Rattus norvegicus

7 known processes

Sfrp2

secreted frizzled-related protein 2

Sfrp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to hypoxia GO:0001666 231 0.107
non canonical wnt signaling pathway GO:0035567 3 0.082
regulation of cellular component organization GO:0051128 368 0.076
Human
positive regulation of response to stimulus GO:0048584 285 0.073
neuron differentiation GO:0030182 368 0.063
response to corticosteroid GO:0031960 235 0.059
negative regulation of signaling GO:0023057 157 0.059
Human Rat
reproductive process GO:0022414 372 0.059
gland development GO:0048732 155 0.057
macromolecule localization GO:0033036 252 0.056
response to nutrient GO:0007584 248 0.052
cellular component movement GO:0006928 248 0.052
positive regulation of cell communication GO:0010647 271 0.049
regulation of multicellular organismal development GO:2000026 376 0.049
Human Rat
response to wounding GO:0009611 254 0.049
response to decreased oxygen levels GO:0036293 237 0.048
organic acid metabolic process GO:0006082 292 0.048
response to nutrient levels GO:0031667 370 0.047
blood circulation GO:0008015 183 0.044
central nervous system development GO:0007417 311 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
Human
positive regulation of developmental process GO:0051094 283 0.043
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.041
nucleotide metabolic process GO:0009117 279 0.041
nucleic acid templated transcription GO:0097659 379 0.041
Human
tissue development GO:0009888 252 0.040
Human
single organism reproductive process GO:0044702 297 0.040
protein localization GO:0008104 191 0.038
regulation of programmed cell death GO:0043067 341 0.038
Human
response to oxygen levels GO:0070482 265 0.037
neuron development GO:0048666 286 0.037
cellular response to stress GO:0033554 269 0.037
regulation of catalytic activity GO:0050790 304 0.037
regulation of cellular localization GO:0060341 263 0.036
negative regulation of signal transduction GO:0009968 83 0.036
Human Rat
head development GO:0060322 247 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.035
divalent metal ion transport GO:0070838 132 0.035
rna biosynthetic process GO:0032774 380 0.035
Human
positive regulation of signal transduction GO:0009967 175 0.035
regulation of immune system process GO:0002682 123 0.034
Rat
regulation of canonical wnt signaling pathway GO:0060828 4 0.034
Human Rat
regulation of phosphorylation GO:0042325 248 0.033
response to glucocorticoid GO:0051384 223 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
tissue remodeling GO:0048771 40 0.031
regulation of anatomical structure morphogenesis GO:0022603 141 0.031
Human
purine nucleotide metabolic process GO:0006163 229 0.031
connective tissue development GO:0061448 33 0.031
regeneration GO:0031099 163 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
regulation of apoptotic process GO:0042981 335 0.030
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
cellular component biogenesis GO:0044085 368 0.029
organ morphogenesis GO:0009887 75 0.029
Human
amine metabolic process GO:0009308 38 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
secretion by cell GO:0032940 248 0.029
regulation of cell proliferation GO:0042127 359 0.029
Human
apoptotic process GO:0006915 381 0.028
Human
cardiovascular system development GO:0072358 134 0.028
Human
localization of cell GO:0051674 202 0.028
multi organism reproductive process GO:0044703 262 0.028
calcium ion transport GO:0006816 131 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
kidney development GO:0001822 67 0.028
regulation of rna metabolic process GO:0051252 391 0.028
Human
regulation of signal transduction GO:0009966 318 0.028
Human Rat
wound healing GO:0042060 122 0.028
multi multicellular organism process GO:0044706 138 0.028
response to peptide hormone GO:0043434 278 0.028
cellular response to endogenous stimulus GO:0071495 377 0.027
Rat
catabolic process GO:0009056 351 0.027
response to inorganic substance GO:0010035 377 0.027
response to vitamin GO:0033273 131 0.027
positive regulation of signaling GO:0023056 270 0.027
neuron projection development GO:0031175 273 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
Rat
mapk cascade GO:0000165 140 0.026
single organism biosynthetic process GO:0044711 342 0.026
regulation of molecular function GO:0065009 398 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.025
urogenital system development GO:0001655 78 0.025
circulatory system process GO:0003013 183 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
Human Rat
ribonucleotide metabolic process GO:0009259 231 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
response to extracellular stimulus GO:0009991 380 0.025
positive regulation of molecular function GO:0044093 230 0.025
cellular response to organic cyclic compound GO:0071407 202 0.024
rna metabolic process GO:0016070 406 0.024
Human
carbohydrate metabolic process GO:0005975 130 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
brain development GO:0007420 247 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
cell migration GO:0016477 197 0.024
homeostatic process GO:0042592 331 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
Human
establishment of protein localization GO:0045184 141 0.023
ion homeostasis GO:0050801 212 0.023
protein oligomerization GO:0051259 191 0.023
divalent inorganic cation transport GO:0072511 134 0.023
programmed cell death GO:0012501 392 0.023
Human
regulation of cellular amine metabolic process GO:0033238 8 0.023
intracellular signal transduction GO:0035556 314 0.023
negative regulation of cell communication GO:0010648 158 0.023
Human Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.023
regulation of protein modification process GO:0031399 194 0.022
protein phosphorylation GO:0006468 345 0.022
cellular component assembly GO:0022607 360 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
