Rattus norvegicus

51 known processes

Trim63

tripartite motif-containing 63

(Aliases: Murf1,Rnf28,Murf)

Trim63 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.113
cation transport GO:0006812 382 0.098
cellular component assembly GO:0022607 360 0.096
cellular component biogenesis GO:0044085 368 0.093
cellular chemical homeostasis GO:0055082 247 0.080
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.075
transmembrane transport GO:0055085 412 0.071
homeostatic process GO:0042592 331 0.069
cellular ion homeostasis GO:0006873 184 0.068
cation transmembrane transport GO:0098655 263 0.062
organelle organization GO:0006996 266 0.059
organic acid metabolic process GO:0006082 292 0.058
synaptic transmission GO:0007268 235 0.058
protein oligomerization GO:0051259 191 0.057
positive regulation of cellular component organization GO:0051130 200 0.056
neuron development GO:0048666 286 0.055
programmed cell death GO:0012501 392 0.055
metal ion transport GO:0030001 289 0.054
cardiovascular system development GO:0072358 134 0.054
multicellular organism reproduction GO:0032504 233 0.051
macromolecular complex assembly GO:0065003 273 0.050
regulation of cellular component organization GO:0051128 368 0.047
anatomical structure morphogenesis GO:0009653 298 0.047
ion homeostasis GO:0050801 212 0.045
response to extracellular stimulus GO:0009991 380 0.045
positive regulation of developmental process GO:0051094 283 0.045
macromolecular complex subunit organization GO:0043933 339 0.045
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.045
muscle system process GO:0003012 115 0.045
protein complex assembly GO:0006461 263 0.044
vesicle mediated transport GO:0016192 181 0.044
anatomical structure formation involved in morphogenesis GO:0048646 83 0.044
cellular response to stress GO:0033554 269 0.044
rna biosynthetic process GO:0032774 380 0.044
cellular metal ion homeostasis GO:0006875 172 0.043
organic substance catabolic process GO:1901575 316 0.043
Mouse
cellular macromolecule localization GO:0070727 122 0.043
regulation of ion transport GO:0043269 245 0.043
regulation of muscle system process GO:0090257 79 0.043
locomotion GO:0040011 237 0.042
cellular homeostasis GO:0019725 252 0.041
intracellular signal transduction GO:0035556 314 0.041
response to inorganic substance GO:0010035 377 0.041
carboxylic acid metabolic process GO:0019752 289 0.039
oxoacid metabolic process GO:0043436 290 0.039
protein phosphorylation GO:0006468 345 0.038
regulation of apoptotic process GO:0042981 335 0.038
circulatory system development GO:0072359 134 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
Mouse
muscle contraction GO:0006936 88 0.037
single organism organelle organization GO:1902589 180 0.037
regulation of heart contraction GO:0008016 48 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
aging GO:0007568 241 0.036
protein complex subunit organization GO:0071822 302 0.035
cation homeostasis GO:0055080 195 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
response to cytokine GO:0034097 215 0.035
neuron projection development GO:0031175 273 0.035
response to nutrient levels GO:0031667 370 0.035
regulation of cell differentiation GO:0045595 320 0.034
apoptotic process GO:0006915 381 0.034
regulation of cell proliferation GO:0042127 359 0.034
negative regulation of metabolic process GO:0009892 331 0.033
single organism catabolic process GO:0044712 283 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
reproductive process GO:0022414 372 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
positive regulation of gene expression GO:0010628 244 0.032
positive regulation of cell death GO:0010942 184 0.032
calcium ion homeostasis GO:0055074 162 0.031
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.031
metal ion homeostasis GO:0055065 186 0.031
regulation of cell projection organization GO:0031344 175 0.030
divalent inorganic cation homeostasis GO:0072507 165 0.030
gland development GO:0048732 155 0.029
regulation of programmed cell death GO:0043067 341 0.029
cellular response to organonitrogen compound GO:0071417 197 0.028
muscle structure development GO:0061061 87 0.028
sexual reproduction GO:0019953 148 0.028
response to oxygen levels GO:0070482 265 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.028
macromolecule localization GO:0033036 252 0.027
growth GO:0040007 165 0.027
protein complex biogenesis GO:0070271 263 0.027
regulation of transcription dna templated GO:0006355 374 0.026
regulation of system process GO:0044057 208 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
brain development GO:0007420 247 0.026
positive regulation of cell development GO:0010720 176 0.025
rna metabolic process GO:0016070 406 0.025
negative regulation of cell death GO:0060548 229 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
cellular amine metabolic process GO:0044106 38 0.025
striated muscle contraction GO:0006941 44 0.025
heart morphogenesis GO:0003007 3 0.025
response to growth factor GO:0070848 189 0.025
cell projection organization GO:0030030 302 0.025
head development GO:0060322 247 0.025
negative regulation of gene expression GO:0010629 199 0.024
cellular cation homeostasis GO:0030003 180 0.024
cardiac muscle cell development GO:0055013 16 0.024
catabolic process GO:0009056 351 0.024
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
response to decreased oxygen levels GO:0036293 237 0.024
