|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.983
|
Fly |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.888
|
Fly |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.884
|
Fly |
|
|
regulation of epidermal cell division
|
GO:0010482 |
3 |
0.882
|
Mouse |
|
|
inclusion body assembly
|
GO:0070841 |
3 |
0.839
|
Yeast |
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.809
|
Fly |
|
|
protein targeting
|
GO:0006605 |
143 |
0.805
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.801
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.788
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.768
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.747
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.746
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.735
|
Yeast |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.721
|
Yeast |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.721
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.704
|
Yeast Mouse Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.700
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.686
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.682
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.673
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.652
|
Yeast Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.651
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.645
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
2 |
0.631
|
Mouse |
|
|
keratinocyte development
|
GO:0003334 |
10 |
0.630
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.606
|
Fly |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.602
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.599
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.575
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.575
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.571
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.570
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.566
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.557
|
Fly |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.548
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.541
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.523
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.520
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.519
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.511
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.510
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.506
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.499
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.492
|
Fly |
|
|
autophagy
|
GO:0006914 |
45 |
0.492
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.491
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.489
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.489
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.487
|
Yeast Worm Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.482
|
Yeast Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.478
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.473
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.471
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.468
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.463
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.462
|
Yeast Mouse Worm |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.460
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.447
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.432
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.432
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.431
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.426
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.425
|
Yeast Mouse Worm |
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.410
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.405
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.396
|
Human |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.393
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.391
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.388
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.387
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.387
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.384
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.381
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
11 |
0.347
|
Mouse |
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.345
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.345
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.344
|
Yeast |
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.343
|
Fly |
|
|
protein heterooligomerization
|
GO:0051291 |
14 |
0.339
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.339
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.336
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.335
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.334
|
Mouse |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.333
|
Yeast |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.333
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.333
|
Yeast |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.333
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.331
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.329
|
|
|
|
negative regulation of peroxidase activity
|
GO:2000469 |
1 |
0.325
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.325
|
Worm |
|
|
zygote asymmetric cell division
|
GO:0010070 |
2 |
0.324
|
Worm |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.323
|
Worm Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.322
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.322
|
Yeast |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.312
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.310
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.308
|
Mouse |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.308
|
|
|
|
aggresome assembly
|
GO:0070842 |
2 |
0.307
|
Yeast |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.305
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.305
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.304
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.303
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.302
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.297
|
Fly |
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
3 |
0.297
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.294
|
Fly |
|
|
vesicle localization
|
GO:0051648 |
86 |
0.294
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.292
|
Worm |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.287
|
Mouse |
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
13 |
0.280
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.277
|
Worm |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.276
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.276
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.273
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.272
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.271
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.267
|
Worm Fly |
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.257
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.255
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.253
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.252
|
Yeast Mouse |
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.250
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.246
|
Yeast |
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.243
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.236
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.234
|
Fly |
|
|
oogenesis
|
GO:0048477 |
56 |
0.234
|
Fly |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.230
|
Mouse |
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.220
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.218
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.217
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.216
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.215
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.213
|
|
|
|
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051439 |
1 |
0.212
|
Yeast |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.211
|
Worm |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.207
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.206
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.195
|
|
|
|
epidermal cell division
|
GO:0010481 |
3 |
0.192
|
Mouse |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.188
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.186
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.185
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.185
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.184
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.184
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.183
|
Worm Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.182
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.181
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.181
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.181
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.180
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.179
|
Mouse |
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
13 |
0.175
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.175
|
Mouse |
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.174
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.174
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.173
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.172
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.172
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.172
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.172
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.172
|
Fly |
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.167
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.167
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.166
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.165
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.164
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.163
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.163
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.163
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.161
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.161
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.161
|
Yeast Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.161
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.161
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.160
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.160
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.160
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
3 |
0.159
|
Yeast |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.159
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.159
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.158
|
Yeast |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.158
|
Mouse |
|
|
protein targeting to mitochondrion
|
GO:0006626 |
6 |
0.158
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.158
|
Yeast Worm |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.154
|
Human |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.153
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.152
|
Mouse |
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.152
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.151
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.151
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.149
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.149
|
Yeast |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.148
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.147
|
Yeast |
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.147
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.146
|
Worm Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.146
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.146
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.144
|
|
|
|
protein stabilization
|
GO:0050821 |
25 |
0.144
|
Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.143
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.142
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.142
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.141
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.140
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.139
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.138
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.137
|
Yeast |
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.137
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.137
|
Fly |
|
|
dendrite development
|
GO:0016358 |
115 |
0.137
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.137
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.134
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.134
|
Mouse |
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.133
|
Mouse |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.132
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.130
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.129
|
Mouse |
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.128
|
Yeast |
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.128
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.128
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.128
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.128
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.127
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.125
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.124
|
Yeast |
|
|
terminal button organization
|
GO:0072553 |
3 |
0.122
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.121
|
Yeast Mouse |
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.121
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.120
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.120
|
Yeast |
|
|
single fertilization
|
GO:0007338 |
82 |
0.119
|
Worm |
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.118
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.118
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.118
|
Worm |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.117
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.117
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.116
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
80 |
0.116
