Rattus norvegicus

0 known processes

She

Src homology 2 domain containing E

(Aliases: RGD1563897)

She biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.055
programmed cell death GO:0012501 392 0.051
regulation of phosphorus metabolic process GO:0051174 349 0.048
regulation of cell proliferation GO:0042127 359 0.046
positive regulation of developmental process GO:0051094 283 0.045
regulation of programmed cell death GO:0043067 341 0.044
homeostatic process GO:0042592 331 0.044
regulation of signal transduction GO:0009966 318 0.044
regulation of multicellular organismal development GO:2000026 376 0.043
oxoacid metabolic process GO:0043436 290 0.043
cardiovascular system development GO:0072358 134 0.042
catabolic process GO:0009056 351 0.041
apoptotic process GO:0006915 381 0.040
regulation of catalytic activity GO:0050790 304 0.039
cellular homeostasis GO:0019725 252 0.039
negative regulation of cellular metabolic process GO:0031324 281 0.038
inflammatory response GO:0006954 150 0.037
regulation of cell development GO:0060284 263 0.036
response to estrogen GO:0043627 232 0.035
single organism catabolic process GO:0044712 283 0.035
regulation of apoptotic process GO:0042981 335 0.035
organic substance catabolic process GO:1901575 316 0.035
response to extracellular stimulus GO:0009991 380 0.034
response to oxygen levels GO:0070482 265 0.034
cellular catabolic process GO:0044248 295 0.033
cellular amino acid metabolic process GO:0006520 107 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
response to bacterium GO:0009617 200 0.032
circulatory system development GO:0072359 134 0.031
regulation of cell differentiation GO:0045595 320 0.030
carboxylic acid metabolic process GO:0019752 289 0.030
purine nucleotide metabolic process GO:0006163 229 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
nucleoside metabolic process GO:0009116 179 0.029
intracellular signal transduction GO:0035556 314 0.029
nucleoside phosphate catabolic process GO:1901292 140 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
cell projection organization GO:0030030 302 0.028
organic acid metabolic process GO:0006082 292 0.028
negative regulation of cell death GO:0060548 229 0.028
neurological system process GO:0050877 219 0.028
positive regulation of molecular function GO:0044093 230 0.027
organophosphate metabolic process GO:0019637 370 0.027
regulation of molecular function GO:0065009 398 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
regulation of cellular component organization GO:0051128 368 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
chemical homeostasis GO:0048878 292 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
rna biosynthetic process GO:0032774 380 0.026
protein phosphorylation GO:0006468 345 0.026
response to hypoxia GO:0001666 231 0.026
glycosyl compound metabolic process GO:1901657 182 0.025
cellular response to external stimulus GO:0071496 118 0.025
response to inorganic substance GO:0010035 377 0.025
response to monosaccharide GO:0034284 159 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
cellular component biogenesis GO:0044085 368 0.025
heterocycle catabolic process GO:0046700 167 0.025
cellular component assembly GO:0022607 360 0.025
defense response GO:0006952 194 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
ion homeostasis GO:0050801 212 0.024
response to nutrient levels GO:0031667 370 0.024
negative regulation of metabolic process GO:0009892 331 0.024
rna metabolic process GO:0016070 406 0.023
response to carbohydrate GO:0009743 183 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
purine containing compound metabolic process GO:0072521 253 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
amine metabolic process GO:0009308 38 0.023
immune system process GO:0002376 204 0.023
cellular response to stress GO:0033554 269 0.022
response to decreased oxygen levels GO:0036293 237 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
nucleotide metabolic process GO:0009117 279 0.021
cellular amine metabolic process GO:0044106 38 0.021
cation transport GO:0006812 382 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
negative regulation of developmental process GO:0051093 125 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
cellular nitrogen compound catabolic process GO:0044270 163 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
neuron differentiation GO:0030182 368 0.020
cellular response to abiotic stimulus GO:0071214 85 0.020
female pregnancy GO:0007565 122 0.020
purine ribonucleoside catabolic process GO:0046130 124 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
circulatory system process GO:0003013 183 0.020
metal ion homeostasis GO:0055065 186 0.020
negative regulation of gene expression GO:0010629 199 0.020
negative regulation of molecular function GO:0044092 133 0.020
transcription dna templated GO:0006351 377 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.019
regulation of hydrolase activity GO:0051336 143 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
response to reactive oxygen species GO:0000302 120 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
ribonucleoside triphosphate metabolic process GO:0009199 141 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
negative regulation of cell communication GO:0010648 158 0.019
cellular component morphogenesis GO:0032989 155 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
nucleic acid templated transcription GO:0097659 379 0.018
liver development GO:0001889 90 0.018
immune response GO:0006955 104 0.018
response to nutrient GO:0007584 248 0.018
regulation of neuron differentiation GO:0045664 208 0.018
response to ketone GO:1901654 182 0.018
regulation of nervous system development GO:0051960 264 0.018
transmission of nerve impulse GO:0019226 42 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
secretion GO:0046903 307 0.018
cellular chemical homeostasis GO:0055082 247 0.017
aromatic compound catabolic process GO:0019439 168 0.017
response to peptide hormone GO:0043434 278 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
regulation of neurogenesis GO:0050767 247 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
regulation of catabolic process GO:0009894 113 0.017
response to peptide GO:1901652 292 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
response to oxidative stress GO:0006979 186 0.017
cellular component movement GO:0006928 248 0.017
neuron development GO:0048666 286 0.016
organophosphate catabolic process GO:0046434 148 0.016
cellular ketone metabolic process GO:0042180 51 0.016
muscle system process GO:0003012 115 0.016
action potential GO:0001508 54 0.016
response to growth factor GO:0070848 189 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
response to glucose GO:0009749 136 0.016
multicellular organismal signaling GO:0035637 44 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
response to estradiol GO:0032355 164 0.016
