Rattus norvegicus

5 known processes

Scap

SREBF chaperone

Scap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell migration GO:0016477 197 0.223
cell motility GO:0048870 202 0.177
cell projection organization GO:0030030 302 0.131
localization of cell GO:0051674 202 0.129
protein complex assembly GO:0006461 263 0.128
cellular component movement GO:0006928 248 0.107
anatomical structure morphogenesis GO:0009653 298 0.100
organelle organization GO:0006996 266 0.089
macromolecular complex subunit organization GO:0043933 339 0.088
protein complex subunit organization GO:0071822 302 0.085
macromolecular complex assembly GO:0065003 273 0.085
rna metabolic process GO:0016070 406 0.080
Human
protein complex biogenesis GO:0070271 263 0.080
cell morphogenesis GO:0000902 142 0.078
central nervous system development GO:0007417 311 0.076
neuron differentiation GO:0030182 368 0.075
transcription from rna polymerase ii promoter GO:0006366 252 0.073
Human
regulation of cellular component organization GO:0051128 368 0.072
locomotion GO:0040011 237 0.069
neuron development GO:0048666 286 0.068
single organism organelle organization GO:1902589 180 0.068
regulation of cell development GO:0060284 263 0.067
regulation of locomotion GO:0040012 148 0.066
regulation of rna biosynthetic process GO:2001141 381 0.066
Human
regulation of nervous system development GO:0051960 264 0.063
regulation of cell differentiation GO:0045595 320 0.061
negative regulation of macromolecule metabolic process GO:0010605 260 0.059
regulation of signal transduction GO:0009966 318 0.059
sensory organ development GO:0007423 74 0.057
regulation of anatomical structure morphogenesis GO:0022603 141 0.054
reproductive process GO:0022414 372 0.054
negative regulation of metabolic process GO:0009892 331 0.053
regulation of cell proliferation GO:0042127 359 0.052
regulation of cellular ketone metabolic process GO:0010565 27 0.051
Mouse
immune system process GO:0002376 204 0.050
neuron projection development GO:0031175 273 0.050
regulation of multicellular organismal development GO:2000026 376 0.050
cellular ketone metabolic process GO:0042180 51 0.049
Mouse
single organism reproductive process GO:0044702 297 0.048
cellular response to stress GO:0033554 269 0.047
Human
enzyme linked receptor protein signaling pathway GO:0007167 116 0.047
response to wounding GO:0009611 254 0.046
regulation of cellular amino acid metabolic process GO:0006521 2 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.044
asymmetric protein localization GO:0008105 2 0.043
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.042
apoptotic process GO:0006915 381 0.042
regulation of catalytic activity GO:0050790 304 0.040
regulation of molecular function GO:0065009 398 0.040
regulation of cell motility GO:2000145 131 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
Human
carboxylic acid metabolic process GO:0019752 289 0.039
Mouse
cytoskeleton organization GO:0007010 111 0.038
immune response GO:0006955 104 0.038
cellular response to growth factor stimulus GO:0071363 162 0.037
regulation of neurogenesis GO:0050767 247 0.037
multi organism reproductive process GO:0044703 262 0.037
regulation of cell projection organization GO:0031344 175 0.037
nucleic acid templated transcription GO:0097659 379 0.036
Human
positive regulation of cellular component organization GO:0051130 200 0.036
programmed cell death GO:0012501 392 0.035
synaptic transmission GO:0007268 235 0.035
cellular component assembly GO:0022607 360 0.035
taxis GO:0042330 67 0.035
response to nutrient levels GO:0031667 370 0.034
regulation of cellular component movement GO:0051270 150 0.034
cell adhesion GO:0007155 110 0.034
positive regulation of cell differentiation GO:0045597 217 0.033
secretion GO:0046903 307 0.033
oxoacid metabolic process GO:0043436 290 0.033
Mouse
brain development GO:0007420 247 0.033
protein phosphorylation GO:0006468 345 0.033
cellular component biogenesis GO:0044085 368 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
Human
negative regulation of gene expression GO:0010629 199 0.032
regulation of neuron projection development GO:0010975 161 0.031
amine metabolic process GO:0009308 38 0.031
single organism biosynthetic process GO:0044711 342 0.031
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
cell projection morphogenesis GO:0048858 123 0.031
regulation of programmed cell death GO:0043067 341 0.030
transcription dna templated GO:0006351 377 0.030
Human
response to growth factor GO:0070848 189 0.030
regulation of neuron differentiation GO:0045664 208 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
cellular response to oxygen containing compound GO:1901701 386 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
growth GO:0040007 165 0.029
head development GO:0060322 247 0.029
peptidyl amino acid modification GO:0018193 126 0.029
neuron projection morphogenesis GO:0048812 122 0.029
axonogenesis GO:0007409 71 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.029
cell cell signaling GO:0007267 335 0.028
negative regulation of response to stimulus GO:0048585 155 0.028
regulation of cell migration GO:0030334 128 0.028
gliogenesis GO:0042063 93 0.028
single organism intracellular transport GO:1902582 166 0.028
axon development GO:0061564 96 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
Human
developmental process involved in reproduction GO:0003006 159 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
Human
cellular amine metabolic process GO:0044106 38 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
cellular lipid metabolic process GO:0044255 208 0.027
