|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.977
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.950
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.915
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.805
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.769
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.750
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.744
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.704
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.684
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.654
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.648
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.635
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.619
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.615
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.582
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.574
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.565
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.563
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.490
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.488
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.482
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.455
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.452
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.439
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.436
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.429
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.413
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.409
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.368
|
Mouse Fly |
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.368
|
Mouse |
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.357
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.354
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.348
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.345
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.344
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.341
|
Mouse |
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.337
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.337
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.335
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.326
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.322
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.303
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.302
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.301
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.300
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.299
|
Mouse |
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.298
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.270
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.267
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.247
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.246
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.243
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.242
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.241
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.235
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.234
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.232
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.226
|
Mouse |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.226
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.224
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.223
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.219
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.218
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.218
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.215
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.213
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.213
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.211
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.208
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.207
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.207
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.200
|
Mouse |
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.199
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.194
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.193
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.192
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.192
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.192
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.191
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.188
|
Mouse |
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.188
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.184
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.184
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.177
|
Mouse |
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.177
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.174
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.173
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.171
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.170
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.169
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.168
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.165
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.165
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.164
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.162
|
Mouse |
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.161
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.161
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.157
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.154
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.152
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.152
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.151
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.151
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.148
|
Mouse |
|
|
gamma delta t cell lineage commitment
|
GO:0002365 |
1 |
0.148
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.143
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.142
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.142
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.141
|
Mouse |
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.139
|
Mouse |
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.138
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.138
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.138
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.136
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.135
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.128
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.122
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.121
|
|
|
|
natural killer cell inhibitory signaling pathway
|
GO:0002769 |
2 |
0.121
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.120
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.120
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.119
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.117
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.116
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.116
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.115
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.115
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.113
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.112
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.112
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.112
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.111
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.111
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.111
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.109
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.109
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.108
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.106
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.105
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.105
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.105
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.104
|
|
|
|
inner cell mass cell proliferation
|
GO:0001833 |
15 |
0.103
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.102
|
Mouse Fly |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.102
|
Mouse |
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.101
|
Mouse |
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.100
|
Mouse |
|
|
mast cell activation
|
GO:0045576 |
27 |
0.100
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.100
|
Mouse |
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.100
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.099
|
Mouse |
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.098
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.096
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.096
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.094
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.093
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.092
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.092
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.091
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.090
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.089
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.089
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.089
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.088
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.087
|
Mouse |
|
|
membrane invagination
|
GO:0010324 |
17 |
0.086
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.086
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.086
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.086
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.085
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.085
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.084
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.084
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.084
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.084
|
Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.084
|
|
|
|
cellular zinc ion homeostasis
|
GO:0006882 |
9 |
0.083
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.083
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.083
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.081
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.081
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.081
|
Mouse |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.080
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.080
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.080
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.079
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.079
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.079
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.078
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.078
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.078
|
Mouse |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.078
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.077
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.077
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.076
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.076
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.076
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.075
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.075
|
Mouse |
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.075
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.075
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.075
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.074
|
Mouse |
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.074
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.074
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.074
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.073
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.073
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.073
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.073
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.072
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.071
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.071
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.070
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.070
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.070
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.069
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.069
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.069
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.068
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.068
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.067
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.067
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.067
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.066
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.065
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.065
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.065
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.065
|
Mouse |
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.064
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.064
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.064
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.064
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.064
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.063
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.063
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.062
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.061
|
Mouse |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.061
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.061
|
Mouse |
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.061
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.061
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.061
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.059
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.059
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.058
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.058
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.058
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.058
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.058
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.058
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.057
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.057
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.056
|
Mouse |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.056
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.056
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.056
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.055
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.055
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.055
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.054
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.054
|
Mouse |
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.054
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.054
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.053
|
Mouse |
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.053
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.052
|
Zebrafish |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.052
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.052
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.052
|
Mouse |
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.051
|
Mouse |
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.051
|
|
|
|
fibrinolysis
|
GO:0042730 |
3 |
0.051
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.051
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.050
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.050
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.050
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.050
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.050
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.050
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.049
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.049
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.049
|
Mouse |
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.049
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.049
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.049
|
Mouse |
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.048
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.048
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.048
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.048
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.048
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.048
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.048
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.047
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.047
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.047
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.047
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.046
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.046
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.045
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.045
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.045
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.044
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.044
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
1 |
0.044
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.044
|
|
|
|
neutrophil activation
|
GO:0042119 |
9 |
0.044
|
Mouse |
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.044
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.044
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.044
|
Mouse |
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.043
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.043
|
|
|
|
neutrophil activation involved in immune response
|
GO:0002283 |
8 |
0.043
|
Mouse |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.043
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.043
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.043
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.043
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.042
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.042
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.042
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.042
|
|
|
|
mast cell apoptotic process
|
GO:0033024 |
5 |
0.041
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
9 |
0.041
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.041
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.041
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.040
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.040
|
Mouse |
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.039
|
Mouse |
|
|
type b pancreatic cell proliferation
|
GO:0044342 |
10 |
0.039
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.039
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.039
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.039
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.039
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.038
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.038
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.038
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.037
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.037
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.037
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.037
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.037
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.037
|
|
|
|
zinc ion homeostasis
|
GO:0055069 |
10 |
0.037
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.036
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.036
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.036
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.036
|
Mouse |
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.036
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.036
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.036
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.035
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.035
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.035
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.035
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.035
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.035
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.034
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.034
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.034
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.034
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.034
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.034
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.034
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.033
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.033
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.033
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.033
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.033
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.033
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.033
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.033
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.032
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.032
|
|
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.032
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.032
|
|
|
|
positive regulation of interleukin 8 secretion
|
GO:2000484 |
1 |
0.032
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.032
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.031
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.031
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.031
|
Mouse |
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.031
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.031
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.031
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.031
|
Mouse |
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.031
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.030
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.030
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.030
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.030
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.030
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.030
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.030
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.030
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
3 |
0.030
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.029
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.029
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.029
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.029
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.029
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.029
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.029
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.029
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.029
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
6 |
0.029
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.029
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.028
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.028
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.028
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.028
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.028
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.028
|
Mouse |
|
|
lysosome localization
|
GO:0032418 |
20 |
0.028
|
Mouse |
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.028
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.028
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.028
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.028
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.028
|
Mouse |
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.028
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.028
|
|
|
|
learning
|
GO:0007612 |
98 |
0.028
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.028
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.028
|
|
|
|
labyrinthine layer morphogenesis
|
GO:0060713 |
21 |
0.027
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.027
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.027
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
11 |
0.027
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.027
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.027
|
Mouse |
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.027
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.027
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.027
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.027
|
Mouse |
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.026
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.026
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.026
|
Fly |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.026
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.026
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.026
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.026
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.026
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.026
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.026
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.026
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.026
|
|
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
3 |
0.026
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.026
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.025
|
Zebrafish |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.025
|
Mouse |
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.025
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.025
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.025
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.025
|
Mouse |
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.025
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.025
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.025
|
|
|
|
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010579 |
3 |
0.025
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.025
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.025
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.025
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.024
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.024
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.024
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.024
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.024
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.024
|
Mouse |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.024
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.024
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.024
|
Mouse |
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.024
|
Mouse |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.024
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.024
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.023
|
Mouse |
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.023
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.023
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.023
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.023
|
Mouse |
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.023
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.023
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.023
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.023
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.023
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.023
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.023
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
25 |
0.023
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.022
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.022
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.022
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.022
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.022
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.022
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.022
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.021
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.021
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.021
|
Mouse |
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.021
|
|
