Rattus norvegicus

0 known processes

Ctsw

cathepsin W

(Aliases: MGC112764)

Ctsw biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.119
positive regulation of gene expression GO:0010628 244 0.091
regulation of transcription dna templated GO:0006355 374 0.085
cell motility GO:0048870 202 0.076
response to nutrient GO:0007584 248 0.075
positive regulation of response to stimulus GO:0048584 285 0.072
response to extracellular stimulus GO:0009991 380 0.069
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.066
organophosphate metabolic process GO:0019637 370 0.064
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.064
regulation of rna biosynthetic process GO:2001141 381 0.061
negative regulation of cellular metabolic process GO:0031324 281 0.061
transcription dna templated GO:0006351 377 0.060
cellular component movement GO:0006928 248 0.060
intracellular signal transduction GO:0035556 314 0.057
cell migration GO:0016477 197 0.056
regulation of rna metabolic process GO:0051252 391 0.053
response to estrogen GO:0043627 232 0.052
regeneration GO:0031099 163 0.052
immune response GO:0006955 104 0.051
amine metabolic process GO:0009308 38 0.048
rna metabolic process GO:0016070 406 0.047
response to growth factor GO:0070848 189 0.046
response to peptide hormone GO:0043434 278 0.045
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.045
regulation of cellular localization GO:0060341 263 0.044
negative regulation of cellular biosynthetic process GO:0031327 161 0.043
defense response GO:0006952 194 0.042
localization of cell GO:0051674 202 0.042
enzyme linked receptor protein signaling pathway GO:0007167 116 0.042
regulation of immune system process GO:0002682 123 0.042
regulation of signal transduction GO:0009966 318 0.042
regulation of cell development GO:0060284 263 0.041
regulation of cell differentiation GO:0045595 320 0.041
locomotion GO:0040011 237 0.040
positive regulation of cell proliferation GO:0008284 249 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
positive regulation of rna metabolic process GO:0051254 203 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
programmed cell death GO:0012501 392 0.038
regulation of molecular function GO:0065009 398 0.038
positive regulation of biosynthetic process GO:0009891 319 0.038
homeostatic process GO:0042592 331 0.038
intracellular transport GO:0046907 185 0.037
single organism reproductive process GO:0044702 297 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
single organism cellular localization GO:1902580 102 0.036
regulation of intracellular signal transduction GO:1902531 218 0.036
positive regulation of cell differentiation GO:0045597 217 0.035
organonitrogen compound biosynthetic process GO:1901566 167 0.035
rna biosynthetic process GO:0032774 380 0.035
cardiovascular system development GO:0072358 134 0.035
immune system process GO:0002376 204 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.035
negative regulation of metabolic process GO:0009892 331 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
cellular amine metabolic process GO:0044106 38 0.034
regulation of locomotion GO:0040012 148 0.034
cellular homeostasis GO:0019725 252 0.034
regulation of cell proliferation GO:0042127 359 0.034
cellular component morphogenesis GO:0032989 155 0.034
regulation of phosphate metabolic process GO:0019220 349 0.033
response to cytokine GO:0034097 215 0.033
gland development GO:0048732 155 0.033
regulation of programmed cell death GO:0043067 341 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
negative regulation of innate immune response GO:0045824 4 0.032
nucleic acid templated transcription GO:0097659 379 0.032
regulation of cellular component movement GO:0051270 150 0.031
negative regulation of biosynthetic process GO:0009890 168 0.031
response to mechanical stimulus GO:0009612 134 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
positive regulation of apoptotic process GO:0043065 154 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.030
inflammatory response GO:0006954 150 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
developmental process involved in reproduction GO:0003006 159 0.030
ion homeostasis GO:0050801 212 0.030
regulation of cell motility GO:2000145 131 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
anatomical structure morphogenesis GO:0009653 298 0.030
response to biotic stimulus GO:0009607 226 0.030
negative regulation of cell proliferation GO:0008285 119 0.029
regulation of immune response GO:0050776 55 0.029
chemical homeostasis GO:0048878 292 0.029
circulatory system process GO:0003013 183 0.028
organic acid metabolic process GO:0006082 292 0.028
response to inorganic substance GO:0010035 377 0.028
single organism intracellular transport GO:1902582 166 0.028
regulation of neurogenesis GO:0050767 247 0.028
negative regulation of gene expression GO:0010629 199 0.028
negative regulation of response to stimulus GO:0048585 155 0.027
response to purine containing compound GO:0014074 126 0.027
epithelial cell proliferation GO:0050673 54 0.027
secretion GO:0046903 307 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
positive regulation of cell death GO:0010942 184 0.026
response to oxygen levels GO:0070482 265 0.026
response to metal ion GO:0010038 253 0.026
regulation of neuron death GO:1901214 115 0.026
reproductive process GO:0022414 372 0.026
response to vitamin GO:0033273 131 0.025
reproduction GO:0000003 245 0.025
organ regeneration GO:0031100 101 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
positive regulation of protein metabolic process GO:0051247 178 0.024
single organism biosynthetic process GO:0044711 342 0.024
