Rattus norvegicus

73 known processes

Apc

adenomatous polyposis coli

(Aliases: RATAPC)

Apc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.348
regulation of signal transduction GO:0009966 318 0.316
Human Fly
purine ribonucleotide catabolic process GO:0009154 136 0.306
protein phosphorylation GO:0006468 345 0.284
Human
regulation of intracellular signal transduction GO:1902531 218 0.251
protein complex assembly GO:0006461 263 0.248
Human Fly
cell morphogenesis GO:0000902 142 0.231
Fly
neuron development GO:0048666 286 0.197
cell morphogenesis involved in differentiation GO:0000904 119 0.191
Fly
positive regulation of transport GO:0051050 245 0.181
regulation of cellular localization GO:0060341 263 0.162
Human
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.145
Fly
secretion GO:0046903 307 0.133
axonogenesis GO:0007409 71 0.131
Fly
positive regulation of catalytic activity GO:0043085 184 0.131
monovalent inorganic cation transport GO:0015672 172 0.130
programmed cell death GO:0012501 392 0.124
Human Fly
single organism organelle organization GO:1902589 180 0.122
Human Fly
vesicle mediated transport GO:0016192 181 0.119
organophosphate metabolic process GO:0019637 370 0.118
organonitrogen compound catabolic process GO:1901565 179 0.118
regulation of secretion by cell GO:1903530 208 0.116
cell cell signaling GO:0007267 335 0.111
regulation of cellular component organization GO:0051128 368 0.107
Human Fly
regulation of phosphorylation GO:0042325 248 0.098
Human
neuron projection development GO:0031175 273 0.097
regulation of phosphate metabolic process GO:0019220 349 0.097
Human
neuron differentiation GO:0030182 368 0.096
organelle organization GO:0006996 266 0.092
Human Fly
axon development GO:0061564 96 0.091
Fly
positive regulation of nucleotide metabolic process GO:0045981 91 0.091
purine containing compound catabolic process GO:0072523 138 0.089
purine ribonucleoside metabolic process GO:0046128 168 0.087
mesonephric tubule development GO:0072164 14 0.087
single organism membrane organization GO:0044802 74 0.086
purine nucleoside metabolic process GO:0042278 169 0.086
anatomical structure morphogenesis GO:0009653 298 0.085
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.085
negative regulation of metabolic process GO:0009892 331 0.084
Human
neurotransmitter gated ion channel clustering GO:0072578 3 0.084
regulation of vesicle mediated transport GO:0060627 81 0.082
signal transduction by phosphorylation GO:0023014 144 0.082
cellular component biogenesis GO:0044085 368 0.082
Human Fly
positive regulation of multicellular organismal process GO:0051240 387 0.080
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.080
regulation of kinase activity GO:0043549 117 0.079
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.076
ribonucleoside triphosphate metabolic process GO:0009199 141 0.074
amine metabolic process GO:0009308 38 0.072
biological adhesion GO:0022610 110 0.071
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.071
Human
macromolecular complex assembly GO:0065003 273 0.070
Human Fly
cell projection organization GO:0030030 302 0.069
positive regulation of cellular component organization GO:0051130 200 0.069
Human Fly
regulation of cytoskeleton organization GO:0051493 49 0.069
Human
regulation of cellular protein metabolic process GO:0032268 267 0.068
Human
cell projection morphogenesis GO:0048858 123 0.068
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.068
single organism catabolic process GO:0044712 283 0.067
Human
secretion by cell GO:0032940 248 0.066
positive regulation of secretion GO:0051047 140 0.065
gtp catabolic process GO:0006184 71 0.065
positive regulation of cell communication GO:0010647 271 0.064
regulation of molecular function GO:0065009 398 0.063
Human
positive regulation of secretion by cell GO:1903532 128 0.063
ribonucleoside triphosphate catabolic process GO:0009203 122 0.062
cell part morphogenesis GO:0032990 123 0.062
Fly
cellular response to oxygen containing compound GO:1901701 386 0.062
cellular component assembly GO:0022607 360 0.060
Human Fly
positive regulation of neurogenesis GO:0050769 165 0.059
regulation of synaptic transmission GO:0050804 141 0.058
nucleoside triphosphate catabolic process GO:0009143 123 0.058
