Rattus norvegicus

31 known processes

St8sia1

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

(Aliases: Siat8,Siat8a)

St8sia1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to insulin GO:0032868 133 0.314
positive regulation of multicellular organismal process GO:0051240 387 0.225
behavior GO:0007610 205 0.192
negative regulation of cellular metabolic process GO:0031324 281 0.184
response to peptide GO:1901652 292 0.183
organelle organization GO:0006996 266 0.172
regulation of rna biosynthetic process GO:2001141 381 0.169
regulation of programmed cell death GO:0043067 341 0.161
regulation of nucleic acid templated transcription GO:1903506 380 0.156
lipid metabolic process GO:0006629 283 0.145
carboxylic acid metabolic process GO:0019752 289 0.144
oxoacid metabolic process GO:0043436 290 0.137
programmed cell death GO:0012501 392 0.137
lipid biosynthetic process GO:0008610 128 0.124
cell cell signaling GO:0007267 335 0.120
negative regulation of metabolic process GO:0009892 331 0.120
neurological system process GO:0050877 219 0.119
chemical homeostasis GO:0048878 292 0.114
regulation of multicellular organismal development GO:2000026 376 0.113
negative regulation of cell death GO:0060548 229 0.110
cardiovascular system development GO:0072358 134 0.106
response to inorganic substance GO:0010035 377 0.105
rna metabolic process GO:0016070 406 0.100
single organism biosynthetic process GO:0044711 342 0.098
response to estrogen GO:0043627 232 0.092
regulation of cell development GO:0060284 263 0.091
cellular response to oxygen containing compound GO:1901701 386 0.090
regulation of cellular component organization GO:0051128 368 0.086
multicellular organismal reproductive process GO:0048609 233 0.084
neuron development GO:0048666 286 0.082
cellular response to insulin stimulus GO:0032869 81 0.081
gland development GO:0048732 155 0.080
anatomical structure morphogenesis GO:0009653 298 0.079
response to ketone GO:1901654 182 0.076
neuron differentiation GO:0030182 368 0.073
cellular response to organonitrogen compound GO:0071417 197 0.071
cellular response to peptide GO:1901653 133 0.070
organ morphogenesis GO:0009887 75 0.070
cellular ketone metabolic process GO:0042180 51 0.070
response to peptide hormone GO:0043434 278 0.069
positive regulation of biosynthetic process GO:0009891 319 0.067
rna biosynthetic process GO:0032774 380 0.065
positive regulation of developmental process GO:0051094 283 0.065
response to hexose GO:0009746 144 0.063
cellular component biogenesis GO:0044085 368 0.063
apoptotic process GO:0006915 381 0.062
regulation of secretion by cell GO:1903530 208 0.062
reproductive process GO:0022414 372 0.061
negative regulation of cell communication GO:0010648 158 0.061
monocarboxylic acid metabolic process GO:0032787 152 0.061
liver development GO:0001889 90 0.061
regulation of signal transduction GO:0009966 318 0.060
cellular component morphogenesis GO:0032989 155 0.059
negative regulation of gene expression GO:0010629 199 0.058
cellular response to endogenous stimulus GO:0071495 377 0.057
hepaticobiliary system development GO:0061008 90 0.057
neuron projection morphogenesis GO:0048812 122 0.056
developmental process involved in reproduction GO:0003006 159 0.056
response to extracellular stimulus GO:0009991 380 0.055
amide transport GO:0042886 105 0.054
regulation of neurogenesis GO:0050767 247 0.052
cellular response to peptide hormone stimulus GO:0071375 120 0.051
positive regulation of transport GO:0051050 245 0.050
macromolecule localization GO:0033036 252 0.048
secretion GO:0046903 307 0.048
secretion by cell GO:0032940 248 0.048
positive regulation of gene expression GO:0010628 244 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
regulation of cell differentiation GO:0045595 320 0.047
cellular response to hormone stimulus GO:0032870 247 0.046
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.046
regulation of cellular localization GO:0060341 263 0.045
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.045
transcription dna templated GO:0006351 377 0.045
tissue development GO:0009888 252 0.044
nucleic acid templated transcription GO:0097659 379 0.044
regulation of protein metabolic process GO:0051246 289 0.043
cellular homeostasis GO:0019725 252 0.043
cellular lipid metabolic process GO:0044255 208 0.043
protein phosphorylation GO:0006468 345 0.042
negative regulation of programmed cell death GO:0043069 183 0.042
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
glycerolipid metabolic process GO:0046486 67 0.041
oxidation reduction process GO:0055114 304 0.040
regulation of body fluid levels GO:0050878 90 0.040
positive regulation of signaling GO:0023056 270 0.040