Human
embryonic skeletal system development GO:0048706 3 0.022
cell motility GO:0048870 202 0.022
organophosphate metabolic process GO:0019637 370 0.022
negative regulation of metabolic process GO:0009892 331 0.022
Human
regulation of cell differentiation GO:0045595 320 0.022
Human Rat
transcription dna templated GO:0006351 377 0.022
Human
protein complex subunit organization GO:0071822 302 0.022
response to growth factor GO:0070848 189 0.022
regulation of protein metabolic process GO:0051246 289 0.022
female sex differentiation GO:0046660 59 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
cellular response to alcohol GO:0097306 87 0.022
cellular amine metabolic process GO:0044106 38 0.021
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.021
Human Rat
cell growth GO:0016049 104 0.021
Human
response to estrogen GO:0043627 232 0.021
reproduction GO:0000003 245 0.021
positive regulation of cell proliferation GO:0008284 249 0.020
Human
cell projection organization GO:0030030 302 0.020
cell projection morphogenesis GO:0048858 123 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
Human
secretion GO:0046903 307 0.020
purine containing compound metabolic process GO:0072521 253 0.020
skeletal system development GO:0001501 41 0.020
regulation of neurogenesis GO:0050767 247 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
Human
action potential GO:0001508 54 0.019
chemical homeostasis GO:0048878 292 0.019
eye morphogenesis GO:0048592 4 0.019
striated muscle contraction GO:0006941 44 0.019
single organism catabolic process GO:0044712 283 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
positive regulation of gene expression GO:0010628 244 0.019
regulation of hormone levels GO:0010817 187 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
wnt signaling pathway calcium modulating pathway GO:0007223 1 0.019
purine nucleoside catabolic process GO:0006152 124 0.019
oxoacid metabolic process GO:0043436 290 0.019
cellular response to lipid GO:0071396 201 0.018
Rat
oxidation reduction process GO:0055114 304 0.018
regulation of transcription dna templated GO:0006355 374 0.018
Human
regulation of nucleotide metabolic process GO:0006140 117 0.018
female pregnancy GO:0007565 122 0.018
renal system development GO:0072001 67 0.018
regulation of cell projection organization GO:0031344 175 0.018
cellular macromolecule localization GO:0070727 122 0.018
ras protein signal transduction GO:0007265 29 0.017
response to carbohydrate GO:0009743 183 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
regulation of cell growth GO:0001558 85 0.017
Human
metal ion transport GO:0030001 289 0.017
response to dexamethasone GO:0071548 49 0.017
regulation of catabolic process GO:0009894 113 0.017
salivary gland development GO:0007431 3 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
multicellular organism reproduction GO:0032504 233 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
aging GO:0007568 241 0.017
positive regulation of cell development GO:0010720 176 0.017
response to ethanol GO:0045471 162 0.017
response to metal ion GO:0010038 253 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.017
response to insulin GO:0032868 133 0.016
axon development GO:0061564 96 0.016
response to ketone GO:1901654 182 0.016
Rat
regulation of protein localization GO:0032880 81 0.016
intracellular transport GO:0046907 185 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
vascular process in circulatory system GO:0003018 96 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
reproductive structure development GO:0048608 128 0.016
gliogenesis GO:0042063 93 0.016
developmental process involved in reproduction GO:0003006 159 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
negative regulation of cell death GO:0060548 229 0.016
regulation of transferase activity GO:0051338 123 0.016
regulation of protein transport GO:0051223 68 0.016
positive regulation of transport GO:0051050 245 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
cellular ketone metabolic process GO:0042180 51 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
response to acid chemical GO:0001101 222 0.015
Rat
organic substance catabolic process GO:1901575 316 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
ovulation cycle GO:0042698 67 0.015
nucleoside metabolic process GO:0009116 179 0.015
transmission of nerve impulse GO:0019226 42 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
growth GO:0040007 165 0.015
Human
cellular homeostasis GO:0019725 252 0.015
aromatic compound catabolic process GO:0019439 168 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
regulation of system process GO:0044057 208 0.015
heart morphogenesis GO:0003007 3 0.015
Human
negative regulation of protein metabolic process GO:0051248 114 0.015
regulation of response to stress GO:0080134 126 0.015
gastrulation GO:0007369 2 0.014
positive regulation of cell death GO:0010942 184 0.014
Human
negative regulation of multicellular organismal process GO:0051241 203 0.014
Human Rat
regulation of ion transport GO:0043269 245 0.014
regulation of kinase activity GO:0043549 117 0.014
central nervous system neuron axonogenesis GO:0021955 1 0.014
regulation of establishment of protein localization GO:0070201 69 0.014
synaptic transmission GO:0007268 235 0.014
cation transport GO:0006812 382 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
tissue morphogenesis GO:0048729 22 0.014
cellular protein localization GO:0034613 122 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
intracellular protein transport GO:0006886 79 0.014
mesoderm development GO:0007498 2 0.014
proteolysis GO:0006508 175 0.014
regulation of cell migration GO:0030334 128 0.014
cellular component morphogenesis GO:0032989 155 0.014
Human
development of primary female sexual characteristics GO:0046545 56 0.014
