Rattus norvegicus

0 known processes

Ttc7

tetratricopeptide repeat domain 7

Ttc7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell death GO:0010942 184 0.151
regulation of apoptotic process GO:0042981 335 0.135
carboxylic acid metabolic process GO:0019752 289 0.120
regulation of cell proliferation GO:0042127 359 0.108
homeostatic process GO:0042592 331 0.088
cellular amino acid metabolic process GO:0006520 107 0.080
response to inorganic substance GO:0010035 377 0.076
regulation of cellular ketone metabolic process GO:0010565 27 0.072
cellular response to oxygen containing compound GO:1901701 386 0.072
response to wounding GO:0009611 254 0.067
cellular ketone metabolic process GO:0042180 51 0.066
organic acid metabolic process GO:0006082 292 0.064
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.059
regulation of molecular function GO:0065009 398 0.059
regulation of phosphate metabolic process GO:0019220 349 0.059
regulation of cellular component organization GO:0051128 368 0.056
positive regulation of programmed cell death GO:0043068 157 0.056
regulation of rna biosynthetic process GO:2001141 381 0.055
regulation of programmed cell death GO:0043067 341 0.054
protein phosphorylation GO:0006468 345 0.053
positive regulation of response to stimulus GO:0048584 285 0.053
rna metabolic process GO:0016070 406 0.052
cell projection organization GO:0030030 302 0.051
apoptotic process GO:0006915 381 0.050
nucleic acid templated transcription GO:0097659 379 0.050
programmed cell death GO:0012501 392 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
positive regulation of cell communication GO:0010647 271 0.048
positive regulation of biosynthetic process GO:0009891 319 0.048
single organism biosynthetic process GO:0044711 342 0.047
neuron development GO:0048666 286 0.047
cellular component movement GO:0006928 248 0.046
oxoacid metabolic process GO:0043436 290 0.046
rna biosynthetic process GO:0032774 380 0.046
carbohydrate derivative metabolic process GO:1901135 346 0.045
regulation of protein kinase activity GO:0045859 105 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.044
leukotriene biosynthetic process GO:0019370 3 0.044
regulation of system process GO:0044057 208 0.043
response to extracellular stimulus GO:0009991 380 0.043
multi organism reproductive process GO:0044703 262 0.042
reproductive process GO:0022414 372 0.042
response to carbohydrate GO:0009743 183 0.042
transcription dna templated GO:0006351 377 0.042
blood circulation GO:0008015 183 0.041
regulation of locomotion GO:0040012 148 0.041
negative regulation of multicellular organismal process GO:0051241 203 0.040
regulation of protein metabolic process GO:0051246 289 0.040
cellular component assembly GO:0022607 360 0.040
positive regulation of transport GO:0051050 245 0.040
single organism catabolic process GO:0044712 283 0.040
organophosphate metabolic process GO:0019637 370 0.039
regulation of cellular amino acid metabolic process GO:0006521 2 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
positive regulation of cellular protein metabolic process GO:0032270 167 0.037
positive regulation of signal transduction GO:0009967 175 0.037
endocytosis GO:0006897 84 0.037
positive regulation of cell proliferation GO:0008284 249 0.037
regulation of smooth muscle cell proliferation GO:0048660 75 0.037
regulation of cell motility GO:2000145 131 0.037
central nervous system development GO:0007417 311 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
response to metal ion GO:0010038 253 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
response to oxygen levels GO:0070482 265 0.035
intracellular signal transduction GO:0035556 314 0.035
secretion GO:0046903 307 0.035
cellular amine metabolic process GO:0044106 38 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
regulation of catalytic activity GO:0050790 304 0.034
cellular lipid metabolic process GO:0044255 208 0.034
regulation of vesicle mediated transport GO:0060627 81 0.034
regulation of signal transduction GO:0009966 318 0.034
localization of cell GO:0051674 202 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
cellular response to external stimulus GO:0071496 118 0.034
cell adhesion GO:0007155 110 0.034
cellular component morphogenesis GO:0032989 155 0.033
organelle organization GO:0006996 266 0.033
amine metabolic process GO:0009308 38 0.033
regulation of cell differentiation GO:0045595 320 0.033
cell migration GO:0016477 197 0.032
response to nutrient levels GO:0031667 370 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
organic substance catabolic process GO:1901575 316 0.032
response to bacterium GO:0009617 200 0.031
positive regulation of map kinase activity GO:0043406 46 0.031
response to temperature stimulus GO:0009266 94 0.031
vesicle mediated transport GO:0016192 181 0.030
regulation of transferase activity GO:0051338 123 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.030