nucleoside triphosphate metabolic process GO:0009141 144 0.058
ribonucleotide metabolic process GO:0009259 231 0.058
regulation of multicellular organismal development GO:2000026 376 0.058
Fly
apoptotic process GO:0006915 381 0.058
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.057
regulation of mapk cascade GO:0043408 116 0.057
regulation of cellular ketone metabolic process GO:0010565 27 0.056
carboxylic acid metabolic process GO:0019752 289 0.056
cytoskeleton organization GO:0007010 111 0.055
Human Fly
regulation of secretion GO:0051046 224 0.055
glycosyl compound metabolic process GO:1901657 182 0.055
positive regulation of response to stimulus GO:0048584 285 0.054
positive regulation of phosphorus metabolic process GO:0010562 262 0.053
homeostatic process GO:0042592 331 0.053
membrane organization GO:0061024 94 0.053
macromolecular complex subunit organization GO:0043933 339 0.053
Human Fly
purine nucleotide metabolic process GO:0006163 229 0.053
nucleoside phosphate catabolic process GO:1901292 140 0.052
embryonic pattern specification GO:0009880 1 0.052
regulation of cell differentiation GO:0045595 320 0.051
Fly
ras protein signal transduction GO:0007265 29 0.051
nucleobase containing compound catabolic process GO:0034655 152 0.050
positive regulation of cell proliferation GO:0008284 249 0.050
purine ribonucleotide metabolic process GO:0009150 227 0.050
cellular metal ion homeostasis GO:0006875 172 0.050
positive regulation of intracellular signal transduction GO:1902533 138 0.049
nucleoside catabolic process GO:0009164 126 0.049
purine ribonucleoside catabolic process GO:0046130 124 0.047
organic cyclic compound catabolic process GO:1901361 175 0.047
purine nucleoside catabolic process GO:0006152 124 0.047
receptor localization to synapse GO:0097120 2 0.047
positive regulation of phosphate metabolic process GO:0045937 262 0.046
cellular response to stress GO:0033554 269 0.046
Human
regulation of protein modification process GO:0031399 194 0.046
Human
cation homeostasis GO:0055080 195 0.046
organic substance catabolic process GO:1901575 316 0.045
Human Fly
nucleotide catabolic process GO:0009166 139 0.045
catabolic process GO:0009056 351 0.044
Human Fly
regulation of endocytosis GO:0030100 42 0.044
positive regulation of molecular function GO:0044093 230 0.044
protein complex subunit organization GO:0071822 302 0.044
Human Fly
regulation of protein phosphorylation GO:0001932 183 0.044
Human
purine nucleoside triphosphate metabolic process GO:0009144 141 0.044
positive regulation of phosphorylation GO:0042327 177 0.044
positive regulation of signaling GO:0023056 270 0.044
nucleoside phosphate metabolic process GO:0006753 283 0.044
positive regulation of gene expression GO:0010628 244 0.042
multicellular organism growth GO:0035264 1 0.041
regulation of purine nucleotide catabolic process GO:0033121 65 0.041
regulation of cellular amine metabolic process GO:0033238 8 0.040
heterocycle catabolic process GO:0046700 167 0.040
regulation of transcription dna templated GO:0006355 374 0.040
positive regulation of hydrolase activity GO:0051345 86 0.040
organophosphate catabolic process GO:0046434 148 0.040
central nervous system development GO:0007417 311 0.040
Fly
release of cytochrome c from mitochondria GO:0001836 8 0.040
response to nutrient levels GO:0031667 370 0.039
positive regulation of inhibitory postsynaptic membrane potential GO:0097151 3 0.039
behavior GO:0007610 205 0.039
regulation of proteasomal protein catabolic process GO:0061136 4 0.039
Human
ribose phosphate metabolic process GO:0019693 235 0.038
small gtpase mediated signal transduction GO:0007264 36 0.038
positive regulation of ion transport GO:0043270 94 0.038
carbohydrate derivative catabolic process GO:1901136 147 0.038
cellular amine metabolic process GO:0044106 38 0.038
positive regulation of developmental process GO:0051094 283 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.037
establishment of organelle localization GO:0051656 37 0.037
Fly
regulation of protein kinase activity GO:0045859 105 0.037
Human
nucleoside metabolic process GO:0009116 179 0.037
cellular catabolic process GO:0044248 295 0.037
Human
ribonucleoside metabolic process GO:0009119 174 0.037
actin cytoskeleton organization GO:0030036 73 0.037
Fly
