation GO:0030224 9 0.086
ear morphogenesis GO:0042471 118 0.085
regulation of bmp signaling pathway GO:0030510 60 0.085
ventricular septum morphogenesis GO:0060412 27 0.085
negative regulation of ossification GO:0030279 49 0.084
endocardial cell differentiation GO:0060956 4 0.084
regulation of organ morphogenesis GO:2000027 144 0.083
molting cycle GO:0042303 90 0.083
digestive tract morphogenesis GO:0048546 147 0.083
mesodermal cell migration GO:0008078 4 0.083
regulation of cellular response to growth factor stimulus GO:0090287 82 0.082
regulation of chromatin modification GO:1903308 57 0.081
positive regulation of cell projection organization GO:0031346 95 0.081
development of primary sexual characteristics GO:0045137 143 0.081
nucleoside catabolic process GO:0009164 206 0.081
regulation of neuroblast proliferation GO:1902692 27 0.080
ribonucleoside catabolic process GO:0042454 206 0.080
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.079
positive regulation of cell motility GO:2000147 116 0.079
response to growth factor GO:0070848 198 0.079
cardiac septum morphogenesis GO:0060411 46 0.078
negative regulation of dna replication GO:0008156 4 0.078
p38mapk cascade GO:0038066 4 0.078
regulation of body fluid levels GO:0050878 162 0.078
purine nucleotide catabolic process GO:0006195 211 0.078
cardiac muscle tissue morphogenesis GO:0055008 44 0.076
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.076
cell differentiation involved in kidney development GO:0061005 33 0.076
regulation of canonical wnt signaling pathway GO:0060828 82 0.075
nuclear division GO:0000280 158 0.075
negative regulation of granulocyte differentiation GO:0030853 3 0.074
anatomical structure homeostasis GO:0060249 145 0.074
epithelial cell migration GO:0010631 63 0.074
Fly
transmission of nerve impulse GO:0019226 76 0.074
covalent chromatin modification GO:0016569 163 0.074
ribonucleoside triphosphate metabolic process GO:0009199 220 0.073
somitogenesis GO:0001756 69 0.073
cardiac endothelial cell differentiation GO:0003348 4 0.073
organophosphate catabolic process GO:0046434 232 0.072
action potential GO:0001508 78 0.072
digestive tract development GO:0048565 190 0.072
response to oxygen levels GO:0070482 62 0.071
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.071
neuron apoptotic process GO:0051402 142 0.071
positive regulation of cellular amine metabolic process GO:0033240 5 0.071
neuroblast proliferation GO:0007405 49 0.070
cellular nitrogen compound catabolic process GO:0044270 280 0.070
regulation of histone modification GO:0031056 56 0.070
cell cycle g1 s phase transition GO:0044843 57 0.069
negative regulation of mitotic cell cycle GO:0045930 58 0.069
epithelial cell morphogenesis GO:0003382 41 0.069
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.069
renal tubule morphogenesis GO:0061333 72 0.069
muscle contraction GO:0006936 101 0.069
cell junction organization GO:0034330 77 0.069
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.068
mitotic cell cycle GO:0000278 195 0.068
germ line stem cell division GO:0042078 2 0.067
negative regulation of protein processing GO:0010955 79 0.067
mesenchymal cell proliferation GO:0010463 44 0.067
actomyosin structure organization GO:0031032 56 0.067
embryonic digestive tract development GO:0048566 27 0.066
epithelial to mesenchymal transition GO:0001837 47 0.066
asymmetric neuroblast division GO:0055059 1 0.066
gonad development GO:0008406 141 0.066
positive regulation of epithelial cell proliferation GO:0050679 68 0.065
b cell activation GO:0042113 161 0.065
spermatid development GO:0007286 108 0.065
regulation of map kinase activity GO:0043405 120 0.065
ribose phosphate metabolic process GO:0019693 291 0.065
cellular lipid metabolic process GO:0044255 323 0.065
regulation of membrane potential GO:0042391 192 0.064
positive regulation of apoptotic signaling pathway GO:2001235 95 0.063
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.063
actin filament based movement GO:0030048 23 0.063
engulfment of apoptotic cell GO:0043652 3 0.062
stress activated mapk cascade GO:0051403 80 0.061
rhythmic process GO:0048511 174 0.060
divalent inorganic cation transport GO:0072511 178 0.059
regulation of erk1 and erk2 cascade GO:0070372 71 0.059
chondrocyte development GO:0002063 24 0.059
negative regulation of cellular amine metabolic process GO:0033239 1 0.058
cation transmembrane transport GO:0098655 266 0.058
regulation of peptidase activity GO:0052547 96 0.058
multicellular organismal homeostasis GO:0048871 164 0.058