negative regulation of apoptotic process GO:0043066 181 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
regulation of transcription dna templated GO:0006355 374 0.038
positive regulation of nervous system development GO:0051962 178 0.038
positive regulation of rna biosynthetic process GO:1902680 197 0.037
reproductive system development GO:0061458 128 0.037
regulation of nervous system development GO:0051960 264 0.036
protein complex assembly GO:0006461 263 0.036
regulation of membrane potential GO:0042391 110 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
catabolic process GO:0009056 351 0.035
multicellular organism reproduction GO:0032504 233 0.033
response to radiation GO:0009314 137 0.033
organic hydroxy compound metabolic process GO:1901615 115 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
negative regulation of signaling GO:0023057 157 0.032
protein complex subunit organization GO:0071822 302 0.032
regulation of neuron differentiation GO:0045664 208 0.032
macromolecular complex assembly GO:0065003 273 0.032
cell morphogenesis GO:0000902 142 0.031
aging GO:0007568 241 0.031
negative regulation of response to stimulus GO:0048585 155 0.030
positive regulation of cell development GO:0010720 176 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
regulation of locomotion GO:0040012 148 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
regulation of hormone levels GO:0010817 187 0.029
circadian rhythm GO:0007623 88 0.029
neuron death GO:0070997 127 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
single organism organelle organization GO:1902589 180 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
fatty acid metabolic process GO:0006631 99 0.028
head development GO:0060322 247 0.028
growth GO:0040007 165 0.028
neuron projection development GO:0031175 273 0.028
organophosphate metabolic process GO:0019637 370 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
negative regulation of signal transduction GO:0009968 83 0.027
regulation of lipid metabolic process GO:0019216 68 0.027
regulation of neuron projection development GO:0010975 161 0.027
cellular chemical homeostasis GO:0055082 247 0.027
protein oligomerization GO:0051259 191 0.027
anion transport GO:0006820 178 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.027
cellular component assembly GO:0022607 360 0.026
establishment of organelle localization GO:0051656 37 0.026
amine metabolic process GO:0009308 38 0.026
response to glucocorticoid GO:0051384 223 0.026
blood circulation GO:0008015 183 0.026
carbohydrate homeostasis GO:0033500 75 0.025
cellular catabolic process GO:0044248 295 0.025
prepulse inhibition GO:0060134 1 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
intracellular signal transduction GO:0035556 314 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.025
cell activation GO:0001775 97 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
response to other organism GO:0051707 220 0.025
single organism reproductive process GO:0044702 297 0.025
myeloid leukocyte differentiation GO:0002573 20 0.025
response to decreased oxygen levels GO:0036293 237 0.025
regulation of response to external stimulus GO:0032101 106 0.024
neuron apoptotic process GO:0051402 88 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
vesicle mediated transport GO:0016192 181 0.024
response to corticosteroid GO:0031960 235 0.024
hormone transport GO:0009914 121 0.024
response to ammonium ion GO:0060359 71 0.024
cell type specific apoptotic process GO:0097285 134 0.024
regulation of neuron death GO:1901214 115 0.023
neurotransmitter transport GO:0006836 42 0.023
heart morphogenesis GO:0003007 3 0.023
carbohydrate derivative biosynthetic process GO:1901137 124 0.023
response to nutrient levels GO:0031667 370 0.023
positive regulation of cell death GO:0010942 184 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
neuronal action potential GO:0019228 35 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
response to carbohydrate GO:0009743 183 0.023
cellular response to lipid GO:0071396 201 0.023
cation transmembrane transport GO:0098655 263 0.023
reproductive structure development GO:0048608 128 0.023
response to ethanol GO:0045471 162 0.023
transmission of nerve impulse GO:0019226 42 0.022
regulation of apoptotic process GO:0042981 335 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
steroid metabolic process GO:0008202 73 0.022
protein complex biogenesis GO:0070271 263 0.022
cell projection organization GO:0030030 302 0.022
organic acid metabolic process GO:0006082 292 0.022
synaptic transmission GO:0007268 235 0.021
action potential GO:0001508 54 0.021
regulation of cell proliferation GO:0042127 359 0.021
Mouse
response to antibiotic GO:0046677 39 0.021
