Rattus norvegicus

0 known processes

Scn4b

sodium channel, voltage-gated, type IV, beta

Scn4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart contraction GO:0060047 57 0.208
Human
regulation of ion transport GO:0043269 245 0.186
Human Mouse Rat
homeostatic process GO:0042592 331 0.141
cardiac muscle contraction GO:0060048 27 0.122
Human
macromolecular complex assembly GO:0065003 273 0.119
blood circulation GO:0008015 183 0.102
Human
protein complex biogenesis GO:0070271 263 0.099
cation transport GO:0006812 382 0.096
Human Mouse Rat
macromolecular complex subunit organization GO:0043933 339 0.090
response to decreased oxygen levels GO:0036293 237 0.083
cellular component biogenesis GO:0044085 368 0.082
protein complex assembly GO:0006461 263 0.078
neuron differentiation GO:0030182 368 0.077
membrane depolarization during action potential GO:0086010 1 0.071
Human
response to peptide hormone GO:0043434 278 0.069
anatomical structure morphogenesis GO:0009653 298 0.065
cellular chemical homeostasis GO:0055082 247 0.063
cellular ion homeostasis GO:0006873 184 0.062
cellular component assembly GO:0022607 360 0.062
regulation of membrane potential GO:0042391 110 0.059
Human
carboxylic acid metabolic process GO:0019752 289 0.056
protein complex subunit organization GO:0071822 302 0.055
chemical homeostasis GO:0048878 292 0.053
inorganic cation transmembrane transport GO:0098662 202 0.053
Human Mouse Rat
cellular response to hormone stimulus GO:0032870 247 0.052
metal ion transport GO:0030001 289 0.052
Human Mouse Rat
response to carbohydrate GO:0009743 183 0.051
oxoacid metabolic process GO:0043436 290 0.051
neuron projection development GO:0031175 273 0.051
cellular response to organonitrogen compound GO:0071417 197 0.047
regulation of transcription dna templated GO:0006355 374 0.046
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.045
cell cycle GO:0007049 101 0.044
cell projection organization GO:0030030 302 0.044
regulation of protein metabolic process GO:0051246 289 0.044
regulation of membrane repolarization GO:0060306 1 0.044
Human
positive regulation of biosynthetic process GO:0009891 319 0.043
central nervous system development GO:0007417 311 0.043
positive regulation of gene expression GO:0010628 244 0.043
cellular response to endogenous stimulus GO:0071495 377 0.042
protein phosphorylation GO:0006468 345 0.042
circulatory system process GO:0003013 183 0.042
Human
response to peptide GO:1901652 292 0.041
cellular response to peptide hormone stimulus GO:0071375 120 0.041
organic acid metabolic process GO:0006082 292 0.041
response to oxygen levels GO:0070482 265 0.039
divalent metal ion transport GO:0070838 132 0.038
cardiac muscle cell contraction GO:0086003 10 0.038
rhythmic process GO:0048511 156 0.037
organelle organization GO:0006996 266 0.036
action potential GO:0001508 54 0.035
Human
response to inorganic substance GO:0010035 377 0.035
membrane repolarization GO:0086009 1 0.034
Human
response to hypoxia GO:0001666 231 0.034
negative regulation of transport GO:0051051 136 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
cellular response to peptide GO:1901653 133 0.032
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.032
response to estrogen GO:0043627 232 0.032
positive regulation of developmental process GO:0051094 283 0.031
cardiovascular system development GO:0072358 134 0.031
ion homeostasis GO:0050801 212 0.031
cellular homeostasis GO:0019725 252 0.031
cellular cation homeostasis GO:0030003 180 0.030
multi organism reproductive process GO:0044703 262 0.030
cation transmembrane transport GO:0098655 263 0.030
Human Mouse Rat
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.030
cytosolic calcium ion homeostasis GO:0051480 140 0.030
cellular response to oxygen containing compound GO:1901701 386 0.030
response to monosaccharide GO:0034284 159 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.029
regulation of programmed cell death GO:0043067 341 0.029
cell cell signaling GO:0007267 335 0.029
sodium ion transport GO:0006814 82 0.029
Human Mouse Rat
calcium ion homeostasis GO:0055074 162 0.029
cell communication involved in cardiac conduction GO:0086065 2 0.029
Human
cellular calcium ion homeostasis GO:0006874 160 0.028
regulation of apoptotic process GO:0042981 335 0.028
neuron development GO:0048666 286 0.028
metal ion homeostasis GO:0055065 186 0.028
regulation of cell differentiation GO:0045595 320 0.028
heart process GO:0003015 57 0.027
Human
carbohydrate derivative metabolic process GO:1901135 346 0.027
head development GO:0060322 247 0.027
regulation of neuron differentiation GO:0045664 208 0.027
regulation of system process GO:0044057 208 0.027
Human
response to glucocorticoid GO:0051384 223 0.026
defense response GO:0006952 194 0.026
protein oligomerization GO:0051259 191 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
response to insulin GO:0032868 133 0.025
cation homeostasis GO:0055080 195 0.025
multicellular organismal signaling GO:0035637 44 0.025
Human
cellular amino acid metabolic process GO:0006520 107 0.025
