Rattus norvegicus

0 known processes

Spry1

sprouty homolog 1, antagonist of FGF signaling (Drosophila)

Spry1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.158
rna metabolic process GO:0016070 406 0.145
regulation of rna metabolic process GO:0051252 391 0.128
rna biosynthetic process GO:0032774 380 0.111
reproduction GO:0000003 245 0.099
negative regulation of cellular metabolic process GO:0031324 281 0.094
negative regulation of metabolic process GO:0009892 331 0.092
regulation of rna biosynthetic process GO:2001141 381 0.088
regulation of nucleic acid templated transcription GO:1903506 380 0.085
nucleic acid templated transcription GO:0097659 379 0.081
intracellular signal transduction GO:0035556 314 0.081
programmed cell death GO:0012501 392 0.073
regulation of molecular function GO:0065009 398 0.070
regulation of intracellular signal transduction GO:1902531 218 0.063
regulation of cellular protein metabolic process GO:0032268 267 0.062
negative regulation of biosynthetic process GO:0009890 168 0.062
negative regulation of gene expression GO:0010629 199 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.061
anatomical structure morphogenesis GO:0009653 298 0.061
organic substance catabolic process GO:1901575 316 0.059
negative regulation of cellular biosynthetic process GO:0031327 161 0.058
transcription dna templated GO:0006351 377 0.058
positive regulation of phosphorus metabolic process GO:0010562 262 0.058
regulation of cell proliferation GO:0042127 359 0.057
response to cytokine GO:0034097 215 0.053
positive regulation of cell communication GO:0010647 271 0.052
positive regulation of multicellular organismal process GO:0051240 387 0.051
positive regulation of cell death GO:0010942 184 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.050
apoptotic process GO:0006915 381 0.050
response to nutrient levels GO:0031667 370 0.049
regulation of protein metabolic process GO:0051246 289 0.049
organic acid metabolic process GO:0006082 292 0.048
regulation of signal transduction GO:0009966 318 0.048
catabolic process GO:0009056 351 0.047
negative regulation of rna biosynthetic process GO:1902679 118 0.047
regulation of catalytic activity GO:0050790 304 0.047
regulation of cellular component organization GO:0051128 368 0.046
cellular response to oxygen containing compound GO:1901701 386 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
multicellular organism reproduction GO:0032504 233 0.044
circulatory system process GO:0003013 183 0.042
regulation of apoptotic process GO:0042981 335 0.041
positive regulation of signaling GO:0023056 270 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
cellular response to endogenous stimulus GO:0071495 377 0.038
small gtpase mediated signal transduction GO:0007264 36 0.038
neuron differentiation GO:0030182 368 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.037
response to molecule of bacterial origin GO:0002237 194 0.037
mapk cascade GO:0000165 140 0.037
cellular response to stress GO:0033554 269 0.037
regulation of programmed cell death GO:0043067 341 0.036
cellular chemical homeostasis GO:0055082 247 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
positive regulation of programmed cell death GO:0043068 157 0.035
response to extracellular stimulus GO:0009991 380 0.035
secretion GO:0046903 307 0.035
cellular component biogenesis GO:0044085 368 0.034
regulation of phosphorylation GO:0042325 248 0.034
cellular response to hormone stimulus GO:0032870 247 0.034
cellular homeostasis GO:0019725 252 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
positive regulation of rna metabolic process GO:0051254 203 0.034
negative regulation of protein metabolic process GO:0051248 114 0.033
cellular response to peptide GO:1901653 133 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
response to peptide GO:1901652 292 0.033
negative regulation of signal transduction GO:0009968 83 0.033
regulation of cellular localization GO:0060341 263 0.033
multi organism reproductive process GO:0044703 262 0.033
cellular amino acid metabolic process GO:0006520 107 0.032
cardiac chamber development GO:0003205 1 0.031
epithelium development GO:0060429 96 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
establishment of tissue polarity GO:0007164 2 0.031
chemical homeostasis GO:0048878 292 0.030
regulation of cell development GO:0060284 263 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
negative regulation of signaling GO:0023057 157 0.030
ras protein signal transduction GO:0007265 29 0.030
cation transport GO:0006812 382 0.030
regulation of cell migration GO:0030334 128 0.030
protein complex assembly GO:0006461 263 0.029