cellular ion homeostasis GO:0006873 184 0.020
negative regulation of protein maturation GO:1903318 47 0.020
response to toxic substance GO:0009636 133 0.020
lipid catabolic process GO:0016042 46 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
developmental growth GO:0048589 100 0.020
circulatory system development GO:0072359 134 0.020
cellular amine metabolic process GO:0044106 38 0.020
positive regulation of secretion by cell GO:1903532 128 0.020
kidney development GO:0001822 67 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
reproduction GO:0000003 245 0.020
response to growth factor GO:0070848 189 0.020
muscle organ development GO:0007517 50 0.020
response to nutrient GO:0007584 248 0.019
cellular response to alcohol GO:0097306 87 0.019
negative regulation of growth GO:0045926 37 0.019
regulation of cell projection organization GO:0031344 175 0.019
response to wounding GO:0009611 254 0.019
response to glucose GO:0009749 136 0.019
regulation of vesicle mediated transport GO:0060627 81 0.019
response to estradiol GO:0032355 164 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
response to hypoxia GO:0001666 231 0.019
mammary gland development GO:0030879 38 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
proteolysis GO:0006508 175 0.018
homeostatic process GO:0042592 331 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
regulation of synaptic transmission GO:0050804 141 0.018
phototransduction visible light GO:0007603 2 0.018
negative regulation of neuron death GO:1901215 69 0.018
regulation of amine transport GO:0051952 54 0.018
negative regulation of cell development GO:0010721 82 0.018
brain development GO:0007420 247 0.018
negative regulation of protein modification process GO:0031400 52 0.018
axonogenesis GO:0007409 71 0.017
multi organism reproductive process GO:0044703 262 0.017
lipid storage GO:0019915 1 0.017
regulation of defense response GO:0031347 68 0.017
anterior posterior pattern specification GO:0009952 1 0.017
regulation of protein maturation GO:1903317 50 0.017
regulation of catabolic process GO:0009894 113 0.017
negative regulation of protein phosphorylation GO:0001933 44 0.017
embryo development GO:0009790 49 0.017
axon ensheathment GO:0008366 40 0.017
central nervous system development GO:0007417 311 0.017
urogenital system development GO:0001655 78 0.017
negative regulation of transport GO:0051051 136 0.017
regulation of molecular function GO:0065009 398 0.017
response to interleukin 15 GO:0070672 4 0.017
potassium ion transport GO:0006813 97 0.016
glucose homeostasis GO:0042593 75 0.016
regulation of insulin secretion GO:0050796 65 0.016
steroid biosynthetic process GO:0006694 48 0.016
single organism behavior GO:0044708 130 0.016
endocytosis GO:0006897 84 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
insulin receptor signaling pathway GO:0008286 24 0.016
nitrogen compound transport GO:0071705 229 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
muscle structure development GO:0061061 87 0.016
positive regulation of lipid metabolic process GO:0045834 33 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
hormone secretion GO:0046879 115 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
regulation of hormone secretion GO:0046883 106 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
mapk cascade GO:0000165 140 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
relaxation of vascular smooth muscle GO:0060087 1 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
epithelial cell differentiation GO:0030855 71 0.015
negative regulation of epithelial cell proliferation GO:0050680 16 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
sensory organ development GO:0007423 74 0.015
positive regulation of lipid biosynthetic process GO:0046889 25 0.015
cardiac chamber development GO:0003205 1 0.015
rhythmic process GO:0048511 156 0.015
regulation of neuron apoptotic process GO:0043523 83 0.015
regulation of catalytic activity GO:0050790 304 0.014
regulation of phosphorylation GO:0042325 248 0.014
gonad development GO:0008406 104 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
protein maturation GO:0051604 68 0.014
tube development GO:0035295 89 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
gamete generation GO:0007276 124 0.014
single organism membrane organization GO:0044802 74 0.014
neurotrophin production GO:0032898 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
regulation of protein modification process GO:0031399 194 0.014
cognition GO:0050890 92 0.014
cell cycle GO:0007049 101 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
ion homeostasis GO:0050801 212 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
leukocyte differentiation GO:0002521 30 0.014