macromolecule localization GO:0033036 252 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
regulation of heart contraction GO:0008016 48 0.024
Human
striated muscle contraction GO:0006941 44 0.024
Human
regulation of phosphate metabolic process GO:0019220 349 0.024
regulation of metal ion transport GO:0010959 118 0.024
Human
behavior GO:0007610 205 0.024
positive regulation of cell death GO:0010942 184 0.024
regulation of molecular function GO:0065009 398 0.024
Human
regulation of nervous system development GO:0051960 264 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
apoptotic process GO:0006915 381 0.023
positive regulation of transport GO:0051050 245 0.023
Human
multicellular organism reproduction GO:0032504 233 0.023
cellular amine metabolic process GO:0044106 38 0.023
neuron projection morphogenesis GO:0048812 122 0.023
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.023
Human
regulation of cell proliferation GO:0042127 359 0.023
divalent inorganic cation transport GO:0072511 134 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
brain development GO:0007420 247 0.023
endoplasmic reticulum to cytosol transport GO:1903513 4 0.022
regulation of neuron projection development GO:0010975 161 0.022
response to acid chemical GO:0001101 222 0.022
response to hexose GO:0009746 144 0.022
response to bacterium GO:0009617 200 0.022
response to alkaloid GO:0043279 132 0.022
reproductive process GO:0022414 372 0.022
regulation of catabolic process GO:0009894 113 0.022
amine metabolic process GO:0009308 38 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
muscle contraction GO:0006936 88 0.021
Human
response to metal ion GO:0010038 253 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
glial cell differentiation GO:0010001 65 0.021
regulation of cellular component organization GO:0051128 368 0.021
rhythmic behavior GO:0007622 24 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
cellular component movement GO:0006928 248 0.020
response to glucose GO:0009749 136 0.020
regulation of cell development GO:0060284 263 0.020
regulation of fat cell proliferation GO:0070344 1 0.019
regulation of anatomical structure size GO:0090066 135 0.019
response to ethanol GO:0045471 162 0.019
neuronal action potential GO:0019228 35 0.019
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.019
Human
purine containing compound metabolic process GO:0072521 253 0.019
circadian rhythm GO:0007623 88 0.019
positive regulation of molecular function GO:0044093 230 0.019
circulatory system development GO:0072359 134 0.019
regulation of protein modification process GO:0031399 194 0.019
response to hyperoxia GO:0055093 45 0.019
rna biosynthetic process GO:0032774 380 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
transcription dna templated GO:0006351 377 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
programmed cell death GO:0012501 392 0.018
heart morphogenesis GO:0003007 3 0.018
single organism catabolic process GO:0044712 283 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
gliogenesis GO:0042063 93 0.018
protein localization GO:0008104 191 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
regulation of fat cell differentiation GO:0045598 3 0.017
chemosensory behavior GO:0007635 2 0.017
oxidation reduction process GO:0055114 304 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
response to oxidative stress GO:0006979 186 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
regulation of blood circulation GO:1903522 110 0.017
Human
response to biotic stimulus GO:0009607 226 0.017
cell growth GO:0016049 104 0.017
neurological system process GO:0050877 219 0.017
regulation of muscle system process GO:0090257 79 0.017
Human
cardiac conduction GO:0061337 2 0.017
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
potassium ion homeostasis GO:0055075 2 0.017
regulation of cell projection organization GO:0031344 175 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
response to cytokine GO:0034097 215 0.017
cellular response to insulin stimulus GO:0032869 81 0.017
catabolic process GO:0009056 351 0.016
single organism behavior GO:0044708 130 0.016
regulation of catalytic activity GO:0050790 304 0.016
negative regulation of signaling GO:0023057 157 0.016
organophosphate metabolic process GO:0019637 370 0.016
aging GO:0007568 241 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
positive regulation of cell development GO:0010720 176 0.016
transmembrane transport GO:0055085 412 0.015
Human Mouse Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of neurogenesis GO:0050767 247 0.015
positive regulation of protein modification process GO:0031401 142 0.015
response to corticosteroid GO:0031960 235 0.015
response to lipopolysaccharide GO:0032496 191 0.015
single organism organelle organization GO:1902589 180 0.015
regeneration GO:0031099 163 0.015
single organism reproductive process GO:0044702 297 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
response to radiation GO:0009314 137 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
dicarboxylic acid metabolic process GO:0043648 42 0.015
