Rattus norvegicus

22 known processes

Mst1

Macrophage stimulating 1 (hepatocyte growth factor-like)

(Aliases: E2F2)

Mst1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.198
Rat
response to extracellular stimulus GO:0009991 380 0.177
response to nutrient levels GO:0031667 370 0.165
response to peptide GO:1901652 292 0.163
Rat
regulation of transcription dna templated GO:0006355 374 0.163
response to acid chemical GO:0001101 222 0.156
negative regulation of multicellular organismal process GO:0051241 203 0.152
response to biotic stimulus GO:0009607 226 0.151
Rat
cellular response to nitrogen compound GO:1901699 210 0.148
Rat
regulation of programmed cell death GO:0043067 341 0.131
Rat
regulation of rna metabolic process GO:0051252 391 0.127
regulation of nucleic acid templated transcription GO:1903506 380 0.115
regulation of secretion by cell GO:1903530 208 0.112
cellular response to oxygen containing compound GO:1901701 386 0.111
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.111
rna metabolic process GO:0016070 406 0.109
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.106
response to estrogen GO:0043627 232 0.105
rna biosynthetic process GO:0032774 380 0.103
single organism reproductive process GO:0044702 297 0.099
amine metabolic process GO:0009308 38 0.099
response to insulin GO:0032868 133 0.095
macromolecular complex subunit organization GO:0043933 339 0.094
response to peptide hormone GO:0043434 278 0.089
Rat
carboxylic acid metabolic process GO:0019752 289 0.089
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.088
regulation of cellular ketone metabolic process GO:0010565 27 0.086
response to inorganic substance GO:0010035 377 0.083
rhythmic process GO:0048511 156 0.080
protein complex biogenesis GO:0070271 263 0.078
cellular component biogenesis GO:0044085 368 0.078
regulation of rna biosynthetic process GO:2001141 381 0.074
regulation of phosphorus metabolic process GO:0051174 349 0.073
regulation of multicellular organismal development GO:2000026 376 0.072
Rat
negative regulation of biosynthetic process GO:0009890 168 0.072
negative regulation of nucleic acid templated transcription GO:1903507 117 0.071
nucleic acid templated transcription GO:0097659 379 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.070
negative regulation of immune system process GO:0002683 39 0.070
macromolecular complex assembly GO:0065003 273 0.070
lipid biosynthetic process GO:0008610 128 0.069
cellular response to endogenous stimulus GO:0071495 377 0.068
Rat
regulation of cell development GO:0060284 263 0.068
Rat
positive regulation of biosynthetic process GO:0009891 319 0.068
response to nutrient GO:0007584 248 0.067
negative regulation of metabolic process GO:0009892 331 0.066
negative regulation of rna metabolic process GO:0051253 123 0.066
cellular amino acid metabolic process GO:0006520 107 0.066
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.066
response to wounding GO:0009611 254 0.065
Rat
cellular amine metabolic process GO:0044106 38 0.065
regulation of molecular function GO:0065009 398 0.064
response to lipopolysaccharide GO:0032496 191 0.063
Rat
tissue development GO:0009888 252 0.062
Zebrafish Rat
reproduction GO:0000003 245 0.060
vesicle mediated transport GO:0016192 181 0.059
positive regulation of rna metabolic process GO:0051254 203 0.059
positive regulation of developmental process GO:0051094 283 0.057
Rat
organic acid metabolic process GO:0006082 292 0.057
catabolic process GO:0009056 351 0.056
Rat
transcription dna templated GO:0006351 377 0.056
regulation of apoptotic process GO:0042981 335 0.056
Rat
positive regulation of gene expression GO:0010628 244 0.055
protein oligomerization GO:0051259 191 0.054
regulation of hydrolase activity GO:0051336 143 0.051
apoptotic process GO:0006915 381 0.051
Rat
regulation of signal transduction GO:0009966 318 0.051
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.051
regeneration GO:0031099 163 0.051
Rat
regulation of catalytic activity GO:0050790 304 0.051
reactive nitrogen species metabolic process GO:2001057 1 0.050
cellular ketone metabolic process GO:0042180 51 0.050
regulation of cellular localization GO:0060341 263 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.049
positive regulation of cell death GO:0010942 184 0.049
