Rattus norvegicus

0 known processes

Hsph1

heat shock 105/110 protein 1

(Aliases: Hsp105)

Hsph1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein refolding GO:0042026 3 1.000
Yeast
chaperone mediated protein folding GO:0061077 6 0.998
Mouse
de novo posttranslational protein folding GO:0051084 2 0.994
Mouse
positive regulation of protein binding GO:0032092 9 0.993
Rat
protein folding GO:0006457 12 0.991
Yeast Mouse Rat
positive regulation of protein import into nucleus translocation GO:0033160 7 0.987
chlorinated hydrocarbon metabolic process GO:0042196 4 0.980
de novo protein folding GO:0006458 2 0.979
Mouse
protein transmembrane transport GO:0071806 2 0.929
transmembrane transport GO:0055085 412 0.907
response to topologically incorrect protein GO:0035966 8 0.893
Rat
establishment of protein localization to organelle GO:0072594 44 0.888
response to heat GO:0009408 60 0.883
Rat
regulation of cardiac muscle contraction GO:0055117 17 0.878
positive regulation of intracellular protein transport GO:0090316 20 0.866
chaperone mediated protein folding requiring cofactor GO:0051085 2 0.842
Mouse
response to unfolded protein GO:0006986 6 0.839
Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.825
Yeast
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.799
protein targeting GO:0006605 61 0.797
positive regulation of protein import into nucleus GO:0042307 14 0.768
protein transport GO:0015031 132 0.755
regulation of molecular function GO:0065009 398 0.752
Yeast Rat
er associated ubiquitin dependent protein catabolic process GO:0030433 1 0.715
establishment of protein localization GO:0045184 141 0.692
regulation of lymphocyte mediated immunity GO:0002706 11 0.688
mitochondrion organization GO:0007005 35 0.674
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.669
intracellular protein transport GO:0006886 79 0.668
detection of stimulus GO:0051606 24 0.648
regulation of protein metabolic process GO:0051246 289 0.637
Rat
positive regulation of cardiac muscle contraction GO:0060452 4 0.631
regulation of protein modification process GO:0031399 194 0.631
Rat
single organism cellular localization GO:1902580 102 0.600
programmed cell death GO:0012501 392 0.588
Rat
macromolecule localization GO:0033036 252 0.560
regulation of cellular protein metabolic process GO:0032268 267 0.547
Rat
nucleoside monophosphate catabolic process GO:0009125 56 0.531
Yeast
regulation of catalytic activity GO:0050790 304 0.518
Yeast
protein import into nucleus translocation GO:0000060 9 0.504
protein import GO:0017038 37 0.485
single organism intracellular transport GO:1902582 166 0.466
regulation of hydrolase activity GO:0051336 143 0.464
cellular response to topologically incorrect protein GO:0035967 3 0.461
purine nucleoside monophosphate metabolic process GO:0009126 84 0.452
Yeast
cellular protein localization GO:0034613 122 0.449
regulation of programmed cell death GO:0043067 341 0.446
Rat
xenobiotic metabolic process GO:0006805 19 0.420
proteolysis GO:0006508 175 0.405
protein localization GO:0008104 191 0.404
intracellular transport GO:0046907 185 0.393
regulation of adaptive immune response GO:0002819 8 0.388
cell killing GO:0001906 13 0.385
negative regulation of apoptotic process GO:0043066 181 0.384
Rat
cellular macromolecule localization GO:0070727 122 0.369
single organism catabolic process GO:0044712 283 0.337
Yeast
isotype switching to igg isotypes GO:0048291 1 0.335
positive regulation of striated muscle contraction GO:0045989 5 0.334
nucleoside monophosphate metabolic process GO:0009123 93 0.332
Yeast
positive regulation of cell size GO:0045793 8 0.323
neuron recognition GO:0008038 9 0.323
protein localization to organelle GO:0033365 57 0.323
neurotransmitter secretion GO:0007269 33 0.322
regulation of cell development GO:0060284 263 0.321
axon guidance GO:0007411 24 0.321
positive regulation of muscle contraction GO:0045933 22 0.316
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.312
