Rattus norvegicus

73 known processes

Grk6

G protein-coupled receptor kinase 6

(Aliases: Gprk6)

Grk6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component movement GO:0006928 248 0.150
single organism organelle organization GO:1902589 180 0.102
organic acid metabolic process GO:0006082 292 0.088
locomotion GO:0040011 237 0.086
regulation of cell proliferation GO:0042127 359 0.084
regulation of locomotion GO:0040012 148 0.081
metal ion transport GO:0030001 289 0.079
macromolecular complex subunit organization GO:0043933 339 0.078
oxoacid metabolic process GO:0043436 290 0.077
organelle organization GO:0006996 266 0.076
actin filament based process GO:0030029 86 0.075
regulation of nucleic acid templated transcription GO:1903506 380 0.071
negative regulation of metabolic process GO:0009892 331 0.071
regulation of rna biosynthetic process GO:2001141 381 0.069
carboxylic acid metabolic process GO:0019752 289 0.067
regulation of cellular localization GO:0060341 263 0.066
Rat
cellular response to endogenous stimulus GO:0071495 377 0.066
positive regulation of transport GO:0051050 245 0.065
Rat
nucleic acid templated transcription GO:0097659 379 0.064
reproductive process GO:0022414 372 0.064
Rat
positive regulation of biosynthetic process GO:0009891 319 0.063
protein localization GO:0008104 191 0.061
response to oxygen levels GO:0070482 265 0.061
regulation of signal transduction GO:0009966 318 0.059
regulation of transcription dna templated GO:0006355 374 0.058
regulation of organelle organization GO:0033043 80 0.055
organic substance catabolic process GO:1901575 316 0.054
intracellular transport GO:0046907 185 0.054
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
nucleobase containing small molecule metabolic process GO:0055086 316 0.051
immune system process GO:0002376 204 0.050
negative regulation of gene expression GO:0010629 199 0.050
cytoskeleton organization GO:0007010 111 0.049
behavior GO:0007610 205 0.049
cellular component assembly GO:0022607 360 0.048
positive regulation of response to stimulus GO:0048584 285 0.048
calcium ion homeostasis GO:0055074 162 0.048
cellular divalent inorganic cation homeostasis GO:0072503 162 0.047
vesicle mediated transport GO:0016192 181 0.047
Rat
cation homeostasis GO:0055080 195 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.046
regulation of cellular component movement GO:0051270 150 0.045
cation transport GO:0006812 382 0.045
protein autophosphorylation GO:0046777 66 0.044
Rat
regulation of protein metabolic process GO:0051246 289 0.044
calcium ion transport GO:0006816 131 0.044
positive regulation of nucleic acid templated transcription GO:1903508 197 0.044
regulation of cellular component organization GO:0051128 368 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
metal ion homeostasis GO:0055065 186 0.043
anatomical structure morphogenesis GO:0009653 298 0.043
homeostatic process GO:0042592 331 0.042
chemical homeostasis GO:0048878 292 0.042
positive regulation of cellular component organization GO:0051130 200 0.042
cellular metal ion homeostasis GO:0006875 172 0.042
aging GO:0007568 241 0.042
Rat
response to extracellular stimulus GO:0009991 380 0.042
divalent metal ion transport GO:0070838 132 0.042
cellular response to oxygen containing compound GO:1901701 386 0.041
response to biotic stimulus GO:0009607 226 0.040
multicellular organism reproduction GO:0032504 233 0.040
Rat
ion transmembrane transport GO:0034220 365 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.038
intracellular signal transduction GO:0035556 314 0.038
response to external biotic stimulus GO:0043207 221 0.038
rna metabolic process GO:0016070 406 0.038
transmembrane transport GO:0055085 412 0.038
positive regulation of cellular component movement GO:0051272 102 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.037
positive regulation of transcription dna templated GO:0045893 197 0.037
transcription dna templated GO:0006351 377 0.037
regulation of molecular function GO:0065009 398 0.037
regulation of rna metabolic process GO:0051252 391 0.036
catabolic process GO:0009056 351 0.036
regulation of cell differentiation GO:0045595 320 0.035
rna biosynthetic process GO:0032774 380 0.035
cellular response to growth factor stimulus GO:0071363 162 0.035
inorganic cation transmembrane transport GO:0098662 202 0.035
macromolecule localization GO:0033036 252 0.034
protein complex biogenesis GO:0070271 263 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