negative regulation of molecular function GO:0044092 133 0.029
response to inorganic substance GO:0010035 377 0.029
positive regulation of gene expression GO:0010628 244 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
response to acid chemical GO:0001101 222 0.029
organophosphate metabolic process GO:0019637 370 0.029
macromolecule localization GO:0033036 252 0.028
macromolecule catabolic process GO:0009057 58 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
reproductive process GO:0022414 372 0.028
single organism intracellular transport GO:1902582 166 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
positive regulation of molecular function GO:0044093 230 0.027
signal transduction by phosphorylation GO:0023014 144 0.027
negative regulation of nucleic acid templated transcription GO:1903507 117 0.027
regulation of proteasomal protein catabolic process GO:0061136 4 0.027
response to peptide hormone GO:0043434 278 0.027
positive regulation of transport GO:0051050 245 0.027
neuron development GO:0048666 286 0.027
proteolysis GO:0006508 175 0.026
neurological system process GO:0050877 219 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
ion homeostasis GO:0050801 212 0.026
glycosyl compound metabolic process GO:1901657 182 0.026
tissue development GO:0009888 252 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
cellular catabolic process GO:0044248 295 0.025
cell projection organization GO:0030030 302 0.025
intracellular transport GO:0046907 185 0.025
nucleobase containing compound catabolic process GO:0034655 152 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
response to decreased oxygen levels GO:0036293 237 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
regulation of system process GO:0044057 208 0.024
establishment of protein localization GO:0045184 141 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
response to bacterium GO:0009617 200 0.024
negative regulation of cellular protein metabolic process GO:0032269 106 0.024
central nervous system development GO:0007417 311 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.023
axis specification GO:0009798 4 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
regulation of ion transport GO:0043269 245 0.023
protein complex subunit organization GO:0071822 302 0.023
ion transmembrane transport GO:0034220 365 0.023
sexual reproduction GO:0019953 148 0.022
cell morphogenesis GO:0000902 142 0.022
intracellular protein transport GO:0006886 79 0.022
response to estrogen GO:0043627 232 0.022
heart morphogenesis GO:0003007 3 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
response to glucocorticoid GO:0051384 223 0.022
negative regulation of transcription dna templated GO:0045892 116 0.022
protein transport GO:0015031 132 0.022
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
cellular amine metabolic process GO:0044106 38 0.021
gastrulation GO:0007369 2 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
vasculature development GO:0001944 70 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of signal transduction GO:0009967 175 0.021
localization of cell GO:0051674 202 0.021
regulation of protein localization GO:0032880 81 0.021
regulation of canonical wnt signaling pathway GO:0060828 4 0.021
response to oxidative stress GO:0006979 186 0.021
negative regulation of transport GO:0051051 136 0.021
response to lipopolysaccharide GO:0032496 191 0.021
single organism catabolic process GO:0044712 283 0.021
regulation of cell differentiation GO:0045595 320 0.021
cardiovascular system development GO:0072358 134 0.021
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of neurogenesis GO:0050767 247 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
protein localization GO:0008104 191 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
single organism reproductive process GO:0044702 297 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
regulation of protein transport GO:0051223 68 0.019
organelle organization GO:0006996 266 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
cell cell signaling GO:0007267 335 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
amine metabolic process GO:0009308 38 0.019
cellular ketone metabolic process GO:0042180 51 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
negative regulation of cell communication GO:0010648 158 0.019
cell cycle GO:0007049 101 0.019
regulation of anatomical structure size GO:0090066 135 0.019
oxidation reduction process GO:0055114 304 0.019
cell type specific apoptotic process GO:0097285 134 0.019
protein phosphorylation GO:0006468 345 0.019
oxoacid metabolic process GO:0043436 290 0.019
