|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.776
|
Yeast Worm Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.634
|
Worm Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.427
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.390
|
Yeast |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.386
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.367
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.338
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.335
|
Yeast |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.331
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.319
|
Fly |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.317
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.308
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.302
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.294
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.282
|
Yeast Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.275
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.273
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.265
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.264
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.258
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.257
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.250
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.249
|
Yeast Fly |
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.247
|
Fly |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.246
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.233
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.226
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.217
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.216
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.214
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.214
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.205
|
Yeast Worm |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.202
|
Mouse |
|
|
organelle localization
|
GO:0051640 |
179 |
0.186
|
Worm |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.180
|
|
|
|
glucose catabolic process
|
GO:0006007 |
3 |
0.177
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.172
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.172
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.171
|
Yeast |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.170
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.169
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.167
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.165
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.164
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.164
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.163
|
|
|
|
regulation of epidermal cell division
|
GO:0010482 |
3 |
0.161
|
Mouse |
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
20 |
0.158
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.156
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.154
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.150
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.150
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.145
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.144
|
Mouse |
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.143
|
Yeast |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.143
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.142
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.141
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.139
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.139
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.139
|
|
|
|
hexose catabolic process
|
GO:0019320 |
3 |
0.138
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.138
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.131
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.131
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.130
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.130
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.130
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.127
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.126
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.123
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.123
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.122
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.120
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.120
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.118
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.117
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.116
|
|
|
|
dna templated transcription termination
|
GO:0006353 |
4 |
0.115
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.115
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.114
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.113
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.111
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.107
|
Yeast Mouse Worm |
|
|
cell division
|
GO:0051301 |
120 |
0.104
|
Yeast Mouse Worm |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.104
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.103
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.102
|
|
|
|
keratinocyte development
|
GO:0003334 |
10 |
0.102
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.101
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.101
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.100
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.099
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.099
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.098
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.098
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.095
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.094
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.093
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.092
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.092
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.091
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.091
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.090
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.090
|
Yeast |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.090
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.089
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.089
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.087
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.086
|
Mouse |
|
|
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051439 |
1 |
0.085
|
Yeast |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.084
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.084
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.084
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.083
|
Worm Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.082
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.082
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.082
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.081
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.081
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.081
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.080
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.080
|
Yeast |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.078
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.076
|
Fly |
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.075
|
Worm |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.074
|
|
|
|
aggresome assembly
|
GO:0070842 |
2 |
0.073
|
Yeast |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.073
|
Yeast |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.073
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.071
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.070
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.069
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.069
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.069
|
|
|
|
positive regulation of receptor biosynthetic process
|
GO:0010870 |
1 |
0.069
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.068
|
Yeast |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.067
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.067
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.067
|
Yeast Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.067
|
Yeast |
|
|
mrna splicing via spliceosome
|
GO:0000398 |
43 |
0.065
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.065
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.065
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.064
|
Yeast Worm |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.064
|
|
|
|
killing of cells of other organism
|
GO:0031640 |
13 |
0.064
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.064
|
Yeast Mouse |
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.063
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.063
|
Yeast |
|
|
centriole assembly
|
GO:0098534 |
6 |
0.063
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.063
|
Yeast |
|
|
blood circulation
|
GO:0008015 |
195 |
0.062
|
|
|
|
rna splicing
|
GO:0008380 |
54 |
0.061
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.061
|
Mouse |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.061
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.061
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.060
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.060
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.060
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.059
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.059
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.059
|
Yeast |
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
20 |
0.059
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.058
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.057
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.056
|
Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.056
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.056
|
Yeast |
|
|
visual perception
|
GO:0007601 |
52 |
0.056
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.055
|
Yeast |
|
|
cellular response to hexose stimulus
|
GO:0071331 |
47 |
0.055
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.055
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.054
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.054
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.054
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.054
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.053
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.053
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.053
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.052
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.052
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.052
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.051
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.051
|
|
|
|
disruption of cells of other organism
|
GO:0044364 |
13 |
0.051
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.051
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.050
|
Worm |
|
|
protein processing
|
GO:0016485 |
163 |
0.050
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.050
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
43 |
0.050
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.049
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.049
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.049
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.049
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.049
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.049
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.049
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.049
|
Fly |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.049
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.048
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.048
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.048
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.048
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.048
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.047
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.047
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.047
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.047
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.046
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.046
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.046
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.046
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.045
|
|
|
|
spindle organization
|
GO:0007051 |
28 |
0.045
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.045
|
Worm |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.045
|
Yeast |
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
2 |
0.045
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.045
|
Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.045
|
Mouse |
|
|
epidermal cell division
|
GO:0010481 |
3 |
0.045
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.045
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.044
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.044
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.044
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.044
|
|
|
|
response to calcium ion
|
GO:0051592 |
20 |
0.044
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.043
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.042
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.042
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.042
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.042
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.042
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.042
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.042
|
Yeast |
|
|
cell growth
|
GO:0016049 |
130 |
0.041
|
Yeast Mouse |
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.041
|
|
|
|
disruption of cells of other organism involved in symbiotic interaction
|
GO:0051818 |
13 |
0.041
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.041
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.041
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.041
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.041
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.040
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.040
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.040
|
|
|
|
regulation of killing of cells of other organism
|
GO:0051709 |
4 |
0.040
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.040
