Rattus norvegicus

37 known processes

Slc22a5

solute carrier family 22 (organic cation/carnitine transporter), member 5

(Aliases: UST2r,OCTN2,CT1)

Slc22a5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.211
Mouse
oxoacid metabolic process GO:0043436 290 0.191
Mouse
organic acid metabolic process GO:0006082 292 0.168
Mouse
cellular lipid metabolic process GO:0044255 208 0.116
fatty acid metabolic process GO:0006631 99 0.112
response to extracellular stimulus GO:0009991 380 0.106
lipid metabolic process GO:0006629 283 0.103
response to inorganic substance GO:0010035 377 0.092
Zebrafish
catabolic process GO:0009056 351 0.092
monocarboxylic acid metabolic process GO:0032787 152 0.091
Mouse
protein complex biogenesis GO:0070271 263 0.076
Rat
organic substance catabolic process GO:1901575 316 0.076
cellular catabolic process GO:0044248 295 0.071
response to nutrient GO:0007584 248 0.070
response to nutrient levels GO:0031667 370 0.055
cellular component assembly GO:0022607 360 0.051
Rat
single organism biosynthetic process GO:0044711 342 0.045
macromolecular complex subunit organization GO:0043933 339 0.045
Rat
transmembrane transport GO:0055085 412 0.044
protein oligomerization GO:0051259 191 0.043
Rat
single organism catabolic process GO:0044712 283 0.042
regulation of nucleic acid templated transcription GO:1903506 380 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.041
cell projection organization GO:0030030 302 0.041
response to metal ion GO:0010038 253 0.040
Zebrafish
nucleic acid templated transcription GO:0097659 379 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
response to organophosphorus GO:0046683 102 0.038
regulation of signal transduction GO:0009966 318 0.038
nitrogen compound transport GO:0071705 229 0.038
anion transport GO:0006820 178 0.037
protein complex subunit organization GO:0071822 302 0.037
Rat
response to tumor necrosis factor GO:0034612 56 0.037
neuron differentiation GO:0030182 368 0.037
protein complex assembly GO:0006461 263 0.037
Rat
small molecule catabolic process GO:0044282 59 0.036
negative regulation of metabolic process GO:0009892 331 0.036
organelle organization GO:0006996 266 0.036
Mouse
organic hydroxy compound metabolic process GO:1901615 115 0.036
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.036
carboxylic acid catabolic process GO:0046395 49 0.036
oxidation reduction process GO:0055114 304 0.035
intracellular signal transduction GO:0035556 314 0.035
regulation of apoptotic process GO:0042981 335 0.035
response to external biotic stimulus GO:0043207 221 0.034
Rat
transcription dna templated GO:0006351 377 0.034
regulation of transcription dna templated GO:0006355 374 0.034
carboxylic acid transport GO:0046942 115 0.033
aging GO:0007568 241 0.033
response to bacterium GO:0009617 200 0.033
rna metabolic process GO:0016070 406 0.033
macromolecular complex assembly GO:0065003 273 0.033
Rat
cellular component biogenesis GO:0044085 368 0.033
Rat
response to purine containing compound GO:0014074 126 0.032
lipid biosynthetic process GO:0008610 128 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
defense response GO:0006952 194 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
neuron development GO:0048666 286 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
response to estrogen GO:0043627 232 0.030
response to growth factor GO:0070848 189 0.030
secretion GO:0046903 307 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
organic acid transport GO:0015849 116 0.030
positive regulation of gene expression GO:0010628 244 0.029
regulation of rna metabolic process GO:0051252 391 0.029
programmed cell death GO:0012501 392 0.029
regulation of neuron differentiation GO:0045664 208 0.029
cellular ketone metabolic process GO:0042180 51 0.028
neuron projection development GO:0031175 273 0.028
response to oxidative stress GO:0006979 186 0.028
chemical homeostasis GO:0048878 292 0.028
cellular protein localization GO:0034613 122 0.027
regulation of protein metabolic process GO:0051246 289 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
protein homooligomerization GO:0051260 91 0.027
Rat
regulation of intracellular signal transduction GO:1902531 218 0.027
gland development GO:0048732 155 0.027
organonitrogen compound biosynthetic process GO:1901566 167 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
central nervous system development GO:0007417 311 0.026
organic acid catabolic process GO:0016054 49 0.026
