Rattus norvegicus

0 known processes

Lrrn2

leucine rich repeat neuronal 2

Lrrn2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of metabolic process GO:0009892 331 0.075
regulation of transcription dna templated GO:0006355 374 0.074
negative regulation of macromolecule metabolic process GO:0010605 260 0.074
regulation of nucleic acid templated transcription GO:1903506 380 0.061
inorganic ion transmembrane transport GO:0098660 229 0.057
ion homeostasis GO:0050801 212 0.057
rna biosynthetic process GO:0032774 380 0.055
intracellular signal transduction GO:0035556 314 0.053
rna metabolic process GO:0016070 406 0.052
cation transmembrane transport GO:0098655 263 0.048
homeostatic process GO:0042592 331 0.047
negative regulation of cellular metabolic process GO:0031324 281 0.046
nucleic acid templated transcription GO:0097659 379 0.045
cation transport GO:0006812 382 0.044
regulation of rna metabolic process GO:0051252 391 0.044
regulation of signal transduction GO:0009966 318 0.044
organophosphate metabolic process GO:0019637 370 0.044
transcription dna templated GO:0006351 377 0.043
positive regulation of signal transduction GO:0009967 175 0.042
positive regulation of response to stimulus GO:0048584 285 0.042
cellular ion homeostasis GO:0006873 184 0.041
metal ion homeostasis GO:0055065 186 0.041
regulation of rna biosynthetic process GO:2001141 381 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
positive regulation of signaling GO:0023056 270 0.038
multi organism reproductive process GO:0044703 262 0.037
protein phosphorylation GO:0006468 345 0.037
Rat
cardiovascular system development GO:0072358 134 0.037
cellular component biogenesis GO:0044085 368 0.037
inorganic cation transmembrane transport GO:0098662 202 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
cellular cation homeostasis GO:0030003 180 0.035
divalent metal ion transport GO:0070838 132 0.034
monovalent inorganic cation transport GO:0015672 172 0.034
growth GO:0040007 165 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.033
hormone secretion GO:0046879 115 0.033
cell cell signaling GO:0007267 335 0.032
aging GO:0007568 241 0.032
regulation of cellular component organization GO:0051128 368 0.031
regulation of ion transport GO:0043269 245 0.031
neuron projection development GO:0031175 273 0.031
regulation of protein metabolic process GO:0051246 289 0.030
Rat
divalent inorganic cation transport GO:0072511 134 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
negative regulation of developmental process GO:0051093 125 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
Rat
cation homeostasis GO:0055080 195 0.029
ion transmembrane transport GO:0034220 365 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
reproductive process GO:0022414 372 0.029
defense response GO:0006952 194 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
positive regulation of gene expression GO:0010628 244 0.028
blood circulation GO:0008015 183 0.028
synaptic transmission GO:0007268 235 0.028
regulation of apoptotic process GO:0042981 335 0.027
response to inorganic substance GO:0010035 377 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
regulation of peptide secretion GO:0002791 82 0.027
central nervous system development GO:0007417 311 0.027
catabolic process GO:0009056 351 0.027
cellular component movement GO:0006928 248 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
positive regulation of protein metabolic process GO:0051247 178 0.026
Rat
regulation of secretion GO:0051046 224 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
Rat
regulation of membrane potential GO:0042391 110 0.025
cellular chemical homeostasis GO:0055082 247 0.025
transmembrane transport GO:0055085 412 0.025
regulation of peptide hormone secretion GO:0090276 80 0.025
regulation of hormone secretion GO:0046883 106 0.025
regulation of cellular localization GO:0060341 263 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
macromolecular complex subunit organization GO:0043933 339 0.024
negative regulation of signaling GO:0023057 157 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
cellular divalent inorganic cation homeostasis GO:0072503 162 0.024
cellular component assembly GO:0022607 360 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
organic acid metabolic process GO:0006082 292 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
oxoacid metabolic process GO:0043436 290 0.023
chemical homeostasis GO:0048878 292 0.022
signal release GO:0023061 145 0.022
positive regulation of cell communication GO:0010647 271 0.022
regulation of secretion by cell GO:1903530 208 0.022
sensory perception GO:0007600 101 0.022
regulation of metal ion transport GO:0010959 118 0.022
single organism intracellular transport GO:1902582 166 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
positive regulation of protein modification process GO:0031401 142 0.022
Rat
glycosyl compound metabolic process GO:1901657 182 0.021
neuron differentiation GO:0030182 368 0.021
locomotion GO:0040011 237 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
multicellular organism growth GO:0035264 1 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
positive regulation of molecular function GO:0044093 230 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
head development GO:0060322 247 0.021
peptide secretion GO:0002790 86 0.021
regulation of calcium ion transport GO:0051924 77 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
negative regulation of transcription dna templated GO:0045892 116 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
cytosolic calcium ion homeostasis GO:0051480 140 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
transmission of nerve impulse GO:0019226 42 0.020
single organism biosynthetic process GO:0044711 342 0.020
protein complex assembly GO:0006461 263 0.019
cellular homeostasis GO:0019725 252 0.019
nitrogen compound transport GO:0071705 229 0.019
regulation of programmed cell death GO:0043067 341 0.019
response to metal ion GO:0010038 253 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
positive regulation of transcription dna templated GO:0045893 197 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
response to cytokine GO:0034097 215 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
nucleotide metabolic process GO:0009117 279 0.018
dephosphorylation GO:0016311 98 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
positive regulation of developmental process GO:0051094 283 0.018
negative regulation of rna metabolic process GO:0051253 123 0.018
hormone transport GO:0009914 121 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
single organism membrane organization GO:0044802 74 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
regulation of peptide transport GO:0090087 87 0.017
