Rattus norvegicus

0 known processes

Spry4

sprouty homolog 4 (Drosophila)

Spry4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.079
response to nutrient levels GO:0031667 370 0.078
anatomical structure morphogenesis GO:0009653 298 0.071
tissue development GO:0009888 252 0.070
nucleic acid templated transcription GO:0097659 379 0.066
regulation of cell proliferation GO:0042127 359 0.065
negative regulation of metabolic process GO:0009892 331 0.062
rna metabolic process GO:0016070 406 0.060
regulation of programmed cell death GO:0043067 341 0.057
programmed cell death GO:0012501 392 0.055
rna biosynthetic process GO:0032774 380 0.053
apoptotic process GO:0006915 381 0.052
positive regulation of cell proliferation GO:0008284 249 0.049
regulation of apoptotic process GO:0042981 335 0.047
response to inorganic substance GO:0010035 377 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
transcription dna templated GO:0006351 377 0.046
cellular response to stress GO:0033554 269 0.045
regulation of rna biosynthetic process GO:2001141 381 0.045
organic acid metabolic process GO:0006082 292 0.043
intracellular signal transduction GO:0035556 314 0.043
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
regulation of nucleic acid templated transcription GO:1903506 380 0.042
regulation of signal transduction GO:0009966 318 0.042
regulation of cell differentiation GO:0045595 320 0.041
regulation of rna metabolic process GO:0051252 391 0.039
regulation of cell development GO:0060284 263 0.038
regulation of protein metabolic process GO:0051246 289 0.038
brain development GO:0007420 247 0.038
regulation of transcription dna templated GO:0006355 374 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.037
regulation of cell migration GO:0030334 128 0.037
response to ketone GO:1901654 182 0.037
cell migration GO:0016477 197 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.036
positive regulation of signaling GO:0023056 270 0.036
positive regulation of cell communication GO:0010647 271 0.035
neuron differentiation GO:0030182 368 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
regulation of molecular function GO:0065009 398 0.035
cell cell signaling GO:0007267 335 0.034
positive regulation of cellular component movement GO:0051272 102 0.033
response to purine containing compound GO:0014074 126 0.032
response to acid chemical GO:0001101 222 0.032
protein phosphorylation GO:0006468 345 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.031
cation transport GO:0006812 382 0.031
negative regulation of gene expression GO:0010629 199 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
neuron projection development GO:0031175 273 0.030
negative regulation of biosynthetic process GO:0009890 168 0.029
homeostatic process GO:0042592 331 0.029
regulation of catalytic activity GO:0050790 304 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
cellular component biogenesis GO:0044085 368 0.028
regulation of neurogenesis GO:0050767 247 0.028
cellular chemical homeostasis GO:0055082 247 0.028
catabolic process GO:0009056 351 0.028
response to oxygen levels GO:0070482 265 0.027
positive regulation of molecular function GO:0044093 230 0.026
oxoacid metabolic process GO:0043436 290 0.026
cell motility GO:0048870 202 0.026
response to peptide hormone GO:0043434 278 0.026
neurological system process GO:0050877 219 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
response to estradiol GO:0032355 164 0.025
response to organophosphorus GO:0046683 102 0.025
chemical homeostasis GO:0048878 292 0.025
regulation of neuron differentiation GO:0045664 208 0.025
carboxylic acid metabolic process GO:0019752 289 0.024
central nervous system development GO:0007417 311 0.024
response to decreased oxygen levels GO:0036293 237 0.024
locomotion GO:0040011 237 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
positive regulation of developmental process GO:0051094 283 0.024
calcium ion homeostasis GO:0055074 162 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
response to peptide GO:1901652 292 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
cellular catabolic process GO:0044248 295 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
proteolysis GO:0006508 175 0.023
cellular component assembly GO:0022607 360 0.023
head development GO:0060322 247 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
positive regulation of cell death GO:0010942 184 0.022
regulation of cellular component movement GO:0051270 150 0.022
response to estrogen GO:0043627 232 0.022
cellular amine metabolic process GO:0044106 38 0.022
response to amine GO:0014075 46 0.022
metal ion homeostasis GO:0055065 186 0.022
signal release GO:0023061 145 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
