Rattus norvegicus

12 known processes

Abcb4

ATP-binding cassette, subfamily B (MDR/TAP), member 4

(Aliases: Pgy3,Mdr2)

Abcb4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.480
Rat Worm
response to other organism GO:0051707 220 0.404
Worm
lipid localization GO:0010876 62 0.351
Worm
regulation of transcription dna templated GO:0006355 374 0.291
regulation of rna metabolic process GO:0051252 391 0.286
rna biosynthetic process GO:0032774 380 0.281
regulation of intracellular signal transduction GO:1902531 218 0.265
intracellular signal transduction GO:0035556 314 0.260
transcription dna templated GO:0006351 377 0.248
cellular response to oxygen containing compound GO:1901701 386 0.243
Rat
tissue development GO:0009888 252 0.232
Rat
rna metabolic process GO:0016070 406 0.218
negative regulation of metabolic process GO:0009892 331 0.215
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.208
regulation of rna biosynthetic process GO:2001141 381 0.205
lipid transport GO:0006869 61 0.202
response to carbohydrate GO:0009743 183 0.198
response to peptide GO:1901652 292 0.194
cellular response to endogenous stimulus GO:0071495 377 0.187
Rat
macromolecule localization GO:0033036 252 0.184
Worm
negative regulation of rna metabolic process GO:0051253 123 0.176
response to glucocorticoid GO:0051384 223 0.176
negative regulation of macromolecule metabolic process GO:0010605 260 0.172
response to nutrient levels GO:0031667 370 0.162
Rat
response to oxygen levels GO:0070482 265 0.161
Rat Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.159
lipid metabolic process GO:0006629 283 0.158
secretion GO:0046903 307 0.156
Rat
carboxylic acid metabolic process GO:0019752 289 0.147
negative regulation of cellular metabolic process GO:0031324 281 0.130
cellular response to insulin stimulus GO:0032869 81 0.128
regulation of multicellular organismal development GO:2000026 376 0.125
organic acid transport GO:0015849 116 0.124
cellular response to nitrogen compound GO:1901699 210 0.123
Rat
neuron projection development GO:0031175 273 0.122
monocarboxylic acid transport GO:0015718 52 0.113
single organism biosynthetic process GO:0044711 342 0.110
response to external biotic stimulus GO:0043207 221 0.105
Worm
positive regulation of cellular biosynthetic process GO:0031328 295 0.105
negative regulation of nucleic acid templated transcription GO:1903507 117 0.104
negative regulation of biosynthetic process GO:0009890 168 0.102
response to extracellular stimulus GO:0009991 380 0.101
Rat
oxoacid metabolic process GO:0043436 290 0.101
homeostatic process GO:0042592 331 0.100
negative regulation of transcription dna templated GO:0045892 116 0.098
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.096
cellular response to stress GO:0033554 269 0.095
Rat
cellular response to peptide GO:1901653 133 0.094
organic anion transport GO:0015711 132 0.093
monocarboxylic acid metabolic process GO:0032787 152 0.091
glycoside transport GO:1901656 2 0.090
Rat
nitrogen compound transport GO:0071705 229 0.090
Yeast Rat
positive regulation of developmental process GO:0051094 283 0.089
steroid metabolic process GO:0008202 73 0.088
cellular response to hormone stimulus GO:0032870 247 0.086
Rat
catabolic process GO:0009056 351 0.084
Yeast Fly
negative regulation of cell death GO:0060548 229 0.083
Rat
negative regulation of gene expression GO:0010629 199 0.083
cellular response to organonitrogen compound GO:0071417 197 0.083
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.082
cellular lipid metabolic process GO:0044255 208 0.080
organic acid metabolic process GO:0006082 292 0.079
negative regulation of cellular biosynthetic process GO:0031327 161 0.078
response to corticosteroid GO:0031960 235 0.078
response to transition metal nanoparticle GO:1990267 122 0.077
regulation of phosphate metabolic process GO:0019220 349 0.077
reproductive system development GO:0061458 128 0.074
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.072
programmed cell death GO:0012501 392 0.072
reproductive structure development GO:0048608 128 0.071
Rat
response to molecule of bacterial origin GO:0002237 194 0.071
reactive oxygen species metabolic process GO:0072593 37 0.071