epithelium development GO:0060429 96 0.014
dendrite development GO:0016358 72 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
response to cytokine GO:0034097 215 0.014
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.014
purine nucleoside metabolic process GO:0042278 169 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
carbohydrate metabolic process GO:0005975 130 0.013
sexual reproduction GO:0019953 148 0.013
regulation of rna metabolic process GO:0051252 391 0.013
pancreatic a cell differentiation GO:0003310 1 0.013
regulation of secretion GO:0051046 224 0.013
organic substance catabolic process GO:1901575 316 0.013
ensheathment of neurons GO:0007272 40 0.013
acetylcholine secretion GO:0061526 4 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
positive regulation of catabolic process GO:0009896 78 0.013
blood vessel development GO:0001568 69 0.013
purine nucleotide transport GO:0015865 3 0.013
regulation of peptide secretion GO:0002791 82 0.013
cellular protein localization GO:0034613 122 0.013
response to purine containing compound GO:0014074 126 0.012
nucleotide metabolic process GO:0009117 279 0.012
dna metabolic process GO:0006259 96 0.012
behavioral response to ethanol GO:0048149 1 0.012
detection of stimulus GO:0051606 24 0.012
male gamete generation GO:0048232 99 0.012
chemosensory behavior GO:0007635 2 0.012
myelination GO:0042552 39 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
cell adhesion GO:0007155 110 0.012
response to hydrogen peroxide GO:0042542 89 0.012
peptide hormone secretion GO:0030072 84 0.012
response to external biotic stimulus GO:0043207 221 0.012
negative regulation of organ growth GO:0046621 3 0.012
eye development GO:0001654 50 0.012
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
immune system development GO:0002520 41 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
regeneration GO:0031099 163 0.012
negative regulation of collagen biosynthetic process GO:0032966 4 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
regulation of kinase activity GO:0043549 117 0.011
negative regulation of circadian sleep wake cycle non rem sleep GO:0042323 2 0.011
regulation of growth GO:0040008 105 0.011
response to biotic stimulus GO:0009607 226 0.011
female pregnancy GO:0007565 122 0.011
monosaccharide transport GO:0015749 31 0.011
response to acid chemical GO:0001101 222 0.011
monosaccharide metabolic process GO:0005996 61 0.011
cellular component movement GO:0006928 248 0.011
female gonad development GO:0008585 53 0.011
epithelial cell proliferation GO:0050673 54 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
actin filament based process GO:0030029 86 0.011
peptide transport GO:0015833 97 0.011
positive regulation of immune system process GO:0002684 90 0.011
memory GO:0007613 54 0.011
acetylcholine secretion neurotransmission GO:0014055 4 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
carboxylic acid transport GO:0046942 115 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
adenine nucleotide transport GO:0051503 2 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
muscle contraction GO:0006936 88 0.011
transmembrane transport GO:0055085 412 0.011
response to testosterone GO:0033574 55 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
cellular response to ketone GO:1901655 51 0.011
protein processing GO:0016485 68 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
positive regulation of protein modification process GO:0031401 142 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
renal system development GO:0072001 67 0.010
response to oxygen levels GO:0070482 265 0.010
cellular response to stress GO:0033554 269 0.010
Mouse
lipid modification GO:0030258 52 0.010
regulation of lipid biosynthetic process GO:0046890 38 0.010
regulation of muscle organ development GO:0048634 26 0.010
cellular response to glucose stimulus GO:0071333 65 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
sensory perception of bitter taste GO:0050913 4 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
development of primary sexual characteristics GO:0045137 107 0.010
membrane organization GO:0061024 94 0.010
single organism intracellular transport GO:1902582 166 0.010
axon development GO:0061564 96 0.010
nucleoside transport GO:0015858 8 0.010
cellular response to monosaccharide stimulus GO:0071326 67 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010

St8sia1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.044
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
retinal disease DOID:5679 0 0.036
eye and adnexa disease DOID:1492 0 0.036
eye disease DOID:5614 0 0.036
night blindness DOID:8499 0 0.025
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.011