negative regulation of macromolecule metabolic process GO:0010605 260 0.049
cellular response to hormone stimulus GO:0032870 247 0.048
Rat
coenzyme metabolic process GO:0006732 86 0.048
negative regulation of cell differentiation GO:0045596 99 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.047
negative regulation of developmental process GO:0051093 125 0.047
cellular component assembly GO:0022607 360 0.047
growth GO:0040007 165 0.046
Rat
positive regulation of transport GO:0051050 245 0.046
cofactor metabolic process GO:0051186 95 0.046
secretion GO:0046903 307 0.046
cellular response to organonitrogen compound GO:0071417 197 0.046
Rat
regulation of secretion GO:0051046 224 0.045
nucleobase containing small molecule metabolic process GO:0055086 316 0.045
protein complex assembly GO:0006461 263 0.044
regulation of cellular component organization GO:0051128 368 0.044
Rat
reproductive process GO:0022414 372 0.044
cellular response to steroid hormone stimulus GO:0071383 93 0.044
Rat
response to purine containing compound GO:0014074 126 0.044
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.043
regulation of cellular amino acid metabolic process GO:0006521 2 0.043
negative regulation of programmed cell death GO:0043069 183 0.042
Rat
proteolysis GO:0006508 175 0.042
Rat
positive regulation of response to stimulus GO:0048584 285 0.042
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.041
immune response GO:0006955 104 0.041
protein complex subunit organization GO:0071822 302 0.041
negative regulation of transcription dna templated GO:0045892 116 0.041
single organism biosynthetic process GO:0044711 342 0.040
synaptic transmission GO:0007268 235 0.040
Rat
protein localization GO:0008104 191 0.040
negative regulation of signaling GO:0023057 157 0.040
regulation of protein metabolic process GO:0051246 289 0.039
jak stat cascade GO:0007259 26 0.039
positive regulation of cellular component organization GO:0051130 200 0.038
Rat
intracellular signal transduction GO:0035556 314 0.038
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
response to growth factor GO:0070848 189 0.037
Rat
multi organism reproductive process GO:0044703 262 0.037
immune system process GO:0002376 204 0.037
positive regulation of programmed cell death GO:0043068 157 0.037
regulation of phosphorylation GO:0042325 248 0.036
cellular component movement GO:0006928 248 0.036
response to transition metal nanoparticle GO:1990267 122 0.036
positive regulation of rna biosynthetic process GO:1902680 197 0.036
positive regulation of cell differentiation GO:0045597 217 0.036
Rat
regulation of cell differentiation GO:0045595 320 0.036
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.035
transmission of nerve impulse GO:0019226 42 0.035
organic substance catabolic process GO:1901575 316 0.035
Rat
oxoacid metabolic process GO:0043436 290 0.035
response to decreased oxygen levels GO:0036293 237 0.035
Rat
aging GO:0007568 241 0.035
cellular response to organic cyclic compound GO:0071407 202 0.035
Rat
protein phosphorylation GO:0006468 345 0.034
establishment of protein localization GO:0045184 141 0.034
negative regulation of rna biosynthetic process GO:1902679 118 0.034
negative regulation of gene expression GO:0010629 199 0.034
response to corticosteroid GO:0031960 235 0.033
Rat
response to mechanical stimulus GO:0009612 134 0.033
monosaccharide metabolic process GO:0005996 61 0.033
cellular response to stress GO:0033554 269 0.033
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
small molecule catabolic process GO:0044282 59 0.032
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.032
negative regulation of cell proliferation GO:0008285 119 0.032
response to other organism GO:0051707 220 0.032
Rat
multicellular organism reproduction GO:0032504 233 0.032
cellular response to peptide GO:1901653 133 0.032
negative regulation of apoptotic process GO:0043066 181 0.032
Rat
mesoderm development GO:0007498 2 0.032
positive regulation of transcription dna templated GO:0045893 197 0.031
regulation of synaptic transmission GO:0050804 141 0.031
Rat
circulatory system development GO:0072359 134 0.031
Rat
positive regulation of signaling GO:0023056 270 0.031
cellular response to external stimulus GO:0071496 118 0.031
regulation of phosphate metabolic process GO:0019220 349 0.030