regulation of system process GO:0044057 208 0.022
regulation of nervous system development GO:0051960 264 0.021
localization of cell GO:0051674 202 0.021
response to hydrogen peroxide GO:0042542 89 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
negative regulation of cell communication GO:0010648 158 0.021
regulation of neuron projection development GO:0010975 161 0.021
heart morphogenesis GO:0003007 3 0.021
positive regulation of neurogenesis GO:0050769 165 0.020
ras protein signal transduction GO:0007265 29 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
regulation of locomotion GO:0040012 148 0.020
multicellular organism reproduction GO:0032504 233 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
cellular ion homeostasis GO:0006873 184 0.020
cellular homeostasis GO:0019725 252 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
positive regulation of transport GO:0051050 245 0.020
negative regulation of molecular function GO:0044092 133 0.020
response to corticosteroid GO:0031960 235 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
secretion GO:0046903 307 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
synaptic transmission GO:0007268 235 0.019
response to growth factor GO:0070848 189 0.019
regulation of cellular component organization GO:0051128 368 0.019
lipid metabolic process GO:0006629 283 0.019
negative regulation of cell development GO:0010721 82 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
negative regulation of phosphate metabolic process GO:0045936 80 0.018
response to cocaine GO:0042220 39 0.018
cellular ketone metabolic process GO:0042180 51 0.018
regulation of ion transport GO:0043269 245 0.018
ion homeostasis GO:0050801 212 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
regulation of cell projection organization GO:0031344 175 0.018
regulation of canonical wnt signaling pathway GO:0060828 4 0.018
response to reactive oxygen species GO:0000302 120 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
positive regulation of cell development GO:0010720 176 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
response to glucocorticoid GO:0051384 223 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of secretion by cell GO:1903530 208 0.017
organic substance catabolic process GO:1901575 316 0.017
single organism biosynthetic process GO:0044711 342 0.017
hormone secretion GO:0046879 115 0.017
single organism reproductive process GO:0044702 297 0.017
protein complex assembly GO:0006461 263 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
regulation of hormone levels GO:0010817 187 0.017
adult locomotory behavior GO:0008344 4 0.017
single organism catabolic process GO:0044712 283 0.017
rhythmic process GO:0048511 156 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
cellular response to lipid GO:0071396 201 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
cardiovascular system development GO:0072358 134 0.017
response to hypoxia GO:0001666 231 0.017
muscle contraction GO:0006936 88 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
positive regulation of locomotion GO:0040017 102 0.016
reproductive structure development GO:0048608 128 0.016
positive regulation of nervous system development GO:0051962 178 0.016
neuromuscular process GO:0050905 2 0.016
hormone transport GO:0009914 121 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
protein complex subunit organization GO:0071822 302 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
response to metal ion GO:0010038 253 0.016
mapk cascade GO:0000165 140 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
eye morphogenesis GO:0048592 4 0.016
amine metabolic process GO:0009308 38 0.016
regulation of phosphorylation GO:0042325 248 0.016
intracellular transport GO:0046907 185 0.016
reproductive system development GO:0061458 128 0.016
positive regulation of biosynthetic process GO:0009891 319 0.015
aging GO:0007568 241 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
metal ion transport GO:0030001 289 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
insulin like growth factor receptor signaling pathway GO:0048009 3 0.015
reproductive process GO:0022414 372 0.015
positive regulation of gene expression GO:0010628 244 0.015
regulation of cellular localization GO:0060341 263 0.015
neuron development GO:0048666 286 0.015
positive regulation of signal transduction GO:0009967 175 0.015
muscle system process GO:0003012 115 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
cell projection organization GO:0030030 302 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
neuron death GO:0070997 127 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
reproduction GO:0000003 245 0.015
female pregnancy GO:0007565 122 0.014
macromolecular complex assembly GO:0065003 273 0.014