peptidyl amino acid modification GO:0018193 126 0.017
cellular catabolic process GO:0044248 295 0.017
secretion GO:0046903 307 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
Rat
regulation of neurogenesis GO:0050767 247 0.017
developmental growth GO:0048589 100 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
circulatory system development GO:0072359 134 0.017
camp metabolic process GO:0046058 63 0.017
cellular amine metabolic process GO:0044106 38 0.017
membrane organization GO:0061024 94 0.017
heart morphogenesis GO:0003007 3 0.017
purine nucleotide metabolic process GO:0006163 229 0.016
regulation of protein modification process GO:0031399 194 0.016
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.016
Rat
metal ion transport GO:0030001 289 0.016
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
negative regulation of secretion by cell GO:1903531 72 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
Rat
cell morphogenesis GO:0000902 142 0.016
ras protein signal transduction GO:0007265 29 0.016
sexual reproduction GO:0019953 148 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
negative regulation of molecular function GO:0044092 133 0.016
response to alkaloid GO:0043279 132 0.016
membrane depolarization during action potential GO:0086010 1 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
response to extracellular stimulus GO:0009991 380 0.015
neurological system process GO:0050877 219 0.015
regulation of response to stress GO:0080134 126 0.015
negative regulation of cell death GO:0060548 229 0.015
cell projection organization GO:0030030 302 0.015
macromolecular complex assembly GO:0065003 273 0.015
regulation of catalytic activity GO:0050790 304 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
Rat
regulation of neuron projection development GO:0010975 161 0.015
gamete generation GO:0007276 124 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
amine metabolic process GO:0009308 38 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
multicellular organismal signaling GO:0035637 44 0.015
reproduction GO:0000003 245 0.015
negative regulation of gene expression GO:0010629 199 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
brain development GO:0007420 247 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of molecular function GO:0065009 398 0.014
protein oligomerization GO:0051259 191 0.014
multicellular organism reproduction GO:0032504 233 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
cellular ketone metabolic process GO:0042180 51 0.014
maintenance of location GO:0051235 17 0.014
peptide hormone secretion GO:0030072 84 0.014
second messenger mediated signaling GO:0019932 51 0.014
programmed cell death GO:0012501 392 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
negative regulation of cell communication GO:0010648 158 0.014
macromolecule localization GO:0033036 252 0.014
regulation of insulin secretion GO:0050796 65 0.013
single organism organelle organization GO:1902589 180 0.013
organelle organization GO:0006996 266 0.013
apoptotic process GO:0006915 381 0.013
negative regulation of cell development GO:0010721 82 0.013
response to nutrient levels GO:0031667 370 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
Rat
regulation of neuron death GO:1901214 115 0.013
aromatic compound catabolic process GO:0019439 168 0.013
regulation of cell projection organization GO:0031344 175 0.013
response to bacterium GO:0009617 200 0.013
regulation of cell differentiation GO:0045595 320 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
cell motility GO:0048870 202 0.013
organ morphogenesis GO:0009887 75 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
negative regulation of secretion GO:0051048 82 0.013
regulation of protein localization GO:0032880 81 0.013
response to wounding GO:0009611 254 0.013
response to hexose GO:0009746 144 0.013
neuron death GO:0070997 127 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
regulation of kinase activity GO:0043549 117 0.012
purine containing compound metabolic process GO:0072521 253 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
peptide transport GO:0015833 97 0.012
response to oxidative stress GO:0006979 186 0.012
inflammatory response GO:0006954 150 0.012
protein localization GO:0008104 191 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
regulation of hormone levels GO:0010817 187 0.012
regulation of system process GO:0044057 208 0.012
circulatory system process GO:0003013 183 0.012
spindle organization GO:0007051 2 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
response to ethanol GO:0045471 162 0.012
intracellular transport GO:0046907 185 0.012
cell adhesion GO:0007155 110 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
single organism reproductive process GO:0044702 297 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of phosphorylation GO:0042325 248 0.011
Rat
immune system process GO:0002376 204 0.011
calcium ion transport GO:0006816 131 0.011
eye morphogenesis GO:0048592 4 0.011
protein complex biogenesis GO:0070271 263 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
protein autophosphorylation GO:0046777 66 0.011
neuronal action potential GO:0019228 35 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
cellular response to stress GO:0033554 269 0.011
regulation of nervous system development GO:0051960 264 0.011
mapk cascade GO:0000165 140 0.011
sequestering of metal ion GO:0051238 9 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
single organism catabolic process GO:0044712 283 0.011
regulation of catabolic process GO:0009894 113 0.011
cell type specific apoptotic process GO:0097285 134 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
regulation of axonogenesis GO:0050770 37 0.011
regulation of homeostatic process GO:0032844 101 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
cell projection morphogenesis GO:0048858 123 0.011
axon development GO:0061564 96 0.010
actin filament based process GO:0030029 86 0.010
sodium ion transmembrane transport GO:0035725 67 0.010
regulation of growth GO:0040008 105 0.010
regulation of mapk cascade GO:0043408 116 0.010
regulation of transferase activity GO:0051338 123 0.010
dna integrity checkpoint GO:0031570 2 0.010
cell migration GO:0016477 197 0.010
negative regulation of neuron apoptotic process GO:0043524 45 0.010
neuron development GO:0048666 286 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
response to growth factor GO:0070848 189 0.010
protein complex subunit organization GO:0071822 302 0.010
negative regulation of nervous system development GO:0051961 79 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
regulation of neuron differentiation GO:0045664 208 0.010

Lrrn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
central nervous system disease DOID:331 0 0.012