Rattus norvegicus

0 known processes

Chic2

cysteine-rich hydrophobic domain 2

Chic2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.087
rna biosynthetic process GO:0032774 380 0.070
regulation of rna metabolic process GO:0051252 391 0.068
neuron development GO:0048666 286 0.064
cell projection organization GO:0030030 302 0.060
positive regulation of response to stimulus GO:0048584 285 0.057
rna metabolic process GO:0016070 406 0.057
transcription dna templated GO:0006351 377 0.057
regulation of rna biosynthetic process GO:2001141 381 0.054
regulation of neuron differentiation GO:0045664 208 0.051
neuron differentiation GO:0030182 368 0.050
regulation of cell differentiation GO:0045595 320 0.049
regulation of neurogenesis GO:0050767 247 0.043
regulation of transcription dna templated GO:0006355 374 0.041
positive regulation of signaling GO:0023056 270 0.041
regulation of cell projection organization GO:0031344 175 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
regulation of protein modification process GO:0031399 194 0.039
carboxylic acid metabolic process GO:0019752 289 0.038
nucleic acid templated transcription GO:0097659 379 0.038
protein phosphorylation GO:0006468 345 0.038
negative regulation of metabolic process GO:0009892 331 0.037
neuron projection development GO:0031175 273 0.037
intracellular signal transduction GO:0035556 314 0.037
regulation of molecular function GO:0065009 398 0.036
regulation of cell development GO:0060284 263 0.036
regulation of protein metabolic process GO:0051246 289 0.035
positive regulation of neuron differentiation GO:0045666 126 0.035
regulation of intracellular signal transduction GO:1902531 218 0.035
secretion GO:0046903 307 0.034
positive regulation of cell communication GO:0010647 271 0.034
secretion by cell GO:0032940 248 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.033
programmed cell death GO:0012501 392 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
organelle organization GO:0006996 266 0.032
protein localization GO:0008104 191 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.031
cellular component biogenesis GO:0044085 368 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
multicellular organism reproduction GO:0032504 233 0.031
single organism organelle organization GO:1902589 180 0.031
protein complex subunit organization GO:0071822 302 0.031
regulation of secretion by cell GO:1903530 208 0.030
regulation of neuron projection development GO:0010975 161 0.030
positive regulation of developmental process GO:0051094 283 0.030
regulation of response to stress GO:0080134 126 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.029
reproductive process GO:0022414 372 0.029
regulation of nervous system development GO:0051960 264 0.029
oxoacid metabolic process GO:0043436 290 0.029
multi organism reproductive process GO:0044703 262 0.029
single organism reproductive process GO:0044702 297 0.029
cation transport GO:0006812 382 0.029
organophosphate metabolic process GO:0019637 370 0.029
cellular catabolic process GO:0044248 295 0.029
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
cellular amine metabolic process GO:0044106 38 0.028
positive regulation of nervous system development GO:0051962 178 0.028
cellular response to oxygen containing compound GO:1901701 386 0.027
regulation of signal transduction GO:0009966 318 0.027
reproduction GO:0000003 245 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
amine metabolic process GO:0009308 38 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.026
cellular component movement GO:0006928 248 0.026
apoptotic process GO:0006915 381 0.026
regulation of immune system process GO:0002682 123 0.026
organic acid metabolic process GO:0006082 292 0.025
regulation of cell proliferation GO:0042127 359 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
response to inorganic substance GO:0010035 377 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.025
negative regulation of cell death GO:0060548 229 0.024
neuron death GO:0070997 127 0.024
cellular component assembly GO:0022607 360 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
regulation of catalytic activity GO:0050790 304 0.024
cellular cation homeostasis GO:0030003 180 0.024
response to oxidative stress GO:0006979 186 0.024
cellular ketone metabolic process GO:0042180 51 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
response to peptide hormone GO:0043434 278 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
nitrogen compound transport GO:0071705 229 0.023
positive regulation of neuron projection development GO:0010976 99 0.023
response to extracellular stimulus GO:0009991 380 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
behavior GO:0007610 205 0.023
