Rattus norvegicus

91 known processes

Hdgf

hepatoma-derived growth factor

Hdgf biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.117
negative regulation of macromolecule metabolic process GO:0010605 260 0.105
regulation of rna metabolic process GO:0051252 391 0.087
macromolecule localization GO:0033036 252 0.079
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.074
rna metabolic process GO:0016070 406 0.069
regulation of nucleic acid templated transcription GO:1903506 380 0.063
transcription dna templated GO:0006351 377 0.056
rna biosynthetic process GO:0032774 380 0.054
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.052
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.052
macromolecular complex subunit organization GO:0043933 339 0.052
negative regulation of biosynthetic process GO:0009890 168 0.052
regulation of cellular component organization GO:0051128 368 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.050
nucleic acid templated transcription GO:0097659 379 0.046
reproduction GO:0000003 245 0.046
protein localization GO:0008104 191 0.044
positive regulation of response to stimulus GO:0048584 285 0.043
cell migration GO:0016477 197 0.043
catabolic process GO:0009056 351 0.042
cellular catabolic process GO:0044248 295 0.041
regulation of rna biosynthetic process GO:2001141 381 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.039
negative regulation of gene expression GO:0010629 199 0.039
intracellular signal transduction GO:0035556 314 0.038
organic substance catabolic process GO:1901575 316 0.037
negative regulation of metabolic process GO:0009892 331 0.037
single organism reproductive process GO:0044702 297 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
organelle organization GO:0006996 266 0.036
positive regulation of signaling GO:0023056 270 0.036
cellular response to stress GO:0033554 269 0.036
immune system process GO:0002376 204 0.036
multi organism reproductive process GO:0044703 262 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
oxoacid metabolic process GO:0043436 290 0.035
regulation of signal transduction GO:0009966 318 0.034
proteolysis GO:0006508 175 0.033
negative regulation of signaling GO:0023057 157 0.033
protein complex subunit organization GO:0071822 302 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
positive regulation of nucleic acid templated transcription GO:1903508 197 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
reproductive process GO:0022414 372 0.031
establishment of protein localization GO:0045184 141 0.030
single organism organelle organization GO:1902589 180 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
regulation of response to stress GO:0080134 126 0.030
neuron projection development GO:0031175 273 0.029
apoptotic process GO:0006915 381 0.029
regulation of protein metabolic process GO:0051246 289 0.029
cell projection organization GO:0030030 302 0.029
organic cyclic compound catabolic process GO:1901361 175 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
regulation of protein modification process GO:0031399 194 0.027
spindle organization GO:0007051 2 0.027
protein complex assembly GO:0006461 263 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
intracellular transport GO:0046907 185 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
neuron differentiation GO:0030182 368 0.026
protein complex biogenesis GO:0070271 263 0.026
gastrulation GO:0007369 2 0.026
positive regulation of cell communication GO:0010647 271 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
dendrite development GO:0016358 72 0.026
cellular amine metabolic process GO:0044106 38 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
cell morphogenesis GO:0000902 142 0.025
regulation of cell projection organization GO:0031344 175 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
cellular component movement GO:0006928 248 0.025
negative regulation of protein metabolic process GO:0051248 114 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
macromolecular complex assembly GO:0065003 273 0.024
mapk cascade GO:0000165 140 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
organic acid metabolic process GO:0006082 292 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
cytoskeleton organization GO:0007010 111 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
cellular component assembly GO:0022607 360 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
response to cytokine GO:0034097 215 0.022
heterocycle catabolic process GO:0046700 167 0.022
regulation of protein localization GO:0032880 81 0.022
response to corticosteroid GO:0031960 235 0.022
cell projection morphogenesis GO:0048858 123 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
cellular component biogenesis GO:0044085 368 0.022
regulation of cell differentiation GO:0045595 320 0.022
positive regulation of gene expression GO:0010628 244 0.022
growth GO:0040007 165 0.022
homeostatic process GO:0042592 331 0.021
response to growth factor GO:0070848 189 0.021
cellular component morphogenesis GO:0032989 155 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
regulation of apoptotic process GO:0042981 335 0.021
response to decreased oxygen levels GO:0036293 237 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
protein transport GO:0015031 132 0.020
multicellular organism reproduction GO:0032504 233 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
regulation of proteasomal protein catabolic process GO:0061136 4 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
axis specification GO:0009798 4 0.020
negative regulation of cell communication GO:0010648 158 0.020
dna metabolic process GO:0006259 96 0.020
regulation of programmed cell death GO:0043067 341 0.019
central nervous system development GO:0007417 311 0.019
defense response GO:0006952 194 0.019
chromosome segregation GO:0007059 2 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
positive regulation of transport GO:0051050 245 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
protein phosphorylation GO:0006468 345 0.019
positive regulation of developmental process GO:0051094 283 0.019
localization of cell GO:0051674 202 0.019
cation transport GO:0006812 382 0.019
positive regulation of signal transduction GO:0009967 175 0.018
programmed cell death GO:0012501 392 0.018