reproductive process GO:0022414 372 0.071
Rat Fly
negative regulation of multicellular organismal process GO:0051241 203 0.070
smooth muscle cell proliferation GO:0048659 77 0.070
chemical homeostasis GO:0048878 292 0.070
regulation of anatomical structure morphogenesis GO:0022603 141 0.069
positive regulation of immune system process GO:0002684 90 0.068
cation transport GO:0006812 382 0.067
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.067
response to ketone GO:1901654 182 0.066
Rat
aging GO:0007568 241 0.066
cellular catabolic process GO:0044248 295 0.065
Yeast Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.065
carboxylic acid transport GO:0046942 115 0.065
negative regulation of response to stimulus GO:0048585 155 0.065
positive regulation of transcription dna templated GO:0045893 197 0.063
positive regulation of rna biosynthetic process GO:1902680 197 0.063
regulation of secretion GO:0051046 224 0.062
neuron differentiation GO:0030182 368 0.062
transcription from rna polymerase ii promoter GO:0006366 252 0.062
response to peptide hormone GO:0043434 278 0.062
anatomical structure morphogenesis GO:0009653 298 0.062
cellular response to glucocorticoid stimulus GO:0071385 68 0.062
Rat
cellular amide metabolic process GO:0043603 44 0.062
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.061
apoptotic process GO:0006915 381 0.061
organonitrogen compound biosynthetic process GO:1901566 167 0.061
positive regulation of signaling GO:0023056 270 0.059
single organism reproductive process GO:0044702 297 0.058
Rat Fly
small molecule biosynthetic process GO:0044283 124 0.058
cellular response to peptide hormone stimulus GO:0071375 120 0.057
regulation of signal transduction GO:0009966 318 0.057
nucleic acid templated transcription GO:0097659 379 0.057
negative regulation of rna biosynthetic process GO:1902679 118 0.056
cellular response to lipid GO:0071396 201 0.055
Rat
secretion by cell GO:0032940 248 0.055
cellular response to external stimulus GO:0071496 118 0.055
positive regulation of cell communication GO:0010647 271 0.054
positive regulation of nucleic acid templated transcription GO:1903508 197 0.054
regulation of secretion by cell GO:1903530 208 0.054
positive regulation of biosynthetic process GO:0009891 319 0.053
positive regulation of locomotion GO:0040017 102 0.053
positive regulation of signal transduction GO:0009967 175 0.053
immune system process GO:0002376 204 0.052
Worm
myelination GO:0042552 39 0.052
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.051
regulation of body fluid levels GO:0050878 90 0.051
Rat
response to camp GO:0051591 91 0.050
gland development GO:0048732 155 0.050
Rat
organ formation GO:0048645 3 0.050
regulation of protein metabolic process GO:0051246 289 0.050
response to vitamin GO:0033273 131 0.050
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.048
regulation of apoptotic process GO:0042981 335 0.047
placenta development GO:0001890 22 0.047
Rat
transmembrane transport GO:0055085 412 0.046
Yeast Rat Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.046
response to wounding GO:0009611 254 0.046
response to cytokine GO:0034097 215 0.045
Rat
response to estradiol GO:0032355 164 0.045
Rat
muscle structure development GO:0061061 87 0.045
bile acid and bile salt transport GO:0015721 12 0.045
regulation of molecular function GO:0065009 398 0.045
b cell differentiation GO:0030183 2 0.044
regeneration GO:0031099 163 0.044
response to hypoxia GO:0001666 231 0.044
Rat Fly
single organism catabolic process GO:0044712 283 0.043
Yeast Fly
regulation of cell proliferation GO:0042127 359 0.043
regulation of cellular localization GO:0060341 263 0.042
regulation of cellular amino acid metabolic process GO:0006521 2 0.042
cellular component movement GO:0006928 248 0.042
Fly
response to biotic stimulus GO:0009607 226 0.042
Worm
cellular component biogenesis GO:0044085 368 0.042
regulation of programmed cell death GO:0043067 341 0.042
amide transport GO:0042886 105 0.042
Yeast
anion transport GO:0006820 178 0.042
positive regulation of intracellular signal transduction GO:1902533 138 0.041
positive regulation of cell migration GO:0030335 96 0.041