mammary gland epithelium development GO:0061180 65 0.058
negative regulation of glial cell proliferation GO:0060253 4 0.058
positive regulation of neuron death GO:1901216 28 0.058
regulation of cellular component biogenesis GO:0044087 181 0.058
oocyte differentiation GO:0009994 35 0.058
regulation of purine nucleotide metabolic process GO:1900542 169 0.057
erythrocyte differentiation GO:0030218 88 0.057
ras protein signal transduction GO:0007265 77 0.057
sensory perception GO:0007600 245 0.057
negative regulation of osteoblast differentiation GO:0045668 30 0.056
skeletal system morphogenesis GO:0048705 203 0.056
response to decreased oxygen levels GO:0036293 59 0.056
positive regulation of keratinocyte proliferation GO:0010838 4 0.056
cell substrate adhesion GO:0031589 130 0.056
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.056
kidney mesenchyme morphogenesis GO:0072131 4 0.056
male gamete generation GO:0048232 285 0.055
endothelial cell migration GO:0043542 44 0.055
neuronal action potential GO:0019228 54 0.054
macrophage differentiation GO:0030225 20 0.054
positive regulation of cell death GO:0010942 224 0.054
spermatogenesis GO:0007283 284 0.054
cardiac muscle cell differentiation GO:0055007 69 0.054
oocyte construction GO:0007308 2 0.053
endochondral bone morphogenesis GO:0060350 50 0.053
heart formation GO:0060914 16 0.053
regulation of ossification GO:0030278 112 0.053
epithelial cell proliferation GO:0050673 174 0.053
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.053
response to uv GO:0009411 44 0.052
formation of organ boundary GO:0010160 1 0.052
nucleobase containing small molecule metabolic process GO:0055086 352 0.052
gastrulation GO:0007369 116 0.051
ear development GO:0043583 200 0.051
negative regulation of hydrolase activity GO:0051346 71 0.051
reactive nitrogen species metabolic process GO:2001057 0 0.051
cation homeostasis GO:0055080 212 0.051
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.050
Fly
purine nucleotide metabolic process GO:0006163 302 0.050
respiratory system development GO:0060541 190 0.050
axonogenesis GO:0007409 274 0.050
negative regulation of growth GO:0045926 99 0.050
activation of mapk activity GO:0000187 59 0.049
nucleoside triphosphate metabolic process GO:0009141 230 0.049
chromatin organization GO:0006325 206 0.049
septum primum development GO:0003284 4 0.049
positive regulation of protein import into nucleus GO:0042307 26 0.049
salivary gland development GO:0007431 37 0.049
regulation of hormone levels GO:0010817 211 0.049
t cell differentiation GO:0030217 174 0.049
regulation of transcription factor import into nucleus GO:0042990 24 0.049
negative regulation of cell cycle process GO:0010948 69 0.049
mitochondrion degradation GO:0000422 3 0.048
positive regulation of smad protein import into nucleus GO:0060391 2 0.048
positive regulation of intracellular protein transport GO:0090316 42 0.048
release of cytochrome c from mitochondria GO:0001836 23 0.048
positive regulation of cell cycle GO:0045787 92 0.048
odontogenesis GO:0042476 78 0.048
regulation of neuron apoptotic process GO:0043523 122 0.048
positive regulation of macroautophagy GO:0016239 3 0.047
germ cell development GO:0007281 185 0.047
Fly
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.047
connective tissue development GO:0061448 179 0.047
Zebrafish
regulation of protein maturation GO:1903317 96 0.047
membrane organization GO:0061024 245 0.047
single organismal cell cell adhesion GO:0016337 131 0.047
dna replication GO:0006260 52 0.047
b cell differentiation GO:0030183 78 0.047
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.046
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.046
inner ear morphogenesis GO:0042472 101 0.046
purine nucleoside metabolic process GO:0042278 241 0.045
cellular response to dna damage stimulus GO:0006974 207 0.045
Human

Yap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.237
disease of cellular proliferation DOID:14566 0 0.237
disease of anatomical entity DOID:7 0 0.175
musculoskeletal system disease DOID:17 0 0.175
immune system cancer DOID:0060083 0 0.165
organ system cancer DOID:0050686 0 0.165
hematologic cancer DOID:2531 0 0.132
sensory system disease DOID:0050155 0 0.073
eye and adnexa disease DOID:1492 0 0.073
nervous system disease DOID:863 0 0.073
eye disease DOID:5614 0 0.073
connective tissue disease DOID:65 0 0.049
cardiovascular system disease DOID:1287 0 0.048
myeloid leukemia DOID:8692 0 0.047
leukemia DOID:1240 0 0.047