Yeast
circulatory system process GO:0003013 183 0.308
regulation of blood circulation GO:1903522 110 0.303
regulation of system process GO:0044057 208 0.298
protein localization to mitochondrion GO:0070585 7 0.284
cellular component movement GO:0006928 248 0.275
regulation of protein import into nucleus GO:0042306 24 0.274
negative regulation of neuron apoptotic process GO:0043524 45 0.268
atp metabolic process GO:0046034 72 0.267
Yeast
striated muscle contraction GO:0006941 44 0.259
regulation of protein targeting GO:1903533 28 0.256
mitochondrial transport GO:0006839 19 0.255
musculoskeletal movement GO:0050881 17 0.252
t cell mediated cytotoxicity GO:0001913 5 0.251
response to temperature stimulus GO:0009266 94 0.248
Rat
cellular response to xenobiotic stimulus GO:0071466 19 0.248
purine ribonucleotide catabolic process GO:0009154 136 0.244
Yeast
regulation of phosphate metabolic process GO:0019220 349 0.239
Rat
multicellular organismal movement GO:0050879 17 0.238
myosin filament organization GO:0031033 2 0.230
regulation of t cell mediated immunity GO:0002709 6 0.228
cytoplasmic transport GO:0016482 115 0.226
cellular component biogenesis GO:0044085 368 0.225
b cell mediated immunity GO:0019724 4 0.222
somatic cell dna recombination GO:0016444 2 0.217
regulation of cellular component organization GO:0051128 368 0.216
organelle organization GO:0006996 266 0.214
negative regulation of cell death GO:0060548 229 0.203
Rat
regulation of cell killing GO:0031341 12 0.203
negative regulation of programmed cell death GO:0043069 183 0.202
Rat
cellular catabolic process GO:0044248 295 0.201
Yeast
locomotion GO:0040011 237 0.196
regulation of lamellipodium organization GO:1902743 5 0.190
blood circulation GO:0008015 183 0.185
lymphocyte mediated immunity GO:0002449 14 0.181
dna damage response detection of dna damage GO:0042769 2 0.179
toxin transport GO:1901998 3 0.177
microtubule organizing center organization GO:0031023 1 0.175
neuron apoptotic process GO:0051402 88 0.170
positive regulation of leukocyte mediated immunity GO:0002705 13 0.167
positive regulation of lymphocyte mediated immunity GO:0002708 7 0.167
negative regulation of cellular component organization GO:0051129 83 0.166
negative regulation of metabolic process GO:0009892 331 0.165
Rat
single organism nuclear import GO:1902593 35 0.162
positive regulation of cell killing GO:0031343 9 0.161
purine containing compound metabolic process GO:0072521 253 0.158
Yeast
response to tumor cell GO:0002347 4 0.158
regulation of protein serine threonine kinase activity GO:0071900 64 0.156
regulation of protein phosphorylation GO:0001932 183 0.155
Rat
response to xenobiotic stimulus GO:0009410 23 0.151
regulation of kinase activity GO:0043549 117 0.148
regulation of neuron differentiation GO:0045664 208 0.146
regulation of immune response GO:0050776 55 0.146
establishment of protein localization to membrane GO:0090150 16 0.144
regulation of striated muscle contraction GO:0006942 21 0.143
regulation of homeostatic process GO:0032844 101 0.143
vascular process in circulatory system GO:0003018 96 0.143
regulation of jun kinase activity GO:0043506 10 0.141
muscle system process GO:0003012 115 0.139
t cell mediated immunity GO:0002456 7 0.139
negative regulation of molecular function GO:0044092 133 0.137
Rat
protein phosphorylation GO:0006468 345 0.136
Rat
regulation of phosphorylation GO:0042325 248 0.134
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.134
Rat
positive regulation of protein modification process GO:0031401 142 0.133
apoptotic process GO:0006915 381 0.131
Rat
negative regulation of protein metabolic process GO:0051248 114 0.130
Rat
response to atp GO:0033198 13 0.125
purine ribonucleoside metabolic process GO:0046128 168 0.124
Yeast
regulation of phosphorus metabolic process GO:0051174 349 0.123
Rat
cell type specific apoptotic process GO:0097285 134 0.122
nucleocytoplasmic transport GO:0006913 48 0.121
