Rattus norvegicus

0 known processes

Phb2

prohibitin 2

(Aliases: Bcap37,Bap37,Bap-37,Bap,Bcap27)

Phb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound biosynthetic process GO:1901566 167 0.167
macromolecular complex subunit organization GO:0043933 339 0.151
single organism biosynthetic process GO:0044711 342 0.127
organophosphate metabolic process GO:0019637 370 0.118
negative regulation of programmed cell death GO:0043069 183 0.095
cellular response to oxygen containing compound GO:1901701 386 0.091
response to peptide hormone GO:0043434 278 0.090
regulation of nervous system development GO:0051960 264 0.089
aging GO:0007568 241 0.088
negative regulation of cell death GO:0060548 229 0.078
cellular response to stress GO:0033554 269 0.078
negative regulation of cellular metabolic process GO:0031324 281 0.076
macromolecular complex assembly GO:0065003 273 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.075
cellular catabolic process GO:0044248 295 0.070
cell cycle GO:0007049 101 0.068
regulation of programmed cell death GO:0043067 341 0.067
regulation of cell proliferation GO:0042127 359 0.064
regulation of cellular protein metabolic process GO:0032268 267 0.062
protein complex subunit organization GO:0071822 302 0.060
reproduction GO:0000003 245 0.059
regeneration GO:0031099 163 0.059
nucleoside diphosphate metabolic process GO:0009132 14 0.059
regulation of cellular component organization GO:0051128 368 0.058
response to oxidative stress GO:0006979 186 0.056
catabolic process GO:0009056 351 0.056
positive regulation of multicellular organismal process GO:0051240 387 0.055
organic acid metabolic process GO:0006082 292 0.055
negative regulation of metabolic process GO:0009892 331 0.054
positive regulation of neurogenesis GO:0050769 165 0.051
transcription dna templated GO:0006351 377 0.050
regulation of cell differentiation GO:0045595 320 0.050
protein complex assembly GO:0006461 263 0.049
neuron differentiation GO:0030182 368 0.049
protein complex biogenesis GO:0070271 263 0.049
cofactor metabolic process GO:0051186 95 0.049
regulation of multicellular organismal development GO:2000026 376 0.048
oxidation reduction process GO:0055114 304 0.048
response to peptide GO:1901652 292 0.048
organic substance catabolic process GO:1901575 316 0.047
negative regulation of apoptotic process GO:0043066 181 0.045
positive regulation of cell proliferation GO:0008284 249 0.043
spindle organization GO:0007051 2 0.042
regulation of molecular function GO:0065009 398 0.042
regulation of phosphate metabolic process GO:0019220 349 0.040
positive regulation of nucleic acid templated transcription GO:1903508 197 0.040
cellular response to lipid GO:0071396 201 0.040
regulation of cell development GO:0060284 263 0.038
reproductive process GO:0022414 372 0.038
regulation of hydrolase activity GO:0051336 143 0.038
neuron projection development GO:0031175 273 0.038
negative regulation of signaling GO:0023057 157 0.038
regulation of protein metabolic process GO:0051246 289 0.037
organ regeneration GO:0031100 101 0.037
nucleoside phosphate metabolic process GO:0006753 283 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
rna metabolic process GO:0016070 406 0.036
regulation of apoptotic process GO:0042981 335 0.036
single organism organelle organization GO:1902589 180 0.035
positive regulation of rna metabolic process GO:0051254 203 0.035
organelle organization GO:0006996 266 0.035
cellular component assembly GO:0022607 360 0.034
regulation of cellular localization GO:0060341 263 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
response to purine containing compound GO:0014074 126 0.033
response to inorganic substance GO:0010035 377 0.033
response to hypoxia GO:0001666 231 0.032
oxoacid metabolic process GO:0043436 290 0.032
protein phosphorylation GO:0006468 345 0.032
organophosphate biosynthetic process GO:0090407 143 0.031
regulation of neuron projection development GO:0010975 161 0.031
nucleic acid templated transcription GO:0097659 379 0.031
regulation of rna metabolic process GO:0051252 391 0.030
regulation of neuron differentiation GO:0045664 208 0.030
cell projection organization GO:0030030 302 0.029
ion transmembrane transport GO:0034220 365 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
programmed cell death GO:0012501 392 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.028
protein localization GO:0008104 191 0.028
response to carbohydrate GO:0009743 183 0.028
positive regulation of cell death GO:0010942 184 0.028
response to acid chemical GO:0001101 222 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.027
negative regulation of response to stimulus GO:0048585 155 0.027
pyrimidine nucleotide biosynthetic process GO:0006221 9 0.027
locomotion GO:0040011 237 0.027
nucleoside phosphate biosynthetic process GO:1901293 102 0.027
nucleotide biosynthetic process GO:0009165 98 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
apoptotic process GO:0006915 381 0.027
response to decreased oxygen levels GO:0036293 237 0.026
positive regulation of developmental process GO:0051094 283 0.026
response to tumor cell GO:0002347 4 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
response to glucose GO:0009749 136 0.025
cation transmembrane transport GO:0098655 263 0.025
central nervous system development GO:0007417 311 0.025
transmembrane transport GO:0055085 412 0.025
regulation of nucleic acid templated transcription GO:1903506 380 0.024
translation GO:0006412 35 0.024
nucleotide metabolic process GO:0009117 279 0.024
cellular component movement GO:0006928 248 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
cellular macromolecule localization GO:0070727 122 0.024
homeostatic process GO:0042592 331 0.024
regulation of signal transduction GO:0009966 318 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
cellular component biogenesis GO:0044085 368 0.023
multicellular organism reproduction GO:0032504 233 0.022
response to oxygen levels GO:0070482 265 0.022
gland development GO:0048732 155 0.022
macromolecule localization GO:0033036 252 0.022
response to ketone GO:1901654 182 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
intracellular transport GO:0046907 185 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
multicellular organismal reproductive process GO:0048609 233 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
response to extracellular stimulus GO:0009991 380 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
rna biosynthetic process GO:0032774 380 0.021
response to hexose GO:0009746 144 0.021
negative regulation of transport GO:0051051 136 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
negative regulation of transcription dna templated GO:0045892 116 0.021
regulation of transcription dna templated GO:0006355 374 0.021