neuronal action potential GO:0019228 35 0.041
macromolecular complex assembly GO:0065003 273 0.041
regulation of locomotion GO:0040012 148 0.040
regulation of response to stress GO:0080134 126 0.039
multicellular organismal signaling GO:0035637 44 0.039
cellular response to steroid hormone stimulus GO:0071383 93 0.038
Rat
negative regulation of programmed cell death GO:0043069 183 0.038
lipid biosynthetic process GO:0008610 128 0.037
organophosphate metabolic process GO:0019637 370 0.037
Yeast Fly
liver development GO:0001889 90 0.037
response to growth factor GO:0070848 189 0.037
regulation of reactive oxygen species metabolic process GO:2000377 26 0.037
fatty acid metabolic process GO:0006631 99 0.037
mapk cascade GO:0000165 140 0.036
ensheathment of neurons GO:0007272 40 0.036
organic hydroxy compound transport GO:0015850 77 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
Rat
cellular ketone metabolic process GO:0042180 51 0.035
anatomical structure formation involved in morphogenesis GO:0048646 83 0.035
cellular component morphogenesis GO:0032989 155 0.035
muscle tissue development GO:0060537 58 0.035
cellular component assembly GO:0022607 360 0.035
cellular chemical homeostasis GO:0055082 247 0.035
response to estrogen GO:0043627 232 0.035
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.034
response to hexose GO:0009746 144 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
Fly
regulation of immune response GO:0050776 55 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.034
axon ensheathment GO:0008366 40 0.034
locomotion GO:0040011 237 0.034
Fly
regulation of immune system process GO:0002682 123 0.033
multicellular organism reproduction GO:0032504 233 0.033
Fly
organic acid biosynthetic process GO:0016053 83 0.033
head development GO:0060322 247 0.033
regulation of neuron differentiation GO:0045664 208 0.033
negative regulation of developmental process GO:0051093 125 0.033
positive regulation of phosphorylation GO:0042327 177 0.033
response to ethanol GO:0045471 162 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.032
brain development GO:0007420 247 0.031
glucose metabolic process GO:0006006 52 0.031
positive regulation of gene expression GO:0010628 244 0.031
regulation of catalytic activity GO:0050790 304 0.031
regulation of mapk cascade GO:0043408 116 0.030
regulation of immunoglobulin production GO:0002637 4 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
cytokine mediated signaling pathway GO:0019221 43 0.030
response to nutrient GO:0007584 248 0.030
Rat
transmission of nerve impulse GO:0019226 42 0.029
hexose metabolic process GO:0019318 58 0.029
signal transduction by phosphorylation GO:0023014 144 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
negative regulation of cardiac muscle tissue development GO:0055026 3 0.029
muscle cell proliferation GO:0033002 84 0.029
negative regulation of cell differentiation GO:0045596 99 0.029
organic substance catabolic process GO:1901575 316 0.029
Yeast Fly
regulation of dna metabolic process GO:0051052 60 0.029
neuron death GO:0070997 127 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.028
gliogenesis GO:0042063 93 0.028
Fly
protein complex assembly GO:0006461 263 0.028
single organism carbohydrate metabolic process GO:0044723 118 0.028
regulation of jnk cascade GO:0046328 19 0.028
positive regulation of cellular component movement GO:0051272 102 0.028
response to glucose GO:0009749 136 0.028
positive regulation of immune response GO:0050778 42 0.027
peptidyl tyrosine phosphorylation GO:0018108 72 0.027
response to lipopolysaccharide GO:0032496 191 0.027
dna metabolic process GO:0006259 96 0.027
regulation of neuron death GO:1901214 115 0.026
cholesterol homeostasis GO:0042632 3 0.026
cellular response to organic cyclic compound GO:0071407 202 0.026
Rat
cellular protein localization GO:0034613 122 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
intracellular transport GO:0046907 185 0.025
cellular homeostasis GO:0019725 252 0.025
negative regulation of molecular function GO:0044092 133 0.025
dendrite development GO:0016358 72 0.025
cellular response to nutrient levels GO:0031669 60 0.025
