Rattus norvegicus

42 known processes

Ephx2

epoxide hydrolase 2, cytoplasmic

Ephx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 152 0.686
carboxylic acid metabolic process GO:0019752 289 0.553
organic acid metabolic process GO:0006082 292 0.463
lipid metabolic process GO:0006629 283 0.438
oxoacid metabolic process GO:0043436 290 0.402
cellular lipid metabolic process GO:0044255 208 0.296
fatty acid metabolic process GO:0006631 99 0.279
oxidation reduction process GO:0055114 304 0.268
catabolic process GO:0009056 351 0.244
fatty acid catabolic process GO:0009062 26 0.227
organic substance catabolic process GO:1901575 316 0.211
small molecule catabolic process GO:0044282 59 0.206
response to nutrient levels GO:0031667 370 0.196
cellular catabolic process GO:0044248 295 0.193
fatty acid beta oxidation GO:0006635 22 0.192
carboxylic acid catabolic process GO:0046395 49 0.184
organic acid catabolic process GO:0016054 49 0.171
lipid catabolic process GO:0016042 46 0.149
response to peptide hormone GO:0043434 278 0.145
single organism catabolic process GO:0044712 283 0.140
cellular response to hormone stimulus GO:0032870 247 0.134
lipid oxidation GO:0034440 30 0.128
cellular response to peptide hormone stimulus GO:0071375 120 0.124
response to extracellular stimulus GO:0009991 380 0.122
cellular response to peptide GO:1901653 133 0.102
regulation of hormone levels GO:0010817 187 0.094
response to nutrient GO:0007584 248 0.086
fatty acid oxidation GO:0019395 29 0.083
cellular ketone metabolic process GO:0042180 51 0.082
monocarboxylic acid catabolic process GO:0072329 28 0.082
response to peptide GO:1901652 292 0.080
cellular response to endogenous stimulus GO:0071495 377 0.073
cellular response to lipid GO:0071396 201 0.072
response to biotic stimulus GO:0009607 226 0.069
response to insulin GO:0032868 133 0.069
cellular lipid catabolic process GO:0044242 37 0.069
positive regulation of response to stimulus GO:0048584 285 0.066
response to lipopolysaccharide GO:0032496 191 0.066
gland development GO:0048732 155 0.063
regulation of apoptotic process GO:0042981 335 0.058
central nervous system development GO:0007417 311 0.055
regulation of signal transduction GO:0009966 318 0.053
response to other organism GO:0051707 220 0.053
regulation of programmed cell death GO:0043067 341 0.052
organ regeneration GO:0031100 101 0.050
organic hydroxy compound metabolic process GO:1901615 115 0.050
cellular response to insulin stimulus GO:0032869 81 0.050
steroid metabolic process GO:0008202 73 0.049
programmed cell death GO:0012501 392 0.048
cellular component biogenesis GO:0044085 368 0.048
reproductive system development GO:0061458 128 0.048
regulation of protein metabolic process GO:0051246 289 0.047
response to acid chemical GO:0001101 222 0.047
reproductive process GO:0022414 372 0.047
regeneration GO:0031099 163 0.045
positive regulation of cell communication GO:0010647 271 0.044
response to corticosteroid GO:0031960 235 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
cofactor metabolic process GO:0051186 95 0.043
response to external biotic stimulus GO:0043207 221 0.043
macromolecular complex assembly GO:0065003 273 0.042
aging GO:0007568 241 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
single organism biosynthetic process GO:0044711 342 0.041
regulation of molecular function GO:0065009 398 0.041
head development GO:0060322 247 0.040
response to glucocorticoid GO:0051384 223 0.040
monosaccharide metabolic process GO:0005996 61 0.040
rna metabolic process GO:0016070 406 0.040
liver development GO:0001889 90 0.039
coenzyme metabolic process GO:0006732 86 0.039
response to ethanol GO:0045471 162 0.038
macromolecular complex subunit organization GO:0043933 339 0.038
protein complex assembly GO:0006461 263 0.037
developmental process involved in reproduction GO:0003006 159 0.037
regulation of catalytic activity GO:0050790 304 0.037
regulation of rna metabolic process GO:0051252 391 0.037
cellular response to nitrogen compound GO:1901699 210 0.037
cellular component assembly GO:0022607 360 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
response to estrogen GO:0043627 232 0.036
single organism reproductive process GO:0044702 297 0.036
lipid modification GO:0030258 52 0.035
organophosphate metabolic process GO:0019637 370 0.035
response to molecule of bacterial origin GO:0002237 194 0.035