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.115
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.114
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.113
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.113
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.112
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.112
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.111
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.111
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.111
|
Mouse |
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.109
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.109
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
18 |
0.108
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.107
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.106
|
Yeast |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
7 |
0.106
|
Yeast |
|
|
gluconeogenesis
|
GO:0006094 |
39 |
0.105
|
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.105
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.105
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.103
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.103
|
Fly |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.102
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.102
|
Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.101
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.101
|
Mouse |
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.101
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.101
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.101
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.100
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.100
|
Yeast Worm |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.100
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.099
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.099
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.099
|
Yeast |
|
|
learning
|
GO:0007612 |
98 |
0.099
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.099
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.098
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.098
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.097
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.097
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.096
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.096
|
Yeast Worm |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.096
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.095
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.095
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.095
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.095
|
Yeast |
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.094
|
Worm |
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.094
|
Yeast |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.094
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.093
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.092
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.092
|
Worm |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.091
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.091
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.091
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.090
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.090
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.089
|
|
|
|
intermediate filament based process
|
GO:0045103 |
27 |
0.089
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.089
|
Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.089
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.089
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.086
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.085
|
|
|
|
negative regulation of mitochondrion organization
|
GO:0010823 |
9 |
0.085
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.085
|
|
|
|
regulation of transposition
|
GO:0010528 |
2 |
0.085
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.085
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.084
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.083
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.082
|
Yeast |
|
|
action potential
|
GO:0001508 |
78 |
0.082
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.082
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.081
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.081
|
Yeast |
|
|
protein export from nucleus
|
GO:0006611 |
20 |
0.081
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.080
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.079
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.079
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.079
|
Worm |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.079
|
Yeast |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.078
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.078
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.078
|
Yeast |
|
|
cell maturation
|
GO:0048469 |
127 |
0.077
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.077
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.077
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.077
|
Mouse |
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.077
|
|
|
|
regulation of terminal button organization
|
GO:2000331 |
1 |
0.077
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.076
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.076
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.076
|
Worm |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.076
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.076
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.075
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.075
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.075
|
Yeast |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.075
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.074
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.074
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.073
|
Mouse |
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.073
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
11 |
0.073
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.073
|
Yeast |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.073
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
19 |
0.073
|
Yeast |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.072
|
Yeast |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.071
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.071
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.071
|
|
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.071
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.071
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.070
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.070
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.069
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.069
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
11 |
0.068
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.068
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.067
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.067
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.067
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.067
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.067
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.067
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.067
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.067
|
|
|
|
regulation of peroxidase activity
|
GO:2000468 |
1 |
0.066
|
|
|
|
positive regulation of autophagy
|
GO:0010508 |
9 |
0.066
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.066
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.065
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.065
|
Yeast |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.065
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.065
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.064
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.064
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.064
|
Yeast |
|
|
muscle cell development
|
GO:0055001 |
133 |
0.064
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.064
|
|
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.064
|
Worm |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.064
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.063
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.063
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.063
|
Yeast Worm |
|
|
cell fate determination
|
GO:0001709 |
32 |
0.063
|
Worm Fly |
|
|
negative regulation of keratinocyte proliferation
|
GO:0010839 |
7 |
0.063
|
Mouse |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.063
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.062
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.062
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.062
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
15 |
0.062
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.062
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.061
|
|
|
|
olfactory bulb development
|
GO:0021772 |
30 |
0.061
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.061
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.060
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.060
|
|
|
|
establishment of melanosome localization
|
GO:0032401 |
11 |
0.059
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.059
|
|
|
|
organelle disassembly
|
GO:1903008 |
2 |
0.058
|
|
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.058
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.058
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.058
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.058
|
|
|
|
cellular response to monoamine stimulus
|
GO:0071868 |
3 |
0.058
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.057
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.057
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.057
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.057
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.057
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.057
|
Fly |
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.057
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
9 |
0.057
|
Yeast |
|
|
cellular response to ammonium ion
|
GO:0071242 |
2 |
0.056
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
11 |
0.056
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.056
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.056
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.056
|
Yeast |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.055
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.055
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.055
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.055
|
|
|
|
positive regulation of epidermal cell differentiation
|
GO:0045606 |
6 |
0.055
|
Mouse |
|
|
membrane fusion
|
GO:0061025 |
38 |
0.055
|
|
|
|
phospholipid biosynthetic process
|
GO:0008654 |
36 |
0.055
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.054
|
|
|
|
negative regulation of nucleoside metabolic process
|
GO:0045978 |
11 |
0.054
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.054
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.054
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
4 |
0.053
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.053
|
|
|
|
negative regulation of purine nucleotide catabolic process
|
GO:0033122 |
9 |
0.053
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.052
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.052
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.052
|
|
|
|
mitochondrion localization
|
GO:0051646 |
9 |
0.052
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.052
|
|
|
|
centrosome separation
|
GO:0051299 |
4 |
0.052
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.052
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.052
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.051
|
Mouse |
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.051
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.051
|
|
|
|
regulation of dendritic spine development
|
GO:0060998 |
22 |
0.051
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.051
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.051
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.051
|
|
|
|
organelle fusion
|
GO:0048284 |
28 |
0.051
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.050
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.050
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.050
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.050
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.050
|
|
|
|
protein refolding
|
GO:0042026 |
1 |
0.049
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.049
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.049
|
Mouse |
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.049
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.049
|
|
|
|
regulation of dendritic spine morphogenesis
|
GO:0061001 |
17 |
0.049
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.049
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.048
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.048
|
Yeast Mouse |
|
|
olfactory lobe development
|
GO:0021988 |
32 |
0.048
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.048
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.048
|
Yeast |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.047
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.047
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.047
|
Mouse |
|
|
tor signaling
|
GO:0031929 |
21 |
0.047
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.047
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.047
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.047
|
Yeast |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.046
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.046
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.046
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.046
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.046
|
|
|
|
nucleus localization
|
GO:0051647 |
20 |
0.045
|
Worm |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.045
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.045
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.044
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.044
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.044
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.044
|
Yeast |