carboxylic acid biosynthetic process GO:0046394 83 0.025
response to monosaccharide GO:0034284 159 0.025
response to purine containing compound GO:0014074 126 0.025
cell projection organization GO:0030030 302 0.025
cell communication by chemical coupling GO:0010643 2 0.024
innate immune response GO:0045087 35 0.024
Worm
negative regulation of epithelial cell proliferation GO:0050680 16 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
regulation of nervous system development GO:0051960 264 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
axon development GO:0061564 96 0.024
activation of immune response GO:0002253 26 0.023
circulatory system process GO:0003013 183 0.023
regulation of cell development GO:0060284 263 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
cellular response to corticosteroid stimulus GO:0071384 69 0.023
Rat
response to insulin GO:0032868 133 0.023
blood circulation GO:0008015 183 0.023
response to metal ion GO:0010038 253 0.023
Rat Worm
heterocycle catabolic process GO:0046700 167 0.023
Yeast Fly
regulation of erk1 and erk2 cascade GO:0070372 41 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
cell cell signaling GO:0007267 335 0.022
stress activated mapk cascade GO:0051403 35 0.022
monosaccharide metabolic process GO:0005996 61 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.022
immune system development GO:0002520 41 0.022
dephosphorylation GO:0016311 98 0.022
protein oligomerization GO:0051259 191 0.022
biological adhesion GO:0022610 110 0.022
cellular response to dexamethasone stimulus GO:0071549 36 0.022
Rat
gonad development GO:0008406 104 0.022
purine containing compound metabolic process GO:0072521 253 0.022
Yeast Fly
hepaticobiliary system development GO:0061008 90 0.021
carbohydrate biosynthetic process GO:0016051 42 0.021
arachidonic acid metabolic process GO:0019369 20 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
cellular amine metabolic process GO:0044106 38 0.020
lymphocyte activation involved in immune response GO:0002285 3 0.020
peptidyl tyrosine modification GO:0018212 72 0.020
response to decreased oxygen levels GO:0036293 237 0.020
Rat Fly
cell morphogenesis GO:0000902 142 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
positive regulation of mapk cascade GO:0043410 92 0.020
vesicle mediated transport GO:0016192 181 0.020
wound healing GO:0042060 122 0.020
organic cation transport GO:0015695 11 0.020
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
Yeast Fly
cellular calcium ion homeostasis GO:0006874 160 0.020
amino acid transport GO:0006865 70 0.019
embryo development GO:0009790 49 0.019
Worm
nucleotide metabolic process GO:0009117 279 0.019
Yeast Fly
regulation of neuron projection development GO:0010975 161 0.019
glucose homeostasis GO:0042593 75 0.019
regulation of hormone levels GO:0010817 187 0.019
Yeast Rat
neuron development GO:0048666 286 0.019
female pregnancy GO:0007565 122 0.019
proteolysis GO:0006508 175 0.019
reproduction GO:0000003 245 0.019
Fly
organelle organization GO:0006996 266 0.019
Worm
renal system development GO:0072001 67 0.019
positive regulation of molecular function GO:0044093 230 0.019
response to starvation GO:0042594 59 0.019
single organism intracellular transport GO:1902582 166 0.018
stress activated protein kinase signaling cascade GO:0031098 37 0.018
amine metabolic process GO:0009308 38 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
sterol homeostasis GO:0055092 3 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
positive regulation of cell development GO:0010720 176 0.018
response to toxic substance GO:0009636 133 0.018
Rat
positive regulation of transport GO:0051050 245 0.018
bile acid secretion GO:0032782 5 0.018
regulation of catabolic process GO:0009894 113 0.018
negative regulation of neuron death GO:1901215 69 0.018
cellular response to molecule of bacterial origin GO:0071219 56 0.018
cellular response to alcohol GO:0097306 87 0.018
Rat
negative regulation of signal transduction GO:0009968 83 0.018
ras protein signal transduction GO:0007265 29 0.018
protein complex subunit organization GO:0071822 302 0.017
sulfur compound metabolic process GO:0006790 70 0.017
peptide transport GO:0015833 97 0.017