small molecule biosynthetic process GO:0044283 124 0.034
response to inorganic substance GO:0010035 377 0.034
rna biosynthetic process GO:0032774 380 0.033
regulation of multicellular organismal development GO:2000026 376 0.031
response to growth factor GO:0070848 189 0.031
protein oligomerization GO:0051259 191 0.031
positive regulation of molecular function GO:0044093 230 0.031
neuron projection development GO:0031175 273 0.030
regulation of cell proliferation GO:0042127 359 0.030
regulation of transcription dna templated GO:0006355 374 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
neuron differentiation GO:0030182 368 0.030
hepaticobiliary system development GO:0061008 90 0.029
response to carbohydrate GO:0009743 183 0.029
multi organism reproductive process GO:0044703 262 0.029
response to radiation GO:0009314 137 0.029
protein phosphorylation GO:0006468 345 0.029
response to metal ion GO:0010038 253 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
regulation of rna biosynthetic process GO:2001141 381 0.028
heterocycle catabolic process GO:0046700 167 0.028
regulation of lipid metabolic process GO:0019216 68 0.028
response to toxic substance GO:0009636 133 0.028
cellular hormone metabolic process GO:0034754 49 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
positive regulation of signaling GO:0023056 270 0.026
regulation of cell differentiation GO:0045595 320 0.026
protein complex subunit organization GO:0071822 302 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
reproduction GO:0000003 245 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
multicellular organism reproduction GO:0032504 233 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
regulation of cell development GO:0060284 263 0.025
cellular response to stress GO:0033554 269 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
response to bacterium GO:0009617 200 0.025
nucleic acid templated transcription GO:0097659 379 0.025
organic acid biosynthetic process GO:0016053 83 0.025
negative regulation of metabolic process GO:0009892 331 0.025
hormone metabolic process GO:0042445 69 0.025
cell projection organization GO:0030030 302 0.025
retinal metabolic process GO:0042574 3 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
negative regulation of apoptotic process GO:0043066 181 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
apoptotic process GO:0006915 381 0.024
cellular amine metabolic process GO:0044106 38 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
lipid localization GO:0010876 62 0.023
negative regulation of cell death GO:0060548 229 0.023
thioester metabolic process GO:0035383 28 0.023
response to ketone GO:1901654 182 0.023
protein transport GO:0015031 132 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
positive regulation of signal transduction GO:0009967 175 0.023
homeostatic process GO:0042592 331 0.023
amine metabolic process GO:0009308 38 0.023
carnitine metabolic process GO:0009437 3 0.023
chlorinated hydrocarbon metabolic process GO:0042196 4 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
amide transport GO:0042886 105 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
neuron development GO:0048666 286 0.022
brain development GO:0007420 247 0.022
reproductive structure development GO:0048608 128 0.022
regulation of phosphorylation GO:0042325 248 0.022
response to xenobiotic stimulus GO:0009410 23 0.022
lipid biosynthetic process GO:0008610 128 0.021
secretion GO:0046903 307 0.021
response to vitamin GO:0033273 131 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
vesicle mediated transport GO:0016192 181 0.021
regulation of neurogenesis GO:0050767 247 0.021
signal release GO:0023061 145 0.021
regulation of secretion by cell GO:1903530 208 0.021
intracellular signal transduction GO:0035556 314 0.021
regulation of nervous system development GO:0051960 264 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
aromatic compound catabolic process GO:0019439 168 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
long chain fatty acid metabolic process GO:0001676 32 0.021
positive regulation of cell proliferation GO:0008284 249 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
carbohydrate metabolic process GO:0005975 130 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
halogenated hydrocarbon metabolic process GO:0042197 4 0.020
