Rattus norvegicus

0 known processes

Grina

glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

Grina biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 226 0.405
regulation of hormone levels GO:0010817 187 0.330
regulation of programmed cell death GO:0043067 341 0.235
protein complex assembly GO:0006461 263 0.228
apoptotic process GO:0006915 381 0.226
response to glucose GO:0009749 136 0.175
anatomical structure morphogenesis GO:0009653 298 0.173
cellular lipid metabolic process GO:0044255 208 0.155
regulation of hormone secretion GO:0046883 106 0.138
response to hexose GO:0009746 144 0.132
response to nutrient levels GO:0031667 370 0.132
response to other organism GO:0051707 220 0.130
immune system process GO:0002376 204 0.128
response to extracellular stimulus GO:0009991 380 0.118
cellular response to stress GO:0033554 269 0.117
response to carbohydrate GO:0009743 183 0.115
hepatocyte growth factor receptor signaling pathway GO:0048012 1 0.112
programmed cell death GO:0012501 392 0.108
cellular response to endogenous stimulus GO:0071495 377 0.106
innate immune response GO:0045087 35 0.101
hormone transport GO:0009914 121 0.101
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.100
negative regulation of signaling GO:0023057 157 0.098
homeostatic process GO:0042592 331 0.095
catabolic process GO:0009056 351 0.091
response to external biotic stimulus GO:0043207 221 0.089
insulin secretion GO:0030073 69 0.084
cellular response to biotic stimulus GO:0071216 59 0.084
cellular amide metabolic process GO:0043603 44 0.084
cellular catabolic process GO:0044248 295 0.081
regulation of angiotensin levels in blood GO:0002002 2 0.079
receptor metabolic process GO:0043112 18 0.077
myelination GO:0042552 39 0.077
cellular component biogenesis GO:0044085 368 0.077
response to growth factor GO:0070848 189 0.077
regulation of apoptotic process GO:0042981 335 0.076
regulation of peptide hormone secretion GO:0090276 80 0.075
multicellular organismal signaling GO:0035637 44 0.075
peptide hormone secretion GO:0030072 84 0.074
cellular response to extracellular stimulus GO:0031668 73 0.074
protein complex subunit organization GO:0071822 302 0.072
intracellular protein transport GO:0006886 79 0.071
carboxylic acid metabolic process GO:0019752 289 0.071
cellular response to oxygen containing compound GO:1901701 386 0.070
negative regulation of programmed cell death GO:0043069 183 0.068
cell type specific apoptotic process GO:0097285 134 0.067
vesicle mediated transport GO:0016192 181 0.067
regulation of intracellular signal transduction GO:1902531 218 0.067
negative regulation of cell communication GO:0010648 158 0.066
hormone secretion GO:0046879 115 0.064
cellular response to nitrogen compound GO:1901699 210 0.064
cellular protein localization GO:0034613 122 0.064
protein localization GO:0008104 191 0.062
negative regulation of cell death GO:0060548 229 0.062
protein localization to membrane GO:0072657 36 0.062
response to molecule of bacterial origin GO:0002237 194 0.061
establishment of protein localization GO:0045184 141 0.060
regulation of protein localization GO:0032880 81 0.059
organic acid metabolic process GO:0006082 292 0.058
negative regulation of apoptotic process GO:0043066 181 0.057
response to oxygen levels GO:0070482 265 0.056
anion transport GO:0006820 178 0.055
response to hypoxia GO:0001666 231 0.055
cell cell signaling GO:0007267 335 0.054
neuronal action potential GO:0019228 35 0.053
protein transport GO:0015031 132 0.053
oxoacid metabolic process GO:0043436 290 0.051
protein complex biogenesis GO:0070271 263 0.051
protein oligomerization GO:0051259 191 0.049
response to monosaccharide GO:0034284 159 0.049
single organism intracellular transport GO:1902582 166 0.049
positive regulation of multicellular organismal process GO:0051240 387 0.048
secretion GO:0046903 307 0.046
defense response GO:0006952 194 0.046
protein catabolic process GO:0030163 30 0.044
single organism catabolic process GO:0044712 283 0.044
protein phosphorylation GO:0006468 345 0.044
cellular response to starvation GO:0009267 27 0.043
negative regulation of erk1 and erk2 cascade GO:0070373 9 0.043
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.042
regulation of proteasomal protein catabolic process GO:0061136 4 0.042
regulation of peptide secretion GO:0002791 82 0.042
single organism biosynthetic process GO:0044711 342 0.040
mitotic spindle organization GO:0007052 2 0.040
response to lipopolysaccharide GO:0032496 191 0.039