protein localization to membrane GO:0072657 36 0.120
positive regulation of heart contraction GO:0045823 15 0.119
blood vessel development GO:0001568 69 0.119
Rat
carbohydrate derivative catabolic process GO:1901136 147 0.117
Yeast
organic substance catabolic process GO:1901575 316 0.117
Yeast
regulation of anatomical structure size GO:0090066 135 0.116
positive regulation of phosphate metabolic process GO:0045937 262 0.116
regulation of signal transduction GO:0009966 318 0.114
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.114
leukocyte mediated immunity GO:0002443 28 0.113
nucleoside triphosphate metabolic process GO:0009141 144 0.113
Yeast
regulation of jnk cascade GO:0046328 19 0.111
positive regulation of immune system process GO:0002684 90 0.111
muscle cell apoptotic process GO:0010657 30 0.109
dna replication GO:0006260 37 0.109
positive regulation of immune response GO:0050778 42 0.109
cardiac muscle contraction GO:0060048 27 0.105
regulation of nucleic acid templated transcription GO:1903506 380 0.103
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 6 0.103
positive regulation of transport GO:0051050 245 0.101
positive regulation of lamellipodium assembly GO:0010592 4 0.101
cell motility GO:0048870 202 0.101
regulation of interleukin 12 production GO:0032655 3 0.100
regulation of protein transport GO:0051223 68 0.099
response to salt stress GO:0009651 21 0.096
localization of cell GO:0051674 202 0.096
regulation of cellular localization GO:0060341 263 0.095
protein targeting to membrane GO:0006612 11 0.094
cellular macromolecule catabolic process GO:0044265 29 0.094
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.093
defense response GO:0006952 194 0.093
skeletal muscle contraction GO:0003009 17 0.092
regulation of muscle contraction GO:0006937 53 0.092
modification dependent macromolecule catabolic process GO:0043632 14 0.091
regulation of immune response to tumor cell GO:0002837 3 0.090
positive regulation of atpase activity GO:0032781 6 0.090
regulation of protein processing GO:0070613 50 0.089
protein catabolic process GO:0030163 30 0.089
cellular component assembly GO:0022607 360 0.087
glycosyl compound metabolic process GO:1901657 182 0.087
Yeast
positive regulation of programmed cell death GO:0043068 157 0.084
regulation of response to tumor cell GO:0002834 3 0.084
leukocyte mediated cytotoxicity GO:0001909 10 0.084
regulation of apoptotic process GO:0042981 335 0.083
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.083
regulation of tube size GO:0035150 89 0.083
nucleoside phosphate metabolic process GO:0006753 283 0.083
Yeast
positive regulation of phosphorus metabolic process GO:0010562 262 0.082
positive regulation of gene expression GO:0010628 244 0.081
Rat
response to estrogen GO:0043627 232 0.080
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.080
regulation of map kinase activity GO:0043405 53 0.080
vasoconstriction GO:0042310 54 0.080
response to purine containing compound GO:0014074 126 0.079
cellular component morphogenesis GO:0032989 155 0.078
regulation of establishment of protein localization GO:0070201 69 0.078
regulation of multicellular organismal development GO:2000026 376 0.078
Rat
protein modification by small protein conjugation GO:0032446 31 0.077
protein targeting to mitochondrion GO:0006626 7 0.076
actin filament organization GO:0007015 42 0.075
cellular response to stress GO:0033554 269 0.073
rna biosynthetic process GO:0032774 380 0.073
signal release GO:0023061 145 0.071
catabolic process GO:0009056 351 0.070
Yeast
positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 0.070
regulation of cell size GO:0008361 37 0.070
regulation of leukocyte mediated immunity GO:0002703 19 0.067
heart process GO:0003015 57 0.066
negative regulation of protein phosphorylation GO:0001933 44 0.066
Rat
protein import into nucleus GO:0006606 35 0.066
positive regulation of developmental process GO:0051094 283 0.066
Rat