response to peptide GO:1901652 292 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
response to ethanol GO:0045471 162 0.026
reproductive process GO:0022414 372 0.026
Mouse
fatty acid beta oxidation GO:0006635 22 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
regulation of multicellular organismal development GO:2000026 376 0.025
cellular response to stress GO:0033554 269 0.025
response to decreased oxygen levels GO:0036293 237 0.025
head development GO:0060322 247 0.025
organonitrogen compound catabolic process GO:1901565 179 0.025
cellular response to lipid GO:0071396 201 0.025
response to corticosteroid GO:0031960 235 0.025
hormone transport GO:0009914 121 0.024
Rat
regulation of cell differentiation GO:0045595 320 0.024
organic acid biosynthetic process GO:0016053 83 0.024
regulation of nervous system development GO:0051960 264 0.024
protein phosphorylation GO:0006468 345 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
regulation of molecular function GO:0065009 398 0.024
response to monosaccharide GO:0034284 159 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
single organism reproductive process GO:0044702 297 0.024
negative regulation of cell differentiation GO:0045596 99 0.024
homeostatic process GO:0042592 331 0.023
Human
intracellular transport GO:0046907 185 0.023
apoptotic process GO:0006915 381 0.023
response to biotic stimulus GO:0009607 226 0.023
Rat
regulation of protein modification process GO:0031399 194 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
heterocycle catabolic process GO:0046700 167 0.023
regulation of cell proliferation GO:0042127 359 0.023
negative regulation of cell death GO:0060548 229 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
response to vitamin GO:0033273 131 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
small molecule biosynthetic process GO:0044283 124 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
alcohol metabolic process GO:0006066 77 0.023
cellular amine metabolic process GO:0044106 38 0.022
immune system process GO:0002376 204 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
rna biosynthetic process GO:0032774 380 0.022
response to acid chemical GO:0001101 222 0.022
Rat
response to ketone GO:1901654 182 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
response to cytokine GO:0034097 215 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
amide transport GO:0042886 105 0.022
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
response to hypoxia GO:0001666 231 0.022
single organism intracellular transport GO:1902582 166 0.022
response to oxygen levels GO:0070482 265 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
regulation of rna biosynthetic process GO:2001141 381 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
regulation of phosphorylation GO:0042325 248 0.021
response to carbohydrate GO:0009743 183 0.021
negative regulation of gene expression GO:0010629 199 0.021
regulation of catalytic activity GO:0050790 304 0.021
positive regulation of molecular function GO:0044093 230 0.021
macromolecule localization GO:0033036 252 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
response to wounding GO:0009611 254 0.021
purine containing compound metabolic process GO:0072521 253 0.021
carboxylic acid biosynthetic process GO:0046394 83 0.020
neurological system process GO:0050877 219 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
establishment of protein localization GO:0045184 141 0.020
regeneration GO:0031099 163 0.020
cellular response to tumor necrosis factor GO:0071356 46 0.020
response to camp GO:0051591 91 0.020
cellular chemical homeostasis GO:0055082 247 0.020
regulation of hormone levels GO:0010817 187 0.020
Rat
response to reactive oxygen species GO:0000302 120 0.020
cation transport GO:0006812 382 0.020
cellular homeostasis GO:0019725 252 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
gliogenesis GO:0042063 93 0.020
single organism organelle organization GO:1902589 180 0.020
regulation of cell development GO:0060284 263 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
regulation of cell projection organization GO:0031344 175 0.019
organophosphate metabolic process GO:0019637 370 0.019
negative regulation of neurogenesis GO:0050768 78 0.019
organic anion transport GO:0015711 132 0.019
amine metabolic process GO:0009308 38 0.019
positive regulation of signal transduction GO:0009967 175 0.019
response to peptide hormone GO:0043434 278 0.018
