Rattus norvegicus

34 known processes

Pmvk

phosphomevalonate kinase

(Aliases: MGC105660)

Pmvk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism biosynthetic process GO:0044711 342 0.094
lipid biosynthetic process GO:0008610 128 0.084
lipid metabolic process GO:0006629 283 0.075
carboxylic acid metabolic process GO:0019752 289 0.063
organic acid metabolic process GO:0006082 292 0.054
small molecule biosynthetic process GO:0044283 124 0.047
negative regulation of metabolic process GO:0009892 331 0.046
catabolic process GO:0009056 351 0.046
organic substance catabolic process GO:1901575 316 0.045
organophosphate biosynthetic process GO:0090407 143 0.042
single organism catabolic process GO:0044712 283 0.041
programmed cell death GO:0012501 392 0.039
cellular component biogenesis GO:0044085 368 0.039
oxoacid metabolic process GO:0043436 290 0.039
organelle organization GO:0006996 266 0.039
organophosphate metabolic process GO:0019637 370 0.037
single organism organelle organization GO:1902589 180 0.036
apoptotic process GO:0006915 381 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
regulation of cellular ketone metabolic process GO:0010565 27 0.034
cofactor metabolic process GO:0051186 95 0.034
regulation of cell proliferation GO:0042127 359 0.032
single organism reproductive process GO:0044702 297 0.032
regulation of protein metabolic process GO:0051246 289 0.032
cellular ketone metabolic process GO:0042180 51 0.031
reproduction GO:0000003 245 0.029
cellular lipid metabolic process GO:0044255 208 0.029
reproductive process GO:0022414 372 0.028
multicellular organism reproduction GO:0032504 233 0.028
head development GO:0060322 247 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
response to acid chemical GO:0001101 222 0.027
cellular amine metabolic process GO:0044106 38 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.025
negative regulation of cell death GO:0060548 229 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
monocarboxylic acid metabolic process GO:0032787 152 0.025
nucleotide metabolic process GO:0009117 279 0.025
cellular component assembly GO:0022607 360 0.025
central nervous system development GO:0007417 311 0.025
cellular catabolic process GO:0044248 295 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
regulation of cellular component organization GO:0051128 368 0.024
amine metabolic process GO:0009308 38 0.024
transcription dna templated GO:0006351 377 0.024
neuron differentiation GO:0030182 368 0.023
protein phosphorylation GO:0006468 345 0.023
response to external biotic stimulus GO:0043207 221 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
negative regulation of biosynthetic process GO:0009890 168 0.022
regulation of catalytic activity GO:0050790 304 0.022
positive regulation of molecular function GO:0044093 230 0.022
regulation of programmed cell death GO:0043067 341 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
multi organism reproductive process GO:0044703 262 0.022
regulation of rna metabolic process GO:0051252 391 0.021
response to biotic stimulus GO:0009607 226 0.021
ras protein signal transduction GO:0007265 29 0.021
purine containing compound metabolic process GO:0072521 253 0.021
aging GO:0007568 241 0.021
intracellular signal transduction GO:0035556 314 0.021
rna biosynthetic process GO:0032774 380 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
regulation of molecular function GO:0065009 398 0.020
macromolecular complex assembly GO:0065003 273 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
cell cell signaling GO:0007267 335 0.020
regulation of hormone levels GO:0010817 187 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
regulation of transcription dna templated GO:0006355 374 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
protein complex subunit organization GO:0071822 302 0.019
fatty acid metabolic process GO:0006631 99 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
regulation of cell differentiation GO:0045595 320 0.019
regulation of signal transduction GO:0009966 318 0.019
protein complex biogenesis GO:0070271 263 0.019
response to wounding GO:0009611 254 0.019
response to extracellular stimulus GO:0009991 380 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
protein complex assembly GO:0006461 263 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
rna metabolic process GO:0016070 406 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
brain development GO:0007420 247 0.018
response to nutrient levels GO:0031667 370 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
negative regulation of gene expression GO:0010629 199 0.018
cellular response to nitrogen compound GO:1901699 210 0.017
response to peptide hormone GO:0043434 278 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
sexual reproduction GO:0019953 148 0.017
ion transmembrane transport GO:0034220 365 0.017
regulation of cell development GO:0060284 263 0.017
homeostatic process GO:0042592 331 0.017
transmembrane transport GO:0055085 412 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
cation transport GO:0006812 382 0.017
regulation of organelle organization GO:0033043 80 0.016
response to inorganic substance GO:0010035 377 0.016
nucleic acid templated transcription GO:0097659 379 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
response to radiation GO:0009314 137 0.016
gamete generation GO:0007276 124 0.016
tissue development GO:0009888 252 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
secretion GO:0046903 307 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
positive regulation of developmental process GO:0051094 283 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