response to biotic stimulus GO:0009607 226 0.023
negative regulation of transport GO:0051051 136 0.023
cell adhesion GO:0007155 110 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.022
positive regulation of molecular function GO:0044093 230 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
single organism biosynthetic process GO:0044711 342 0.022
immune system process GO:0002376 204 0.022
tissue development GO:0009888 252 0.022
ion homeostasis GO:0050801 212 0.022
homeostatic process GO:0042592 331 0.022
negative regulation of gene expression GO:0010629 199 0.022
macromolecule localization GO:0033036 252 0.022
cellular response to lipid GO:0071396 201 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
positive regulation of transport GO:0051050 245 0.022
cation homeostasis GO:0055080 195 0.022
positive regulation of cell differentiation GO:0045597 217 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
protein complex assembly GO:0006461 263 0.021
regulation of phosphorylation GO:0042325 248 0.021
catabolic process GO:0009056 351 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
regulation of programmed cell death GO:0043067 341 0.021
ras protein signal transduction GO:0007265 29 0.021
negative regulation of cell communication GO:0010648 158 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
positive regulation of cell development GO:0010720 176 0.020
regulation of phosphate metabolic process GO:0019220 349 0.020
locomotion GO:0040011 237 0.020
chemical homeostasis GO:0048878 292 0.020
macromolecular complex assembly GO:0065003 273 0.020
aging GO:0007568 241 0.020
positive regulation of signal transduction GO:0009967 175 0.020
response to mechanical stimulus GO:0009612 134 0.020
cellular homeostasis GO:0019725 252 0.019
response to peptide GO:1901652 292 0.019
regulation of apoptotic process GO:0042981 335 0.019
cell morphogenesis GO:0000902 142 0.019
cell migration GO:0016477 197 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
regulation of cellular localization GO:0060341 263 0.019
response to acid chemical GO:0001101 222 0.019
negative regulation of developmental process GO:0051093 125 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
cellular response to stress GO:0033554 269 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
response to wounding GO:0009611 254 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
response to nutrient levels GO:0031667 370 0.018
response to estrogen GO:0043627 232 0.018
protein complex biogenesis GO:0070271 263 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
sexual reproduction GO:0019953 148 0.018
cellular chemical homeostasis GO:0055082 247 0.018
cellular ion homeostasis GO:0006873 184 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
organic substance catabolic process GO:1901575 316 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
positive regulation of gene expression GO:0010628 244 0.017
nucleotide metabolic process GO:0009117 279 0.017
response to external biotic stimulus GO:0043207 221 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
regulation of neuron death GO:1901214 115 0.017
single organism intracellular transport GO:1902582 166 0.017
regulation of secretion GO:0051046 224 0.017
purine containing compound metabolic process GO:0072521 253 0.017
metal ion homeostasis GO:0055065 186 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
axis specification GO:0009798 4 0.017
regulation of membrane potential GO:0042391 110 0.016
intracellular transport GO:0046907 185 0.016
central nervous system development GO:0007417 311 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
regulation of locomotion GO:0040012 148 0.016
lipid metabolic process GO:0006629 283 0.016
regulation of cell motility GO:2000145 131 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
calcium ion homeostasis GO:0055074 162 0.016
gamete generation GO:0007276 124 0.016
vesicle mediated transport GO:0016192 181 0.016
localization of cell GO:0051674 202 0.016
negative regulation of cell differentiation GO:0045596 99 0.016
response to nutrient GO:0007584 248 0.016
metal ion transport GO:0030001 289 0.016
growth GO:0040007 165 0.015
cell part morphogenesis GO:0032990 123 0.015
gastrulation GO:0007369 2 0.015
negative regulation of signaling GO:0023057 157 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of response to external stimulus GO:0032101 106 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
cellular component morphogenesis GO:0032989 155 0.015
embryonic pattern specification GO:0009880 1 0.015
response to organophosphorus GO:0046683 102 0.014
biological adhesion GO:0022610 110 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular protein localization GO:0034613 122 0.014