microtubule organizing center organization GO:0031023 1 0.020
positive regulation of cell development GO:0010720 176 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
macromolecule catabolic process GO:0009057 58 0.020
regulation of catalytic activity GO:0050790 304 0.020
single organism catabolic process GO:0044712 283 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
lipid metabolic process GO:0006629 283 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
cellular amine metabolic process GO:0044106 38 0.019
ribose phosphate biosynthetic process GO:0046390 87 0.019
mitotic spindle organization GO:0007052 2 0.019
intracellular signal transduction GO:0035556 314 0.019
positive regulation of transport GO:0051050 245 0.019
response to biotic stimulus GO:0009607 226 0.019
cellular response to peptide GO:1901653 133 0.019
response to amine GO:0014075 46 0.019
cellular chemical homeostasis GO:0055082 247 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
response to monosaccharide GO:0034284 159 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
response to organophosphorus GO:0046683 102 0.018
cation homeostasis GO:0055080 195 0.018
purine containing compound biosynthetic process GO:0072522 85 0.018
response to nutrient levels GO:0031667 370 0.018
negative regulation of cell communication GO:0010648 158 0.018
positive regulation of gene expression GO:0010628 244 0.018
single organism intracellular transport GO:1902582 166 0.018
pyrimidine ribonucleotide metabolic process GO:0009218 5 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.017
response to ethanol GO:0045471 162 0.017
purine ribonucleoside biosynthetic process GO:0046129 21 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
defense response GO:0006952 194 0.017
positive regulation of signaling GO:0023056 270 0.017
chemical homeostasis GO:0048878 292 0.017
positive regulation of molecular function GO:0044093 230 0.017
proteolysis GO:0006508 175 0.017
cytokine production GO:0001816 61 0.017
cell motility GO:0048870 202 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
neuron development GO:0048666 286 0.017
positive regulation of nervous system development GO:0051962 178 0.017
negative regulation of developmental process GO:0051093 125 0.017
multi organism reproductive process GO:0044703 262 0.017
growth GO:0040007 165 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regulation of cell projection organization GO:0031344 175 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
response to camp GO:0051591 91 0.016
purine containing compound metabolic process GO:0072521 253 0.016
protein processing GO:0016485 68 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
response to alkaloid GO:0043279 132 0.016
anterior posterior pattern specification GO:0009952 1 0.016
cellular ketone metabolic process GO:0042180 51 0.015
cellular lipid metabolic process GO:0044255 208 0.015
single organism reproductive process GO:0044702 297 0.015
cellular protein localization GO:0034613 122 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
regulation of neurogenesis GO:0050767 247 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
localization of cell GO:0051674 202 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
regulation of neuron death GO:1901214 115 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
brain development GO:0007420 247 0.014
negative regulation of innate immune response GO:0045824 4 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
ctp biosynthetic process GO:0006241 1 0.014
response to fatty acid GO:0070542 65 0.014
regulation of protein modification process GO:0031399 194 0.014
ion homeostasis GO:0050801 212 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
reproductive system development GO:0061458 128 0.014
heterocycle catabolic process GO:0046700 167 0.014
male gamete generation GO:0048232 99 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
protein oligomerization GO:0051259 191 0.014
positive regulation of epidermis development GO:0045684 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
response to cytokine GO:0034097 215 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
reproductive structure development GO:0048608 128 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
metal ion transport GO:0030001 289 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
response to external biotic stimulus GO:0043207 221 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
development of primary sexual characteristics GO:0045137 107 0.013
amine metabolic process GO:0009308 38 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
immune system process GO:0002376 204 0.013
cellular macromolecular complex assembly GO:0034622 58 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
positive regulation of cell communication GO:0010647 271 0.012
cellular response to acid chemical GO:0071229 75 0.012
synaptic transmission GO:0007268 235 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
aromatic compound catabolic process GO:0019439 168 0.012
dna metabolic process GO:0006259 96 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cellular protein complex assembly GO:0043623 44 0.012
head development GO:0060322 247 0.012
cytoplasmic transport GO:0016482 115 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
coenzyme metabolic process GO:0006732 86 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of phosphorylation GO:0042325 248 0.012
response to lipopolysaccharide GO:0032496 191 0.012
developmental process involved in reproduction GO:0003006 159 0.011
cell cycle process GO:0022402 57 0.011
heart development GO:0007507 72 0.011
centrosome organization GO:0051297 1 0.011
hepaticobiliary system development GO:0061008 90 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
nucleoside metabolic process GO:0009116 179 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
organophosphate catabolic process GO:0046434 148 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
cell activation GO:0001775 97 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
pyridine containing compound metabolic process GO:0072524 32 0.011
immune system development GO:0002520 41 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
response to reactive oxygen species GO:0000302 120 0.011
secretion GO:0046903 307 0.010
regulation of growth GO:0040008 105 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
nitrogen compound transport GO:0071705 229 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
cellular ion homeostasis GO:0006873 184 0.010
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010

Phb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.020
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020