Rattus norvegicus

0 known processes

Mcm2

minichromosome maintenance complex component 2

Mcm2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
histone h3 k9 methylation GO:0051567 1 0.149
dna metabolic process GO:0006259 96 0.119
nucleic acid templated transcription GO:0097659 379 0.109
transcription dna templated GO:0006351 377 0.094
transcription from rna polymerase ii promoter GO:0006366 252 0.093
regulation of nucleic acid templated transcription GO:1903506 380 0.090
positive regulation of multicellular organismal process GO:0051240 387 0.080
tissue development GO:0009888 252 0.068
regulation of transcription dna templated GO:0006355 374 0.067
cellular response to stress GO:0033554 269 0.063
response to molecule of bacterial origin GO:0002237 194 0.063
histone h3 k9 modification GO:0061647 2 0.062
regulation of rna biosynthetic process GO:2001141 381 0.061
pyrimidine nucleobase metabolic process GO:0006206 8 0.059
positive regulation of catalytic activity GO:0043085 184 0.059
response to purine containing compound GO:0014074 126 0.056
nucleoside phosphate metabolic process GO:0006753 283 0.054
single organism biosynthetic process GO:0044711 342 0.054
nucleobase containing small molecule metabolic process GO:0055086 316 0.053
response to estradiol GO:0032355 164 0.052
regulation of programmed cell death GO:0043067 341 0.052
response to ethanol GO:0045471 162 0.052
rna biosynthetic process GO:0032774 380 0.050
anatomical structure morphogenesis GO:0009653 298 0.049
positive regulation of protein metabolic process GO:0051247 178 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.048
tetrahydrofolate metabolic process GO:0046653 9 0.045
rna metabolic process GO:0016070 406 0.042
regulation of cell differentiation GO:0045595 320 0.041
organelle organization GO:0006996 266 0.041
neuron differentiation GO:0030182 368 0.040
regulation of cellular component organization GO:0051128 368 0.038
regulation of rna metabolic process GO:0051252 391 0.038
alpha amino acid metabolic process GO:1901605 71 0.037
regulation of cell proliferation GO:0042127 359 0.037
response to growth factor GO:0070848 189 0.037
single organism reproductive process GO:0044702 297 0.035
macromolecular complex subunit organization GO:0043933 339 0.035
apoptotic process GO:0006915 381 0.034
organophosphate metabolic process GO:0019637 370 0.034
regulation of molecular function GO:0065009 398 0.034
head development GO:0060322 247 0.033
positive regulation of gene expression GO:0010628 244 0.033
nucleobase containing compound catabolic process GO:0034655 152 0.032
protein phosphorylation GO:0006468 345 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
positive regulation of apoptotic process GO:0043065 154 0.032
positive regulation of developmental process GO:0051094 283 0.031
response to metal ion GO:0010038 253 0.030
programmed cell death GO:0012501 392 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
response to alkaloid GO:0043279 132 0.029
regulation of signal transduction GO:0009966 318 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.029
negative regulation of cell communication GO:0010648 158 0.029
response to amino acid GO:0043200 75 0.028
chromosome segregation GO:0007059 2 0.027
response to organophosphorus GO:0046683 102 0.027
double strand break repair GO:0006302 1 0.027
negative regulation of metabolic process GO:0009892 331 0.027
positive regulation of biosynthetic process GO:0009891 319 0.026
response to inorganic substance GO:0010035 377 0.026
response to lipopolysaccharide GO:0032496 191 0.026
rhythmic process GO:0048511 156 0.025
intracellular signal transduction GO:0035556 314 0.025
negative regulation of gene expression GO:0010629 199 0.025
cellular amine metabolic process GO:0044106 38 0.024
cell cycle checkpoint GO:0000075 2 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
positive regulation of molecular function GO:0044093 230 0.022
positive regulation of cell development GO:0010720 176 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
cellular response to platelet derived growth factor stimulus GO:0036120 7 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
eye morphogenesis GO:0048592 4 0.022
positive regulation of cell death GO:0010942 184 0.022
response to ketone GO:1901654 182 0.022
brain development GO:0007420 247 0.022
purine containing compound metabolic process GO:0072521 253 0.021
protein maturation GO:0051604 68 0.021
response to oxygen levels GO:0070482 265 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
regulation of neurogenesis GO:0050767 247 0.021
histone methylation GO:0016571 3 0.020
response to peptide hormone GO:0043434 278 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
response to external biotic stimulus GO:0043207 221 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
positive regulation of cell differentiation GO:0045597 217 0.019
central nervous system development GO:0007417 311 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
response to estrogen GO:0043627 232 0.019
regulation of catalytic activity GO:0050790 304 0.019
chemical homeostasis GO:0048878 292 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
regulation of protein metabolic process GO:0051246 289 0.019
centrosome organization GO:0051297 1 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
chromatin assembly or disassembly GO:0006333 1 0.019
response to bacterium GO:0009617 200 0.019
pyrimidine containing compound metabolic process GO:0072527 20 0.018
pteridine containing compound metabolic process GO:0042558 14 0.018