neuron projection morphogenesis GO:0048812 122 0.036
Fly
ribonucleoside catabolic process GO:0042454 126 0.036
divalent inorganic cation homeostasis GO:0072507 165 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.036
cellular nitrogen compound catabolic process GO:0044270 163 0.035
nucleic acid templated transcription GO:0097659 379 0.035
cell adhesion GO:0007155 110 0.035
Fly
positive regulation of cell development GO:0010720 176 0.035
dendrite development GO:0016358 72 0.035
cellular component morphogenesis GO:0032989 155 0.034
Fly
head development GO:0060322 247 0.034
Fly
positive regulation of protein phosphorylation GO:0001934 135 0.034
regulation of purine nucleotide metabolic process GO:1900542 115 0.034
mapk cascade GO:0000165 140 0.034
regulation of organelle organization GO:0033043 80 0.033
Human
organic acid metabolic process GO:0006082 292 0.033
glycosyl compound catabolic process GO:1901658 126 0.033
positive regulation of nervous system development GO:0051962 178 0.033
male mating behavior GO:0060179 3 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
negative regulation of cell communication GO:0010648 158 0.032
Human Fly
positive regulation of biosynthetic process GO:0009891 319 0.032
protein complex biogenesis GO:0070271 263 0.032
Human Fly
synaptic vesicle docking involved in exocytosis GO:0016081 2 0.032
regulation of cellular catabolic process GO:0031329 101 0.032
Human
regulation of metal ion transport GO:0010959 118 0.032
regulation of ion transport GO:0043269 245 0.032
dendritic spine morphogenesis GO:0060997 9 0.032
regulation of protein serine threonine kinase activity GO:0071900 64 0.031
Human
multi organism reproductive process GO:0044703 262 0.031
Fly
regulation of transferase activity GO:0051338 123 0.031
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
cation transport GO:0006812 382 0.031
regulation of programmed cell death GO:0043067 341 0.031
Human Fly
regulation of cell proliferation GO:0042127 359 0.031
Human
gastrulation GO:0007369 2 0.031
regulation of map kinase activity GO:0043405 53 0.030
response to inorganic substance GO:0010035 377 0.030
synaptic vesicle priming GO:0016082 4 0.030
ion transmembrane transport GO:0034220 365 0.030
regulation of protein metabolic process GO:0051246 289 0.030
Human Fly
oxoacid metabolic process GO:0043436 290 0.030
positive regulation of protein modification process GO:0031401 142 0.029
cellular homeostasis GO:0019725 252 0.029
synaptic growth at neuromuscular junction GO:0051124 1 0.029
enzyme linked receptor protein signaling pathway GO:0007167 116 0.029
sodium ion transport GO:0006814 82 0.029
positive regulation of synaptic vesicle transport GO:1902805 3 0.029
ribonucleotide catabolic process GO:0009261 136 0.028
cell type specific apoptotic process GO:0097285 134 0.028
cellular ion homeostasis GO:0006873 184 0.028
purine nucleoside triphosphate catabolic process GO:0009146 122 0.028
synaptic transmission GO:0007268 235 0.028
aromatic compound catabolic process GO:0019439 168 0.028
nucleotide metabolic process GO:0009117 279 0.028
guanosine containing compound catabolic process GO:1901069 71 0.027
regulation of catalytic activity GO:0050790 304 0.027
Human
cellular calcium ion homeostasis GO:0006874 160 0.027
cellular ketone metabolic process GO:0042180 51 0.027
dendrite morphogenesis GO:0048813 43 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.027
positive regulation of nucleotide catabolic process GO:0030813 53 0.027
regulation of cell cycle GO:0051726 73 0.026
Human
regulation of synaptic plasticity GO:0048167 70 0.026
positive regulation of gtpase activity GO:0043547 47 0.026
exocytosis GO:0006887 60 0.026
embryonic skeletal system morphogenesis GO:0048704 3 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
metal ion homeostasis GO:0055065 186 0.026
protein autophosphorylation GO:0046777 66 0.026
locomotion GO:0040011 237 0.026
Human Fly
synaptic vesicle exocytosis GO:0016079 15 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
synaptic vesicle endocytosis GO:0048488 4 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
ion homeostasis GO:0050801 212 0.025
positive regulation of gtp catabolic process GO:0033126 48 0.025
activation of protein kinase activity GO:0032147 47 0.025
protein localization GO:0008104 191 0.025