programmed cell death GO:0012501 392 0.033
cellular calcium ion homeostasis GO:0006874 160 0.033
multi organism reproductive process GO:0044703 262 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.032
negative regulation of protein metabolic process GO:0051248 114 0.032
nucleoside metabolic process GO:0009116 179 0.031
positive regulation of signal transduction GO:0009967 175 0.031
cytosolic calcium ion homeostasis GO:0051480 140 0.031
single organism behavior GO:0044708 130 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
secretion GO:0046903 307 0.029
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.029
proteolysis GO:0006508 175 0.029
response to transforming growth factor beta GO:0071559 46 0.029
regulation of vesicle mediated transport GO:0060627 81 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
protein complex assembly GO:0006461 263 0.029
divalent inorganic cation transport GO:0072511 134 0.029
cellular component biogenesis GO:0044085 368 0.029
ion homeostasis GO:0050801 212 0.028
cellular response to stress GO:0033554 269 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
response to growth factor GO:0070848 189 0.028
positive regulation of molecular function GO:0044093 230 0.027
actin filament bundle organization GO:0061572 19 0.027
response to other organism GO:0051707 220 0.026
g protein coupled receptor signaling pathway GO:0007186 242 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
cell motility GO:0048870 202 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
single organism intracellular transport GO:1902582 166 0.026
amine metabolic process GO:0009308 38 0.026
immune response GO:0006955 104 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
regulation of phosphate metabolic process GO:0019220 349 0.025
protein complex subunit organization GO:0071822 302 0.025
nitrogen compound transport GO:0071705 229 0.025
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
regulation of phosphorylation GO:0042325 248 0.024
cell morphogenesis GO:0000902 142 0.024
response to hydrogen peroxide GO:0042542 89 0.024
Rat
response to decreased oxygen levels GO:0036293 237 0.024
cellular catabolic process GO:0044248 295 0.024
response to cytokine GO:0034097 215 0.024
gamete generation GO:0007276 124 0.024
defense response GO:0006952 194 0.024
neuron projection development GO:0031175 273 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
Rat
response to lipopolysaccharide GO:0032496 191 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
cellular homeostasis GO:0019725 252 0.023
regulation of homeostatic process GO:0032844 101 0.023
cellular ketone metabolic process GO:0042180 51 0.023
protein oligomerization GO:0051259 191 0.023
localization of cell GO:0051674 202 0.023
cellular ion homeostasis GO:0006873 184 0.023
cellular chemical homeostasis GO:0055082 247 0.023
sequestering of calcium ion GO:0051208 8 0.023
single organism reproductive process GO:0044702 297 0.023
Rat
negative regulation of signaling GO:0023057 157 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
alternative mrna splicing via spliceosome GO:0000380 4 0.022
regulation of cell cycle GO:0051726 73 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
muscle tissue morphogenesis GO:0060415 1 0.021
glycosyl compound metabolic process GO:1901657 182 0.021
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.021
carboxylic acid transport GO:0046942 115 0.021
synaptic growth at neuromuscular junction GO:0051124 1 0.021
macromolecule catabolic process GO:0009057 58 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
organophosphate metabolic process GO:0019637 370 0.021
negative regulation of cellular component organization GO:0051129 83 0.021
negative regulation of signal transduction GO:0009968 83 0.021
regulation of apoptotic process GO:0042981 335 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
spindle organization GO:0007051 2 0.021
cellular amine metabolic process GO:0044106 38 0.020
single organism biosynthetic process GO:0044711 342 0.020
negative regulation of molecular function GO:0044092 133 0.020
regulation of cell motility GO:2000145 131 0.020
reproduction GO:0000003 245 0.020
Rat
blood circulation GO:0008015 183 0.020
regulation of secretion by cell GO:1903530 208 0.020
Rat
regulation of catalytic activity GO:0050790 304 0.020
adult locomotory behavior GO:0008344 4 0.020
positive regulation of protein modification process GO:0031401 142 0.020
ribonucleoside metabolic process GO:0009119 174 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