single organism biosynthetic process GO:0044711 342 0.065
cellular response to cytokine stimulus GO:0071345 127 0.065
regulation of immune system process GO:0002682 123 0.065
regulation of transferase activity GO:0051338 123 0.065
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 8 0.065
membrane organization GO:0061024 94 0.064
positive regulation of protein phosphorylation GO:0001934 135 0.064
b cell activation involved in immune response GO:0002312 1 0.064
regulation of protein kinase activity GO:0045859 105 0.063
regulation of myeloid cell apoptotic process GO:0033032 6 0.063
response to osmotic stress GO:0006970 42 0.062
cellular response to organic cyclic compound GO:0071407 202 0.061
positive regulation of protein localization to nucleus GO:1900182 15 0.060
single organism organelle organization GO:1902589 180 0.060
centrosome organization GO:0051297 1 0.060
purine nucleoside monophosphate catabolic process GO:0009128 55 0.059
Yeast
atp catabolic process GO:0006200 54 0.059
Yeast
macromolecular complex subunit organization GO:0043933 339 0.058
regulation of cell differentiation GO:0045595 320 0.058
protein complex subunit organization GO:0071822 302 0.057
negative regulation of stress activated mapk cascade GO:0032873 4 0.057
regulation of leukocyte mediated cytotoxicity GO:0001910 10 0.057
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.056
carbohydrate derivative metabolic process GO:1901135 346 0.056
Yeast
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.055
positive regulation of t cell mediated immunity GO:0002711 4 0.055
reproductive process GO:0022414 372 0.055
macromolecular complex assembly GO:0065003 273 0.054
secretion GO:0046903 307 0.053
positive regulation of catalytic activity GO:0043085 184 0.053
regulation of peptidase activity GO:0052547 55 0.053
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.053
ribonucleoside monophosphate catabolic process GO:0009158 55 0.053
Yeast
regulation of response to stress GO:0080134 126 0.053
axonal fasciculation GO:0007413 5 0.051
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 17 0.051
positive regulation of protein transport GO:0051222 41 0.051
purine nucleoside metabolic process GO:0042278 169 0.051
Yeast
regulation of chromosome organization GO:0033044 9 0.051
cell migration GO:0016477 197 0.050
positive regulation of cellular protein metabolic process GO:0032270 167 0.050
positive regulation of molecular function GO:0044093 230 0.050
Rat
cellular response to unfolded protein GO:0034620 2 0.048
immune system process GO:0002376 204 0.048
positive regulation of transferase activity GO:0051347 81 0.048
cellular protein catabolic process GO:0044257 19 0.048
positive regulation of interferon gamma production GO:0032729 2 0.048
positive regulation of cell differentiation GO:0045597 217 0.047
ribonucleoside metabolic process GO:0009119 174 0.047
Yeast
cardiovascular system development GO:0072358 134 0.047
Rat
regulation of muscle system process GO:0090257 79 0.047
response to mechanical stimulus GO:0009612 134 0.046
cellular response to heat GO:0034605 9 0.046
neuron projection guidance GO:0097485 24 0.046
regulation of cell projection organization GO:0031344 175 0.046
muscle contraction GO:0006936 88 0.045
negative regulation of cellular protein metabolic process GO:0032269 106 0.045
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.045
nuclear import GO:0051170 35 0.045
signal transduction by phosphorylation GO:0023014 144 0.045
ribonucleoside triphosphate catabolic process GO:0009203 122 0.045
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.045
Yeast
nuclear transport GO:0051169 49 0.044
ribonucleoside monophosphate metabolic process GO:0009161 88 0.044
Yeast
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
Rat
regulation of cysteine type endopeptidase activity GO:2000116 32 0.044
intracellular signal transduction GO:0035556 314 0.044
negative regulation of phosphorus metabolic process GO:0010563 80 0.044
Rat
