Mus musculus

0 known processes

Zwilch

Zwilch, kinetochore associated, homolog (Drosophila)

(Aliases: 2310031L18Rik)

Zwilch biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.325
organelle fission GO:0048285 170 0.206
cellular response to dna damage stimulus GO:0006974 207 0.151
response to radiation GO:0009314 165 0.150
nuclear division GO:0000280 158 0.136
ribonucleoside catabolic process GO:0042454 206 0.135
positive regulation of cellular catabolic process GO:0031331 148 0.129
chromosome organization involved in meiosis GO:0070192 39 0.126
dna repair GO:0006281 107 0.107
chromosome segregation GO:0007059 48 0.091
regulation of microtubule based process GO:0032886 52 0.089
purine nucleoside triphosphate metabolic process GO:0009144 226 0.087
dna recombination GO:0006310 92 0.085
mitotic cell cycle GO:0000278 195 0.085
meiotic cell cycle GO:0051321 122 0.083
mitotic cell cycle process GO:1903047 159 0.081
purine nucleoside catabolic process GO:0006152 205 0.080
protein modification by small protein conjugation or removal GO:0070647 207 0.072
cellular macromolecule catabolic process GO:0044265 206 0.072
regulation of hydrolase activity GO:0051336 246 0.072
ribose phosphate metabolic process GO:0019693 291 0.065
purine ribonucleotide metabolic process GO:0009150 290 0.064
purine ribonucleotide catabolic process GO:0009154 208 0.064
ribonucleotide metabolic process GO:0009259 291 0.059
meiotic nuclear division GO:0007126 115 0.056
carbohydrate derivative catabolic process GO:1901136 231 0.056
ribonucleoside triphosphate catabolic process GO:0009203 199 0.055
ribonucleotide catabolic process GO:0009261 208 0.054
response to uv GO:0009411 44 0.054
nucleoside triphosphate metabolic process GO:0009141 230 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.052
purine nucleotide metabolic process GO:0006163 302 0.052
purine nucleoside metabolic process GO:0042278 241 0.049
purine ribonucleoside metabolic process GO:0046128 241 0.048
regulation of cell cycle process GO:0010564 160 0.048
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
mitotic nuclear division GO:0007067 48 0.046
nucleotide metabolic process GO:0009117 332 0.045
purine nucleoside triphosphate catabolic process GO:0009146 203 0.045
recombinational repair GO:0000725 21 0.043
regulation of cell cycle GO:0051726 281 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.042
purine containing compound catabolic process GO:0072523 213 0.042
cellular protein catabolic process GO:0044257 155 0.041
nucleoside monophosphate metabolic process GO:0009123 85 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
microtubule cytoskeleton organization GO:0000226 157 0.040
glycosyl compound catabolic process GO:1901658 206 0.039
purine containing compound metabolic process GO:0072521 311 0.038
regulation of cellular response to stress GO:0080135 159 0.037
nucleoside catabolic process GO:0009164 206 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
organonitrogen compound catabolic process GO:1901565 264 0.036
gonad development GO:0008406 141 0.035
double strand break repair GO:0006302 48 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.034
positive regulation of apoptotic process GO:0043065 217 0.034
purine nucleotide catabolic process GO:0006195 211 0.033
chromatin organization GO:0006325 206 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.032
cellular ketone metabolic process GO:0042180 84 0.032
regulation of transferase activity GO:0051338 263 0.032
organophosphate catabolic process GO:0046434 232 0.030
protein ubiquitination GO:0016567 171 0.030
response to oxidative stress GO:0006979 123 0.030
protein localization to organelle GO:0033365 185 0.030
nucleotide catabolic process GO:0009166 217 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
chromatin modification GO:0016568 187 0.029
aromatic compound catabolic process GO:0019439 286 0.029
response to light stimulus GO:0009416 135 0.029
meiotic cell cycle process GO:1903046 77 0.028
response to ionizing radiation GO:0010212 42 0.028
anatomical structure homeostasis GO:0060249 145 0.028
double strand break repair via homologous recombination GO:0000724 21 0.028
oxidation reduction process GO:0055114 342 0.027
nucleoside metabolic process GO:0009116 246 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
response to inorganic substance GO:0010035 96 0.026
ubiquitin dependent protein catabolic process GO:0006511 129 0.026
ribonucleoside metabolic process GO:0009119 245 0.025
blastocyst development GO:0001824 80 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
methylation GO:0032259 134 0.024
intracellular protein transport GO:0006886 204 0.024
nucleoside monophosphate catabolic process GO:0009125 59 0.023
meiosis i GO:0007127 60 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
regulation of cellular catabolic process GO:0031329 242 0.022
amine metabolic process GO:0009308 45 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
regulation of mitotic cell cycle phase transition GO:1901990 73 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
dna dependent dna replication GO:0006261 24 0.021
endocytosis GO:0006897 168 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
small gtpase mediated signal transduction GO:0007264 97 0.020
microtubule based process GO:0007017 236 0.020
cell type specific apoptotic process GO:0097285 268 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
peptidyl amino acid modification GO:0018193 336 0.020
positive regulation of protein modification process GO:0031401 299 0.019
translesion synthesis GO:0019985 1 0.019
homeostasis of number of cells GO:0048872 210 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
macromolecule catabolic process GO:0009057 281 0.019
atp metabolic process GO:0046034 75 0.019
atp catabolic process GO:0006200 55 0.019
cellular amine metabolic process GO:0044106 44 0.019
male gamete generation GO:0048232 285 0.019
action potential GO:0001508 78 0.019
maintenance of location GO:0051235 89 0.019
reciprocal dna recombination GO:0035825 16 0.019
mitotic sister chromatid segregation GO:0000070 14 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.019