regulation of cell projection organization GO:0031344 175 0.019
response to oxygen levels GO:0070482 265 0.019
negative regulation of phosphorus metabolic process GO:0010563 80 0.019
cellular component assembly GO:0022607 360 0.019
cardiac ventricle development GO:0003231 1 0.019
cellular cation homeostasis GO:0030003 180 0.019
secretion by cell GO:0032940 248 0.019
aging GO:0007568 241 0.018
regulation of mapk cascade GO:0043408 116 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
negative regulation of cell death GO:0060548 229 0.018
locomotion GO:0040011 237 0.018
anterior posterior pattern specification GO:0009952 1 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
cellular response to reactive oxygen species GO:0034614 55 0.018
divalent inorganic cation homeostasis GO:0072507 165 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
response to wounding GO:0009611 254 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
regulation of locomotion GO:0040012 148 0.017
bmp signaling pathway GO:0030509 4 0.017
cellular protein localization GO:0034613 122 0.017
single organism organelle organization GO:1902589 180 0.017
blood circulation GO:0008015 183 0.017
muscle system process GO:0003012 115 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
establishment of planar polarity GO:0001736 1 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
cellular ion homeostasis GO:0006873 184 0.017
insulin like growth factor receptor signaling pathway GO:0048009 3 0.017
purine containing compound metabolic process GO:0072521 253 0.017
ribose phosphate metabolic process GO:0019693 235 0.016
metal ion transport GO:0030001 289 0.016
regulation of neuron projection development GO:0010975 161 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
aromatic compound catabolic process GO:0019439 168 0.016
head development GO:0060322 247 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
cell adhesion GO:0007155 110 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
gamete generation GO:0007276 124 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
protein complex biogenesis GO:0070271 263 0.016
signal release GO:0023061 145 0.016
regulation of neuron differentiation GO:0045664 208 0.016
ribonucleotide metabolic process GO:0009259 231 0.015
regulation of secretion GO:0051046 224 0.015
regulation of catabolic process GO:0009894 113 0.015
regulation of hormone levels GO:0010817 187 0.015
growth GO:0040007 165 0.015
heterocycle catabolic process GO:0046700 167 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
response to reactive oxygen species GO:0000302 120 0.015
nucleotide metabolic process GO:0009117 279 0.015
salivary gland development GO:0007431 3 0.015
cytoplasmic transport GO:0016482 115 0.015
cell migration GO:0016477 197 0.015
transmembrane transport GO:0055085 412 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
cellular response to oxidative stress GO:0034599 76 0.015
response to ketone GO:1901654 182 0.015
response to glucose GO:0009749 136 0.015
positive regulation of protein modification process GO:0031401 142 0.015
divalent metal ion transport GO:0070838 132 0.015
cell motility GO:0048870 202 0.015
cellular macromolecule localization GO:0070727 122 0.015
regulation of cellular component movement GO:0051270 150 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
response to carbohydrate GO:0009743 183 0.015
response to corticosteroid GO:0031960 235 0.015
calcium ion homeostasis GO:0055074 162 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
regulation of secretion by cell GO:1903530 208 0.014
regulation of establishment of planar polarity GO:0090175 2 0.014
cellular component movement GO:0006928 248 0.014
actin filament based process GO:0030029 86 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
peptidyl amino acid modification GO:0018193 126 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
regulation of fat cell differentiation GO:0045598 3 0.014
response to hypoxia GO:0001666 231 0.014
regulation of blood vessel size GO:0050880 89 0.014
developmental process involved in reproduction GO:0003006 159 0.014
carboxylic acid transport GO:0046942 115 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
cation homeostasis GO:0055080 195 0.014
renal system development GO:0072001 67 0.014
divalent inorganic cation transport GO:0072511 134 0.014
embryonic pattern specification GO:0009880 1 0.014
organ morphogenesis GO:0009887 75 0.014
regulation of transferase activity GO:0051338 123 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
calcium ion transport GO:0006816 131 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
neuron projection development GO:0031175 273 0.013