regulation of neurogenesis GO:0050767 247 0.043
positive regulation of homeostatic process GO:0032846 49 0.043
positive regulation of immune effector process GO:0002699 19 0.043
vesicle mediated transport GO:0016192 181 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.043
protein complex assembly GO:0006461 263 0.042
heterocycle catabolic process GO:0046700 167 0.042
Yeast
secretion by cell GO:0032940 248 0.042
regulation of reactive oxygen species metabolic process GO:2000377 26 0.042
positive regulation of cellular component biogenesis GO:0044089 55 0.041
ribonucleoside catabolic process GO:0042454 126 0.041
Yeast
neuron death GO:0070997 127 0.040
regulation of proteolysis GO:0030162 66 0.040
negative regulation of gene expression GO:0010629 199 0.040
Rat
cell cell signaling GO:0007267 335 0.040
organophosphate catabolic process GO:0046434 148 0.039
Yeast
protein ubiquitination GO:0016567 28 0.038
oxidation reduction process GO:0055114 304 0.038
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.038
regulation of protein import into nucleus translocation GO:0033158 8 0.038
spindle organization GO:0007051 2 0.037
regulation of protein localization GO:0032880 81 0.037
nucleoside phosphate catabolic process GO:1901292 140 0.037
Yeast
posttranscriptional gene silencing GO:0016441 1 0.037
regulation of nervous system development GO:0051960 264 0.037
negative regulation of jnk cascade GO:0046329 4 0.036
rna stabilization GO:0043489 2 0.036
reactive oxygen species metabolic process GO:0072593 37 0.036
protein complex biogenesis GO:0070271 263 0.036
regulation of atpase activity GO:0043462 7 0.036
regulation of cellular component biogenesis GO:0044087 86 0.035
cerebellar purkinje cell layer development GO:0021680 2 0.035
regulation of protein localization to nucleus GO:1900180 25 0.035
positive regulation of protein metabolic process GO:0051247 178 0.035
positive regulation of nervous system development GO:0051962 178 0.035
positive regulation of phosphorylation GO:0042327 177 0.035
ribonucleotide catabolic process GO:0009261 136 0.035
Yeast
neurotransmitter transport GO:0006836 42 0.034
regulation of protein maturation GO:1903317 50 0.034
organic acid biosynthetic process GO:0016053 83 0.034
reactive oxygen species biosynthetic process GO:1903409 8 0.033
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.033
regulation of blood vessel size GO:0050880 89 0.033
positive regulation of cell death GO:0010942 184 0.032
positive regulation of blood circulation GO:1903524 65 0.032
regulation of neuron death GO:1901214 115 0.032
taxis GO:0042330 67 0.031
positive regulation of kinase activity GO:0033674 77 0.031
lymphocyte proliferation GO:0046651 29 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
Yeast
ribonucleotide metabolic process GO:0009259 231 0.031
Yeast
regulation of organelle organization GO:0033043 80 0.031
somatic diversification of immune receptors GO:0002200 2 0.030
reproduction GO:0000003 245 0.030
dna metabolic process GO:0006259 96 0.029
somatic recombination of immunoglobulin gene segments GO:0016447 1 0.029
ribonucleoprotein complex subunit organization GO:0071826 8 0.029
nucleic acid templated transcription GO:0097659 379 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
Rat
regulation of transcription dna templated GO:0006355 374 0.029
striated muscle cell development GO:0055002 26 0.029
positive regulation of neuron differentiation GO:0045666 126 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
regulation of cellular response to stress GO:0080135 49 0.028
chromosome organization GO:0051276 36 0.028
cell morphogenesis involved in differentiation GO:0000904 119 0.028
positive regulation of protein kinase activity GO:0045860 73 0.028
neuron migration GO:0001764 21 0.028
response to ethanol GO:0045471 162 0.028
cell activation GO:0001775 97 0.028
regulation of response to external stimulus GO:0032101 106 0.028
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.028
