Rattus norvegicus

0 known processes

Spry2

sprouty homolog 2 (Drosophila)

Spry2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.146
regulation of transcription dna templated GO:0006355 374 0.112
regulation of rna biosynthetic process GO:2001141 381 0.103
nucleic acid templated transcription GO:0097659 379 0.089
regulation of signal transduction GO:0009966 318 0.075
Human
transcription dna templated GO:0006351 377 0.071
rna biosynthetic process GO:0032774 380 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.065
positive regulation of rna biosynthetic process GO:1902680 197 0.059
rna metabolic process GO:0016070 406 0.059
regulation of rna metabolic process GO:0051252 391 0.056
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.053
positive regulation of rna metabolic process GO:0051254 203 0.053
regulation of multicellular organismal development GO:2000026 376 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.051
positive regulation of cell proliferation GO:0008284 249 0.048
circulatory system development GO:0072359 134 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
central nervous system development GO:0007417 311 0.046
regulation of cell differentiation GO:0045595 320 0.045
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.044
regulation of cell development GO:0060284 263 0.044
transcription from rna polymerase ii promoter GO:0006366 252 0.043
positive regulation of nucleic acid templated transcription GO:1903508 197 0.043
positive regulation of gene expression GO:0010628 244 0.041
Human
regulation of programmed cell death GO:0043067 341 0.040
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
positive regulation of transcription dna templated GO:0045893 197 0.039
negative regulation of gene expression GO:0010629 199 0.039
negative regulation of biosynthetic process GO:0009890 168 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.037
Human
cardiovascular system development GO:0072358 134 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.036
negative regulation of metabolic process GO:0009892 331 0.036
Human
regulation of cellular component organization GO:0051128 368 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
Human
anatomical structure morphogenesis GO:0009653 298 0.034
intracellular signal transduction GO:0035556 314 0.034
Human
head development GO:0060322 247 0.034
response to inorganic substance GO:0010035 377 0.033
neuron development GO:0048666 286 0.031
positive regulation of programmed cell death GO:0043068 157 0.031
regulation of nervous system development GO:0051960 264 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
cell cell signaling GO:0007267 335 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
Human
regulation of molecular function GO:0065009 398 0.031
Human
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.030
cellular response to stress GO:0033554 269 0.030
negative regulation of rna biosynthetic process GO:1902679 118 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.029
homeostatic process GO:0042592 331 0.029
regulation of phosphate metabolic process GO:0019220 349 0.028
Human
regulation of phosphorylation GO:0042325 248 0.028
Human
positive regulation of cellular component organization GO:0051130 200 0.028
brain development GO:0007420 247 0.027
protein phosphorylation GO:0006468 345 0.027
Human
negative regulation of cellular metabolic process GO:0031324 281 0.027
Human
programmed cell death GO:0012501 392 0.027
Human
nitrogen compound transport GO:0071705 229 0.026
response to cytokine GO:0034097 215 0.026
chemical homeostasis GO:0048878 292 0.025
regulation of cell proliferation GO:0042127 359 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
neuron projection development GO:0031175 273 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.024
neuron differentiation GO:0030182 368 0.024
regulation of neurogenesis GO:0050767 247 0.024
locomotion GO:0040011 237 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
Human
response to reactive oxygen species GO:0000302 120 0.024
cellular chemical homeostasis GO:0055082 247 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
Human
metal ion transport GO:0030001 289 0.023
single organism reproductive process GO:0044702 297 0.023
positive regulation of developmental process GO:0051094 283 0.023
regulation of apoptotic process GO:0042981 335 0.023
Human
cellular amino acid metabolic process GO:0006520 107 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
regulation of system process GO:0044057 208 0.023
response to mechanical stimulus GO:0009612 134 0.023
cation transport GO:0006812 382 0.022
organelle organization GO:0006996 266 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
cellular ketone metabolic process GO:0042180 51 0.022
multicellular organism reproduction GO:0032504 233 0.022