ion homeostasis GO:0050801 212 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
secretion by cell GO:0032940 248 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
response to metal ion GO:0010038 253 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
oxidation reduction process GO:0055114 304 0.015
regulation of apoptotic process GO:0042981 335 0.015
alcohol metabolic process GO:0006066 77 0.015
cell type specific apoptotic process GO:0097285 134 0.015
heart morphogenesis GO:0003007 3 0.015
neuron development GO:0048666 286 0.015
nucleoside metabolic process GO:0009116 179 0.015
organic acid biosynthetic process GO:0016053 83 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
regulation of phosphorylation GO:0042325 248 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of catabolic process GO:0009894 113 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
cellular chemical homeostasis GO:0055082 247 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
response to ketone GO:1901654 182 0.014
cell projection organization GO:0030030 302 0.014
cellular response to stress GO:0033554 269 0.014
cellular component movement GO:0006928 248 0.014
response to decreased oxygen levels GO:0036293 237 0.014
positive regulation of signaling GO:0023056 270 0.014
regulation of ion transport GO:0043269 245 0.014
cation homeostasis GO:0055080 195 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
locomotion GO:0040011 237 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
cellular response to lipid GO:0071396 201 0.013
regulation of nervous system development GO:0051960 264 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of cell communication GO:0010647 271 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
response to oxygen levels GO:0070482 265 0.013
positive regulation of cell death GO:0010942 184 0.013
response to ethanol GO:0045471 162 0.013
positive regulation of cell development GO:0010720 176 0.013
purine containing compound catabolic process GO:0072523 138 0.013
phospholipid biosynthetic process GO:0008654 29 0.013
reproductive structure development GO:0048608 128 0.013
protein oligomerization GO:0051259 191 0.013
neuron projection development GO:0031175 273 0.012
single organism behavior GO:0044708 130 0.012
immune system process GO:0002376 204 0.012
blood circulation GO:0008015 183 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
cell cycle checkpoint GO:0000075 2 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
negative regulation of molecular function GO:0044092 133 0.012
cellular homeostasis GO:0019725 252 0.012
regulation of neurogenesis GO:0050767 247 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
hormone transport GO:0009914 121 0.012
cellular cation homeostasis GO:0030003 180 0.012
growth GO:0040007 165 0.012
single organism intracellular transport GO:1902582 166 0.012
carbohydrate metabolic process GO:0005975 130 0.012
circulatory system development GO:0072359 134 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of protein modification process GO:0031399 194 0.012
gonad development GO:0008406 104 0.012
circulatory system process GO:0003013 183 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
signal release GO:0023061 145 0.012
regulation of system process GO:0044057 208 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
amide transport GO:0042886 105 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
developmental process involved in reproduction GO:0003006 159 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of lipid biosynthetic process GO:0046890 38 0.011
chemical homeostasis GO:0048878 292 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
embryonic pattern specification GO:0009880 1 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
regulation of secretion GO:0051046 224 0.011
reproductive system development GO:0061458 128 0.011
action potential GO:0001508 54 0.011
macromolecule localization GO:0033036 252 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
response to lipopolysaccharide GO:0032496 191 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
response to cytokine GO:0034097 215 0.011
developmental growth GO:0048589 100 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
spermatogenesis GO:0007283 99 0.011
response to fatty acid GO:0070542 65 0.011
axis specification GO:0009798 4 0.011
positive regulation of gene expression GO:0010628 244 0.011
response to bacterium GO:0009617 200 0.011
regulation of cell growth GO:0001558 85 0.011
response to monosaccharide GO:0034284 159 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of metal ion transport GO:0010959 118 0.011
response to hypoxia GO:0001666 231 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
sex differentiation GO:0007548 113 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
male gamete generation GO:0048232 99 0.010
response to growth factor GO:0070848 189 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
regeneration GO:0031099 163 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
neuronal action potential GO:0019228 35 0.010
regulation of membrane potential GO:0042391 110 0.010
isoprenoid metabolic process GO:0006720 45 0.010
response to corticosteroid GO:0031960 235 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
regulation of response to stress GO:0080134 126 0.010
proteolysis GO:0006508 175 0.010
behavior GO:0007610 205 0.010
isoprenoid biosynthetic process GO:0008299 12 0.010
response to other organism GO:0051707 220 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
cell migration GO:0016477 197 0.010

Pmvk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017