cell type specific apoptotic process GO:0097285 134 0.024
neuron death GO:0070997 127 0.024
regulation of apoptotic process GO:0042981 335 0.024
response to external biotic stimulus GO:0043207 221 0.024
response to ketone GO:1901654 182 0.024
positive regulation of neurogenesis GO:0050769 165 0.024
positive regulation of cellular component movement GO:0051272 102 0.023
regulation of cell migration GO:0030334 128 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
positive regulation of developmental process GO:0051094 283 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
protein localization GO:0008104 191 0.023
protein phosphorylation GO:0006468 345 0.023
apoptotic process GO:0006915 381 0.022
regulation of nervous system development GO:0051960 264 0.022
tube development GO:0035295 89 0.022
response to wounding GO:0009611 254 0.022
neuron differentiation GO:0030182 368 0.022
response to insulin GO:0032868 133 0.022
cellular catabolic process GO:0044248 295 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
response to amino acid GO:0043200 75 0.022
response to corticosteroid GO:0031960 235 0.022
immune effector process GO:0002252 53 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
positive regulation of locomotion GO:0040017 102 0.021
acute inflammatory response GO:0002526 58 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
cellular component biogenesis GO:0044085 368 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
macromolecular complex assembly GO:0065003 273 0.021
lymphocyte migration GO:0072676 3 0.021
regulation of catalytic activity GO:0050790 304 0.021
response to glucose GO:0009749 136 0.021
mapk cascade GO:0000165 140 0.020
ossification GO:0001503 70 0.020
negative regulation of cell communication GO:0010648 158 0.020
neuron projection development GO:0031175 273 0.020
cellular component assembly GO:0022607 360 0.020
negative regulation of signaling GO:0023057 157 0.020
proteolysis GO:0006508 175 0.020
cell projection organization GO:0030030 302 0.020
organelle organization GO:0006996 266 0.020
eye morphogenesis GO:0048592 4 0.020
neuron development GO:0048666 286 0.020
regulation of neuron differentiation GO:0045664 208 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
oxoacid metabolic process GO:0043436 290 0.019
regulation of membrane potential GO:0042391 110 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
regulation of protein metabolic process GO:0051246 289 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
response to peptide GO:1901652 292 0.019
protein complex subunit organization GO:0071822 302 0.019
nucleotide metabolic process GO:0009117 279 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
positive regulation of nervous system development GO:0051962 178 0.019
positive regulation of cell migration GO:0030335 96 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
action potential GO:0001508 54 0.018
response to glucocorticoid GO:0051384 223 0.018
response to oxidative stress GO:0006979 186 0.018
regulation of cellular component organization GO:0051128 368 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
angiogenesis GO:0001525 53 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
negative regulation of cell death GO:0060548 229 0.018
purine containing compound metabolic process GO:0072521 253 0.018
tissue development GO:0009888 252 0.018
positive regulation of programmed cell death GO:0043068 157 0.017
reproductive structure development GO:0048608 128 0.017
positive regulation of blood circulation GO:1903524 65 0.017
positive regulation of signaling GO:0023056 270 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of cell communication GO:0010647 271 0.017
epithelium development GO:0060429 96 0.017
response to tumor necrosis factor GO:0034612 56 0.017
protein complex biogenesis GO:0070271 263 0.017
establishment of protein localization GO:0045184 141 0.016
eosinophil migration GO:0072677 3 0.016
response to activity GO:0014823 73 0.016
erk1 and erk2 cascade GO:0070371 48 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
cellular response to stress GO:0033554 269 0.016
response to acid chemical GO:0001101 222 0.016
positive regulation of myeloid leukocyte differentiation GO:0002763 7 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
cellular ketone metabolic process GO:0042180 51 0.016
negative regulation of molecular function GO:0044092 133 0.016
response to hypoxia GO:0001666 231 0.016
catabolic process GO:0009056 351 0.016
cellular response to acid chemical GO:0071229 75 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
multi multicellular organism process GO:0044706 138 0.016
positive regulation of intracellular signal transduction GO:1902533 138 0.015
cellular protein localization GO:0034613 122 0.015
regulation of secretion by cell GO:1903530 208 0.015
sex differentiation GO:0007548 113 0.015
renal system development GO:0072001 67 0.015
negative regulation of transport GO:0051051 136 0.015
positive regulation of transport GO:0051050 245 0.015
wound healing GO:0042060 122 0.015
viral transcription GO:0019083 2 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
aging GO:0007568 241 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
protein complex assembly GO:0006461 263 0.015
positive regulation of immune system process GO:0002684 90 0.015
response to camp GO:0051591 91 0.015
salivary gland development GO:0007431 3 0.015
negative regulation of signal transduction GO:0009968 83 0.014
regulation of secretion GO:0051046 224 0.014
regulation of mapk cascade GO:0043408 116 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of phosphorylation GO:0042325 248 0.014