germ cell development GO:0007281 185 0.018
development of primary sexual characteristics GO:0045137 143 0.018
dna conformation change GO:0071103 37 0.018
attachment of spindle microtubules to kinetochore GO:0008608 4 0.018
response to organonitrogen compound GO:0010243 246 0.018
protein maturation GO:0051604 176 0.018
heterocycle catabolic process GO:0046700 280 0.018
apoptotic signaling pathway GO:0097190 306 0.018
negative regulation of cell cycle GO:0045786 123 0.018
cytoplasmic transport GO:0016482 234 0.018
sister chromatid segregation GO:0000819 20 0.018
regulation of protein maturation GO:1903317 96 0.018
cellular lipid metabolic process GO:0044255 323 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
blastocyst growth GO:0001832 23 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
cellular response to radiation GO:0071478 28 0.017
inner cell mass cell proliferation GO:0001833 15 0.017
regulation of intracellular protein transport GO:0033157 82 0.017
cell cycle checkpoint GO:0000075 47 0.017
ribonucleoside monophosphate catabolic process GO:0009158 57 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
centromere complex assembly GO:0034508 3 0.017
regulation of lymphocyte activation GO:0051249 240 0.016
nuclear dna replication GO:0033260 3 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of proteolysis GO:0030162 164 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
dna ligation GO:0006266 3 0.016
regulation of centriole replication GO:0046599 1 0.016
cellular amino acid metabolic process GO:0006520 103 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
protein import into nucleus GO:0006606 95 0.016
protein import GO:0017038 101 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
cell cycle g1 s phase transition GO:0044843 57 0.015
dna replication independent nucleosome assembly GO:0006336 1 0.015
protein catabolic process GO:0030163 221 0.015
nuclear transport GO:0051169 139 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
synapsis GO:0007129 34 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
b cell activation GO:0042113 161 0.015
membrane organization GO:0061024 245 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.014
heterochromatin organization GO:0070828 4 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
protein localization to nucleus GO:0034504 121 0.014
positive regulation of intracellular transport GO:0032388 70 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
spermatogenesis GO:0007283 284 0.014
cell fate commitment GO:0045165 210 0.014
multicellular organismal signaling GO:0035637 91 0.014
regulation of nucleocytoplasmic transport GO:0046822 73 0.014
positive regulation of kinase activity GO:0033674 155 0.014
regulation of system process GO:0044057 200 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
positive regulation of nfat protein import into nucleus GO:0051533 1 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
intracellular mrna localization GO:0008298 4 0.014
positive regulation of programmed cell death GO:0043068 218 0.013
asymmetric neuroblast division GO:0055059 1 0.013
positive regulation of cell death GO:0010942 224 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
lipid biosynthetic process GO:0008610 179 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
regulation of protein catabolic process GO:0042176 108 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
response to oxygen levels GO:0070482 62 0.013
protein localization to chromosome centromeric region GO:0071459 1 0.013
positive regulation of cytoplasmic transport GO:1903651 40 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
regulation of homeostatic process GO:0032844 182 0.012
regulation of dna recombination GO:0000018 34 0.012
cell division GO:0051301 120 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
regulation of intracellular transport GO:0032386 159 0.012
regulation of protein transport GO:0051223 163 0.012
nitrogen compound transport GO:0071705 271 0.012
regulation of membrane potential GO:0042391 192 0.012
organism emergence from protective structure GO:0071684 4 0.012
cellular response to lipid GO:0071396 145 0.012
protein targeting GO:0006605 143 0.012
lateral inhibition GO:0046331 1 0.012
forebrain development GO:0030900 302 0.012
protein oligomerization GO:0051259 67 0.012
regulation of double strand break repair via homologous recombination GO:0010569 2 0.012
covalent chromatin modification GO:0016569 163 0.012
myeloid cell differentiation GO:0030099 233 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
ras protein signal transduction GO:0007265 77 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
positive regulation of protein localization to nucleus GO:1900182 30 0.011
cell activation involved in immune response GO:0002263 126 0.011
circadian rhythm GO:0007623 114 0.011
carbohydrate homeostasis GO:0033500 128 0.011
cellular response to inorganic substance GO:0071241 37 0.011
regulation of protein localization GO:0032880 231 0.011
regulation of response to dna damage stimulus GO:2001020 34 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
rac protein signal transduction GO:0016601 13 0.011
response to reactive oxygen species GO:0000302 56 0.011
cell adhesion GO:0007155 329 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
immune effector process GO:0002252 321 0.010
positive regulation of intracellular protein transport GO:0090316 42 0.010
myeloid cell homeostasis GO:0002262 114 0.010
hatching GO:0035188 4 0.010
rho protein signal transduction GO:0007266 32 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
response to decreased oxygen levels GO:0036293 59 0.010
response to acid chemical GO:0001101 111 0.010

Zwilch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.213
disease of cellular proliferation DOID:14566 0 0.213
organ system cancer DOID:0050686 0 0.084
thoracic cancer DOID:5093 0 0.023
large intestine cancer DOID:5672 0 0.016
gastrointestinal system cancer DOID:3119 0 0.016
intestinal cancer DOID:10155 0 0.016
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013