regulation of protein phosphorylation GO:0001932 183 0.030
regulation of cell motility GO:2000145 131 0.030
Rat
anatomical structure morphogenesis GO:0009653 298 0.030
Rat
hexose metabolic process GO:0019318 58 0.030
cellular response to acid chemical GO:0071229 75 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.029
regulation of neurogenesis GO:0050767 247 0.029
Rat
metal ion transport GO:0030001 289 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
anion transport GO:0006820 178 0.028
response to glucocorticoid GO:0051384 223 0.028
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.028
Rat
negative regulation of cell communication GO:0010648 158 0.028
immunoglobulin mediated immune response GO:0016064 4 0.027
regulation of immune system process GO:0002682 123 0.027
response to cytokine GO:0034097 215 0.027
innate immune response GO:0045087 35 0.027
cell projection organization GO:0030030 302 0.026
Rat
response to metal ion GO:0010038 253 0.026
response to estradiol GO:0032355 164 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
circadian rhythm GO:0007623 88 0.025
aromatic compound catabolic process GO:0019439 168 0.025
carboxylic acid catabolic process GO:0046395 49 0.025
wound healing GO:0042060 122 0.025
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
negative regulation of serine type endopeptidase activity GO:1900004 1 0.024
cellular response to insulin stimulus GO:0032869 81 0.024
negative regulation of molecular function GO:0044092 133 0.024
regulation of stem cell differentiation GO:2000736 2 0.024
purine containing compound metabolic process GO:0072521 253 0.024
glucose metabolic process GO:0006006 52 0.024
multicellular organismal signaling GO:0035637 44 0.024
positive regulation of immune response GO:0050778 42 0.024
regulation of growth GO:0040008 105 0.023
transmembrane transport GO:0055085 412 0.023
gamete generation GO:0007276 124 0.023
organelle organization GO:0006996 266 0.023
response to ethanol GO:0045471 162 0.023
homeostatic process GO:0042592 331 0.023
Rat
response to external biotic stimulus GO:0043207 221 0.023
Rat
regulation of response to stress GO:0080134 126 0.023
Rat
reactive oxygen species metabolic process GO:0072593 37 0.023
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
negative regulation of cell death GO:0060548 229 0.022
Rat
positive regulation of molecular function GO:0044093 230 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
cellular lipid metabolic process GO:0044255 208 0.022
intracellular protein transport GO:0006886 79 0.022
positive regulation of protein modification process GO:0031401 142 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
positive regulation of cell communication GO:0010647 271 0.022
regulation of immune response GO:0050776 55 0.022
regulation of epithelial cell proliferation GO:0050678 49 0.022
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.022
response to amino acid GO:0043200 75 0.022
macromolecule localization GO:0033036 252 0.022
regulation of renal sodium excretion GO:0035813 20 0.021
b cell mediated immunity GO:0019724 4 0.021
sexual reproduction GO:0019953 148 0.020
cellular response to molecule of bacterial origin GO:0071219 56 0.020
Rat
regulation of cell proliferation GO:0042127 359 0.020
Rat
regulation of system process GO:0044057 208 0.020
Rat
protein homooligomerization GO:0051260 91 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
reactive oxygen species biosynthetic process GO:1903409 8 0.020
positive regulation of nervous system development GO:0051962 178 0.020
Rat
positive regulation of hepatocyte differentiation GO:0070368 2 0.020
glial cell differentiation GO:0010001 65 0.020
single organism organelle organization GO:1902589 180 0.020
neuron differentiation GO:0030182 368 0.020
Rat
response to vitamin GO:0033273 131 0.020
positive regulation of kinase activity GO:0033674 77 0.019
lipid metabolic process GO:0006629 283 0.019
defense response GO:0006952 194 0.019
glycerolipid metabolic process GO:0046486 67 0.019
regulation of transferase activity GO:0051338 123 0.019
negative regulation of cell development GO:0010721 82 0.019
response to hypoxia GO:0001666 231 0.019
Rat
signal transduction by phosphorylation GO:0023014 144 0.019
organophosphate metabolic process GO:0019637 370 0.019
head development GO:0060322 247 0.019