transcription dna templated GO:0006351 377 0.020
regulation of protein modification process GO:0031399 194 0.020
glycerolipid metabolic process GO:0046486 67 0.020
gonad development GO:0008406 104 0.020
protein complex biogenesis GO:0070271 263 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
defense response GO:0006952 194 0.019
positive regulation of lipid catabolic process GO:0050996 4 0.019
cofactor biosynthetic process GO:0051188 28 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
cellular component morphogenesis GO:0032989 155 0.019
alcohol metabolic process GO:0006066 77 0.019
organic anion transport GO:0015711 132 0.019
positive regulation of fatty acid beta oxidation GO:0032000 4 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
positive regulation of cell death GO:0010942 184 0.018
cell part morphogenesis GO:0032990 123 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
hormone transport GO:0009914 121 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
development of primary sexual characteristics GO:0045137 107 0.018
cell morphogenesis GO:0000902 142 0.018
cell projection morphogenesis GO:0048858 123 0.018
purine containing compound metabolic process GO:0072521 253 0.018
cellular amino acid metabolic process GO:0006520 107 0.017
regulation of hormone secretion GO:0046883 106 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
negative regulation of developmental process GO:0051093 125 0.017
transmembrane transport GO:0055085 412 0.017
response to hexose GO:0009746 144 0.017
regulation of fatty acid metabolic process GO:0019217 18 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
positive regulation of gene expression GO:0010628 244 0.017
hormone secretion GO:0046879 115 0.017
cellular component movement GO:0006928 248 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
antral ovarian follicle growth GO:0001547 3 0.017
chemical homeostasis GO:0048878 292 0.016
positive regulation of developmental process GO:0051094 283 0.016
tissue development GO:0009888 252 0.016
response to estradiol GO:0032355 164 0.016
carboxylic acid transport GO:0046942 115 0.016
organic acid transport GO:0015849 116 0.016
regulation of lipid biosynthetic process GO:0046890 38 0.016
acylglycerol metabolic process GO:0006639 21 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
male sex differentiation GO:0046661 64 0.016
response to retinoic acid GO:0032526 63 0.016
lipid transport GO:0006869 61 0.016
establishment of protein localization GO:0045184 141 0.016
response to oxidative stress GO:0006979 186 0.016
response to monosaccharide GO:0034284 159 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
regulation of cellular localization GO:0060341 263 0.016
response to reactive oxygen species GO:0000302 120 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
growth GO:0040007 165 0.016
regulation of transferase activity GO:0051338 123 0.015
nucleotide metabolic process GO:0009117 279 0.015
male gonad development GO:0008584 59 0.015
response to camp GO:0051591 91 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
negative regulation of cell communication GO:0010648 158 0.015
intracellular transport GO:0046907 185 0.015
response to oxygen levels GO:0070482 265 0.015
response to purine containing compound GO:0014074 126 0.015
peptide transport GO:0015833 97 0.015
cellular response to alcohol GO:0097306 87 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
cellular response to xenobiotic stimulus GO:0071466 19 0.015
negative regulation of molecular function GO:0044092 133 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
sulfur compound metabolic process GO:0006790 70 0.014
female pregnancy GO:0007565 122 0.014
retina morphogenesis in camera type eye GO:0060042 1 0.014
peptide secretion GO:0002790 86 0.014
secretion by cell GO:0032940 248 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
regulation of insulin secretion GO:0050796 65 0.014
organelle organization GO:0006996 266 0.014
acyl coa metabolic process GO:0006637 28 0.014
neuron projection morphogenesis GO:0048812 122 0.014
neuron death GO:0070997 127 0.014
regulation of cell projection organization GO:0031344 175 0.014
macromolecule localization GO:0033036 252 0.014
lipid storage GO:0019915 1 0.014
forebrain development GO:0030900 98 0.014