cellular component assembly GO:0022607 360 0.039
regulation of insulin secretion GO:0050796 65 0.039
cellular response to hormone stimulus GO:0032870 247 0.039
regulation of signal transduction GO:0009966 318 0.039
membrane organization GO:0061024 94 0.039
startle response GO:0001964 2 0.039
regulation of angiotensin metabolic process GO:0060177 3 0.038
nitrogen compound transport GO:0071705 229 0.038
response to starvation GO:0042594 59 0.038
reactive oxygen species metabolic process GO:0072593 37 0.038
single organism membrane organization GO:0044802 74 0.037
chemical homeostasis GO:0048878 292 0.037
monocarboxylic acid transport GO:0015718 52 0.037
store operated calcium entry GO:0002115 2 0.036
response to decreased oxygen levels GO:0036293 237 0.036
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.036
response to metal ion GO:0010038 253 0.036
macromolecular complex assembly GO:0065003 273 0.036
response to alkaloid GO:0043279 132 0.036
negative regulation of gene expression GO:0010629 199 0.035
macromolecule localization GO:0033036 252 0.035
regulation of peptide transport GO:0090087 87 0.035
behavioral response to ethanol GO:0048149 1 0.035
cellular response to organonitrogen compound GO:0071417 197 0.035
regulation of meiotic cell cycle GO:0051445 3 0.034
macromolecule catabolic process GO:0009057 58 0.034
cellular response to external stimulus GO:0071496 118 0.034
multi organism reproductive process GO:0044703 262 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
nucleotide catabolic process GO:0009166 139 0.033
cellular response to growth factor stimulus GO:0071363 162 0.033
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.032
muscle structure development GO:0061061 87 0.032
proteolysis GO:0006508 175 0.032
lipid metabolic process GO:0006629 283 0.032
intracellular transport GO:0046907 185 0.031
reproductive process GO:0022414 372 0.031
response to bacterium GO:0009617 200 0.031
positive regulation of cell communication GO:0010647 271 0.030
endocytosis GO:0006897 84 0.030
monocarboxylic acid metabolic process GO:0032787 152 0.030
gtp catabolic process GO:0006184 71 0.030
regulation of cell differentiation GO:0045595 320 0.030
regulation of response to stress GO:0080134 126 0.029
cellular chemical homeostasis GO:0055082 247 0.029
programmed necrotic cell death GO:0097300 2 0.029
peptide secretion GO:0002790 86 0.028
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
cellular response to lipopolysaccharide GO:0071222 55 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
negative regulation of developmental process GO:0051093 125 0.028
regulation of reactive oxygen species metabolic process GO:2000377 26 0.028
organelle organization GO:0006996 266 0.027
regulation of jun kinase activity GO:0043506 10 0.027
action potential GO:0001508 54 0.027
macroautophagy GO:0016236 4 0.027
multicellular organism reproduction GO:0032504 233 0.027
ensheathment of neurons GO:0007272 40 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.027
cellular response to peptide GO:1901653 133 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
transcription dna templated GO:0006351 377 0.027
autophagy GO:0006914 19 0.027
positive regulation of cellular component organization GO:0051130 200 0.026
organic acid transport GO:0015849 116 0.026
positive regulation of transport GO:0051050 245 0.026
neuron death GO:0070997 127 0.026
aminoglycan biosynthetic process GO:0006023 4 0.025
cellular response to organic cyclic compound GO:0071407 202 0.025
choline transport GO:0015871 4 0.025
positive regulation of protein transport GO:0051222 41 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
cellular response to molecule of bacterial origin GO:0071219 56 0.024
regulation of cellular component organization GO:0051128 368 0.024
regulation of cellular localization GO:0060341 263 0.024
regulation of blood pressure GO:0008217 83 0.024
regulation of cell development GO:0060284 263 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
regulation of protein metabolic process GO:0051246 289 0.024
regulation of membrane potential GO:0042391 110 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
sexual reproduction GO:0019953 148 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
organic substance catabolic process GO:1901575 316 0.023
response to corticosteroid GO:0031960 235 0.023
amino acid transport GO:0006865 70 0.023
positive regulation of peptide hormone secretion GO:0090277 50 0.023
single organism reproductive process GO:0044702 297 0.022
