Rattus norvegicus

254 known processes

Nme2

non-metastatic cells 2, protein (NM23B) expressed in

(Aliases: p18-12d,NDKB)

Nme2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pyrimidine ribonucleotide metabolic process GO:0009218 5 0.606
negative regulation of cell death GO:0060548 229 0.388
Human
pyrimidine ribonucleoside triphosphate biosynthetic process GO:0009209 2 0.268
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 3 0.268
response to oxidative stress GO:0006979 186 0.241
rna metabolic process GO:0016070 406 0.179
Human
negative regulation of metabolic process GO:0009892 331 0.166
Rat
regulation of cell migration GO:0030334 128 0.153
pyrimidine nucleotide biosynthetic process GO:0006221 9 0.143
response to extracellular stimulus GO:0009991 380 0.130
response to peptide GO:1901652 292 0.121
regulation of cell development GO:0060284 263 0.102
central nervous system development GO:0007417 311 0.102
Rat
inorganic cation transmembrane transport GO:0098662 202 0.097
cellular response to oxygen containing compound GO:1901701 386 0.097
pyrimidine ribonucleotide biosynthetic process GO:0009220 5 0.095
pyrimidine nucleoside biosynthetic process GO:0046134 5 0.094
pyrimidine nucleoside triphosphate metabolic process GO:0009147 4 0.092
negative regulation of cellular metabolic process GO:0031324 281 0.087
response to peptide hormone GO:0043434 278 0.084
inorganic ion transmembrane transport GO:0098660 229 0.079
regulation of molecular function GO:0065009 398 0.074
ctp metabolic process GO:0046036 1 0.074
homeostatic process GO:0042592 331 0.074
regulation of phosphorylation GO:0042325 248 0.072
cellular response to stress GO:0033554 269 0.069
negative regulation of multicellular organismal process GO:0051241 203 0.067
regulation of cell proliferation GO:0042127 359 0.067
Human
organonitrogen compound biosynthetic process GO:1901566 167 0.064
cellular amino acid metabolic process GO:0006520 107 0.063
cellular component biogenesis GO:0044085 368 0.062
response to nutrient levels GO:0031667 370 0.060
response to acid chemical GO:0001101 222 0.060
positive regulation of developmental process GO:0051094 283 0.058
positive regulation of multicellular organismal process GO:0051240 387 0.056
cellular homeostasis GO:0019725 252 0.055
ctp biosynthetic process GO:0006241 1 0.053
metal ion transport GO:0030001 289 0.053
cation transport GO:0006812 382 0.050
response to ketone GO:1901654 182 0.050
Rat
regulation of signal transduction GO:0009966 318 0.050
cation transmembrane transport GO:0098655 263 0.050
aging GO:0007568 241 0.050
chemical homeostasis GO:0048878 292 0.049
monovalent inorganic cation transport GO:0015672 172 0.049
transmembrane transport GO:0055085 412 0.047
response to glucose GO:0009749 136 0.045
locomotion GO:0040011 237 0.044
response to wounding GO:0009611 254 0.042
positive regulation of biosynthetic process GO:0009891 319 0.042
apoptotic process GO:0006915 381 0.042
Human
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.041
oxoacid metabolic process GO:0043436 290 0.040
cation homeostasis GO:0055080 195 0.040
protein complex subunit organization GO:0071822 302 0.040
regulation of camp metabolic process GO:0030814 43 0.039
nucleic acid templated transcription GO:0097659 379 0.037
Human
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
programmed cell death GO:0012501 392 0.035
Human
protein complex assembly GO:0006461 263 0.035
regulation of neuron death GO:1901214 115 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
response to nutrient GO:0007584 248 0.035
intracellular transport GO:0046907 185 0.034
cytoplasmic transport GO:0016482 115 0.034
neuron death GO:0070997 127 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
negative regulation of cell communication GO:0010648 158 0.032
positive regulation of camp metabolic process GO:0030816 31 0.031
pyrimidine nucleotide metabolic process GO:0006220 9 0.031
single organism intracellular transport GO:1902582 166 0.031
negative regulation of leukocyte differentiation GO:1902106 5 0.030
purine nucleotide biosynthetic process GO:0006164 83 0.030
organic acid metabolic process GO:0006082 292 0.030
regulation of ion transport GO:0043269 245 0.030
negative regulation of molecular function GO:0044092 133 0.029
protein phosphorylation GO:0006468 345 0.029
positive regulation of transport GO:0051050 245 0.029
regulation of programmed cell death GO:0043067 341 0.029
Human
regulation of cellular protein metabolic process GO:0032268 267 0.028
organophosphate metabolic process GO:0019637 370 0.027
regulation of transcription dna templated GO:0006355 374 0.027
Human
regulation of rna biosynthetic process GO:2001141 381 0.027
Human
negative regulation of apoptotic process GO:0043066 181 0.027
Human
cyclic purine nucleotide metabolic process GO:0052652 62 0.026
regulation of cellular component organization GO:0051128 368 0.026
protein oligomerization GO:0051259 191 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
head development GO:0060322 247 0.024
Rat
response to lipopolysaccharide GO:0032496 191 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
regulation of cellular component movement GO:0051270 150 0.023
cellular chemical homeostasis GO:0055082 247 0.023