secretion by cell GO:0032940 248 0.018
cellular component movement GO:0006928 248 0.018
regulation of secretion GO:0051046 224 0.018
regulation of programmed cell death GO:0043067 341 0.018
oligopeptide transport GO:0006857 4 0.018
Rat
cellular macromolecule localization GO:0070727 122 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
axis specification GO:0009798 4 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
response to mechanical stimulus GO:0009612 134 0.017
cellular response to peptide GO:1901653 133 0.017
renal system development GO:0072001 67 0.017
response to toxic substance GO:0009636 133 0.017
Zebrafish
glial cell differentiation GO:0010001 65 0.017
cellular response to external stimulus GO:0071496 118 0.017
negative regulation of cell development GO:0010721 82 0.017
response to lipopolysaccharide GO:0032496 191 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
linoleic acid metabolic process GO:0043651 4 0.017
positive regulation of transport GO:0051050 245 0.017
ion transmembrane transport GO:0034220 365 0.017
response to hexose GO:0009746 144 0.017
regulation of neurogenesis GO:0050767 247 0.016
anion transmembrane transport GO:0098656 77 0.016
cytoplasmic transport GO:0016482 115 0.016
growth GO:0040007 165 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
monocarboxylic acid transport GO:0015718 52 0.016
tissue development GO:0009888 252 0.016
nucleoside metabolic process GO:0009116 179 0.016
circulatory system process GO:0003013 183 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
Zebrafish
peptide transport GO:0015833 97 0.016
Rat
positive regulation of developmental process GO:0051094 283 0.016
lipid oxidation GO:0034440 30 0.016
response to glucocorticoid GO:0051384 223 0.016
l glutamate import GO:0051938 2 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
gastrulation GO:0007369 2 0.016
negative regulation of cell communication GO:0010648 158 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
negative regulation of molecular function GO:0044092 133 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
Human
purine ribonucleotide metabolic process GO:0009150 227 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
negative regulation of nervous system development GO:0051961 79 0.015
reproductive system development GO:0061458 128 0.015
Mouse
protein heterooligomerization GO:0051291 89 0.015
kidney development GO:0001822 67 0.015
fatty acid catabolic process GO:0009062 26 0.015
protein localization GO:0008104 191 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
response to glucose GO:0009749 136 0.015
long chain fatty acid metabolic process GO:0001676 32 0.015
fatty acid oxidation GO:0019395 29 0.015
aromatic compound catabolic process GO:0019439 168 0.015
eye morphogenesis GO:0048592 4 0.015
regulation of catabolic process GO:0009894 113 0.015
brain development GO:0007420 247 0.015
protein transport GO:0015031 132 0.015
positive regulation of fatty acid beta oxidation GO:0032000 4 0.015
regulation of cellular component organization GO:0051128 368 0.015
cell motility GO:0048870 202 0.015
reproduction GO:0000003 245 0.014
negative regulation of protein import into nucleus translocation GO:0033159 1 0.014
organophosphate catabolic process GO:0046434 148 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
ras protein signal transduction GO:0007265 29 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
organ regeneration GO:0031100 101 0.014
localization of cell GO:0051674 202 0.014
intracellular protein transport GO:0006886 79 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
inflammatory response GO:0006954 150 0.014
single organism behavior GO:0044708 130 0.014
multicellular organism reproduction GO:0032504 233 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of nervous system development GO:0051962 178 0.014
blood circulation GO:0008015 183 0.014
response to radiation GO:0009314 137 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
regulation of secretion by cell GO:1903530 208 0.014
positive regulation of cell communication GO:0010647 271 0.014
negative regulation of signaling GO:0023057 157 0.014
positive regulation of cell death GO:0010942 184 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
cell cell signaling GO:0007267 335 0.014
proteolysis GO:0006508 175 0.014
regulation of cellular component movement GO:0051270 150 0.014
response to hydrogen peroxide GO:0042542 89 0.013
