Rattus norvegicus

0 known processes

Ctsr

cathepsin R

(Aliases: MGC114553)

Ctsr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.208
homeostatic process GO:0042592 331 0.174
Rat
cellular response to endogenous stimulus GO:0071495 377 0.123
response to peptide hormone GO:0043434 278 0.104
cellular calcium ion homeostasis GO:0006874 160 0.095
cation transmembrane transport GO:0098655 263 0.074
blood circulation GO:0008015 183 0.067
positive regulation of transport GO:0051050 245 0.064
cellular response to growth factor stimulus GO:0071363 162 0.061
cellular response to oxygen containing compound GO:1901701 386 0.059
secretion GO:0046903 307 0.057
response to extracellular stimulus GO:0009991 380 0.051
Rat
response to decreased oxygen levels GO:0036293 237 0.049
cell cell signaling GO:0007267 335 0.047
intracellular signal transduction GO:0035556 314 0.045
carboxylic acid metabolic process GO:0019752 289 0.044
cellular metal ion homeostasis GO:0006875 172 0.044
neuron projection development GO:0031175 273 0.041
positive regulation of secretion by cell GO:1903532 128 0.041
organic acid transport GO:0015849 116 0.040
response to nutrient levels GO:0031667 370 0.037
Rat
regulation of secretion by cell GO:1903530 208 0.035
cellular ion homeostasis GO:0006873 184 0.035
cation transport GO:0006812 382 0.035
action potential GO:0001508 54 0.034
cellular component assembly GO:0022607 360 0.034
response to acid chemical GO:0001101 222 0.034
response to fungicide GO:0060992 20 0.034
cellular chemical homeostasis GO:0055082 247 0.034
cellular cation homeostasis GO:0030003 180 0.033
cell projection organization GO:0030030 302 0.031
synaptic transmission GO:0007268 235 0.031
cellular homeostasis GO:0019725 252 0.030
amino acid transport GO:0006865 70 0.030
programmed cell death GO:0012501 392 0.030
Rat
response to carbohydrate GO:0009743 183 0.030
Rat
macromolecular complex assembly GO:0065003 273 0.030
single organism reproductive process GO:0044702 297 0.030
Rat
metal ion transport GO:0030001 289 0.029
response to oxygen levels GO:0070482 265 0.029
regulation of system process GO:0044057 208 0.029
positive regulation of action potential GO:0045760 8 0.029
response to nutrient GO:0007584 248 0.029
response to nicotine GO:0035094 51 0.028
muscle system process GO:0003012 115 0.028
response to cytokine GO:0034097 215 0.028
chemical homeostasis GO:0048878 292 0.028
nitrogen compound transport GO:0071705 229 0.026
protein complex assembly GO:0006461 263 0.026
acid secretion GO:0046717 48 0.026
single organism behavior GO:0044708 130 0.026
amine metabolic process GO:0009308 38 0.026
regulation of synaptic transmission GO:0050804 141 0.026
response to metal ion GO:0010038 253 0.025
muscle contraction GO:0006936 88 0.025
rhythmic process GO:0048511 156 0.025
regulation of nervous system development GO:0051960 264 0.025
defense response GO:0006952 194 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
central nervous system development GO:0007417 311 0.024
sodium ion transmembrane transport GO:0035725 67 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
cellular amino acid metabolic process GO:0006520 107 0.023
regulation of peptide transport GO:0090087 87 0.023
response to estrogen GO:0043627 232 0.023
response to amino acid GO:0043200 75 0.023
response to alkaloid GO:0043279 132 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
cellular component biogenesis GO:0044085 368 0.022
response to growth factor GO:0070848 189 0.022
head development GO:0060322 247 0.022
protein oligomerization GO:0051259 191 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
monocarboxylic acid transport GO:0015718 52 0.022
response to peptide GO:1901652 292 0.022
divalent inorganic cation transport GO:0072511 134 0.021
reproductive process GO:0022414 372 0.021
Rat
intracellular transport GO:0046907 185 0.021
oxoacid metabolic process GO:0043436 290 0.021
neuron development GO:0048666 286 0.021
ion homeostasis GO:0050801 212 0.021
cellular ketone metabolic process GO:0042180 51 0.021
peptidyl tyrosine phosphorylation GO:0018108 72 0.021
carboxylic acid transport GO:0046942 115 0.020
protein complex biogenesis GO:0070271 263 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
metal ion homeostasis GO:0055065 186 0.020