negative regulation of peptidase activity GO:0010466 38 0.028
organonitrogen compound catabolic process GO:1901565 179 0.028
Yeast
immunoglobulin mediated immune response GO:0016064 4 0.028
intracellular receptor signaling pathway GO:0030522 35 0.027
myeloid cell apoptotic process GO:0033028 6 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
cell projection organization GO:0030030 302 0.027
regulation of immune effector process GO:0002697 32 0.027
adaptive immune response GO:0002250 14 0.027
response to radiation GO:0009314 137 0.027
organophosphate metabolic process GO:0019637 370 0.027
Yeast
regulation of endopeptidase activity GO:0052548 51 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
Yeast
positive regulation of apoptotic process GO:0043065 154 0.027
positive regulation of cytoplasmic transport GO:1903651 32 0.026
interleukin 12 production GO:0032615 3 0.026
glycosyl compound catabolic process GO:1901658 126 0.026
Yeast
positive regulation of cell development GO:0010720 176 0.026
negative regulation of catalytic activity GO:0043086 103 0.026
icosanoid metabolic process GO:0006690 38 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
regulation of heart contraction GO:0008016 48 0.026
immune response GO:0006955 104 0.025
histamine secretion by mast cell GO:0002553 3 0.025
regulation of nucleocytoplasmic transport GO:0046822 28 0.025
response to hypoxia GO:0001666 231 0.025
ribonucleoside triphosphate metabolic process GO:0009199 141 0.025
Yeast
nucleoside metabolic process GO:0009116 179 0.025
Yeast
regulation of retinal cell programmed cell death GO:0046668 1 0.024
protein oligomerization GO:0051259 191 0.024
regulation of interferon gamma production GO:0032649 3 0.024
nucleotide metabolic process GO:0009117 279 0.024
Yeast
establishment of protein localization to mitochondrion GO:0072655 7 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
posttranscriptional regulation of gene expression GO:0010608 37 0.024
response to decreased oxygen levels GO:0036293 237 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.023
Yeast
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 1 0.023
response to organophosphorus GO:0046683 102 0.023
immune effector process GO:0002252 53 0.023
regulation of leukocyte activation GO:0002694 45 0.023
regulation of vasoconstriction GO:0019229 44 0.023
protein targeting to nucleus GO:0044744 35 0.023
negative regulation of blood circulation GO:1903523 20 0.023
transcription dna templated GO:0006351 377 0.023
intracellular steroid hormone receptor signaling pathway GO:0030518 20 0.022
positive regulation of cell projection organization GO:0031346 111 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
Yeast
sexual reproduction GO:0019953 148 0.022
response to reactive oxygen species GO:0000302 120 0.022
macromolecule catabolic process GO:0009057 58 0.022
pattern recognition receptor signaling pathway GO:0002221 9 0.022
protein maturation GO:0051604 68 0.022
endoplasmic reticulum unfolded protein response GO:0030968 2 0.022
actin filament based process GO:0030029 86 0.022
innate immune response GO:0045087 35 0.021
regulation of intracellular transport GO:0032386 65 0.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
cation transport GO:0006812 382 0.021
negative regulation of phosphate metabolic process GO:0045936 80 0.021
Rat
regulation of cell activation GO:0050865 50 0.020
cell recognition GO:0008037 11 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 13 0.020
rhythmic process GO:0048511 156 0.020
cellular protein complex assembly GO:0043623 44 0.020
negative regulation of neuron death GO:1901215 69 0.020
regulation of dna metabolic process GO:0051052 60 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
Rat
negative regulation of cysteine type endopeptidase activity GO:2000117 18 0.020
regulation of stress activated mapk cascade GO:0032872 23 0.020
immune response to tumor cell GO:0002418 3 0.020