peptide transport GO:0015833 97 0.022
cellular macromolecule localization GO:0070727 122 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
necroptotic process GO:0070266 2 0.021
negative regulation of phosphate metabolic process GO:0045936 80 0.021
localization of cell GO:0051674 202 0.021
regulation of cell maturation GO:1903429 3 0.021
purine containing compound biosynthetic process GO:0072522 85 0.021
negative regulation of response to stimulus GO:0048585 155 0.021
intracellular signal transduction GO:0035556 314 0.021
regulation of mapk cascade GO:0043408 116 0.020
response to oxidative stress GO:0006979 186 0.020
cellular protein complex assembly GO:0043623 44 0.020
transmission of nerve impulse GO:0019226 42 0.020
gamete generation GO:0007276 124 0.020
cellular ketone metabolic process GO:0042180 51 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
amide transport GO:0042886 105 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
cellular response to abiotic stimulus GO:0071214 85 0.020
carbohydrate homeostasis GO:0033500 75 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.019
signal release GO:0023061 145 0.019
lipid storage GO:0019915 1 0.019
positive regulation of signaling GO:0023056 270 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
negative regulation of cellular component organization GO:0051129 83 0.019
actin filament branching GO:0090135 1 0.019
inflammatory response GO:0006954 150 0.019
ras protein signal transduction GO:0007265 29 0.018
negative regulation of nervous system development GO:0051961 79 0.018
autophagic cell death GO:0048102 4 0.018
head development GO:0060322 247 0.018
regulation of fat cell differentiation GO:0045598 3 0.018
regulation of cell proliferation GO:0042127 359 0.018
protein tetramerization GO:0051262 38 0.018
single organism cellular localization GO:1902580 102 0.018
purine containing compound metabolic process GO:0072521 253 0.018
regulation of establishment of protein localization GO:0070201 69 0.018
negative regulation of metabolic process GO:0009892 331 0.018
lipid transport GO:0006869 61 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
cellular response to hexose stimulus GO:0071331 65 0.017
central nervous system development GO:0007417 311 0.017
Rat
negative regulation of cell proliferation GO:0008285 119 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
microtubule anchoring GO:0034453 1 0.017
cellular homeostasis GO:0019725 252 0.017
response to peptide hormone GO:0043434 278 0.017
response to insulin GO:0032868 133 0.017
response to estrogen GO:0043627 232 0.017
cellular response to peptide hormone stimulus GO:0071375 120 0.017
negative regulation of neurogenesis GO:0050768 78 0.016
response to nutrient GO:0007584 248 0.016
protein homooligomerization GO:0051260 91 0.016
nucleic acid templated transcription GO:0097659 379 0.016
negative regulation of mitochondrion organization GO:0010823 2 0.016
response to ammonium ion GO:0060359 71 0.016
vasoconstriction GO:0042310 54 0.016
response to peptide GO:1901652 292 0.016
negative regulation of cell development GO:0010721 82 0.016
nucleotide metabolic process GO:0009117 279 0.016
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.016
regulation of transcription dna templated GO:0006355 374 0.015
regulation of stress activated mapk cascade GO:0032872 23 0.015
regulation of neural precursor cell proliferation GO:2000177 16 0.015
negative regulation of transport GO:0051051 136 0.015
small molecule biosynthetic process GO:0044283 124 0.015
peptide metabolic process GO:0006518 32 0.015
metal ion transport GO:0030001 289 0.015
regulation of synaptic transmission GO:0050804 141 0.015
positive regulation of catabolic process GO:0009896 78 0.015
positive regulation of insulin secretion GO:0032024 36 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
amine metabolic process GO:0009308 38 0.015
defense response to gram negative bacterium GO:0050829 3 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
hormone biosynthetic process GO:0042446 25 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
exocytosis GO:0006887 60 0.015
positive regulation of response to stimulus GO:0048584 285 0.014
cellular response to oxidative stress GO:0034599 76 0.014
single organism behavior GO:0044708 130 0.014
negative regulation of protein maturation GO:1903318 47 0.014
response to ethanol GO:0045471 162 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.014