Human Fly
regulation of protein transport GO:0051223 68 0.025
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
Human
anterior posterior pattern specification GO:0009952 1 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
rna biosynthetic process GO:0032774 380 0.024
positive regulation of kinase activity GO:0033674 77 0.024
macroautophagy GO:0016236 4 0.024
regulation of sodium ion transport GO:0002028 21 0.024
organelle localization GO:0051640 55 0.024
Fly
regulation of membrane potential GO:0042391 110 0.024
embryonic skeletal system development GO:0048706 3 0.024
positive regulation of nucleoside metabolic process GO:0045979 55 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
Human
regulation of rna biosynthetic process GO:2001141 381 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
response to radiation GO:0009314 137 0.023
cellular chemical homeostasis GO:0055082 247 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
axis specification GO:0009798 4 0.023
neurological system process GO:0050877 219 0.023
positive regulation of transferase activity GO:0051347 81 0.023
cell cycle GO:0007049 101 0.023
Human
endomembrane system organization GO:0010256 48 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
negative regulation of phosphorus metabolic process GO:0010563 80 0.022
Human
cellular cation homeostasis GO:0030003 180 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
Fly
cellular component movement GO:0006928 248 0.022
Human Fly
response to peptide hormone GO:0043434 278 0.022
neurotransmitter secretion GO:0007269 33 0.022
brain development GO:0007420 247 0.022
Fly
chemical homeostasis GO:0048878 292 0.021
purine containing compound metabolic process GO:0072521 253 0.021
cell motility GO:0048870 202 0.021
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.021
asymmetric protein localization GO:0008105 2 0.021
sexual reproduction GO:0019953 148 0.021
Fly
cell cycle checkpoint GO:0000075 2 0.021
Human
regulation of nucleotide metabolic process GO:0006140 117 0.021
negative regulation of transport GO:0051051 136 0.021
neuronal action potential GO:0019228 35 0.021
regulation of developmental growth GO:0048638 45 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
Human Fly
regulation of nucleotide catabolic process GO:0030811 65 0.021
response to cytokine GO:0034097 215 0.021
response to growth factor GO:0070848 189 0.021
guanosine containing compound metabolic process GO:1901068 74 0.021
transmembrane transport GO:0055085 412 0.021
calcium ion homeostasis GO:0055074 162 0.021
circadian rhythm GO:0007623 88 0.021
regulation of nervous system development GO:0051960 264 0.021
embryonic axis specification GO:0000578 1 0.021
single organismal cell cell adhesion GO:0016337 42 0.020
Fly
response to mechanical stimulus GO:0009612 134 0.020
protein processing GO:0016485 68 0.020
Human
negative regulation of transcription dna templated GO:0045892 116 0.020
synaptic vesicle localization GO:0097479 24 0.020
regulation of anatomical structure size GO:0090066 135 0.020
peptidyl amino acid modification GO:0018193 126 0.020
regulation of cell development GO:0060284 263 0.020
Fly
regulation of cell projection organization GO:0031344 175 0.020
Human
developmental growth GO:0048589 100 0.020
positive regulation of apoptotic process GO:0043065 154 0.019
Human
transcription dna templated GO:0006351 377 0.019
developmental process involved in reproduction GO:0003006 159 0.019
Fly
single organism behavior GO:0044708 130 0.019
immune system process GO:0002376 204 0.019
rna metabolic process GO:0016070 406 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
response to peptide GO:1901652 292 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
gamete generation GO:0007276 124 0.019
Fly
axon guidance GO:0007411 24 0.019
Fly
purine nucleotide catabolic process GO:0006195 136 0.019
action potential GO:0001508 54 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
establishment of synaptic vesicle localization GO:0097480 23 0.018
regulation of neurogenesis GO:0050767 247 0.018
positive regulation of cellular catabolic process GO:0031331 71 0.018
jak stat cascade GO:0007259 26 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
regulation of smoothened signaling pathway GO:0008589 2 0.018