peptidyl amino acid modification GO:0018193 126 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
positive regulation of cell development GO:0010720 176 0.013
hexose metabolic process GO:0019318 58 0.013
protein homooligomerization GO:0051260 91 0.013
gliogenesis GO:0042063 93 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
amino acid betaine metabolic process GO:0006577 3 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
nitrogen compound transport GO:0071705 229 0.013
negative regulation of signaling GO:0023057 157 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
response to wounding GO:0009611 254 0.013
regulation of secretion GO:0051046 224 0.013
response to testosterone GO:0033574 55 0.013
neurological system process GO:0050877 219 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
response to starvation GO:0042594 59 0.013
regulation of b cell differentiation GO:0045577 1 0.013
dephosphorylation GO:0016311 98 0.013
benzene containing compound metabolic process GO:0042537 22 0.013
anion transport GO:0006820 178 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
response to cytokine GO:0034097 215 0.012
regulation of peptide secretion GO:0002791 82 0.012
monocarboxylic acid biosynthetic process GO:0072330 48 0.012
axis specification GO:0009798 4 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
immune response GO:0006955 104 0.012
regulation of kinase activity GO:0043549 117 0.012
cation transmembrane transport GO:0098655 263 0.012
inflammatory response GO:0006954 150 0.012
monocarboxylic acid transport GO:0015718 52 0.012
cellular response to external stimulus GO:0071496 118 0.012
sequestering of triglyceride GO:0030730 1 0.012
dna metabolic process GO:0006259 96 0.012
positive regulation of protein modification process GO:0031401 142 0.012
fatty acid derivative metabolic process GO:1901568 38 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
cellular response to nutrient levels GO:0031669 60 0.012
maintenance of location GO:0051235 17 0.012
neuron apoptotic process GO:0051402 88 0.012
acetyl coa metabolic process GO:0006084 17 0.012
chemosensory behavior GO:0007635 2 0.012
insulin secretion GO:0030073 69 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
response to glucose GO:0009749 136 0.011
regulation of peptide transport GO:0090087 87 0.011
eye morphogenesis GO:0048592 4 0.011
spindle organization GO:0007051 2 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
immune system process GO:0002376 204 0.011
gamete generation GO:0007276 124 0.011
protein autophosphorylation GO:0046777 66 0.011
regulation of immunoglobulin secretion GO:0051023 1 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
glial cell differentiation GO:0010001 65 0.011
negative regulation of collagen biosynthetic process GO:0032966 4 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
response to organophosphorus GO:0046683 102 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
circulatory system development GO:0072359 134 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
cold acclimation GO:0009631 1 0.011
nucleoside metabolic process GO:0009116 179 0.011
single organism intracellular transport GO:1902582 166 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
negative regulation of organ growth GO:0046621 3 0.011
response to ionizing radiation GO:0010212 59 0.011
regulation of membrane potential GO:0042391 110 0.011
protein localization GO:0008104 191 0.011
b cell differentiation GO:0030183 2 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
positive regulation of catabolic process GO:0009896 78 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
jak stat cascade GO:0007259 26 0.010
heart morphogenesis GO:0003007 3 0.010
male gamete generation GO:0048232 99 0.010
phenylpropanoid catabolic process GO:0046271 3 0.010
xenobiotic metabolic process GO:0006805 19 0.010
peptide hormone secretion GO:0030072 84 0.010
acetate ester biosynthetic process GO:1900620 2 0.010
spermatogenesis GO:0007283 99 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
regulation of mapk cascade GO:0043408 116 0.010
negative regulation of gene expression GO:0010629 199 0.010
response to decreased oxygen levels GO:0036293 237 0.010

Ephx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.033
inherited metabolic disorder DOID:655 0 0.030
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023