blood circulation GO:0008015 183 0.014
peptide hormone secretion GO:0030072 84 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
dephosphorylation GO:0016311 98 0.014
divalent inorganic cation transport GO:0072511 134 0.014
purine containing compound metabolic process GO:0072521 253 0.014
axis specification GO:0009798 4 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
circadian rhythm GO:0007623 88 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
negative regulation of neuron differentiation GO:0045665 62 0.013
response to glucose GO:0009749 136 0.013
cellular component movement GO:0006928 248 0.013
response to oxidative stress GO:0006979 186 0.013
negative regulation of nervous system development GO:0051961 79 0.013
regulation of protein modification process GO:0031399 194 0.013
regulation of transmembrane transport GO:0034762 122 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
organ morphogenesis GO:0009887 75 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
connective tissue development GO:0061448 33 0.013
response to insulin GO:0032868 133 0.013
small molecule biosynthetic process GO:0044283 124 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
organ formation GO:0048645 3 0.013
response to vitamin GO:0033273 131 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
regulation of cell motility GO:2000145 131 0.013
divalent metal ion transport GO:0070838 132 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
response to wounding GO:0009611 254 0.013
regulation of neurological system process GO:0031644 43 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
multi organism reproductive process GO:0044703 262 0.012
cell morphogenesis GO:0000902 142 0.012
response to mechanical stimulus GO:0009612 134 0.012
positive regulation of cell migration GO:0030335 96 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
circulatory system process GO:0003013 183 0.012
response to camp GO:0051591 91 0.012
transmembrane transport GO:0055085 412 0.012
calcium ion import GO:0070509 22 0.012
positive regulation of cell motility GO:2000147 97 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
cellular cation homeostasis GO:0030003 180 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of metal ion transport GO:0010959 118 0.012
retina morphogenesis in camera type eye GO:0060042 1 0.012
cell cycle GO:0007049 101 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
cation homeostasis GO:0055080 195 0.012
tube development GO:0035295 89 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
bmp signaling pathway GO:0030509 4 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.011
secretion by cell GO:0032940 248 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
learning or memory GO:0007611 90 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
regulation of kinase activity GO:0043549 117 0.011
amide transport GO:0042886 105 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
dna metabolic process GO:0006259 96 0.011
response to nutrient GO:0007584 248 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
anterior posterior pattern specification GO:0009952 1 0.011
tongue morphogenesis GO:0043587 3 0.011
behavior GO:0007610 205 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
response to hexose GO:0009746 144 0.011
negative regulation of signaling GO:0023057 157 0.011
negative regulation of transport GO:0051051 136 0.011
response to monosaccharide GO:0034284 159 0.011
gland development GO:0048732 155 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
positive regulation of protein modification process GO:0031401 142 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
organophosphate metabolic process GO:0019637 370 0.011
response to carbohydrate GO:0009743 183 0.011
mesoderm development GO:0007498 2 0.010
neuron fate commitment GO:0048663 4 0.010
regulation of transporter activity GO:0032409 50 0.010
actin filament based process GO:0030029 86 0.010
negative regulation of protein phosphorylation GO:0001933 44 0.010
defense response GO:0006952 194 0.010
single organism intracellular transport GO:1902582 166 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
regulation of muscle contraction GO:0006937 53 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
positive regulation of ion transport GO:0043270 94 0.010
cellular response to external stimulus GO:0071496 118 0.010
response to radiation GO:0009314 137 0.010
regulation of peptide transport GO:0090087 87 0.010
camera type eye morphogenesis GO:0048593 2 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
regulation of secretion GO:0051046 224 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010

Spry4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020