cellular response to carbohydrate stimulus GO:0071322 72 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
meiotic cell cycle process GO:1903046 3 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.014
lipid localization GO:0010876 62 0.014
response to cytokine GO:0034097 215 0.014
cellular response to nutrient levels GO:0031669 60 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
regulation of secretion GO:0051046 224 0.013
positive regulation of secretion GO:0051047 140 0.013
multicellular organismal homeostasis GO:0048871 49 0.013
positive regulation of molecular function GO:0044093 230 0.013
hormone metabolic process GO:0042445 69 0.013
reproduction GO:0000003 245 0.013
positive regulation of cell death GO:0010942 184 0.013
regulation of secretion by cell GO:1903530 208 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of anatomical structure size GO:0090066 135 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of immune system process GO:0002682 123 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
single organism organelle organization GO:1902589 180 0.013
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.013
response to toxic substance GO:0009636 133 0.013
cellular component morphogenesis GO:0032989 155 0.012
positive regulation of signal transduction GO:0009967 175 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
organic anion transport GO:0015711 132 0.012
negative regulation of signal transduction GO:0009968 83 0.012
regulation of phosphorylation GO:0042325 248 0.012
immune system development GO:0002520 41 0.012
secretion by cell GO:0032940 248 0.012
regulation of growth GO:0040008 105 0.012
brain development GO:0007420 247 0.012
glucose homeostasis GO:0042593 75 0.012
single organism membrane fusion GO:0044801 17 0.012
regulation of blood vessel size GO:0050880 89 0.012
cytoplasmic transport GO:0016482 115 0.012
mitochondrion organization GO:0007005 35 0.012
cellular amine metabolic process GO:0044106 38 0.012
cell cycle GO:0007049 101 0.012
cellular macromolecular complex assembly GO:0034622 58 0.011
regulation of actin nucleation GO:0051125 2 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
muscle system process GO:0003012 115 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
phosphatidic acid biosynthetic process GO:0006654 1 0.011
defense response to other organism GO:0098542 17 0.011
salivary gland development GO:0007431 3 0.011
regulation of odontogenesis GO:0042481 4 0.011
muscle tissue development GO:0060537 58 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
response to wounding GO:0009611 254 0.011
b cell activation involved in immune response GO:0002312 1 0.011
hepaticobiliary system development GO:0061008 90 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of system process GO:0044057 208 0.011
organophosphate catabolic process GO:0046434 148 0.011
positive regulation of response to external stimulus GO:0032103 51 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
negative regulation of protein modification process GO:0031400 52 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
regulation of homeostatic process GO:0032844 101 0.011
gland development GO:0048732 155 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
glycosaminoglycan biosynthetic process GO:0006024 4 0.011
regulation of intracellular transport GO:0032386 65 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
protein heterooligomerization GO:0051291 89 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
regulation of systemic arterial blood pressure GO:0003073 30 0.011
negative regulation of cell differentiation GO:0045596 99 0.010
purine ribonucleotide biosynthetic process GO:0009152 81 0.010
regulation of behavior GO:0050795 61 0.010
glycerophospholipid metabolic process GO:0006650 47 0.010
response to ketone GO:1901654 182 0.010
stem cell division GO:0017145 4 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.010
neuron apoptotic process GO:0051402 88 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
membrane fusion GO:0061025 26 0.010
response to nicotine GO:0035094 51 0.010
response to lithium ion GO:0010226 28 0.010
regulation of dna metabolic process GO:0051052 60 0.010
regulation of t cell activation GO:0050863 23 0.010
positive regulation of organelle organization GO:0010638 48 0.010

Grina disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
cardiovascular system disease DOID:1287 0 0.039
disease of metabolism DOID:0014667 0 0.027
nervous system disease DOID:863 0 0.021