response to lipopolysaccharide GO:0032496 191 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
rhythmic process GO:0048511 156 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
leukocyte mediated immunity GO:0002443 28 0.014
cation homeostasis GO:0055080 195 0.014
cellular ion homeostasis GO:0006873 184 0.014
liver development GO:0001889 90 0.014
response to ethanol GO:0045471 162 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
cation transport GO:0006812 382 0.014
response to monosaccharide GO:0034284 159 0.014
eye development GO:0001654 50 0.014
gastrulation GO:0007369 2 0.014
response to carbohydrate GO:0009743 183 0.014
lipid metabolic process GO:0006629 283 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
heart contraction GO:0060047 57 0.014
regulation of neuron projection development GO:0010975 161 0.013
bmp signaling pathway GO:0030509 4 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
positive regulation of protein modification process GO:0031401 142 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
hematopoietic or lymphoid organ development GO:0048534 36 0.013
pseudopodium assembly GO:0031269 3 0.013
transmembrane transport GO:0055085 412 0.013
response to bacterium GO:0009617 200 0.013
negative regulation of developmental process GO:0051093 125 0.013
blood circulation GO:0008015 183 0.013
positive regulation of molecular function GO:0044093 230 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
multi organism reproductive process GO:0044703 262 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
organic cyclic compound catabolic process GO:1901361 175 0.012
cellular macromolecule localization GO:0070727 122 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
reproductive system development GO:0061458 128 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
metal ion homeostasis GO:0055065 186 0.012
cellular lipid metabolic process GO:0044255 208 0.012
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
single organism organelle organization GO:1902589 180 0.012
respiratory system development GO:0060541 45 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
sensory organ development GO:0007423 74 0.012
gamete generation GO:0007276 124 0.012
biological adhesion GO:0022610 110 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
nitrogen compound transport GO:0071705 229 0.012
regulation of homeostatic process GO:0032844 101 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
intracellular protein transport GO:0006886 79 0.012
regulation of protein modification process GO:0031399 194 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
meiotic cell cycle process GO:1903046 3 0.011
cytoplasmic transport GO:0016482 115 0.011
embryonic skeletal system development GO:0048706 3 0.011
secretion by cell GO:0032940 248 0.011
regulation of defense response GO:0031347 68 0.011
response to hexose GO:0009746 144 0.011
regulation of cell projection organization GO:0031344 175 0.011
sequestering of metal ion GO:0051238 9 0.011
calcium ion homeostasis GO:0055074 162 0.011
multicellular organism reproduction GO:0032504 233 0.011
negative regulation of cell development GO:0010721 82 0.011
protein transport GO:0015031 132 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
cytokine biosynthetic process GO:0042089 3 0.011
regulation of protein transport GO:0051223 68 0.011
positive regulation of cell motility GO:2000147 97 0.011
blood vessel morphogenesis GO:0048514 58 0.011
protein oligomerization GO:0051259 191 0.011
growth GO:0040007 165 0.011
positive regulation of lipid kinase activity GO:0090218 2 0.011
regulation of immune effector process GO:0002697 32 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
positive regulation of signal transduction GO:0009967 175 0.011
cellular cation homeostasis GO:0030003 180 0.011
positive regulation of endothelial cell migration GO:0010595 4 0.011
embryonic limb morphogenesis GO:0030326 4 0.011
cell cycle GO:0007049 101 0.011
salivary gland morphogenesis GO:0007435 1 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
gonad development GO:0008406 104 0.011
erbb signaling pathway GO:0038127 23 0.011
kidney development GO:0001822 67 0.011
nucleoside metabolic process GO:0009116 179 0.011
cell cell signaling GO:0007267 335 0.011
regulation of intracellular transport GO:0032386 65 0.011
cellular response to tumor necrosis factor GO:0071356 46 0.010
regulation of epithelial cell proliferation GO:0050678 49 0.010
peptidyl amino acid modification GO:0018193 126 0.010
response to ionizing radiation GO:0010212 59 0.010
viral gene expression GO:0019080 2 0.010
formation of primary germ layer GO:0001704 1 0.010
regulation of kinase activity GO:0043549 117 0.010
negative regulation of neuron death GO:1901215 69 0.010
epidermal growth factor receptor signaling pathway GO:0007173 23 0.010
limb morphogenesis GO:0035108 4 0.010
ras protein signal transduction GO:0007265 29 0.010
heterocycle catabolic process GO:0046700 167 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
response to alkaloid GO:0043279 132 0.010
macromolecule localization GO:0033036 252 0.010
regulation of protein localization GO:0032880 81 0.010
immune system development GO:0002520 41 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
carboxylic acid transport GO:0046942 115 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
cellular response to drug GO:0035690 30 0.010
glycosyl compound metabolic process GO:1901657 182 0.010

Ctsw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017
nervous system disease DOID:863 0 0.012
bone disease DOID:0080001 0 0.012