positive regulation of signaling GO:0023056 270 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
regulation of cellular localization GO:0060341 263 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
reproductive structure development GO:0048608 128 0.013
Mouse
regulation of membrane potential GO:0042391 110 0.013
glycerolipid metabolic process GO:0046486 67 0.013
behavior GO:0007610 205 0.013
Mouse
positive regulation of transcription dna templated GO:0045893 197 0.013
cell projection morphogenesis GO:0048858 123 0.013
positive regulation of cell development GO:0010720 176 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
multi organism reproductive process GO:0044703 262 0.013
regulation of neuron projection development GO:0010975 161 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
neural crest cell development GO:0014032 2 0.013
calcium ion homeostasis GO:0055074 162 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
cell morphogenesis GO:0000902 142 0.012
terpenoid metabolic process GO:0006721 37 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
neuron projection morphogenesis GO:0048812 122 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
membrane organization GO:0061024 94 0.012
adult locomotory behavior GO:0008344 4 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
multi multicellular organism process GO:0044706 138 0.012
response to estradiol GO:0032355 164 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
regulation of locomotion GO:0040012 148 0.012
ion homeostasis GO:0050801 212 0.012
lipid modification GO:0030258 52 0.012
nucleotide catabolic process GO:0009166 139 0.012
monocarboxylic acid catabolic process GO:0072329 28 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cell part morphogenesis GO:0032990 123 0.012
cation homeostasis GO:0055080 195 0.012
regulation of anatomical structure size GO:0090066 135 0.012
carbohydrate metabolic process GO:0005975 130 0.012
response to starvation GO:0042594 59 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
regulation of metal ion transport GO:0010959 118 0.012
vesicle mediated transport GO:0016192 181 0.012
lipid storage GO:0019915 1 0.011
nucleotide metabolic process GO:0009117 279 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
single organism cellular localization GO:1902580 102 0.011
maintenance of location GO:0051235 17 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
lipid catabolic process GO:0016042 46 0.011
positive regulation of ion transport GO:0043270 94 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
negative regulation of signal transduction GO:0009968 83 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
cellular component morphogenesis GO:0032989 155 0.011
cytokinetic process GO:0032506 1 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
organ morphogenesis GO:0009887 75 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
female pregnancy GO:0007565 122 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
steroid metabolic process GO:0008202 73 0.011
coenzyme metabolic process GO:0006732 86 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
response to insulin GO:0032868 133 0.011
multicellular organism growth GO:0035264 1 0.011
neuron death GO:0070997 127 0.010
lipid transport GO:0006869 61 0.010
amino acid transport GO:0006865 70 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.010
regulation of homeostatic process GO:0032844 101 0.010
Human
rhythmic process GO:0048511 156 0.010
vitamin biosynthetic process GO:0009110 3 0.010
regulation of peptide transport GO:0090087 87 0.010
cell cycle GO:0007049 101 0.010
carnitine metabolic process GO:0009437 3 0.010
Mouse
bile acid biosynthetic process GO:0006699 3 0.010
cellular response to lipopolysaccharide GO:0071222 55 0.010
positive regulation of neuron migration GO:2001224 2 0.010
response to blue light GO:0009637 1 0.010
liver development GO:0001889 90 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
learning or memory GO:0007611 90 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
macrophage chemotaxis GO:0048246 2 0.010
cellular response to biotic stimulus GO:0071216 59 0.010

Slc22a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
sensory system disease DOID:0050155 0 0.023
musculoskeletal system disease DOID:17 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
disease of metabolism DOID:0014667 0 0.013
Human
inherited metabolic disorder DOID:655 0 0.013
Human
central nervous system disease DOID:331 0 0.012