Rattus norvegicus

97 known processes

Otc

ornithine carbamoyltransferase

(Aliases: MGC108742)

Otc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gland development GO:0048732 155 0.725
response to peptide GO:1901652 292 0.663
liver development GO:0001889 90 0.579
cellular response to peptide hormone stimulus GO:0071375 120 0.513
halogenated hydrocarbon metabolic process GO:0042197 4 0.476
naphthalene containing compound metabolic process GO:0090420 2 0.467
alkaloid metabolic process GO:0009820 3 0.405
cellular hormone metabolic process GO:0034754 49 0.404
trichloroethylene metabolic process GO:0018979 1 0.383
hepaticobiliary system development GO:0061008 90 0.376
oxidation reduction process GO:0055114 304 0.352
oxoacid metabolic process GO:0043436 290 0.327
chlorinated hydrocarbon metabolic process GO:0042196 4 0.304
neutral lipid metabolic process GO:0006638 21 0.295
cellular response to organonitrogen compound GO:0071417 197 0.295
response to corticosteroid GO:0031960 235 0.289
response to xenobiotic stimulus GO:0009410 23 0.280
response to peptide hormone GO:0043434 278 0.273
cellular response to xenobiotic stimulus GO:0071466 19 0.264
carboxylic acid metabolic process GO:0019752 289 0.255
acylglycerol metabolic process GO:0006639 21 0.232
alpha amino acid metabolic process GO:1901605 71 0.224
response to glucocorticoid GO:0051384 223 0.201
isoprenoid metabolic process GO:0006720 45 0.197
organic substance catabolic process GO:1901575 316 0.193
response to insulin GO:0032868 133 0.186
pyridine containing compound metabolic process GO:0072524 32 0.182
response to nutrient levels GO:0031667 370 0.182
cellular response to peptide GO:1901653 133 0.181
response to ketone GO:1901654 182 0.175
cellular lipid metabolic process GO:0044255 208 0.175
nicotine metabolic process GO:0018933 1 0.166
xenobiotic metabolic process GO:0006805 19 0.166
catabolic process GO:0009056 351 0.161
drug catabolic process GO:0042737 1 0.161
exogenous drug catabolic process GO:0042738 1 0.160
isoquinoline alkaloid metabolic process GO:0033076 2 0.157
response to cesium ion GO:0010164 2 0.156
aromatic amino acid family catabolic process GO:0009074 7 0.156
monocarboxylic acid metabolic process GO:0032787 152 0.155
terpenoid metabolic process GO:0006721 37 0.154
protein homotrimerization GO:0070207 15 0.149
coenzyme metabolic process GO:0006732 86 0.146
triglyceride metabolic process GO:0006641 21 0.145
4 chlorobiphenyl metabolic process GO:0018880 1 0.141
diterpenoid metabolic process GO:0016101 33 0.140
biphenyl catabolic process GO:0070980 2 0.137
naphthalene metabolic process GO:0018931 2 0.135
aromatic amino acid family metabolic process GO:0009072 9 0.133
anatomical structure morphogenesis GO:0009653 298 0.132
single organism biosynthetic process GO:0044711 342 0.123
phenylpropanoid metabolic process GO:0009698 5 0.121
insecticide metabolic process GO:0017143 4 0.119
reproductive process GO:0022414 372 0.118
cellular response to nitrogen compound GO:1901699 210 0.116
xenobiotic catabolic process GO:0042178 7 0.115
response to zinc ion GO:0010043 39 0.114
response to extracellular stimulus GO:0009991 380 0.111
multi organism reproductive process GO:0044703 262 0.108
cellular response to steroid hormone stimulus GO:0071383 93 0.108
cellular catabolic process GO:0044248 295 0.106
organic acid metabolic process GO:0006082 292 0.104
response to organophosphorus GO:0046683 102 0.103
multi multicellular organism process GO:0044706 138 0.094
cellular response to corticosteroid stimulus GO:0071384 69 0.089
secondary metabolic process GO:0019748 15 0.088
indolalkylamine metabolic process GO:0006586 5 0.087
toxin catabolic process GO:0009407 1 0.085
coumarin metabolic process GO:0009804 5 0.085
toxin metabolic process GO:0009404 9 0.083
response to other organism GO:0051707 220 0.081
single organism catabolic process GO:0044712 283 0.080
cellular response to insulin stimulus GO:0032869 81 0.080
phenylpropanoid catabolic process GO:0046271 3 0.076
drug metabolic process GO:0017144 11 0.076
fibrinolysis GO:0042730 2 0.074
tryptophan metabolic process GO:0006568 5 0.074
estrogen catabolic process GO:0006711 1 0.073
response to camp GO:0051591 91 0.073
macromolecule localization GO:0033036 252 0.072
regulation of response to stress GO:0080134 126 0.072
cellular amino acid metabolic process GO:0006520 107 0.071
estrogen metabolic process GO:0008210 11 0.071
response to amino acid GO:0043200 75 0.069
organ regeneration GO:0031100 101 0.068
protein complex assembly GO:0006461 263 0.067
macromolecular complex assembly GO:0065003 273 0.067
cellular lipid catabolic process GO:0044242 37 0.067
response to ethanol GO:0045471 162 0.066
response to mercury ion GO:0046689 15 0.065
aromatic compound catabolic process GO:0019439 168 0.062