cell growth GO:0016049 104 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
receptor mediated endocytosis GO:0006898 42 0.018
positive regulation of signal transduction GO:0009967 175 0.018
dendritic spine organization GO:0097061 12 0.018
response to metal ion GO:0010038 253 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
inorganic cation transmembrane transport GO:0098662 202 0.017
regulation of neuron projection development GO:0010975 161 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
Fly
regulation of postsynaptic membrane potential GO:0060078 25 0.017
aging GO:0007568 241 0.017
protein oligomerization GO:0051259 191 0.017
cell migration GO:0016477 197 0.017
Human
neuronal ion channel clustering GO:0045161 3 0.017
potassium ion transport GO:0006813 97 0.017
synapse organization GO:0050808 46 0.017
lipid metabolic process GO:0006629 283 0.017
tube formation GO:0035148 3 0.017
growth GO:0040007 165 0.017
glutamate receptor signaling pathway GO:0007215 43 0.016
regulation of neuron differentiation GO:0045664 208 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
Fly
regulation of body fluid levels GO:0050878 90 0.016
circulatory system process GO:0003013 183 0.016
reproduction GO:0000003 245 0.016
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
cellular protein complex assembly GO:0043623 44 0.016
neuron death GO:0070997 127 0.016
cell cell signaling involved in cell fate commitment GO:0045168 2 0.016
gtp metabolic process GO:0046039 72 0.015
erbb signaling pathway GO:0038127 23 0.015
learning or memory GO:0007611 90 0.015
regulation of hydrolase activity GO:0051336 143 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
anion transport GO:0006820 178 0.015
microtubule cytoskeleton organization GO:0000226 25 0.015
Human Fly
negative regulation of receptor internalization GO:0002091 2 0.015
response to acid chemical GO:0001101 222 0.015
neuron apoptotic process GO:0051402 88 0.015
dna metabolic process GO:0006259 96 0.015
positive regulation of ras gtpase activity GO:0032320 28 0.015
regulation of small gtpase mediated signal transduction GO:0051056 48 0.015
cellular macromolecular complex assembly GO:0034622 58 0.015
neurotransmitter transport GO:0006836 42 0.015
positive regulation of catabolic process GO:0009896 78 0.014
Human Fly
organ regeneration GO:0031100 101 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of cell motility GO:2000145 131 0.014
Human
immune effector process GO:0002252 53 0.014
developmental maturation GO:0021700 25 0.014
rho protein signal transduction GO:0007266 11 0.014
cerebellar purkinje cell layer development GO:0021680 2 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
axon choice point recognition GO:0016198 2 0.014
regulation of protein localization GO:0032880 81 0.014
Human
stress activated mapk cascade GO:0051403 35 0.014
regulation of ras gtpase activity GO:0032318 32 0.014
signal release GO:0023061 145 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
activation of mapkkk activity GO:0000185 1 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
single organism reproductive process GO:0044702 297 0.014
Fly
cellular response to endogenous stimulus GO:0071495 377 0.013
establishment of protein localization GO:0045184 141 0.013
Fly
stress activated protein kinase signaling cascade GO:0031098 37 0.013
ensheathment of neurons GO:0007272 40 0.013
cellular response to starvation GO:0009267 27 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
positive regulation of synaptic transmission GO:0050806 62 0.013
immune response GO:0006955 104 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
protein polymerization GO:0051258 22 0.013
chromosome segregation GO:0007059 2 0.013
Human
regulation of cellular component biogenesis GO:0044087 86 0.013
Human Fly
regulation of nucleoside metabolic process GO:0009118 66 0.013
regulation of ras protein signal transduction GO:0046578 45 0.013
response to amine GO:0014075 46 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
response to reactive oxygen species GO:0000302 120 0.013
dendritic spine development GO:0060996 20 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
dna integrity checkpoint GO:0031570 2 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