heart development GO:0007507 72 0.024
cellular protein localization GO:0034613 122 0.024
response to acid chemical GO:0001101 222 0.024
amine metabolic process GO:0009308 38 0.024
inorganic ion transmembrane transport GO:0098660 229 0.023
response to nutrient GO:0007584 248 0.023
regulation of rna metabolic process GO:0051252 391 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
carboxylic acid transport GO:0046942 115 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.023
cardiac muscle contraction GO:0060048 27 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
cellular ketone metabolic process GO:0042180 51 0.023
protein localization GO:0008104 191 0.023
intracellular transport GO:0046907 185 0.023
regulation of muscle contraction GO:0006937 53 0.022
circulatory system process GO:0003013 183 0.022
response to hypoxia GO:0001666 231 0.022
neuron differentiation GO:0030182 368 0.022
reproduction GO:0000003 245 0.022
tissue development GO:0009888 252 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
positive regulation of neuron projection development GO:0010976 99 0.021
divalent inorganic cation transport GO:0072511 134 0.021
actin filament based process GO:0030029 86 0.021
positive regulation of cell communication GO:0010647 271 0.021
anion transport GO:0006820 178 0.021
response to estrogen GO:0043627 232 0.021
neuron death GO:0070997 127 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
Mouse
inorganic cation transmembrane transport GO:0098662 202 0.021
secretion GO:0046903 307 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
biological adhesion GO:0022610 110 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
regulation of neuron death GO:1901214 115 0.020
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
multi organism reproductive process GO:0044703 262 0.020
regulation of cytoskeleton organization GO:0051493 49 0.019
response to vitamin GO:0033273 131 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
regulation of blood circulation GO:1903522 110 0.019
response to radiation GO:0009314 137 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
cellular macromolecular complex assembly GO:0034622 58 0.019
membrane organization GO:0061024 94 0.018
cardiac chamber development GO:0003205 1 0.018
tube development GO:0035295 89 0.018
organic hydroxy compound transport GO:0015850 77 0.018
endoplasmic reticulum to cytosol transport GO:1903513 4 0.018
transcription dna templated GO:0006351 377 0.018
response to activity GO:0014823 73 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
Mouse
response to peptide GO:1901652 292 0.017
developmental growth GO:0048589 100 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
positive regulation of programmed cell death GO:0043068 157 0.016
regulation of cell development GO:0060284 263 0.016
single organism reproductive process GO:0044702 297 0.016
regulation of nervous system development GO:0051960 264 0.016
secretion by cell GO:0032940 248 0.016
regulation of catabolic process GO:0009894 113 0.016
response to ketone GO:1901654 182 0.016
Mouse
positive regulation of neuron differentiation GO:0045666 126 0.016
regulation of protein modification process GO:0031399 194 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
cytoplasmic transport GO:0016482 115 0.016
single organism biosynthetic process GO:0044711 342 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
proteolysis GO:0006508 175 0.016
Mouse
chromosome segregation GO:0007059 2 0.016
cellular response to cytokine stimulus GO:0071345 127 0.015
nitrogen compound transport GO:0071705 229 0.015
defense response GO:0006952 194 0.015
regulation of metal ion transport GO:0010959 118 0.015
ventricular cardiac muscle cell action potential GO:0086005 2 0.015
cellular response to lipid GO:0071396 201 0.015
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.015
response to heat GO:0009408 60 0.015
response to oxidative stress GO:0006979 186 0.015
organic anion transport GO:0015711 132 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
central nervous system development GO:0007417 311 0.015
muscle tissue development GO:0060537 58 0.015
regulation of phosphorylation GO:0042325 248 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
purine containing compound metabolic process GO:0072521 253 0.015
cardiac muscle cell contraction GO:0086003 10 0.015
neural crest cell development GO:0014032 2 0.015
anterior posterior pattern specification GO:0009952 1 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
regulation of neurogenesis GO:0050767 247 0.015
mapk cascade GO:0000165 140 0.015
striated muscle tissue development GO:0014706 58 0.014
potassium ion transport GO:0006813 97 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
response to wounding GO:0009611 254 0.014
cellular catabolic process GO:0044248 295 0.014
Mouse
regulation of anatomical structure size GO:0090066 135 0.014
cellular component movement GO:0006928 248 0.014
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.014
endocytosis GO:0006897 84 0.014
gamete generation GO:0007276 124 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
axis specification GO:0009798 4 0.014
regulation of organelle organization GO:0033043 80 0.014
regulation of calcium ion transport GO:0051924 77 0.014
divalent metal ion transport GO:0070838 132 0.014
response to ethanol GO:0045471 162 0.014