blood vessel development GO:0001568 69 0.016
central nervous system development GO:0007417 311 0.016
positive regulation of signaling GO:0023056 270 0.016
calcium ion homeostasis GO:0055074 162 0.016
tissue development GO:0009888 252 0.016
regulation of system process GO:0044057 208 0.016
growth GO:0040007 165 0.016
ribonucleotide catabolic process GO:0009261 136 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
response to other organism GO:0051707 220 0.015
organelle organization GO:0006996 266 0.015
vesicle mediated transport GO:0016192 181 0.015
rhythmic process GO:0048511 156 0.015
regulation of transcription dna templated GO:0006355 374 0.015
angiogenesis GO:0001525 53 0.015
regulation of protein metabolic process GO:0051246 289 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
regulation of response to stress GO:0080134 126 0.015
protein transport GO:0015031 132 0.015
heart process GO:0003015 57 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
vasculature development GO:0001944 70 0.015
immunoglobulin mediated immune response GO:0016064 4 0.015
ribonucleoside catabolic process GO:0042454 126 0.014
hepaticobiliary system development GO:0061008 90 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
purine containing compound catabolic process GO:0072523 138 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
response to hexose GO:0009746 144 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
protein complex subunit organization GO:0071822 302 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
nucleotide catabolic process GO:0009166 139 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
positive regulation of cell development GO:0010720 176 0.014
response to ethanol GO:0045471 162 0.014
cell migration GO:0016477 197 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
regulation of membrane potential GO:0042391 110 0.014
gastrulation GO:0007369 2 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
positive regulation of cell death GO:0010942 184 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
cellular lipid metabolic process GO:0044255 208 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
single organism biosynthetic process GO:0044711 342 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
protein oligomerization GO:0051259 191 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
regulation of immune system process GO:0002682 123 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.013
regulation of cell projection organization GO:0031344 175 0.013
cation homeostasis GO:0055080 195 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
regeneration GO:0031099 163 0.013
protein complex assembly GO:0006461 263 0.013
single organism intracellular transport GO:1902582 166 0.013
neuron projection development GO:0031175 273 0.013
regulation of neuron projection development GO:0010975 161 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
multi organism reproductive process GO:0044703 262 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
regulation of phosphorylation GO:0042325 248 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
negative regulation of signaling GO:0023057 157 0.013
ras protein signal transduction GO:0007265 29 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
carbohydrate homeostasis GO:0033500 75 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
brain development GO:0007420 247 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
response to external biotic stimulus GO:0043207 221 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
blood vessel morphogenesis GO:0048514 58 0.013
oxidation reduction process GO:0055114 304 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
circadian rhythm GO:0007623 88 0.013
transmembrane transport GO:0055085 412 0.013
sexual reproduction GO:0019953 148 0.012
b cell mediated immunity GO:0019724 4 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of cell migration GO:0030334 128 0.012
positive regulation of cell communication GO:0010647 271 0.012
regulation of muscle system process GO:0090257 79 0.012
proteolysis GO:0006508 175 0.012
response to organophosphorus GO:0046683 102 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of muscle contraction GO:0006937 53 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
regulation of rna metabolic process GO:0051252 391 0.012
response to wounding GO:0009611 254 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
cell cell signaling GO:0007267 335 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
single organism reproductive process GO:0044702 297 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
response to insulin GO:0032868 133 0.012
behavior GO:0007610 205 0.012
single organism organelle organization GO:1902589 180 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
ion transmembrane transport GO:0034220 365 0.012
nucleoside catabolic process GO:0009164 126 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
cell type specific apoptotic process GO:0097285 134 0.011
regulation of transferase activity GO:0051338 123 0.011
gland development GO:0048732 155 0.011
negative regulation of innate immune response GO:0045824 4 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
metal ion transport GO:0030001 289 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
regulation of cellular component movement GO:0051270 150 0.011
bmp signaling pathway GO:0030509 4 0.011
reproduction GO:0000003 245 0.011
response to biotic stimulus GO:0009607 226 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
cellular cation homeostasis GO:0030003 180 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
head development GO:0060322 247 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
response to vitamin GO:0033273 131 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
protein complex biogenesis GO:0070271 263 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
cell part morphogenesis GO:0032990 123 0.011
neuron projection morphogenesis GO:0048812 122 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
regulation of dendrite development GO:0050773 59 0.011
single organism behavior GO:0044708 130 0.010
cellular ion homeostasis GO:0006873 184 0.010
muscle cell proliferation GO:0033002 84 0.010
response to mechanical stimulus GO:0009612 134 0.010
response to toxic substance GO:0009636 133 0.010
positive regulation of gtpase activity GO:0043547 47 0.010
response to activity GO:0014823 73 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
reproductive process GO:0022414 372 0.010
developmental process involved in reproduction GO:0003006 159 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
synaptic transmission GO:0007268 235 0.010
adult locomotory behavior GO:0008344 4 0.010
positive regulation of transferase activity GO:0051347 81 0.010

She disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012