ovulation cycle GO:0042698 67 0.020
cation homeostasis GO:0055080 195 0.020
organic hydroxy compound transport GO:0015850 77 0.020
micturition GO:0060073 4 0.020
regulation of blood circulation GO:1903522 110 0.019
inflammatory response GO:0006954 150 0.019
neuron differentiation GO:0030182 368 0.019
response to oxidative stress GO:0006979 186 0.019
regulation of neuron projection development GO:0010975 161 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
cellular potassium ion transport GO:0071804 72 0.019
regulation of apoptotic process GO:0042981 335 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
organic anion transport GO:0015711 132 0.018
catabolic process GO:0009056 351 0.018
cellular amine metabolic process GO:0044106 38 0.018
regulation of neurogenesis GO:0050767 247 0.018
regulation of molecular function GO:0065009 398 0.018
brain development GO:0007420 247 0.018
response to ethanol GO:0045471 162 0.018
cellular response to tumor necrosis factor GO:0071356 46 0.018
organic acid metabolic process GO:0006082 292 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
ion transmembrane transport GO:0034220 365 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
regulation of cellular component organization GO:0051128 368 0.017
regulation of cell projection organization GO:0031344 175 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
regulation of programmed cell death GO:0043067 341 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
regulation of catalytic activity GO:0050790 304 0.017
development of primary sexual characteristics GO:0045137 107 0.017
Rat
neurological system process GO:0050877 219 0.017
signal release GO:0023061 145 0.017
positive regulation of signaling GO:0023056 270 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
Rat
nucleic acid templated transcription GO:0097659 379 0.017
regulation of cell development GO:0060284 263 0.017
potassium ion transmembrane transport GO:0071805 71 0.017
regulation of muscle system process GO:0090257 79 0.017
brain renin angiotensin system GO:0002035 3 0.016
purine containing compound metabolic process GO:0072521 253 0.016
single organism intracellular transport GO:1902582 166 0.016
regulation of anatomical structure size GO:0090066 135 0.016
retinal ganglion cell axon guidance GO:0031290 1 0.016
heart process GO:0003015 57 0.016
regulation of hydrolase activity GO:0051336 143 0.016
response to hypoxia GO:0001666 231 0.016
regulation of tube size GO:0035150 89 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
cellular component movement GO:0006928 248 0.015
lipid metabolic process GO:0006629 283 0.015
cognition GO:0050890 92 0.015
regulation of cell differentiation GO:0045595 320 0.015
response to light stimulus GO:0009416 52 0.015
negative regulation of transport GO:0051051 136 0.015
calcium ion homeostasis GO:0055074 162 0.015
behavior GO:0007610 205 0.015
regulation of ion transport GO:0043269 245 0.015
circulatory system process GO:0003013 183 0.015
negative regulation of secretion GO:0051048 82 0.015
response to purine containing compound GO:0014074 126 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.014
peptidyl amino acid modification GO:0018193 126 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
regulation of neuron differentiation GO:0045664 208 0.014
amide transport GO:0042886 105 0.014
regulation of cellular localization GO:0060341 263 0.014
protein localization GO:0008104 191 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.014
circadian rhythm GO:0007623 88 0.014
proteolysis GO:0006508 175 0.014
Rat
secretion by cell GO:0032940 248 0.014
actin filament based process GO:0030029 86 0.014
positive regulation of cell communication GO:0010647 271 0.014
positive regulation of homeostatic process GO:0032846 49 0.014
positive regulation of molecular function GO:0044093 230 0.014
cytoplasmic transport GO:0016482 115 0.014
striated muscle contraction GO:0006941 44 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
sensory perception GO:0007600 101 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
female pregnancy GO:0007565 122 0.013
Rat
neuron death GO:0070997 127 0.013
peptide transport GO:0015833 97 0.013
reproductive system development GO:0061458 128 0.013
Rat