vesicle docking involved in exocytosis GO:0006904 4 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
negative regulation of gene expression GO:0010629 199 0.013
Human
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.013
metal ion transport GO:0030001 289 0.013
kidney development GO:0001822 67 0.013
regulation of immune system process GO:0002682 123 0.012
rhythmic process GO:0048511 156 0.012
regulation of cell growth GO:0001558 85 0.012
collateral sprouting GO:0048668 2 0.012
reproductive process GO:0022414 372 0.012
Fly
response to extracellular stimulus GO:0009991 380 0.012
morphogenesis of embryonic epithelium GO:0016331 3 0.012
axon midline choice point recognition GO:0016199 2 0.012
cellular protein localization GO:0034613 122 0.012
Human Fly
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
olfactory behavior GO:0042048 2 0.012
protein homooligomerization GO:0051260 91 0.012
tissue development GO:0009888 252 0.012
peptidyl serine phosphorylation GO:0018105 33 0.012
response to oxidative stress GO:0006979 186 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
localization of cell GO:0051674 202 0.012
Human Fly
cellular response to organonitrogen compound GO:0071417 197 0.012
actin filament based process GO:0030029 86 0.011
Fly
negative regulation of signaling GO:0023057 157 0.011
Human Fly
hormone secretion GO:0046879 115 0.011
detection of visible light GO:0009584 3 0.011
p38mapk cascade GO:0038066 1 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.011
multicellular organism reproduction GO:0032504 233 0.011
Fly
positive regulation of rna metabolic process GO:0051254 203 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
Human
urogenital system development GO:0001655 78 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
carboxylic acid transport GO:0046942 115 0.011
regulation of rab gtpase activity GO:0032313 3 0.011
response to temperature stimulus GO:0009266 94 0.011
macromolecule localization GO:0033036 252 0.011
Human Fly
jnk cascade GO:0007254 28 0.011
vesicle localization GO:0051648 33 0.011
appendage morphogenesis GO:0035107 4 0.011
heart morphogenesis GO:0003007 3 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
regulation of growth GO:0040008 105 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of dna metabolic process GO:0051052 60 0.011
synaptic transmission glutamatergic GO:0035249 33 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
Fly
forebrain development GO:0030900 98 0.011
response to alkaloid GO:0043279 132 0.011
cellular response to nutrient levels GO:0031669 60 0.011
receptor internalization GO:0031623 14 0.011
regulation of cellular component size GO:0032535 51 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of protein complex assembly GO:0043254 33 0.011
Fly
taxis GO:0042330 67 0.011
Fly
multicellular organismal signaling GO:0035637 44 0.010
regulation of anion transport GO:0044070 43 0.010
cellular response to peptide GO:1901653 133 0.010
cellular response to lipid GO:0071396 201 0.010
regulation of cell maturation GO:1903429 3 0.010
response to decreased oxygen levels GO:0036293 237 0.010
adult locomotory behavior GO:0008344 4 0.010
eye morphogenesis GO:0048592 4 0.010
Fly
regulation of cell morphogenesis GO:0022604 77 0.010
regulation of behavior GO:0050795 61 0.010
response to wounding GO:0009611 254 0.010
cell communication involved in cardiac conduction GO:0086065 2 0.010
regeneration GO:0031099 163 0.010
regulation of catabolic process GO:0009894 113 0.010
Human Fly
regulation of neuron death GO:1901214 115 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
Human
development of primary sexual characteristics GO:0045137 107 0.010
negative regulation of developmental process GO:0051093 125 0.010
Fly
amide transport GO:0042886 105 0.010

Apc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.055
Human
disease of cellular proliferation DOID:14566 0 0.055
Human
colon carcinoma DOID:1520 0 0.017
Human
large intestine cancer DOID:5672 0 0.017
Human
colon cancer DOID:219 0 0.017
Human
gastrointestinal system cancer DOID:3119 0 0.017
Human
intestinal cancer DOID:10155 0 0.017
Human
organ system cancer DOID:0050686 0 0.017
Human
colorectal cancer DOID:9256 0 0.017
Human
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.012