regulation of protein phosphorylation GO:0001932 183 0.030
glycosyl compound metabolic process GO:1901657 182 0.029
regulation of cellular localization GO:0060341 263 0.029
regulation of rna metabolic process GO:0051252 391 0.029
catabolic process GO:0009056 351 0.029
regulation of secretion GO:0051046 224 0.029
small molecule biosynthetic process GO:0044283 124 0.028
cell morphogenesis GO:0000902 142 0.028
positive regulation of signaling GO:0023056 270 0.028
cellular catabolic process GO:0044248 295 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
single organismal cell cell adhesion GO:0016337 42 0.028
nucleoside metabolic process GO:0009116 179 0.028
regulation of kinase activity GO:0043549 117 0.028
positive regulation of cellular component organization GO:0051130 200 0.028
organonitrogen compound catabolic process GO:1901565 179 0.027
positive regulation of gene expression GO:0010628 244 0.027
regulation of cell development GO:0060284 263 0.027
locomotion GO:0040011 237 0.027
response to decreased oxygen levels GO:0036293 237 0.027
regulation of neurogenesis GO:0050767 247 0.027
cellular response to endogenous stimulus GO:0071495 377 0.027
response to ketone GO:1901654 182 0.027
negative regulation of cell communication GO:0010648 158 0.027
chemical homeostasis GO:0048878 292 0.027
carboxylic acid biosynthetic process GO:0046394 83 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
neuron death GO:0070997 127 0.027
regulation of protein modification process GO:0031399 194 0.026
multi multicellular organism process GO:0044706 138 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
response to biotic stimulus GO:0009607 226 0.026
purine containing compound catabolic process GO:0072523 138 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
gland development GO:0048732 155 0.026
muscle cell proliferation GO:0033002 84 0.026
female pregnancy GO:0007565 122 0.026
defense response GO:0006952 194 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
regulation of neuron death GO:1901214 115 0.026
protein complex subunit organization GO:0071822 302 0.025
response to hypoxia GO:0001666 231 0.025
response to vitamin GO:0033273 131 0.025
cellular response to stress GO:0033554 269 0.025
circulatory system process GO:0003013 183 0.025
ion transmembrane transport GO:0034220 365 0.025
response to other organism GO:0051707 220 0.025
cellular modified amino acid metabolic process GO:0006575 61 0.025
cell cell signaling GO:0007267 335 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
biological adhesion GO:0022610 110 0.025
heterocycle catabolic process GO:0046700 167 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
response to reactive oxygen species GO:0000302 120 0.025
immune response GO:0006955 104 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
cardiac conduction GO:0061337 2 0.024
intracellular transport GO:0046907 185 0.024
neuron differentiation GO:0030182 368 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.024
regulation of stem cell differentiation GO:2000736 2 0.024
adult locomotory behavior GO:0008344 4 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
negative regulation of response to stimulus GO:0048585 155 0.023
regulation of secretion by cell GO:1903530 208 0.023
transmembrane transport GO:0055085 412 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
organophosphate catabolic process GO:0046434 148 0.023
dephosphorylation GO:0016311 98 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
regulation of cellular component movement GO:0051270 150 0.023
cell motility GO:0048870 202 0.023
metal ion transport GO:0030001 289 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
negative regulation of signaling GO:0023057 157 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
head development GO:0060322 247 0.022
cellular component biogenesis GO:0044085 368 0.022
tissue development GO:0009888 252 0.022
negative regulation of metabolic process GO:0009892 331 0.022
proteolysis GO:0006508 175 0.022
regulation of neuron apoptotic process GO:0043523 83 0.022
negative regulation of molecular function GO:0044092 133 0.022
oxidation reduction process GO:0055114 304 0.022
response to molecule of fungal origin GO:0002238 3 0.021
lipid biosynthetic process GO:0008610 128 0.021
single organism cell adhesion GO:0098602 46 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
cellular homeostasis GO:0019725 252 0.021
regulation of body fluid levels GO:0050878 90 0.021
divalent inorganic cation transport GO:0072511 134 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
axon development GO:0061564 96 0.021
carbohydrate metabolic process GO:0005975 130 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of map kinase activity GO:0043405 53 0.021
regulation of transcription dna templated GO:0006355 374 0.021