Yeast
regulation of response to external stimulus GO:0032101 106 0.017
circulatory system development GO:0072359 134 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
epithelial cell proliferation GO:0050673 54 0.017
aromatic compound catabolic process GO:0019439 168 0.017
Yeast Fly
regulation of cellular protein metabolic process GO:0032268 267 0.017
regulation of growth GO:0040008 105 0.017
hepatocyte differentiation GO:0070365 8 0.017
growth GO:0040007 165 0.017
carbohydrate metabolic process GO:0005975 130 0.017
canalicular bile acid transport GO:0015722 5 0.017
regulation of homeostatic process GO:0032844 101 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
Yeast Fly
regulation of cell motility GO:2000145 131 0.016
response to bacterium GO:0009617 200 0.016
Worm
negative regulation of protein metabolic process GO:0051248 114 0.016
positive regulation of blood coagulation GO:0030194 4 0.016
positive regulation of isotype switching GO:0045830 1 0.016
regulation of system process GO:0044057 208 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
developmental process involved in reproduction GO:0003006 159 0.016
Rat
response to interleukin 15 GO:0070672 4 0.016
erythrocyte differentiation GO:0030218 1 0.016
cellular response to oxidative stress GO:0034599 76 0.016
response to oxidative stress GO:0006979 186 0.016
tube development GO:0035295 89 0.016
single organism cellular localization GO:1902580 102 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
regulation of b cell differentiation GO:0045577 1 0.015
purine nucleoside monophosphate catabolic process GO:0009128 55 0.015
Yeast Fly
multi organism reproductive process GO:0044703 262 0.015
Fly
cellular cation homeostasis GO:0030003 180 0.015
localization of cell GO:0051674 202 0.015
Fly
positive regulation of cell projection organization GO:0031346 111 0.015
kidney development GO:0001822 67 0.015
regulation of protein localization GO:0032880 81 0.015
action potential GO:0001508 54 0.015
response to radiation GO:0009314 137 0.015
Rat
macromolecule catabolic process GO:0009057 58 0.015
cytoplasmic transport GO:0016482 115 0.015
protein transport GO:0015031 132 0.014
regulation of cellular component organization GO:0051128 368 0.014
regulation of membrane potential GO:0042391 110 0.014
sex differentiation GO:0007548 113 0.014
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.014
endocytosis GO:0006897 84 0.014
positive regulation of cell death GO:0010942 184 0.014
response to retinoic acid GO:0032526 63 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.014
cell adhesion GO:0007155 110 0.014
taxis GO:0042330 67 0.014
gastrulation GO:0007369 2 0.014
protein localization GO:0008104 191 0.014
connective tissue development GO:0061448 33 0.014
positive regulation of catabolic process GO:0009896 78 0.014
single organism membrane organization GO:0044802 74 0.014
response to mechanical stimulus GO:0009612 134 0.014
cellular macromolecule localization GO:0070727 122 0.014
cell fate determination GO:0001709 2 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
Yeast Fly
jnk cascade GO:0007254 28 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.014
regulation of neurogenesis GO:0050767 247 0.014
central nervous system development GO:0007417 311 0.013
Rat
negative regulation of protein maturation GO:1903318 47 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
regulation of cell cycle g2 m phase transition GO:1902749 4 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of immunoglobulin secretion GO:0051023 1 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
defense response GO:0006952 194 0.013
Worm
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.013
cell projection morphogenesis GO:0048858 123 0.013
muscle cell differentiation GO:0042692 52 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
regulation of insulin secretion GO:0050796 65 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
Yeast Fly
regulation of defense response GO:0031347 68 0.013
heart development GO:0007507 72 0.013
neuron projection morphogenesis GO:0048812 122 0.013
multi multicellular organism process GO:0044706 138 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