Mouse
positive regulation of response to stimulus GO:0048584 285 0.026
chemotaxis GO:0006935 66 0.026
multicellular organism reproduction GO:0032504 233 0.026
establishment of tissue polarity GO:0007164 2 0.026
rna biosynthetic process GO:0032774 380 0.026
Human
intracellular signal transduction GO:0035556 314 0.026
synaptic growth at neuromuscular junction GO:0051124 1 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
Human
dendrite development GO:0016358 72 0.025
cellular protein complex assembly GO:0043623 44 0.025
homeostatic process GO:0042592 331 0.025
regulation of response to external stimulus GO:0032101 106 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
lipid metabolic process GO:0006629 283 0.025
Mouse
cellular component morphogenesis GO:0032989 155 0.025
cellular macromolecular complex assembly GO:0034622 58 0.025
regulation of immune system process GO:0002682 123 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
regulation of rna metabolic process GO:0051252 391 0.024
Human
heart morphogenesis GO:0003007 3 0.024
regulation of anatomical structure size GO:0090066 135 0.024
response to estrogen GO:0043627 232 0.024
cell cycle GO:0007049 101 0.024
response to estradiol GO:0032355 164 0.023
regulation of proteasomal protein catabolic process GO:0061136 4 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
positive regulation of developmental process GO:0051094 283 0.022
spindle organization GO:0007051 2 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
reproduction GO:0000003 245 0.022
positive regulation of catalytic activity GO:0043085 184 0.021
glial cell differentiation GO:0010001 65 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
epidermal growth factor receptor signaling pathway GO:0007173 23 0.021
positive regulation of cell death GO:0010942 184 0.021
single organism cellular localization GO:1902580 102 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
behavior GO:0007610 205 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
positive regulation of molecular function GO:0044093 230 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
response to toxic substance GO:0009636 133 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
Human
intracellular transport GO:0046907 185 0.020
regulation of transcription dna templated GO:0006355 374 0.020
Human
regulation of response to stress GO:0080134 126 0.020
regulation of protein metabolic process GO:0051246 289 0.020
positive regulation of cell development GO:0010720 176 0.020
ras protein signal transduction GO:0007265 29 0.020
regulation of cell morphogenesis GO:0022604 77 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
regulation of apoptotic process GO:0042981 335 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
Human
mitotic spindle organization GO:0007052 2 0.020
regulation of growth GO:0040008 105 0.020
regulation of membrane potential GO:0042391 110 0.020
aging GO:0007568 241 0.020
epithelium development GO:0060429 96 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
establishment of protein localization GO:0045184 141 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
negative regulation of signal transduction GO:0009968 83 0.019
developmental growth GO:0048589 100 0.019
regulation of phosphorylation GO:0042325 248 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
negative regulation of cell communication GO:0010648 158 0.019
response to peptide hormone GO:0043434 278 0.019
Mouse
organic acid metabolic process GO:0006082 292 0.019
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
cell part morphogenesis GO:0032990 123 0.019
secretion by cell GO:0032940 248 0.018
response to biotic stimulus GO:0009607 226 0.018
organic substance catabolic process GO:1901575 316 0.018
positive regulation of signaling GO:0023056 270 0.018
vesicle mediated transport GO:0016192 181 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
immune effector process GO:0002252 53 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
negative regulation of phosphate metabolic process GO:0045936 80 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
Human
reproductive structure development GO:0048608 128 0.018
positive regulation of nervous system development GO:0051962 178 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
signal release GO:0023061 145 0.017
protein oligomerization GO:0051259 191 0.017
sexual reproduction GO:0019953 148 0.017
regulation of cellular component size GO:0032535 51 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
regulation of cell growth GO:0001558 85 0.016
protein localization GO:0008104 191 0.016
negative regulation of signaling GO:0023057 157 0.016
response to external biotic stimulus GO:0043207 221 0.016
protein autophosphorylation GO:0046777 66 0.016
biological adhesion GO:0022610 110 0.016
cell growth GO:0016049 104 0.016
cellular catabolic process GO:0044248 295 0.016
reproductive system development GO:0061458 128 0.016
response to inorganic substance GO:0010035 377 0.016
proteolysis GO:0006508 175 0.016
single organism membrane organization GO:0044802 74 0.015
regeneration GO:0031099 163 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
gamete generation GO:0007276 124 0.015
cellular response to external stimulus GO:0071496 118 0.015
cellular chemical homeostasis GO:0055082 247 0.015
single organism catabolic process GO:0044712 283 0.015
negative regulation of molecular function GO:0044092 133 0.015
female pregnancy GO:0007565 122 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
Human
regulation of protein modification process GO:0031399 194 0.015