response to axon injury GO:0048678 59 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
ribonucleoside triphosphate metabolic process GO:0009199 141 0.020
regulation of blood pressure GO:0008217 83 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
cell projection morphogenesis GO:0048858 123 0.020
regulation of membrane potential GO:0042391 110 0.020
divalent metal ion transport GO:0070838 132 0.020
cell communication involved in cardiac conduction GO:0086065 2 0.020
response to nutrient GO:0007584 248 0.020
lipid metabolic process GO:0006629 283 0.020
protein transport GO:0015031 132 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
atp metabolic process GO:0046034 72 0.020
brain development GO:0007420 247 0.020
purine nucleotide catabolic process GO:0006195 136 0.020
organic anion transport GO:0015711 132 0.020
cell part morphogenesis GO:0032990 123 0.019
positive regulation of protein kinase activity GO:0045860 73 0.019
secretion by cell GO:0032940 248 0.019
regulation of mapk cascade GO:0043408 116 0.019
synapse organization GO:0050808 46 0.019
positive regulation of developmental process GO:0051094 283 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
response to external biotic stimulus GO:0043207 221 0.019
muscle contraction GO:0006936 88 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
neuron projection development GO:0031175 273 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
vascular process in circulatory system GO:0003018 96 0.019
response to mechanical stimulus GO:0009612 134 0.019
multicellular organism reproduction GO:0032504 233 0.019
cellular response to peptide GO:1901653 133 0.018
protein localization GO:0008104 191 0.018
macromolecule localization GO:0033036 252 0.018
smooth muscle cell proliferation GO:0048659 77 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
ion homeostasis GO:0050801 212 0.018
muscle system process GO:0003012 115 0.018
alcohol metabolic process GO:0006066 77 0.018
response to monosaccharide GO:0034284 159 0.018
positive regulation of protein modification process GO:0031401 142 0.018
tube development GO:0035295 89 0.018
cellular response to oxidative stress GO:0034599 76 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
cellular ion homeostasis GO:0006873 184 0.017
response to lipopolysaccharide GO:0032496 191 0.017
positive regulation of defense response GO:0031349 37 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
nucleoside monophosphate metabolic process GO:0009123 93 0.017
single organism reproductive process GO:0044702 297 0.017
multicellular organism growth GO:0035264 1 0.017
cellular chemical homeostasis GO:0055082 247 0.017
response to peptide GO:1901652 292 0.017
multicellular organismal homeostasis GO:0048871 49 0.017
regulation of nervous system development GO:0051960 264 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
regulation of response to stress GO:0080134 126 0.017
axis specification GO:0009798 4 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
positive regulation of protein transport GO:0051222 41 0.016
protein complex assembly GO:0006461 263 0.016
regulation of establishment of protein localization GO:0070201 69 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
nucleoside catabolic process GO:0009164 126 0.016
negative regulation of gene expression GO:0010629 199 0.016
response to hexose GO:0009746 144 0.016
peptidyl amino acid modification GO:0018193 126 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
neuron apoptotic process GO:0051402 88 0.016
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.016
cholesterol homeostasis GO:0042632 3 0.016
establishment of protein localization GO:0045184 141 0.016
regulation of protein localization GO:0032880 81 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
reproduction GO:0000003 245 0.015
purine containing compound metabolic process GO:0072521 253 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
regulation of response to external stimulus GO:0032101 106 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of cell development GO:0010720 176 0.015
cellular response to lipid GO:0071396 201 0.015
nucleotide catabolic process GO:0009166 139 0.015
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
regulation of muscle contraction GO:0006937 53 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
mrna transcription GO:0009299 2 0.015
cell growth GO:0016049 104 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
regulation of defense response GO:0031347 68 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
response to glucose GO:0009749 136 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
mapk cascade GO:0000165 140 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
cell type specific apoptotic process GO:0097285 134 0.015
aromatic compound catabolic process GO:0019439 168 0.015