multicellular organismal reproductive process GO:0048609 233 0.013
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of neurological system process GO:0031644 43 0.013
peptide biosynthetic process GO:0043043 3 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
multicellular organismal response to stress GO:0033555 25 0.013
multicellular organismal signaling GO:0035637 44 0.013
potassium ion transport GO:0006813 97 0.013
regulation of neurotransmitter levels GO:0001505 42 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
motor neuron axon guidance GO:0008045 1 0.013
peptide hormone secretion GO:0030072 84 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
peptide metabolic process GO:0006518 32 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
ovulation cycle process GO:0022602 50 0.013
response to estradiol GO:0032355 164 0.013
regulation of action potential GO:0098900 14 0.012
apoptotic process GO:0006915 381 0.012
regulation of rna metabolic process GO:0051252 391 0.012
organelle organization GO:0006996 266 0.012
positive regulation of ion transport GO:0043270 94 0.012
learning or memory GO:0007611 90 0.012
sulfur compound metabolic process GO:0006790 70 0.012
cell growth GO:0016049 104 0.012
cellular component morphogenesis GO:0032989 155 0.012
positive regulation of synaptic transmission GO:0050806 62 0.012
negative regulation of secretion by cell GO:1903531 72 0.012
response to lipopolysaccharide GO:0032496 191 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
heart contraction GO:0060047 57 0.012
response to mechanical stimulus GO:0009612 134 0.012
cellular response to external stimulus GO:0071496 118 0.012
Rat
growth GO:0040007 165 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
regulation of blood vessel size GO:0050880 89 0.012
response to monosaccharide GO:0034284 159 0.012
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
axis specification GO:0009798 4 0.012
positive regulation of nervous system development GO:0051962 178 0.012
nucleoside metabolic process GO:0009116 179 0.012
cell projection morphogenesis GO:0048858 123 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
transcription dna templated GO:0006351 377 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
cardiac muscle contraction GO:0060048 27 0.012
regulation of metal ion transport GO:0010959 118 0.012
cell cycle checkpoint GO:0000075 2 0.012
protein phosphorylation GO:0006468 345 0.012
ossification GO:0001503 70 0.011
Rat
protein complex subunit organization GO:0071822 302 0.011
hormone transport GO:0009914 121 0.011
response to reactive oxygen species GO:0000302 120 0.011
positive regulation of organelle organization GO:0010638 48 0.011
response to camp GO:0051591 91 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
developmental process involved in reproduction GO:0003006 159 0.011
Rat
positive regulation of cell motility GO:2000147 97 0.011
sequestering of metal ion GO:0051238 9 0.011
macromolecule localization GO:0033036 252 0.011
nucleotide metabolic process GO:0009117 279 0.011
olfactory behavior GO:0042048 2 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
regulation of phosphate metabolic process GO:0019220 349 0.010
anion transport GO:0006820 178 0.010
regulation of ion homeostasis GO:2000021 63 0.010
regulation of secretion GO:0051046 224 0.010
hormone secretion GO:0046879 115 0.010
reproduction GO:0000003 245 0.010
Rat
positive regulation of cellular component organization GO:0051130 200 0.010
response to biotic stimulus GO:0009607 226 0.010
cardiac conduction GO:0061337 2 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
cellular response to peptide GO:1901653 133 0.010
regulation of heart contraction GO:0008016 48 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
positive regulation of amine transport GO:0051954 26 0.010
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.010
regulation of muscle contraction GO:0006937 53 0.010

Ctsr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cardiovascular system disease DOID:1287 0 0.025
nervous system disease DOID:863 0 0.021
central nervous system disease DOID:331 0 0.014
muscular disease DOID:0080000 0 0.011
musculoskeletal system disease DOID:17 0 0.011
muscle tissue disease DOID:66 0 0.011
endocrine system disease DOID:28 0 0.010