lipid metabolic process GO:0006629 283 0.062
cellular response to organic cyclic compound GO:0071407 202 0.059
intestinal absorption GO:0050892 3 0.059
response to transition metal nanoparticle GO:1990267 122 0.058
coumarin catabolic process GO:0046226 3 0.057
response to reactive oxygen species GO:0000302 120 0.057
fatty acid metabolic process GO:0006631 99 0.057
organonitrogen compound catabolic process GO:1901565 179 0.056
response to bacterium GO:0009617 200 0.056
coagulation GO:0050817 28 0.056
urea metabolic process GO:0019627 5 0.055
hormone metabolic process GO:0042445 69 0.055
steroid metabolic process GO:0008202 73 0.055
response to ddt GO:0046680 1 0.053
response to oxidative stress GO:0006979 186 0.053
response to metal ion GO:0010038 253 0.052
organic acid biosynthetic process GO:0016053 83 0.051
lipid catabolic process GO:0016042 46 0.051
lipid biosynthetic process GO:0008610 128 0.051
cellular component assembly GO:0022607 360 0.050
cellular response to lipid GO:0071396 201 0.050
female pregnancy GO:0007565 122 0.048
negative regulation of apoptotic process GO:0043066 181 0.048
cellular response to testosterone stimulus GO:0071394 5 0.047
cellular response to glucocorticoid stimulus GO:0071385 68 0.047
epoxygenase p450 pathway GO:0019373 1 0.047
rhythmic process GO:0048511 156 0.046
carbohydrate metabolic process GO:0005975 130 0.046
response to purine containing compound GO:0014074 126 0.045
response to external biotic stimulus GO:0043207 221 0.045
fatty acid derivative metabolic process GO:1901568 38 0.045
response to oxygen levels GO:0070482 265 0.045
cellular response to fluid shear stress GO:0071498 4 0.044
triglyceride catabolic process GO:0019433 3 0.043
androgen biosynthetic process GO:0006702 10 0.043
cofactor metabolic process GO:0051186 95 0.043
protein complex biogenesis GO:0070271 263 0.043
small molecule catabolic process GO:0044282 59 0.042
response to acetate GO:0010034 3 0.042
inner medullary collecting duct development GO:0072061 1 0.042
oxidative demethylation GO:0070989 2 0.042
response to molecule of bacterial origin GO:0002237 194 0.042
bile acid and bile salt transport GO:0015721 12 0.041
cellular response to oxygen containing compound GO:1901701 386 0.040
carboxylic acid catabolic process GO:0046395 49 0.040
multicellular organismal reproductive process GO:0048609 233 0.040
retinoid metabolic process GO:0001523 24 0.039
response to estrogen GO:0043627 232 0.039
cellular response to oxidative stress GO:0034599 76 0.039
positive regulation of response to stimulus GO:0048584 285 0.039
negative regulation of cell death GO:0060548 229 0.037
reactive oxygen species metabolic process GO:0072593 37 0.037
response to temperature stimulus GO:0009266 94 0.037
positive regulation of hydrolase activity GO:0051345 86 0.036
heterocycle catabolic process GO:0046700 167 0.036
cellular response to ethanol GO:0071361 13 0.035
hormone catabolic process GO:0042447 2 0.035
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.035
regulation of tolerance induction GO:0002643 2 0.034
regulation of apoptotic process GO:0042981 335 0.033
tolerance induction dependent upon immune response GO:0002461 2 0.033
single organism carbohydrate metabolic process GO:0044723 118 0.033
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.033
protein oligomerization GO:0051259 191 0.033
small molecule biosynthetic process GO:0044283 124 0.032
regulation of reactive oxygen species metabolic process GO:2000377 26 0.032
phenol containing compound metabolic process GO:0018958 30 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
response to inorganic substance GO:0010035 377 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.031
blood coagulation GO:0007596 26 0.031
positive regulation of tolerance induction GO:0002645 1 0.031
cellular response to ketone GO:1901655 51 0.031
hemostasis GO:0007599 26 0.031
organic cyclic compound catabolic process GO:1901361 175 0.030
response to testosterone GO:0033574 55 0.030
glycerolipid metabolic process GO:0046486 67 0.030
positive regulation of blood coagulation GO:0030194 4 0.030
cell projection organization GO:0030030 302 0.030
protein homooligomerization GO:0051260 91 0.030
vitamin transport GO:0051180 14 0.029
cellular modified amino acid metabolic process GO:0006575 61 0.029
cellular response to stress GO:0033554 269 0.028
regulation of protein maturation GO:1903317 50 0.028
negative regulation of metabolic process GO:0009892 331 0.028
circadian rhythm GO:0007623 88 0.028
negative regulation of response to stimulus GO:0048585 155 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
response to insecticide GO:0017085 21 0.027
arachidonic acid metabolic process GO:0019369 20 0.027
response to acid chemical GO:0001101 222 0.027
response to decreased oxygen levels GO:0036293 237 0.026