peptide hormone secretion GO:0030072 84 0.013
linoleic acid metabolic process GO:0043651 4 0.013
digestive system development GO:0055123 41 0.013
metanephric epithelium development GO:0072207 4 0.013
negative regulation of cell communication GO:0010648 158 0.012
organ induction GO:0001759 1 0.012
single organism organelle organization GO:1902589 180 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
Yeast Fly
protein complex biogenesis GO:0070271 263 0.012
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.012
developmental induction GO:0031128 2 0.012
negative regulation of signaling GO:0023057 157 0.012
inflammatory response GO:0006954 150 0.012
negative regulation of transport GO:0051051 136 0.012
response to tumor necrosis factor GO:0034612 56 0.012
Rat
regulation of protein transport GO:0051223 68 0.012
blood coagulation GO:0007596 26 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
salivary gland development GO:0007431 3 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
negative regulation of phosphorylation GO:0042326 57 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
negative regulation of mapk cascade GO:0043409 20 0.012
regulation of organ morphogenesis GO:2000027 22 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
muscle organ development GO:0007517 50 0.012
regulation of hydrolase activity GO:0051336 143 0.012
negative regulation of immune system process GO:0002683 39 0.012
coagulation GO:0050817 28 0.012
response to fluid shear stress GO:0034405 16 0.011
response to amino acid GO:0043200 75 0.011
Rat
regulation of muscle organ development GO:0048634 26 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
eye development GO:0001654 50 0.011
regulation of kinase activity GO:0043549 117 0.011
nuclear transport GO:0051169 49 0.011
long chain fatty acid metabolic process GO:0001676 32 0.011
peptide metabolic process GO:0006518 32 0.011
spermatogenesis GO:0007283 99 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
neurological system process GO:0050877 219 0.011
organ regeneration GO:0031100 101 0.011
regulation of cell differentiation GO:0045595 320 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
amino acid transmembrane transport GO:0003333 33 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
Yeast Fly
phospholipid efflux GO:0033700 1 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
Yeast Fly
negative regulation of humoral immune response GO:0002921 4 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
Yeast Fly
purine nucleotide metabolic process GO:0006163 229 0.011
Yeast Fly
gamete generation GO:0007276 124 0.011
Fly
lipid storage GO:0019915 1 0.011
Worm
glycerolipid metabolic process GO:0046486 67 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
Worm
axis specification GO:0009798 4 0.011
skeletal muscle tissue development GO:0007519 31 0.011
hexose transport GO:0008645 29 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
Rat
response to vitamin d GO:0033280 34 0.011
Rat
cell cycle checkpoint GO:0000075 2 0.011
ribonucleotide metabolic process GO:0009259 231 0.010
Yeast Fly
alpha beta t cell activation GO:0046631 3 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
Yeast Fly
regulation of cell projection organization GO:0031344 175 0.010
regulation of isotype switching GO:0045191 1 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
peptidyl amino acid modification GO:0018193 126 0.010
urogenital system development GO:0001655 78 0.010
signal release GO:0023061 145 0.010
cellular ion homeostasis GO:0006873 184 0.010
positive regulation of cell motility GO:2000147 97 0.010
interleukin 12 production GO:0032615 3 0.010
regulation of cell migration GO:0030334 128 0.010

Abcb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
Human
nervous system disease DOID:863 0 0.027
central nervous system disease DOID:331 0 0.020
disease of metabolism DOID:0014667 0 0.019
disease of cellular proliferation DOID:14566 0 0.016
vascular disease DOID:178 0 0.014
cardiovascular system disease DOID:1287 0 0.014
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
gastrointestinal system disease DOID:77 0 0.010
Human