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.040
|
Yeast |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.040
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.040
|
Yeast Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.039
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.039
|
Mouse |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.039
|
Yeast |
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.039
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.038
|
Mouse |
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.038
|
Yeast |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.038
|
Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.038
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.038
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.037
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.037
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.037
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.037
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.037
|
Mouse |
|
|
keratinization
|
GO:0031424 |
9 |
0.037
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.037
|
|
|
|
axon cargo transport
|
GO:0008088 |
33 |
0.037
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.036
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.036
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.036
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.035
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.035
|
Worm |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.035
|
Yeast |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.035
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.035
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.035
|
Fly |
|
|
pigmentation
|
GO:0043473 |
71 |
0.035
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.034
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.034
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.034
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
20 |
0.034
|
Yeast |
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.033
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.033
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.033
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.033
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.033
|
|
|
|
receptor biosynthetic process
|
GO:0032800 |
3 |
0.033
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.032
|
Fly |
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.032
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.032
|
Yeast |
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.031
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.031
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.031
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.031
|
Worm |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.031
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.031
|
Mouse |
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.031
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.031
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.031
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.030
|
Mouse |
|
|
hippocampus development
|
GO:0021766 |
52 |
0.030
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.030
|
|
|
|
regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061178 |
31 |
0.030
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.030
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.030
|
Mouse |
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.030
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.030
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.030
|
Yeast Worm |
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.030
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.030
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.030
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.030
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.029
|
Yeast |
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.029
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.029
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.029
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.029
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.028
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
19 |
0.028
|
Yeast |
|
|
b cell activation
|
GO:0042113 |
161 |
0.028
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.028
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.028
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.028
|
Fly |
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.028
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.027
|
Human |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.027
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.027
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.027
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.027
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.027
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.027
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.027
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.027
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
30 |
0.027
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.027
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.026
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
3 |
0.026
|
Yeast |
|
|
protein polymerization
|
GO:0051258 |
57 |
0.026
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.026
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.026
|
|
|
|
regulation of heart rate
|
GO:0002027 |
36 |
0.026
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.026
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.026
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.026
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.026
|
|
|
|
protein refolding
|
GO:0042026 |
1 |
0.025
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.025
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.025
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.025
|
Worm |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.025
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.025
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.025
|
|
|
|
positive regulation of intracellular estrogen receptor signaling pathway
|
GO:0033148 |
4 |
0.025
|
|
|
|
centrosome cycle
|
GO:0007098 |
23 |
0.025
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.024
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.024
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.024
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.024
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.024
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.024
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.024
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.024
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.024
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.024
|
Yeast Worm |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.023
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.023
|
|
|
|
positive regulation of killing of cells of other organism
|
GO:0051712 |
3 |
0.023
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.023
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.023
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
37 |
0.023
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.023
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.022
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.022
|
Yeast |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.022
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.022
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.022
|
Mouse |
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.022
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.022
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.022
|
|
|
|
killing of cells in other organism involved in symbiotic interaction
|
GO:0051883 |
13 |
0.022
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.022
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
18 |
0.022
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.022
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.022
|
Mouse |
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.021
|
|
|
|
regulation of ryanodine sensitive calcium release channel activity
|
GO:0060314 |
10 |
0.021
|
|
|
|
membrane repolarization
|
GO:0086009 |
7 |
0.021
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.021
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.021
|
Yeast |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.021
|
|
|
|
spliceosomal complex assembly
|
GO:0000245 |
6 |
0.021
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.021
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.021
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.021
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.021
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.021
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.021
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.020
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.020
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.020
|
Mouse |
|
|
regulation of phosphoprotein phosphatase activity
|
GO:0043666 |
3 |
0.020
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.020
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.020
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.020
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.020
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.019
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.019
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.019
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.019
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.019
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.019
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.019
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.019
|
Mouse |
|
|
type b pancreatic cell proliferation
|
GO:0044342 |
10 |
0.019
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.018
|
|
|
|
terminal button organization
|
GO:0072553 |
3 |
0.018
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.018
|
Worm |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.018
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.018
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.018
|
|
|
|
positive regulation of atpase activity
|
GO:0032781 |
3 |
0.018
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.018
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.018
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.018
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.018
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.018
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
2 |
0.018
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.018
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
15 |
0.018
|
Mouse |
|
|
negative regulation of rna splicing
|
GO:0033119 |
12 |
0.018
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.017
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.017
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.017
|
|
|
|
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
|
GO:0010880 |
10 |
0.017
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.017
|
Yeast |
|
|
axon guidance
|
GO:0007411 |
141 |
0.017
|
|
|
|
insulin secretion involved in cellular response to glucose stimulus
|
GO:0035773 |
36 |
0.017
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.017
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.017
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
43 |
0.017
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
11 |
0.017
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.017
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.017
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.017
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.017
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.016
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.016
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.016
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.016
|
|
|
|
chromatin remodeling
|
GO:0006338 |
32 |
0.016
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.016
|
Fly |
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.016
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
27 |
0.016
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.016
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.016
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.016
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.016
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.016
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.016
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.016
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.016
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.016
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.016
|
Mouse |
|
|
mrna catabolic process
|
GO:0006402 |
22 |
0.016
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.016
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.016
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.016
|
|
|
|
regulation of dna templated transcription termination
|
GO:0031554 |
1 |
0.016
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.016
|
Yeast |
|
|
forebrain development
|
GO:0030900 |
302 |
0.016
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.015
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.015
|
Mouse |
|
|
inclusion body assembly
|
GO:0070841 |
3 |
0.015
|
Yeast |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.015
|
Fly |
|
|
regulation of water loss via skin
|
GO:0033561 |
16 |
0.015
|
Mouse |
|
|
cell fate specification
|
GO:0001708 |
72 |
0.015
|
Worm |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.015
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.015
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.015
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.015
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.015
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.015
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.015
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.015
|
|
|
|
zygote asymmetric cell division
|
GO:0010070 |
2 |
0.015
|
Worm |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.015
|
Worm Fly |
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
10 |
0.015
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.015
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.015
|
Yeast |
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.015
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.015
|
|