regulation of neuron apoptotic process GO:0043523 83 0.020
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 2 0.020
synaptic vesicle endocytosis GO:0048488 4 0.020
muscle structure development GO:0061061 87 0.019
response to toxic substance GO:0009636 133 0.019
immune response regulating signaling pathway GO:0002764 19 0.019
muscle cell differentiation GO:0042692 52 0.019
chaperone cofactor dependent protein refolding GO:0070389 1 0.019
positive regulation of lamellipodium organization GO:1902745 4 0.019
neuron development GO:0048666 286 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
response to extracellular stimulus GO:0009991 380 0.019
nitric oxide biosynthetic process GO:0006809 23 0.019
negative regulation of cell development GO:0010721 82 0.019
regulation of membrane potential GO:0042391 110 0.019
response to cytokine GO:0034097 215 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
response to nutrient levels GO:0031667 370 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.018
protein processing GO:0016485 68 0.018
modification dependent protein catabolic process GO:0019941 14 0.018
negative regulation of protein processing GO:0010955 47 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
organelle assembly GO:0070925 22 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
negative regulation of phosphorylation GO:0042326 57 0.018
Rat
negative regulation of intracellular signal transduction GO:1902532 38 0.018
circulatory system development GO:0072359 134 0.018
Rat
cellular amine metabolic process GO:0044106 38 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
Rat
negative regulation of protein modification process GO:0031400 52 0.017
Rat
ribose phosphate metabolic process GO:0019693 235 0.017
Yeast
regulation of rna metabolic process GO:0051252 391 0.017
lamellipodium organization GO:0097581 5 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
fatty acid metabolic process GO:0006631 99 0.017
response to inorganic substance GO:0010035 377 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
lymphocyte activation involved in immune response GO:0002285 3 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
Yeast
anatomical structure homeostasis GO:0060249 29 0.017
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.016
regulation of cell proliferation GO:0042127 359 0.016
regulation of cellular component size GO:0032535 51 0.016
cellular macromolecular complex assembly GO:0034622 58 0.016
protein heterooligomerization GO:0051291 89 0.016
single organism membrane organization GO:0044802 74 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
neurological system process GO:0050877 219 0.016
ion transmembrane transport GO:0034220 365 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
positive regulation of leukocyte activation GO:0002696 30 0.016
nitric oxide metabolic process GO:0046209 26 0.015
activation of cysteine type endopeptidase activity GO:0097202 4 0.015
ossification GO:0001503 70 0.015
organic acid metabolic process GO:0006082 292 0.015
mitotic spindle organization GO:0007052 2 0.015
response to growth factor GO:0070848 189 0.015
negative regulation of cell communication GO:0010648 158 0.015
positive regulation of cell migration GO:0030335 96 0.015
metal ion transport GO:0030001 289 0.015
response to antibiotic GO:0046677 39 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
Yeast
positive regulation of response to stimulus GO:0048584 285 0.015
cytokine production GO:0001816 61 0.015
somatic diversification of immunoglobulins GO:0016445 1 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
response to wounding GO:0009611 254 0.014
regulation of bmp signaling pathway GO:0030510 2 0.014
regulation of interleukin 6 production GO:0032675 12 0.014
muscle cell development GO:0055001 26 0.014

Hsph1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
central nervous system disease DOID:331 0 0.034
sensory system disease DOID:0050155 0 0.020