rhythmic process GO:0048511 156 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
positive regulation of secretion GO:0051047 140 0.014
response to peptide GO:1901652 292 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
monosaccharide metabolic process GO:0005996 61 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
establishment of tissue polarity GO:0007164 2 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
ovulation cycle process GO:0022602 50 0.013
regulation of protein kinase activity GO:0045859 105 0.013
protein complex biogenesis GO:0070271 263 0.013
cytoplasmic transport GO:0016482 115 0.013
cell type specific apoptotic process GO:0097285 134 0.013
regulation of behavior GO:0050795 61 0.013
response to mechanical stimulus GO:0009612 134 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
neuronal action potential GO:0019228 35 0.013
dna metabolic process GO:0006259 96 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of anatomical structure size GO:0090066 135 0.013
female gonad development GO:0008585 53 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
organ formation GO:0048645 3 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of nervous system development GO:0051960 264 0.013
locomotion GO:0040011 237 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
response to cytokine GO:0034097 215 0.013
cellular chemical homeostasis GO:0055082 247 0.013
cellular catabolic process GO:0044248 295 0.013
axon extension involved in axon guidance GO:0048846 6 0.012
defense response GO:0006952 194 0.012
axon midline choice point recognition GO:0016199 2 0.012
cell cycle GO:0007049 101 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
palate development GO:0060021 2 0.012
regulation of neuron differentiation GO:0045664 208 0.012
blood vessel morphogenesis GO:0048514 58 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
neurological system process GO:0050877 219 0.012
cellular response to external stimulus GO:0071496 118 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
Human
inflammatory response GO:0006954 150 0.012
regulation of body fluid levels GO:0050878 90 0.012
multicellular organismal signaling GO:0035637 44 0.012
developmental growth GO:0048589 100 0.012
establishment of planar polarity GO:0001736 1 0.012
gonad development GO:0008406 104 0.012
muscle system process GO:0003012 115 0.012
cellular response to ketone GO:1901655 51 0.012
Rat
blood vessel development GO:0001568 69 0.012
regulation of cellular component movement GO:0051270 150 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
regulation of secretion GO:0051046 224 0.012
limb morphogenesis GO:0035108 4 0.012
response to bacterium GO:0009617 200 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
cytoskeleton organization GO:0007010 111 0.012
epithelial cell proliferation GO:0050673 54 0.011
Human
sex differentiation GO:0007548 113 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
regulation of locomotion GO:0040012 148 0.011
cell part morphogenesis GO:0032990 123 0.011
glucose metabolic process GO:0006006 52 0.011
cell adhesion GO:0007155 110 0.011
positive regulation of nervous system development GO:0051962 178 0.011
heterocycle catabolic process GO:0046700 167 0.011
response to glucose GO:0009749 136 0.011
appendage morphogenesis GO:0035107 4 0.011
nucleotide catabolic process GO:0009166 139 0.011
ossification GO:0001503 70 0.011
Rat
circulatory system development GO:0072359 134 0.011
Human
carbohydrate derivative catabolic process GO:1901136 147 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
regulation of response to wounding GO:1903034 69 0.011
protein complex assembly GO:0006461 263 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
response to biotic stimulus GO:0009607 226 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
Human
regulation of muscle system process GO:0090257 79 0.011
negative regulation of molecular function GO:0044092 133 0.011
development of primary sexual characteristics GO:0045137 107 0.011
vasculature development GO:0001944 70 0.011
negative regulation of wnt signaling pathway GO:0030178 7 0.011
Human Rat
liver development GO:0001889 90 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
respiratory system development GO:0060541 45 0.011
nucleoside catabolic process GO:0009164 126 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
peptidyl amino acid modification GO:0018193 126 0.011
cation transmembrane transport GO:0098655 263 0.011
ion transmembrane transport GO:0034220 365 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
sequestering of calcium ion GO:0051208 8 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of neuron death GO:1901214 115 0.011
salivary gland morphogenesis GO:0007435 1 0.011
response to oxidative stress GO:0006979 186 0.010
response to lipopolysaccharide GO:0032496 191 0.010
cellular modified amino acid metabolic process GO:0006575 61 0.010
regulation of gtpase activity GO:0043087 57 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
Human
positive regulation of cellular component organization GO:0051130 200 0.010
response to vitamin a GO:0033189 36 0.010
response to estradiol GO:0032355 164 0.010
hexose metabolic process GO:0019318 58 0.010
axis specification GO:0009798 4 0.010
regulation of metal ion transport GO:0010959 118 0.010
heart development GO:0007507 72 0.010
Human
purine containing compound catabolic process GO:0072523 138 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
positive regulation of protein transport GO:0051222 41 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
neuron projection morphogenesis GO:0048812 122 0.010
ribonucleotide catabolic process GO:0009261 136 0.010

Sfrp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
urinary system disease DOID:18 0 0.012
nervous system disease DOID:863 0 0.012
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010