response to glucocorticoid GO:0051384 223 0.014
brain development GO:0007420 247 0.014
dna metabolic process GO:0006259 96 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
chromosome segregation GO:0007059 2 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cell type specific apoptotic process GO:0097285 134 0.014
regulation of system process GO:0044057 208 0.014
positive regulation of protein modification process GO:0031401 142 0.014
response to corticosteroid GO:0031960 235 0.014
regulation of ion transport GO:0043269 245 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
spindle organization GO:0007051 2 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
proteolysis GO:0006508 175 0.014
positive regulation of catalytic activity GO:0043085 184 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
wound healing GO:0042060 122 0.013
regulation of hydrolase activity GO:0051336 143 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
neuron apoptotic process GO:0051402 88 0.013
signal release GO:0023061 145 0.013
gliogenesis GO:0042063 93 0.013
cell projection morphogenesis GO:0048858 123 0.013
response to metal ion GO:0010038 253 0.013
response to reactive oxygen species GO:0000302 120 0.013
neurological system process GO:0050877 219 0.013
establishment of protein localization GO:0045184 141 0.013
developmental growth GO:0048589 100 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
cell motility GO:0048870 202 0.013
cardiovascular system development GO:0072358 134 0.013
positive regulation of immune system process GO:0002684 90 0.013
peptide hormone secretion GO:0030072 84 0.013
cell cell signaling GO:0007267 335 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
response to other organism GO:0051707 220 0.013
eye morphogenesis GO:0048592 4 0.013
cytoskeleton organization GO:0007010 111 0.012
carbohydrate metabolic process GO:0005975 130 0.012
nucleoside metabolic process GO:0009116 179 0.012
dephosphorylation GO:0016311 98 0.012
heart morphogenesis GO:0003007 3 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of secretion GO:0051047 140 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
response to ketone GO:1901654 182 0.012
regulation of catabolic process GO:0009894 113 0.012
response to hypoxia GO:0001666 231 0.012
regulation of organelle organization GO:0033043 80 0.012
developmental process involved in reproduction GO:0003006 159 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
amide transport GO:0042886 105 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
actin filament based process GO:0030029 86 0.012
maintenance of location GO:0051235 17 0.012
regulation of hormone levels GO:0010817 187 0.012
positive regulation of cell death GO:0010942 184 0.012
peptide secretion GO:0002790 86 0.012
response to growth factor GO:0070848 189 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
membrane organization GO:0061024 94 0.011
response to oxygen levels GO:0070482 265 0.011
regulation of cell migration GO:0030334 128 0.011
spermatogenesis GO:0007283 99 0.011
cellular macromolecule localization GO:0070727 122 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
head development GO:0060322 247 0.011
defense response GO:0006952 194 0.011
regulation of protein transport GO:0051223 68 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
response to radiation GO:0009314 137 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
ion transmembrane transport GO:0034220 365 0.011
tube development GO:0035295 89 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
male gamete generation GO:0048232 99 0.011
circulatory system development GO:0072359 134 0.011
transmembrane transport GO:0055085 412 0.011
organophosphate catabolic process GO:0046434 148 0.011
cellular lipid metabolic process GO:0044255 208 0.011
regulation of defense response GO:0031347 68 0.011
hormone secretion GO:0046879 115 0.011
glial cell differentiation GO:0010001 65 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
response to ethanol GO:0045471 162 0.010
meiotic cell cycle process GO:1903046 3 0.010
positive regulation of cell migration GO:0030335 96 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
negative regulation of innate immune response GO:0045824 4 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
response to carbohydrate GO:0009743 183 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
mapk cascade GO:0000165 140 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
cell activation GO:0001775 97 0.010
lipid storage GO:0019915 1 0.010
response to bacterium GO:0009617 200 0.010

Chic2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.012
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010