positive regulation of developmental process GO:0051094 283 0.013
nitrogen compound transport GO:0071705 229 0.013
response to biotic stimulus GO:0009607 226 0.013
response to growth factor GO:0070848 189 0.013
response to nutrient GO:0007584 248 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
embryonic axis specification GO:0000578 1 0.013
vascular process in circulatory system GO:0003018 96 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
actin cytoskeleton organization GO:0030036 73 0.013
regulation of blood pressure GO:0008217 83 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
response to hexose GO:0009746 144 0.013
heart development GO:0007507 72 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
brain development GO:0007420 247 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
regulation of neuron death GO:1901214 115 0.012
tube development GO:0035295 89 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of nervous system development GO:0051960 264 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
metal ion homeostasis GO:0055065 186 0.012
protein oligomerization GO:0051259 191 0.012
posttranscriptional regulation of gene expression GO:0010608 37 0.012
muscle contraction GO:0006936 88 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
regulation of cell motility GO:2000145 131 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
chromosome segregation GO:0007059 2 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
salivary gland morphogenesis GO:0007435 1 0.012
regulation of cytokine production GO:0001817 56 0.012
positive regulation of nervous system development GO:0051962 178 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
osteoblast differentiation GO:0001649 26 0.012
response to fatty acid GO:0070542 65 0.012
positive regulation of ion transport GO:0043270 94 0.012
regulation of protein kinase activity GO:0045859 105 0.011
regulation of kinase activity GO:0043549 117 0.011
organophosphate catabolic process GO:0046434 148 0.011
single organism biosynthetic process GO:0044711 342 0.011
negative regulation of developmental process GO:0051093 125 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
response to metal ion GO:0010038 253 0.011
muscle structure development GO:0061061 87 0.011
blood vessel morphogenesis GO:0048514 58 0.011
rhythmic process GO:0048511 156 0.011
purine containing compound catabolic process GO:0072523 138 0.011
circulatory system development GO:0072359 134 0.011
neuronal action potential GO:0019228 35 0.011
heart process GO:0003015 57 0.011
cytoskeleton organization GO:0007010 111 0.011
metanephric comma shaped body morphogenesis GO:0072278 2 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of tube size GO:0035150 89 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
regulation of membrane potential GO:0042391 110 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
lipid metabolic process GO:0006629 283 0.011
heart contraction GO:0060047 57 0.011
maintenance of location GO:0051235 17 0.011
regulation of mrna stability GO:0043488 3 0.011
regulation of proteolysis GO:0030162 66 0.011
sex differentiation GO:0007548 113 0.011
cellular response to hydrogen peroxide GO:0070301 42 0.011
anion transport GO:0006820 178 0.011
neuron apoptotic process GO:0051402 88 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
gtp catabolic process GO:0006184 71 0.011
eye morphogenesis GO:0048592 4 0.011
regulation of muscle system process GO:0090257 79 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
vesicle mediated transport GO:0016192 181 0.010
cation transmembrane transport GO:0098655 263 0.010
regulation of metal ion transport GO:0010959 118 0.010
smooth muscle cell migration GO:0014909 36 0.010
regulation of organelle organization GO:0033043 80 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
single organism cellular localization GO:1902580 102 0.010
protein maturation GO:0051604 68 0.010
defense response GO:0006952 194 0.010
taxis GO:0042330 67 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
stress activated protein kinase signaling cascade GO:0031098 37 0.010
dna metabolic process GO:0006259 96 0.010
positive regulation of secretion GO:0051047 140 0.010
rna stabilization GO:0043489 2 0.010
regulation of cell cycle GO:0051726 73 0.010
dephosphorylation GO:0016311 98 0.010
multicellular organism growth GO:0035264 1 0.010

Spry1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
cardiovascular system disease DOID:1287 0 0.015
urinary system disease DOID:18 0 0.014
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.012
disease of cellular proliferation DOID:14566 0 0.010