acetyl coa metabolic process GO:0006084 17 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
response to estradiol GO:0032355 164 0.014
cell adhesion GO:0007155 110 0.014
chemical homeostasis GO:0048878 292 0.014
muscle cell differentiation GO:0042692 52 0.014
sequestering of calcium ion GO:0051208 8 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
mitotic sister chromatid separation GO:0051306 1 0.014
limb morphogenesis GO:0035108 4 0.014
regulation of cellular localization GO:0060341 263 0.014
calcium ion transport GO:0006816 131 0.013
localization of cell GO:0051674 202 0.013
choline transport GO:0015871 4 0.013
response to mechanical stimulus GO:0009612 134 0.013
response to corticosteroid GO:0031960 235 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
heart process GO:0003015 57 0.013
female pregnancy GO:0007565 122 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.013
regulation of molecular function GO:0065009 398 0.013
regulation of chromosome segregation GO:0051983 1 0.013
vasculature development GO:0001944 70 0.013
rhythmic process GO:0048511 156 0.013
tissue remodeling GO:0048771 40 0.013
regulation of neuron projection development GO:0010975 161 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
cell cycle checkpoint GO:0000075 2 0.013
cell cycle GO:0007049 101 0.012
heart contraction GO:0060047 57 0.012
regulation of homeostatic process GO:0032844 101 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
regulation of neuron differentiation GO:0045664 208 0.012
regulation of membrane potential GO:0042391 110 0.012
response to camp GO:0051591 91 0.012
neurological system process GO:0050877 219 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
regulation of response to stress GO:0080134 126 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
skeletal muscle cell differentiation GO:0035914 2 0.012
regulation of striated muscle contraction GO:0006942 21 0.012
cell type specific apoptotic process GO:0097285 134 0.012
regulation of growth GO:0040008 105 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
muscle organ morphogenesis GO:0048644 1 0.012
positive regulation of skeletal muscle tissue regeneration GO:0043415 1 0.012
nucleotide metabolic process GO:0009117 279 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
immune system process GO:0002376 204 0.012
heterocycle catabolic process GO:0046700 167 0.012
cytoskeleton organization GO:0007010 111 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
regulation of membrane repolarization GO:0060306 1 0.012
regeneration GO:0031099 163 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
membrane depolarization during action potential GO:0086010 1 0.012
response to external biotic stimulus GO:0043207 221 0.012
single organism membrane organization GO:0044802 74 0.012
cold acclimation GO:0009631 1 0.011
cellular response to external stimulus GO:0071496 118 0.011
male gamete generation GO:0048232 99 0.011
blood vessel development GO:0001568 69 0.011
wound healing GO:0042060 122 0.011
regulation of protein metabolic process GO:0051246 289 0.011
negative regulation of transport GO:0051051 136 0.011
oligopeptide transport GO:0006857 4 0.011
maintenance of location GO:0051235 17 0.011
catecholamine transport GO:0051937 37 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
response to starvation GO:0042594 59 0.011
mitotic cell cycle checkpoint GO:0007093 1 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
cardiac conduction GO:0061337 2 0.011
organophosphate metabolic process GO:0019637 370 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
Mouse
metaphase anaphase transition of cell cycle GO:0044784 1 0.011
circadian rhythm GO:0007623 88 0.011
cell activation GO:0001775 97 0.011
establishment of protein localization GO:0045184 141 0.011
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of nervous system development GO:0051962 178 0.011
establishment of tissue polarity GO:0007164 2 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
response to glucocorticoid GO:0051384 223 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
response to other organism GO:0051707 220 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
regulation of synaptic transmission GO:0050804 141 0.011
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cellular response to oxygen levels GO:0071453 60 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
regulation of catalytic activity GO:0050790 304 0.011
response to peptide hormone GO:0043434 278 0.010
vascular process in circulatory system GO:0003018 96 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
positive regulation of blood circulation GO:1903524 65 0.010
response to biotic stimulus GO:0009607 226 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
programmed necrotic cell death GO:0097300 2 0.010
sister chromatid segregation GO:0000819 1 0.010
dephosphorylation GO:0016311 98 0.010
organ morphogenesis GO:0009887 75 0.010
cellular response to lipopolysaccharide GO:0071222 55 0.010
regulation of necroptotic process GO:0060544 2 0.010
regulation of transmembrane transport GO:0034762 122 0.010

Trim63 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.035
disease of anatomical entity DOID:7 0 0.035
musculoskeletal system disease DOID:17 0 0.035
muscle tissue disease DOID:66 0 0.035
myopathy DOID:423 0 0.031
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011