response to external biotic stimulus GO:0043207 221 0.014
cellular ketone metabolic process GO:0042180 51 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
positive regulation of nervous system development GO:0051962 178 0.014
regulation of cellular localization GO:0060341 263 0.014
organ regeneration GO:0031100 101 0.014
organic substance catabolic process GO:1901575 316 0.014
regulation of cellular component movement GO:0051270 150 0.014
Human
response to extracellular stimulus GO:0009991 380 0.014
anterior posterior pattern specification GO:0009952 1 0.014
positive regulation of signal transduction GO:0009967 175 0.014
actin filament based process GO:0030029 86 0.014
nucleic acid templated transcription GO:0097659 379 0.014
sodium ion transmembrane transport GO:0035725 67 0.014
Human Mouse Rat
positive regulation of protein metabolic process GO:0051247 178 0.014
protein heterooligomerization GO:0051291 89 0.014
regulation of hydrolase activity GO:0051336 143 0.014
angiogenesis GO:0001525 53 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
axis specification GO:0009798 4 0.014
multi multicellular organism process GO:0044706 138 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
cell part morphogenesis GO:0032990 123 0.014
protein transport GO:0015031 132 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
response to transition metal nanoparticle GO:1990267 122 0.013
response to growth factor GO:0070848 189 0.013
tissue development GO:0009888 252 0.013
reproduction GO:0000003 245 0.013
response to reactive oxygen species GO:0000302 120 0.013
rna metabolic process GO:0016070 406 0.013
metestrus GO:0060210 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
muscle system process GO:0003012 115 0.013
Human
cellular response to external stimulus GO:0071496 118 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
regulation of cell cycle GO:0051726 73 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
cellular protein complex assembly GO:0043623 44 0.013
heart development GO:0007507 72 0.013
regulation of synaptic transmission GO:0050804 141 0.013
potassium ion transport GO:0006813 97 0.012
developmental process involved in reproduction GO:0003006 159 0.012
regulation of blood vessel size GO:0050880 89 0.012
establishment of protein localization GO:0045184 141 0.012
actin mediated cell contraction GO:0070252 12 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
secretion by cell GO:0032940 248 0.012
cell morphogenesis GO:0000902 142 0.012
regulation of tube size GO:0035150 89 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
palate development GO:0060021 2 0.012
regulation of organ formation GO:0003156 2 0.012
proteolysis GO:0006508 175 0.012
intracellular signal transduction GO:0035556 314 0.012
vasculature development GO:0001944 70 0.012
gland development GO:0048732 155 0.012
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
positive regulation of ion transport GO:0043270 94 0.012
Human
circadian behavior GO:0048512 24 0.012
vascular process in circulatory system GO:0003018 96 0.012
striated muscle tissue development GO:0014706 58 0.012
regulation of striated muscle contraction GO:0006942 21 0.012
Human
positive regulation of phosphorylation GO:0042327 177 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
single organism intracellular transport GO:1902582 166 0.011
dna metabolic process GO:0006259 96 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
response to hydrogen peroxide GO:0042542 89 0.011
positive regulation of signaling GO:0023056 270 0.011
secretion GO:0046903 307 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
fatty acid metabolic process GO:0006631 99 0.011
muscle tissue development GO:0060537 58 0.011
cell cycle process GO:0022402 57 0.011
organ morphogenesis GO:0009887 75 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
sequestering of calcium ion GO:0051208 8 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
Human Mouse Rat
negative regulation of cell communication GO:0010648 158 0.011
calcium ion transport GO:0006816 131 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
inflammatory response GO:0006954 150 0.011
regulation of muscle contraction GO:0006937 53 0.011
Human
growth GO:0040007 165 0.011
cellular macromolecule localization GO:0070727 122 0.011
nucleoside metabolic process GO:0009116 179 0.011
cytokine biosynthetic process GO:0042089 3 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
Human Mouse Rat
immune system process GO:0002376 204 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
calcium ion transmembrane transport GO:0070588 70 0.010
ovulation cycle process GO:0022602 50 0.010
organophosphate catabolic process GO:0046434 148 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
protein dephosphorylation GO:0006470 38 0.010
reproductive system development GO:0061458 128 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
Human Mouse Rat
transmission of nerve impulse GO:0019226 42 0.010
lipid storage GO:0019915 1 0.010

Scn4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
sensory system disease DOID:0050155 0 0.014