cell projection organization GO:0030030 302 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
reproductive process GO:0022414 372 0.021
dephosphorylation GO:0016311 98 0.021
cellular amine metabolic process GO:0044106 38 0.021
transmembrane transport GO:0055085 412 0.021
muscle system process GO:0003012 115 0.021
multi organism reproductive process GO:0044703 262 0.021
mapk cascade GO:0000165 140 0.021
Human
apoptotic process GO:0006915 381 0.021
Human
secretion by cell GO:0032940 248 0.021
proteolysis GO:0006508 175 0.021
response to hydrogen peroxide GO:0042542 89 0.020
smooth muscle cell proliferation GO:0048659 77 0.020
negative regulation of rna metabolic process GO:0051253 123 0.020
secretion GO:0046903 307 0.020
regulation of protein modification process GO:0031399 194 0.020
Human
cell migration GO:0016477 197 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
regulation of cell projection organization GO:0031344 175 0.020
cellular catabolic process GO:0044248 295 0.020
heart morphogenesis GO:0003007 3 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
organic substance catabolic process GO:1901575 316 0.019
anterior posterior pattern specification GO:0009952 1 0.018
organic acid metabolic process GO:0006082 292 0.018
response to oxidative stress GO:0006979 186 0.018
positive regulation of cell communication GO:0010647 271 0.018
Human
positive regulation of cell development GO:0010720 176 0.018
cellular component biogenesis GO:0044085 368 0.018
female pregnancy GO:0007565 122 0.018
negative regulation of developmental process GO:0051093 125 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
response to extracellular stimulus GO:0009991 380 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
circadian rhythm GO:0007623 88 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
response to growth factor GO:0070848 189 0.017
organophosphate metabolic process GO:0019637 370 0.017
catabolic process GO:0009056 351 0.017
negative regulation of cell death GO:0060548 229 0.017
Human
cellular response to growth factor stimulus GO:0071363 162 0.017
cellular homeostasis GO:0019725 252 0.017
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of cell death GO:0010942 184 0.016
metal ion homeostasis GO:0055065 186 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
regulation of stem cell differentiation GO:2000736 2 0.016
chromosome segregation GO:0007059 2 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
regulation of neuron projection development GO:0010975 161 0.016
response to oxygen levels GO:0070482 265 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
Human
response to nutrient levels GO:0031667 370 0.016
negative regulation of neuron differentiation GO:0045665 62 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
ion homeostasis GO:0050801 212 0.015
intracellular transport GO:0046907 185 0.015
oxoacid metabolic process GO:0043436 290 0.015
cation homeostasis GO:0055080 195 0.015
regulation of mapk cascade GO:0043408 116 0.015
Human
ion transmembrane transport GO:0034220 365 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
Human
cell motility GO:0048870 202 0.015
regulation of protein metabolic process GO:0051246 289 0.015
Human
regulation of cellular localization GO:0060341 263 0.015
regulation of cell cycle GO:0051726 73 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
positive regulation of signaling GO:0023056 270 0.015
Human
positive regulation of protein metabolic process GO:0051247 178 0.015
Human
gastrulation GO:0007369 2 0.015
negative regulation of nervous system development GO:0051961 79 0.014
regulation of catalytic activity GO:0050790 304 0.014
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
localization of cell GO:0051674 202 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
Human
inorganic ion transmembrane transport GO:0098660 229 0.014
response to monosaccharide GO:0034284 159 0.014
negative regulation of signaling GO:0023057 157 0.014
response to hypoxia GO:0001666 231 0.014
response to bacterium GO:0009617 200 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
response to glucose GO:0009749 136 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
synaptic transmission GO:0007268 235 0.014
vasculature development GO:0001944 70 0.014
single organism catabolic process GO:0044712 283 0.014
response to hexose GO:0009746 144 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
cellular component movement GO:0006928 248 0.014
cellular response to oxidative stress GO:0034599 76 0.014
gamete generation GO:0007276 124 0.013
reproduction GO:0000003 245 0.013
regulation of synaptic transmission GO:0050804 141 0.013
amine metabolic process GO:0009308 38 0.013
response to radiation GO:0009314 137 0.013
regulation of cell migration GO:0030334 128 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