purine containing compound metabolic process GO:0072521 253 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
ras protein signal transduction GO:0007265 29 0.019
regulation of neuron projection development GO:0010975 161 0.019
positive regulation of gene expression GO:0010628 244 0.019
protein transport GO:0015031 132 0.019
positive regulation of developmental process GO:0051094 283 0.019
regulation of neuron apoptotic process GO:0043523 83 0.019
neuron differentiation GO:0030182 368 0.019
response to radiation GO:0009314 137 0.018
Rat
negative regulation of transport GO:0051051 136 0.018
response to peptide hormone GO:0043434 278 0.018
regulation of neurogenesis GO:0050767 247 0.018
development of primary sexual characteristics GO:0045137 107 0.018
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
cellular cation homeostasis GO:0030003 180 0.018
actin cytoskeleton organization GO:0030036 73 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
regulation of metal ion transport GO:0010959 118 0.018
protein processing GO:0016485 68 0.018
cellular macromolecule catabolic process GO:0044265 29 0.018
regulation of programmed cell death GO:0043067 341 0.018
negative regulation of homeostatic process GO:0032845 47 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
heterocycle catabolic process GO:0046700 167 0.017
purine containing compound catabolic process GO:0072523 138 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
Rat
lipid biosynthetic process GO:0008610 128 0.017
response to inorganic substance GO:0010035 377 0.017
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of nervous system development GO:0051960 264 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
negative regulation of programmed cell death GO:0043069 183 0.016
axis specification GO:0009798 4 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
actin filament organization GO:0007015 42 0.016
endocytosis GO:0006897 84 0.016
Rat
cellular response to peptide GO:1901653 133 0.016
protein phosphorylation GO:0006468 345 0.016
macromolecular complex assembly GO:0065003 273 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
response to axon injury GO:0048678 59 0.016
regulation of kinase activity GO:0043549 117 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
olfactory behavior GO:0042048 2 0.016
taxis GO:0042330 67 0.015
multicellular organismal homeostasis GO:0048871 49 0.015
cation transmembrane transport GO:0098655 263 0.015
meiotic cell cycle process GO:1903046 3 0.015
cell substrate adhesion GO:0031589 29 0.015
neuron development GO:0048666 286 0.015
cell migration GO:0016477 197 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
establishment of protein localization GO:0045184 141 0.015
cytoplasmic transport GO:0016482 115 0.015
cell projection organization GO:0030030 302 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
negative regulation of developmental process GO:0051093 125 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
negative regulation of innate immune response GO:0045824 4 0.015
apoptotic process GO:0006915 381 0.015
positive regulation of nervous system development GO:0051962 178 0.015
organic cyclic compound catabolic process GO:1901361 175 0.014
negative regulation of rna splicing GO:0033119 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
sexual reproduction GO:0019953 148 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
cell cycle GO:0007049 101 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of ion transport GO:0043269 245 0.014
regulation of gene expression epigenetic GO:0040029 10 0.014
atp metabolic process GO:0046034 72 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
regulation of cell projection organization GO:0031344 175 0.014
b cell differentiation GO:0030183 2 0.014
response to peptide GO:1901652 292 0.014
positive regulation of calcium ion transport GO:0051928 36 0.014
chromatin organization GO:0006325 34 0.014
response to nutrient levels GO:0031667 370 0.014
tissue remodeling GO:0048771 40 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
cell cell signaling GO:0007267 335 0.014
cellular macromolecule localization GO:0070727 122 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
calcium ion transport into cytosol GO:0060402 38 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
muscle structure development GO:0061061 87 0.014
positive regulation of cell death GO:0010942 184 0.014