negative regulation of catalytic activity GO:0043086 103 0.019
ion transmembrane transport GO:0034220 365 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
cell adhesion GO:0007155 110 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
Rat
regulation of protein modification process GO:0031399 194 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
spermatogenesis GO:0007283 99 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
peptidyl amino acid modification GO:0018193 126 0.018
meiotic cell cycle process GO:1903046 3 0.018
positive regulation of secretion GO:0051047 140 0.018
multicellular organism growth GO:0035264 1 0.018
neuron development GO:0048666 286 0.017
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
Rat
positive regulation of signal transduction GO:0009967 175 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
Rat
negative regulation of secretion by cell GO:1903531 72 0.017
acetyl coa metabolic process GO:0006084 17 0.017
carboxylic acid transport GO:0046942 115 0.017
response to fatty acid GO:0070542 65 0.017
b cell activation involved in immune response GO:0002312 1 0.017
nuclear import GO:0051170 35 0.017
secretion by cell GO:0032940 248 0.016
dna metabolic process GO:0006259 96 0.016
protein tetramerization GO:0051262 38 0.016
negative regulation of growth GO:0045926 37 0.016
single organism intracellular transport GO:1902582 166 0.016
negative regulation of secretion GO:0051048 82 0.016
nucleotide metabolic process GO:0009117 279 0.016
cellular macromolecule localization GO:0070727 122 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
positive regulation of cell development GO:0010720 176 0.016
Rat
biological adhesion GO:0022610 110 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
cholesterol homeostasis GO:0042632 3 0.016
single organism catabolic process GO:0044712 283 0.016
cytoplasmic transport GO:0016482 115 0.016
regulation of response to external stimulus GO:0032101 106 0.016
brain development GO:0007420 247 0.016
sterol homeostasis GO:0055092 3 0.016
neurological system process GO:0050877 219 0.016
Rat
carbohydrate homeostasis GO:0033500 75 0.016
Rat
calcium ion transport GO:0006816 131 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
regulation of cytokine biosynthetic process GO:0042035 3 0.016
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
Rat
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of serine type endopeptidase activity GO:1900003 1 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
Rat
central nervous system development GO:0007417 311 0.015
response to oxygen levels GO:0070482 265 0.015
Rat
positive regulation of neurogenesis GO:0050769 165 0.015
Rat
gland development GO:0048732 155 0.015
Rat
regulation of nervous system development GO:0051960 264 0.015
Rat
response to triglyceride GO:0034014 3 0.015
cardiovascular system development GO:0072358 134 0.015
Rat
regulation of proteolysis GO:0030162 66 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
protein targeting GO:0006605 61 0.015
positive regulation of immunoglobulin production GO:0002639 4 0.015
appendage morphogenesis GO:0035107 4 0.015
regulation of kinase activity GO:0043549 117 0.015
response to organophosphorus GO:0046683 102 0.015
Rat
chemical homeostasis GO:0048878 292 0.014
Rat
heart morphogenesis GO:0003007 3 0.014
tissue regeneration GO:0042246 36 0.014
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
Rat
cognition GO:0050890 92 0.014
nuclear transport GO:0051169 49 0.014
cation transport GO:0006812 382 0.014
endocytosis GO:0006897 84 0.014
alcohol metabolic process GO:0006066 77 0.014
response to bacterium GO:0009617 200 0.014
Rat
regulation of response to wounding GO:1903034 69 0.014
locomotion GO:0040011 237 0.014
epithelial cell differentiation GO:0030855 71 0.014
gastrulation GO:0007369 2 0.014
negative regulation of serine type peptidase activity GO:1902572 1 0.014
organ regeneration GO:0031100 101 0.014
Rat
response to fluoride GO:1902617 3 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
organic acid catabolic process GO:0016054 49 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
epithelial cell proliferation GO:0050673 54 0.014
Rat
sulfur compound metabolic process GO:0006790 70 0.014
male gamete generation GO:0048232 99 0.014
cellular biogenic amine metabolic process GO:0006576 30 0.014