regulation of hydrolase activity GO:0051336 143 0.026
reproduction GO:0000003 245 0.026
dopamine metabolic process GO:0042417 12 0.026
response to toxic substance GO:0009636 133 0.026
regulation of extracellular matrix constituent secretion GO:0003330 2 0.025
cellular response to reactive oxygen species GO:0034614 55 0.025
organic acid catabolic process GO:0016054 49 0.025
retinal metabolic process GO:0042574 3 0.025
secondary metabolite catabolic process GO:0090487 1 0.025
growth GO:0040007 165 0.025
plasminogen activation GO:0031639 2 0.025
protein complex subunit organization GO:0071822 302 0.024
protein localization GO:0008104 191 0.024
retinoic acid metabolic process GO:0042573 13 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
4 nitrophenol metabolic process GO:0018960 1 0.023
cellular amine metabolic process GO:0044106 38 0.023
aging GO:0007568 241 0.023
response to wounding GO:0009611 254 0.022
extracellular matrix constituent secretion GO:0070278 4 0.022
amine catabolic process GO:0009310 9 0.022
cellular response to alcohol GO:0097306 87 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
regeneration GO:0031099 163 0.022
response to vitamin GO:0033273 131 0.021
steroid biosynthetic process GO:0006694 48 0.021
positive regulation of extracellular matrix organization GO:1903055 4 0.021
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.021
response to biotic stimulus GO:0009607 226 0.021
response to platinum ion GO:0070541 4 0.021
alpha amino acid catabolic process GO:1901606 20 0.021
regulation of vasculature development GO:1901342 44 0.021
response to nutrient GO:0007584 248 0.020
regulation of serine type endopeptidase activity GO:1900003 1 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
organophosphate metabolic process GO:0019637 370 0.020
cellular response to external stimulus GO:0071496 118 0.020
negative regulation of gene expression GO:0010629 199 0.019
indole containing compound metabolic process GO:0042430 11 0.019
sulfur compound metabolic process GO:0006790 70 0.019
lipid localization GO:0010876 62 0.019
catecholamine metabolic process GO:0006584 19 0.019
amine metabolic process GO:0009308 38 0.019
response to ionizing radiation GO:0010212 59 0.019
negative regulation of peptidase activity GO:0010466 38 0.019
response to sulfur dioxide GO:0010477 3 0.019
cellular sodium ion homeostasis GO:0006883 4 0.019
regulation of catalytic activity GO:0050790 304 0.019
neuron differentiation GO:0030182 368 0.019
negative regulation of protein maturation GO:1903318 47 0.019
regulation of cell projection organization GO:0031344 175 0.019
protein processing GO:0016485 68 0.018
long chain fatty acid metabolic process GO:0001676 32 0.018
developmental growth GO:0048589 100 0.018
icosanoid metabolic process GO:0006690 38 0.018
protein phosphorylation GO:0006468 345 0.018
multicellular organism reproduction GO:0032504 233 0.018
response to food GO:0032094 27 0.018
response to vitamin a GO:0033189 36 0.018
response to lipopolysaccharide GO:0032496 191 0.018
programmed cell death GO:0012501 392 0.018
epithelial cell proliferation GO:0050673 54 0.017
calcitriol biosynthetic process from calciol GO:0036378 2 0.017
phenol containing compound biosynthetic process GO:0046189 9 0.017
response to increased oxygen levels GO:0036296 45 0.017
regulation of body fluid levels GO:0050878 90 0.017
glycolytic process GO:0006096 17 0.017
lipid storage GO:0019915 1 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.017
apoptotic process GO:0006915 381 0.016
secondary alcohol metabolic process GO:1902652 2 0.016
biphenyl metabolic process GO:0018879 10 0.016
cellular biogenic amine metabolic process GO:0006576 30 0.016
monocarboxylic acid catabolic process GO:0072329 28 0.016
pyridine nucleotide metabolic process GO:0019362 28 0.016
unsaturated fatty acid metabolic process GO:0033559 39 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
regulation of molecular function GO:0065009 398 0.016
isoprenoid biosynthetic process GO:0008299 12 0.016
chylomicron remodeling GO:0034371 1 0.016
defense response GO:0006952 194 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
demethylation GO:0070988 7 0.016
cellular response to iron ion starvation GO:0010106 1 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
cholesterol transport GO:0030301 5 0.015
protein maturation GO:0051604 68 0.015
catenin import into nucleus GO:0035411 1 0.015
negative regulation of innate immune response GO:0045824 4 0.015
regulation of tolerance induction to nonself antigen GO:0002655 1 0.015
reactive nitrogen species metabolic process GO:2001057 1 0.015
artery smooth muscle contraction GO:0014824 4 0.015
cellular ketone metabolic process GO:0042180 51 0.015
cellular amino acid catabolic process GO:0009063 21 0.015