organic acid transport GO:0015849 116 0.014
signal release GO:0023061 145 0.013
response to bacterium GO:0009617 200 0.013
positive regulation of ion transport GO:0043270 94 0.013
aromatic compound catabolic process GO:0019439 168 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
organic hydroxy compound transport GO:0015850 77 0.013
Rat
positive regulation of locomotion GO:0040017 102 0.013
response to acid chemical GO:0001101 222 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
negative regulation of neuron apoptotic process GO:0043524 45 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.013
positive regulation of cell motility GO:2000147 97 0.013
regulation of protein modification process GO:0031399 194 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
positive regulation of immune system process GO:0002684 90 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of ion homeostasis GO:2000021 63 0.013
positive regulation of apoptotic process GO:0043065 154 0.012
actin filament polymerization GO:0030041 11 0.012
sex differentiation GO:0007548 113 0.012
Rat
sequestering of metal ion GO:0051238 9 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
striated muscle cell development GO:0055002 26 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
response to oxidative stress GO:0006979 186 0.012
Rat
reactive nitrogen species metabolic process GO:2001057 1 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
regulation of cell development GO:0060284 263 0.012
neuron apoptotic process GO:0051402 88 0.012
reproductive system development GO:0061458 128 0.012
Rat
maintenance of location GO:0051235 17 0.012
regulation of cell growth GO:0001558 85 0.012
regulation of protein localization GO:0032880 81 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
chemotaxis GO:0006935 66 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
ribonucleoside monophosphate catabolic process GO:0009158 55 0.012
response to toxic substance GO:0009636 133 0.012
positive regulation of lymphocyte proliferation GO:0050671 20 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
Rat
lipid metabolic process GO:0006629 283 0.012
secretion by cell GO:0032940 248 0.012
Rat
regulation of transmembrane transport GO:0034762 122 0.012
regulation of calcium ion transport GO:0051924 77 0.012
response to molecule of bacterial origin GO:0002237 194 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
axonogenesis GO:0007409 71 0.011
muscle system process GO:0003012 115 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
chemosensory behavior GO:0007635 2 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
positive regulation of signaling GO:0023056 270 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
organic anion transport GO:0015711 132 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
protein polymerization GO:0051258 22 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
amino acid transport GO:0006865 70 0.011
response to estrogen GO:0043627 232 0.011
reproductive structure development GO:0048608 128 0.011
Rat
follicle stimulating hormone signaling pathway GO:0042699 5 0.011
Rat
neuron death GO:0070997 127 0.011
regulation of growth GO:0040008 105 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
oxidation reduction process GO:0055114 304 0.011
regulation of protein kinase activity GO:0045859 105 0.011
cell adhesion GO:0007155 110 0.011
regulation of hormone levels GO:0010817 187 0.011
cellular protein localization GO:0034613 122 0.011
positive regulation of cell development GO:0010720 176 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
neuron projection guidance GO:0097485 24 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.010
response to reactive oxygen species GO:0000302 120 0.010
Rat
embryonic pattern specification GO:0009880 1 0.010
positive regulation of organelle organization GO:0010638 48 0.010
regulation of secretion GO:0051046 224 0.010
Rat
sulfur compound metabolic process GO:0006790 70 0.010
cellular component morphogenesis GO:0032989 155 0.010
organelle assembly GO:0070925 22 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
protein localization to organelle GO:0033365 57 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
regeneration GO:0031099 163 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
positive regulation of cell migration GO:0030335 96 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010

Grk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
neuropathy DOID:870 0 0.013