developmental process involved in reproduction GO:0003006 159 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
regulation of organelle organization GO:0033043 80 0.014
response to hydrogen peroxide GO:0042542 89 0.014
positive regulation of nervous system development GO:0051962 178 0.014
regulation of hormone levels GO:0010817 187 0.014
response to cytokine GO:0034097 215 0.014
negative regulation of developmental process GO:0051093 125 0.014
regulation of inflammatory response GO:0050727 48 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
chemosensory behavior GO:0007635 2 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
regulation of dna metabolic process GO:0051052 60 0.014
nucleotide metabolic process GO:0009117 279 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
sexual reproduction GO:0019953 148 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of secretion GO:0051047 140 0.014
regulation of metal ion transport GO:0010959 118 0.014
cellular cation homeostasis GO:0030003 180 0.014
dna metabolic process GO:0006259 96 0.014
multicellular organismal signaling GO:0035637 44 0.014
aging GO:0007568 241 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
negative regulation of signal transduction GO:0009968 83 0.013
response to toxic substance GO:0009636 133 0.013
positive regulation of molecular function GO:0044093 230 0.013
cation transport GO:0006812 382 0.013
regulation of protein transport GO:0051223 68 0.013
neuron projection morphogenesis GO:0048812 122 0.013
growth GO:0040007 165 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
cellular protein localization GO:0034613 122 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
immune system process GO:0002376 204 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
purine nucleoside monophosphate catabolic process GO:0009128 55 0.013
striated muscle contraction GO:0006941 44 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
intracellular protein transport GO:0006886 79 0.013
gamete generation GO:0007276 124 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
negative regulation of cell death GO:0060548 229 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
response to oxidative stress GO:0006979 186 0.013
gastrulation GO:0007369 2 0.012
regulation of ion transport GO:0043269 245 0.012
single organism organelle organization GO:1902589 180 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
regulation of catabolic process GO:0009894 113 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
gliogenesis GO:0042063 93 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
nitrogen compound transport GO:0071705 229 0.012
regulation of muscle system process GO:0090257 79 0.012
fatty acid biosynthetic process GO:0006633 33 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
lipid transport GO:0006869 61 0.012
rhythmic process GO:0048511 156 0.012
synaptic transmission GO:0007268 235 0.012
cation homeostasis GO:0055080 195 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of cell projection organization GO:0031344 175 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
regulation of blood circulation GO:1903522 110 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
behavior GO:0007610 205 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
response to ethanol GO:0045471 162 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
anion transport GO:0006820 178 0.011
spermatogenesis GO:0007283 99 0.011
regulation of tube size GO:0035150 89 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
regulation of homeostatic process GO:0032844 101 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
cytoplasmic transport GO:0016482 115 0.011
transmission of nerve impulse GO:0019226 42 0.011
sterol homeostasis GO:0055092 3 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
cellular amino acid biosynthetic process GO:0008652 32 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
smooth muscle cell migration GO:0014909 36 0.010
positive regulation of phagocytosis engulfment GO:0060100 4 0.010
cytokine production GO:0001816 61 0.010
regulation of growth GO:0040008 105 0.010
regulation of b cell differentiation GO:0045577 1 0.010
cellular response to acid chemical GO:0071229 75 0.010
metal ion homeostasis GO:0055065 186 0.010
positive regulation of kinase activity GO:0033674 77 0.010
response to progesterone GO:0032570 48 0.010
cardiac muscle contraction GO:0060048 27 0.010
response to peptide hormone GO:0043434 278 0.010
eye morphogenesis GO:0048592 4 0.010
single organism intracellular transport GO:1902582 166 0.010
positive regulation of transferase activity GO:0051347 81 0.010
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.010
gap junction assembly GO:0016264 2 0.010
heart morphogenesis GO:0003007 3 0.010
heart process GO:0003015 57 0.010

Ttc7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.012