acyl coa metabolic process GO:0006637 28 0.013
regulation of peptide transport GO:0090087 87 0.013
exocytosis GO:0006887 60 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
muscle cell proliferation GO:0033002 84 0.013
negative regulation of cytokine production GO:0001818 16 0.013
aromatic amino acid family catabolic process GO:0009074 7 0.013
hormone metabolic process GO:0042445 69 0.013
regulation of ion homeostasis GO:2000021 63 0.013
peptidyl tyrosine modification GO:0018212 72 0.013
negative regulation of innate immune response GO:0045824 4 0.013
protein targeting to nucleus GO:0044744 35 0.013
negative regulation of nervous system development GO:0051961 79 0.013
chemosensory behavior GO:0007635 2 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
ion homeostasis GO:0050801 212 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of immunoglobulin production GO:0002637 4 0.013
developmental process involved in reproduction GO:0003006 159 0.013
hepatocyte proliferation GO:0072574 3 0.013
Rat
cellular response to fluid shear stress GO:0071498 4 0.013
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.012
ovulation cycle GO:0042698 67 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
cell cell signaling GO:0007267 335 0.012
Rat
neuronal action potential GO:0019228 35 0.012
nitrogen compound transport GO:0071705 229 0.012
olfactory learning GO:0008355 1 0.012
response to oxidative stress GO:0006979 186 0.012
response to light stimulus GO:0009416 52 0.012
protein localization to nucleus GO:0034504 39 0.012
regulation of jak stat cascade GO:0046425 21 0.012
respiratory system development GO:0060541 45 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of neurological system process GO:0031644 43 0.012
Rat
neuron projection development GO:0031175 273 0.012
Rat
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of serine type peptidase activity GO:1902571 1 0.012
cell type specific apoptotic process GO:0097285 134 0.012
chromosome segregation GO:0007059 2 0.012
lymphocyte mediated immunity GO:0002449 14 0.012
oxidation reduction process GO:0055114 304 0.012
regulation of protein processing GO:0070613 50 0.012
response to calcium ion GO:0051592 59 0.012
response to radiation GO:0009314 137 0.012
muscle structure development GO:0061061 87 0.012
response to chromate GO:0046687 3 0.012
cellular response to lipid GO:0071396 201 0.012
Rat
neuron death GO:0070997 127 0.011
Rat
regulation of ion transport GO:0043269 245 0.011
cellular protein localization GO:0034613 122 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
immune effector process GO:0002252 53 0.011
negative regulation of peptidase activity GO:0010466 38 0.011
behavior GO:0007610 205 0.011
regulation of immunoglobulin mediated immune response GO:0002889 2 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
epithelium development GO:0060429 96 0.011
regulation of cell cycle GO:0051726 73 0.011
response to vitamin k GO:0032571 4 0.011
response to hexose GO:0009746 144 0.011
Rat
response to camp GO:0051591 91 0.011
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
Rat
cellular component morphogenesis GO:0032989 155 0.011
positive regulation of epithelial cell proliferation GO:0050679 32 0.011
thioester metabolic process GO:0035383 28 0.011
sulfur amino acid metabolic process GO:0000096 9 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
Rat
liver development GO:0001889 90 0.010
Rat
regulation of vesicle mediated transport GO:0060627 81 0.010
lipid storage GO:0019915 1 0.010
regulation of epithelial to mesenchymal transition GO:0010717 2 0.010
response to alkaloid GO:0043279 132 0.010
Rat
alpha amino acid metabolic process GO:1901605 71 0.010
regulation of peptidase activity GO:0052547 55 0.010
positive regulation of transferase activity GO:0051347 81 0.010
protein import into nucleus GO:0006606 35 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.010
protein transport GO:0015031 132 0.010
positive regulation of immune system process GO:0002684 90 0.010
negative regulation of protein maturation GO:1903318 47 0.010
olfactory behavior GO:0042048 2 0.010
fatty acid metabolic process GO:0006631 99 0.010

Mst1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
musculoskeletal system disease DOID:17 0 0.026
disease of metabolism DOID:0014667 0 0.017