response to reactive oxygen species GO:0000302 120 0.023
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.023
secretion by tissue GO:0032941 37 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
rna biosynthetic process GO:0032774 380 0.022
Human
multi organism reproductive process GO:0044703 262 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
Rat
myeloid leukocyte differentiation GO:0002573 20 0.021
positive regulation of cell development GO:0010720 176 0.021
carboxylic acid metabolic process GO:0019752 289 0.020
cell migration GO:0016477 197 0.020
neuron differentiation GO:0030182 368 0.020
nucleotide phosphorylation GO:0046939 8 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
negative regulation of cell proliferation GO:0008285 119 0.020
protein complex biogenesis GO:0070271 263 0.020
amine metabolic process GO:0009308 38 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
regulation of cell differentiation GO:0045595 320 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
positive regulation of neurogenesis GO:0050769 165 0.019
telencephalon development GO:0021537 62 0.019
Rat
regulation of nervous system development GO:0051960 264 0.019
regulation of kinase activity GO:0043549 117 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of transmembrane transporter activity GO:0022898 49 0.018
response to decreased oxygen levels GO:0036293 237 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
transcription dna templated GO:0006351 377 0.018
Human
purine nucleotide metabolic process GO:0006163 229 0.017
response to inorganic substance GO:0010035 377 0.017
cellular component movement GO:0006928 248 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
cellular ion homeostasis GO:0006873 184 0.017
spliceosomal complex assembly GO:0000245 2 0.017
response to hydrogen peroxide GO:0042542 89 0.017
ion transmembrane transport GO:0034220 365 0.017
cellular response to acid chemical GO:0071229 75 0.017
response to external biotic stimulus GO:0043207 221 0.017
nucleotide biosynthetic process GO:0009165 98 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
sequestering of calcium ion GO:0051208 8 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
single organism reproductive process GO:0044702 297 0.016
cellular response to hexose stimulus GO:0071331 65 0.015
negative regulation of developmental process GO:0051093 125 0.015
response to cytokine GO:0034097 215 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
Human
intracellular protein transport GO:0006886 79 0.015
brain development GO:0007420 247 0.015
Rat
mammary gland development GO:0030879 38 0.015
positive regulation of ion transport GO:0043270 94 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.015
Human
ribonucleotide metabolic process GO:0009259 231 0.015
negative regulation of catalytic activity GO:0043086 103 0.014
regulation of neuron projection development GO:0010975 161 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
defense response GO:0006952 194 0.014
positive regulation of cell death GO:0010942 184 0.014
response to hypoxia GO:0001666 231 0.013
macromolecule localization GO:0033036 252 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
body fluid secretion GO:0007589 41 0.013
response to organophosphorus GO:0046683 102 0.013
Rat
pyrimidine ribonucleoside biosynthetic process GO:0046132 5 0.013
cellular cation homeostasis GO:0030003 180 0.013
endocytic recycling GO:0032456 2 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of cellular localization GO:0060341 263 0.013
neuron development GO:0048666 286 0.013
molting cycle GO:0042303 3 0.013
cell activation GO:0001775 97 0.012
positive regulation of molecular function GO:0044093 230 0.012
peptidyl cysteine modification GO:0018198 2 0.012
ion homeostasis GO:0050801 212 0.012
regulation of nucleotide biosynthetic process GO:0030808 47 0.012
response to glucocorticoid GO:0051384 223 0.012
multicellular organism reproduction GO:0032504 233 0.012
response to camp GO:0051591 91 0.012
Rat
protein localization to cell surface GO:0034394 1 0.012
regulation of rna metabolic process GO:0051252 391 0.012
Human
regulation of apoptotic process GO:0042981 335 0.012
Human
purine nucleoside metabolic process GO:0042278 169 0.012
neuron projection development GO:0031175 273 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
macromolecular complex assembly GO:0065003 273 0.011
inflammatory response GO:0006954 150 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
secretion GO:0046903 307 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to hexose GO:0009746 144 0.011
regulation of cellular response to hypoxia GO:1900037 2 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of camp biosynthetic process GO:0030817 38 0.011
positive regulation of cell communication GO:0010647 271 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
growth GO:0040007 165 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.011
dorsal ventral pattern formation GO:0009953 4 0.010
reproduction GO:0000003 245 0.010
nucleoside metabolic process GO:0009116 179 0.010
reproductive process GO:0022414 372 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010
immune system process GO:0002376 204 0.010

Nme2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org