regulation of muscle system process GO:0090257 79 0.013
vesicle mediated transport GO:0016192 181 0.013
response to decreased oxygen levels GO:0036293 237 0.013
circulatory system process GO:0003013 183 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
single organism biosynthetic process GO:0044711 342 0.013
cytoplasmic transport GO:0016482 115 0.013
protein complex biogenesis GO:0070271 263 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
regulation of neuron differentiation GO:0045664 208 0.013
neuron death GO:0070997 127 0.013
positive regulation of molecular function GO:0044093 230 0.013
Human
positive regulation of nervous system development GO:0051962 178 0.013
regulation of hydrolase activity GO:0051336 143 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
response to metal ion GO:0010038 253 0.013
response to wounding GO:0009611 254 0.013
ras protein signal transduction GO:0007265 29 0.013
regulation of anatomical structure size GO:0090066 135 0.013
cellular component assembly GO:0022607 360 0.013
macromolecular complex assembly GO:0065003 273 0.012
cell cycle GO:0007049 101 0.012
negative regulation of cell communication GO:0010648 158 0.012
protein complex assembly GO:0006461 263 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.012
calcium ion homeostasis GO:0055074 162 0.012
dendrite development GO:0016358 72 0.012
regulation of secretion by cell GO:1903530 208 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
developmental process involved in reproduction GO:0003006 159 0.012
reproductive system development GO:0061458 128 0.012
regulation of membrane potential GO:0042391 110 0.012
muscle cell proliferation GO:0033002 84 0.012
negative regulation of transport GO:0051051 136 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
nucleotide metabolic process GO:0009117 279 0.012
cellular response to external stimulus GO:0071496 118 0.012
salivary gland morphogenesis GO:0007435 1 0.012
salivary gland development GO:0007431 3 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
action potential GO:0001508 54 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
positive regulation of locomotion GO:0040017 102 0.012
response to ketone GO:1901654 182 0.012
gland development GO:0048732 155 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
Human
cell cycle checkpoint GO:0000075 2 0.012
purine containing compound metabolic process GO:0072521 253 0.011
cardiac chamber development GO:0003205 1 0.011
positive regulation of transport GO:0051050 245 0.011
response to lipopolysaccharide GO:0032496 191 0.011
sex differentiation GO:0007548 113 0.011
protein complex subunit organization GO:0071822 302 0.011
axis specification GO:0009798 4 0.011
cellular response to lipid GO:0071396 201 0.011
aging GO:0007568 241 0.011
spindle organization GO:0007051 2 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
neuron apoptotic process GO:0051402 88 0.011
response to insulin GO:0032868 133 0.011
oxidation reduction process GO:0055114 304 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
Human
amide transport GO:0042886 105 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
heterocycle catabolic process GO:0046700 167 0.011
nucleoside metabolic process GO:0009116 179 0.011
response to peptide GO:1901652 292 0.011
regulation of ion transport GO:0043269 245 0.011
regulation of homeostatic process GO:0032844 101 0.011
positive regulation of transcription factor import into nucleus GO:0042993 4 0.011
regulation of dendrite development GO:0050773 59 0.011
cellular ion homeostasis GO:0006873 184 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
lipid metabolic process GO:0006629 283 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
cellular macromolecule localization GO:0070727 122 0.011
negative regulation of molecular function GO:0044092 133 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
behavior GO:0007610 205 0.010
cellular cation homeostasis GO:0030003 180 0.010
male gamete generation GO:0048232 99 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
regulation of neuron death GO:1901214 115 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of protein kinase activity GO:0045859 105 0.010
Human
regulation of synaptic plasticity GO:0048167 70 0.010
single organism behavior GO:0044708 130 0.010
response to estradiol GO:0032355 164 0.010
spermatogenesis GO:0007283 99 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
rhythmic process GO:0048511 156 0.010
regulation of cellular component movement GO:0051270 150 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
growth GO:0040007 165 0.010
response to other organism GO:0051707 220 0.010
gliogenesis GO:0042063 93 0.010
peptidyl amino acid modification GO:0018193 126 0.010
Human

Spry2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.010