cellular response to camp GO:0071320 26 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.014
synaptic transmission GO:0007268 235 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
response to mineralocorticoid GO:0051385 49 0.014
response to alkaloid GO:0043279 132 0.014
maintenance of location GO:0051235 17 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
response to cadmium ion GO:0046686 35 0.014
negative regulation of serine type peptidase activity GO:1902572 1 0.014
cellular biogenic amine catabolic process GO:0042402 9 0.014
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.014
cellular component biogenesis GO:0044085 368 0.014
response to corticosterone GO:0051412 40 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
positive regulation of fatty acid beta oxidation GO:0032000 4 0.014
tryptophan catabolic process GO:0006569 5 0.014
positive regulation of molecular function GO:0044093 230 0.014
urea cycle GO:0000050 5 0.014
benzene containing compound metabolic process GO:0042537 22 0.014
positive regulation of coagulation GO:0050820 5 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.013
cellular homeostasis GO:0019725 252 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
response to hypoxia GO:0001666 231 0.013
t cell tolerance induction GO:0002517 3 0.013
catechol containing compound metabolic process GO:0009712 19 0.013
response to chromate GO:0046687 3 0.013
cellular response to dexamethasone stimulus GO:0071549 36 0.013
response to activity GO:0014823 73 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
response to cytokine GO:0034097 215 0.013
response to estradiol GO:0032355 164 0.013
regulation of protein metabolic process GO:0051246 289 0.013
sorbitol biosynthetic process GO:0006061 1 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
single organism cellular localization GO:1902580 102 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
positive regulation of protein metabolic process GO:0051247 178 0.012
sulfur compound biosynthetic process GO:0044272 19 0.012
response to starvation GO:0042594 59 0.012
regulation of fibrinolysis GO:0051917 2 0.012
cardiac chamber development GO:0003205 1 0.012
regulation of angiogenesis GO:0045765 39 0.012
spermatogenesis GO:0007283 99 0.012
nicotinamide nucleotide metabolic process GO:0046496 28 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
regulation of nervous system development GO:0051960 264 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
cellular macromolecule localization GO:0070727 122 0.012
response to vitamin b6 GO:0034516 1 0.012
regulation of protein processing GO:0070613 50 0.012
positive regulation of hemostasis GO:1900048 4 0.012
homeostatic process GO:0042592 331 0.012
oxidoreduction coenzyme metabolic process GO:0006733 31 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
positive regulation of catalytic activity GO:0043085 184 0.011
immune response GO:0006955 104 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
negative regulation of proteolysis GO:0045861 41 0.011
angiogenesis GO:0001525 53 0.011
male gamete generation GO:0048232 99 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
c21 steroid hormone metabolic process GO:0008207 14 0.011
sterol transport GO:0015918 6 0.011
proteolysis GO:0006508 175 0.011
negative regulation of molecular function GO:0044092 133 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
response to fungicide GO:0060992 20 0.011
lipid transport GO:0006869 61 0.011
head development GO:0060322 247 0.011
phosphatidylethanolamine metabolic process GO:0046337 1 0.011
carbohydrate catabolic process GO:0016052 40 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
hepatocyte proliferation GO:0072574 3 0.011
protein transport GO:0015031 132 0.011
regulation of serine type peptidase activity GO:1902571 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
cell activation GO:0001775 97 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
c21 steroid hormone biosynthetic process GO:0006700 10 0.010
catecholamine biosynthetic process GO:0042423 9 0.010
regulation of anatomical structure size GO:0090066 135 0.010
response to vitamin k GO:0032571 4 0.010
regulation of protein modification process GO:0031399 194 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
negative regulation of fibrinolysis GO:0051918 2 0.010
monosaccharide metabolic process GO:0005996 61 0.010
response to dexamethasone GO:0071548 49 0.010
behavior GO:0007610 205 0.010

Otc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.121
cardiovascular system disease DOID:1287 0 0.121
vascular disease DOID:178 0 0.082
disease of metabolism DOID:0014667 0 0.044
inherited metabolic disorder DOID:655 0 0.044
artery disease DOID:0050828 0 0.036
hypertension DOID:10763 0 0.020
essential hypertension DOID:10825 0 0.012