protein transport GO:0015031 132 0.015
vesicle localization GO:0051648 33 0.015
transmembrane transport GO:0055085 412 0.015
response to ketone GO:1901654 182 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
endocytosis GO:0006897 84 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
erythrocyte differentiation GO:0030218 1 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
macromolecule localization GO:0033036 252 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
multi multicellular organism process GO:0044706 138 0.014
ion transmembrane transport GO:0034220 365 0.014
inflammatory response GO:0006954 150 0.014
regulation of dendrite development GO:0050773 59 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
regulation of protein complex assembly GO:0043254 33 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
epithelial cell differentiation GO:0030855 71 0.014
positive regulation of cell communication GO:0010647 271 0.014
axon guidance GO:0007411 24 0.013
cellular macromolecule localization GO:0070727 122 0.013
chemical homeostasis GO:0048878 292 0.013
blood circulation GO:0008015 183 0.013
lymphocyte homeostasis GO:0002260 2 0.013
wound healing GO:0042060 122 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
synaptic vesicle endocytosis GO:0048488 4 0.013
cation homeostasis GO:0055080 195 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
purine containing compound metabolic process GO:0072521 253 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
endomembrane system organization GO:0010256 48 0.013
regulation of hydrolase activity GO:0051336 143 0.013
response to corticosteroid GO:0031960 235 0.013
cellular homeostasis GO:0019725 252 0.013
blood vessel development GO:0001568 69 0.013
positive regulation of protein modification process GO:0031401 142 0.013
cellular response to hormone stimulus GO:0032870 247 0.012
response to axon injury GO:0048678 59 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
circulatory system development GO:0072359 134 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
organophosphate metabolic process GO:0019637 370 0.012
membrane organization GO:0061024 94 0.012
eye morphogenesis GO:0048592 4 0.012
metal ion transport GO:0030001 289 0.012
response to glucocorticoid GO:0051384 223 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
intracellular protein transport GO:0006886 79 0.012
organ morphogenesis GO:0009887 75 0.012
ion homeostasis GO:0050801 212 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
response to extracellular stimulus GO:0009991 380 0.012
defense response GO:0006952 194 0.012
regulation of cellular localization GO:0060341 263 0.012
neuronal action potential GO:0019228 35 0.012
anion transport GO:0006820 178 0.012
nitrogen compound transport GO:0071705 229 0.012
response to ethanol GO:0045471 162 0.012
organelle localization GO:0051640 55 0.012
positive regulation of gene expression GO:0010628 244 0.012
Human
negative regulation of cell proliferation GO:0008285 119 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of dna metabolic process GO:0051052 60 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
regulation of immune response GO:0050776 55 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
response to hexose GO:0009746 144 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
transmission of nerve impulse GO:0019226 42 0.011
cellular protein localization GO:0034613 122 0.011
actin cytoskeleton organization GO:0030036 73 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
response to peptide GO:1901652 292 0.011
Mouse
regulation of catabolic process GO:0009894 113 0.011
dna metabolic process GO:0006259 96 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
cell cycle process GO:0022402 57 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
organic anion transport GO:0015711 132 0.011
cell fate determination GO:0001709 2 0.011
cell type specific apoptotic process GO:0097285 134 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
response to carbohydrate GO:0009743 183 0.011
forebrain development GO:0030900 98 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
sex differentiation GO:0007548 113 0.011
actin filament based process GO:0030029 86 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
regulation of protein kinase activity GO:0045859 105 0.011
response to nutrient GO:0007584 248 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
response to glucose GO:0009749 136 0.011
protein processing GO:0016485 68 0.011
regulation of cellular response to stress GO:0080135 49 0.011
response to oxidative stress GO:0006979 186 0.011
nucleotide metabolic process GO:0009117 279 0.011
axis specification GO:0009798 4 0.011
regulation of actin filament based process GO:0032970 42 0.011
regulation of lipid biosynthetic process GO:0046890 38 0.011
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
Human
eye development GO:0001654 50 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
lipid transport GO:0006869 61 0.010
response to amino acid GO:0043200 75 0.010
myoblast fusion GO:0007520 2 0.010
neuron projection guidance GO:0097485 24 0.010
regulation of immunoglobulin production GO:0002637 4 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
positive regulation of transcription factor import into nucleus GO:0042993 4 0.010

Scap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of cellular proliferation DOID:14566 0 0.023
cancer DOID:162 0 0.019
organ system cancer DOID:0050686 0 0.019
central nervous system disease DOID:331 0 0.011
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010