homeostatic process GO:0042592 331 0.018
aging GO:0007568 241 0.018
regulation of apoptotic process GO:0042981 335 0.018
neuron development GO:0048666 286 0.018
cell proliferation in forebrain GO:0021846 3 0.018
response to decreased oxygen levels GO:0036293 237 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
camera type eye development GO:0043010 48 0.017
circadian rhythm GO:0007623 88 0.017
gamete generation GO:0007276 124 0.017
amine metabolic process GO:0009308 38 0.017
eye development GO:0001654 50 0.017
forebrain development GO:0030900 98 0.017
regulation of nervous system development GO:0051960 264 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
cell cycle GO:0007049 101 0.017
coenzyme metabolic process GO:0006732 86 0.017
regeneration GO:0031099 163 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
cell projection organization GO:0030030 302 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
regulation of protein modification process GO:0031399 194 0.016
organ regeneration GO:0031100 101 0.016
response to other organism GO:0051707 220 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
single organism organelle organization GO:1902589 180 0.016
response to vitamin GO:0033273 131 0.016
protein oligomerization GO:0051259 191 0.016
negative regulation of rna metabolic process GO:0051253 123 0.015
anion transmembrane transport GO:0098656 77 0.015
regulation of cell development GO:0060284 263 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
positive regulation of retinal cell programmed cell death GO:0046670 1 0.015
neuron projection development GO:0031175 273 0.015
dna replication GO:0006260 37 0.015
response to heat GO:0009408 60 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
reproduction GO:0000003 245 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
response to testosterone GO:0033574 55 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
nucleotide metabolic process GO:0009117 279 0.014
sensory organ development GO:0007423 74 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
cellular chemical homeostasis GO:0055082 247 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
male sex differentiation GO:0046661 64 0.014
dna dependent dna replication GO:0006261 5 0.014
ion homeostasis GO:0050801 212 0.014
cellular ketone metabolic process GO:0042180 51 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
reproductive system development GO:0061458 128 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
organ morphogenesis GO:0009887 75 0.013
ras protein signal transduction GO:0007265 29 0.013
response to high density lipoprotein particle GO:0055099 2 0.013
protein complex biogenesis GO:0070271 263 0.013
response to acid chemical GO:0001101 222 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
sexual reproduction GO:0019953 148 0.013
response to cytokine GO:0034097 215 0.013
base excision repair GO:0006284 6 0.013
positive regulation of nervous system development GO:0051962 178 0.012
apoptotic signaling pathway GO:0097190 27 0.012
response to wounding GO:0009611 254 0.012
nucleoside metabolic process GO:0009116 179 0.012
ovulation cycle GO:0042698 67 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
mitotic dna damage checkpoint GO:0044773 1 0.012
response to peptide GO:1901652 292 0.012
positive regulation of signaling GO:0023056 270 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
developmental process involved in reproduction GO:0003006 159 0.012
macromolecule methylation GO:0043414 16 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
response to nutrient levels GO:0031667 370 0.012
cell morphogenesis GO:0000902 142 0.012
organic acid metabolic process GO:0006082 292 0.012
protein localization GO:0008104 191 0.012
positive regulation of organelle organization GO:0010638 48 0.011
protein transport GO:0015031 132 0.011
cognition GO:0050890 92 0.011
cellular cation homeostasis GO:0030003 180 0.011
axis specification GO:0009798 4 0.011
spermatogenesis GO:0007283 99 0.011
cytoplasmic transport GO:0016482 115 0.011
response to extracellular stimulus GO:0009991 380 0.011
multicellular organismal homeostasis GO:0048871 49 0.011
macromolecular complex assembly GO:0065003 273 0.011
cell cycle g1 s phase transition GO:0044843 13 0.011
reproductive structure development GO:0048608 128 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
mitotic cell cycle checkpoint GO:0007093 1 0.011
chromosome organization GO:0051276 36 0.011
palate development GO:0060021 2 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.011
heterocycle catabolic process GO:0046700 167 0.010
mammary gland epithelium development GO:0061180 1 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
camera type eye morphogenesis GO:0048593 2 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
negative regulation of signaling GO:0023057 157 0.010
regulation of cell cycle GO:0051726 73 0.010
sex differentiation GO:0007548 113 0.010
oxoacid metabolic process GO:0043436 290 0.010
activation of cysteine type endopeptidase activity GO:0097202 4 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
positive regulation of lipid catabolic process GO:0050996 4 0.010

Mcm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.039
cancer DOID:162 0 0.039
disease of cellular proliferation DOID:14566 0 0.039
organ system cancer DOID:0050686 0 0.039
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
large intestine cancer DOID:5672 0 0.015
intestinal cancer DOID:10155 0 0.015