regulation of cellular response to stress GO:0080135 49 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
behavior GO:0007610 205 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
protein modification by small protein conjugation or removal GO:0070647 35 0.017
positive regulation of cell death GO:0010942 184 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
amine metabolic process GO:0009308 38 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
positive regulation of programmed cell death GO:0043068 157 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
tissue development GO:0009888 252 0.017
aging GO:0007568 241 0.017
gamete generation GO:0007276 124 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
response to extracellular stimulus GO:0009991 380 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
regulation of neurogenesis GO:0050767 247 0.016
head development GO:0060322 247 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
locomotion GO:0040011 237 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
regulation of fat cell differentiation GO:0045598 3 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.016
developmental process involved in reproduction GO:0003006 159 0.016
response to wounding GO:0009611 254 0.016
cytoplasmic transport GO:0016482 115 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
nucleocytoplasmic transport GO:0006913 48 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
cellular protein localization GO:0034613 122 0.015
nucleotide metabolic process GO:0009117 279 0.015
protein oligomerization GO:0051259 191 0.015
organophosphate metabolic process GO:0019637 370 0.015
regulation of proteolysis GO:0030162 66 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
regulation of kinase activity GO:0043549 117 0.015
response to hypoxia GO:0001666 231 0.015
regulation of growth GO:0040008 105 0.015
cell motility GO:0048870 202 0.015
multicellular organism growth GO:0035264 1 0.015
positive regulation of molecular function GO:0044093 230 0.015
cellular homeostasis GO:0019725 252 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
regulation of cell development GO:0060284 263 0.014
response to inorganic substance GO:0010035 377 0.014
cell growth GO:0016049 104 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
single organism catabolic process GO:0044712 283 0.014
regulation of organelle organization GO:0033043 80 0.014
carboxylic acid metabolic process GO:0019752 289 0.014
organophosphate catabolic process GO:0046434 148 0.014
negative regulation of developmental process GO:0051093 125 0.014
developmental growth GO:0048589 100 0.014
cellular ketone metabolic process GO:0042180 51 0.014
vesicle mediated transport GO:0016192 181 0.014
regulation of phosphorylation GO:0042325 248 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
response to nutrient levels GO:0031667 370 0.014
response to glucocorticoid GO:0051384 223 0.014
cell fate determination GO:0001709 2 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of cellular localization GO:0060341 263 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
positive regulation of jnk cascade GO:0046330 13 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
response to oxygen levels GO:0070482 265 0.013
single organism biosynthetic process GO:0044711 342 0.013
establishment of protein localization to organelle GO:0072594 44 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
nuclear transport GO:0051169 49 0.013
cell cycle GO:0007049 101 0.013
reproductive system development GO:0061458 128 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
oxidation reduction process GO:0055114 304 0.013
cell cycle checkpoint GO:0000075 2 0.013
dendrite morphogenesis GO:0048813 43 0.013
cellular response to organic cyclic compound GO:0071407 202 0.012
cellular macromolecule localization GO:0070727 122 0.012
negative regulation of signal transduction GO:0009968 83 0.012
chemical homeostasis GO:0048878 292 0.012
neuron development GO:0048666 286 0.012
aromatic compound catabolic process GO:0019439 168 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of molecular function GO:0065009 398 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of secretion by cell GO:1903530 208 0.012
response to toxic substance GO:0009636 133 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
sexual reproduction GO:0019953 148 0.012
secretion GO:0046903 307 0.012
immune response GO:0006955 104 0.012
chromatin assembly or disassembly GO:0006333 1 0.011
nucleotide catabolic process GO:0009166 139 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
response to acid chemical GO:0001101 222 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
regulation of catalytic activity GO:0050790 304 0.011
macromolecule catabolic process GO:0009057 58 0.011
embryonic pattern specification GO:0009880 1 0.011
cell cycle process GO:0022402 57 0.011
brain development GO:0007420 247 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
response to carbohydrate GO:0009743 183 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
regulation of hormone levels GO:0010817 187 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.011
protein autophosphorylation GO:0046777 66 0.011
gonad development GO:0008406 104 0.011
regulation of response to wounding GO:1903034 69 0.011
dephosphorylation GO:0016311 98 0.011
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
signal release GO:0023061 145 0.011
regulation of nervous system development GO:0051960 264 0.011
regulation of neuron differentiation GO:0045664 208 0.010
embryonic axis specification GO:0000578 1 0.010
negative regulation of molecular function GO:0044092 133 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
neuron projection morphogenesis GO:0048812 122 0.010
regulation of cell proliferation GO:0042127 359 0.010
regulation of secretion GO:0051046 224 0.010
regulation of neuron projection development GO:0010975 161 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
purine containing compound metabolic process GO:0072521 253 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
sex differentiation GO:0007548 113 0.010
protein targeting GO:0006605 61 0.010

Hdgf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
organ system cancer DOID:0050686 0 0.012