Rattus norvegicus

33 known processes

Lrat

lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)

Lrat biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.129
organic acid metabolic process GO:0006082 292 0.100
oxoacid metabolic process GO:0043436 290 0.097
cellular lipid metabolic process GO:0044255 208 0.090
cellular component assembly GO:0022607 360 0.089
macromolecular complex subunit organization GO:0043933 339 0.085
regulation of cell proliferation GO:0042127 359 0.080
regulation of phosphate metabolic process GO:0019220 349 0.079
regulation of phosphorus metabolic process GO:0051174 349 0.079
regulation of multicellular organismal development GO:2000026 376 0.074
single organism biosynthetic process GO:0044711 342 0.073
organophosphate metabolic process GO:0019637 370 0.067
reproductive process GO:0022414 372 0.067
anatomical structure morphogenesis GO:0009653 298 0.060
positive regulation of multicellular organismal process GO:0051240 387 0.060
protein complex assembly GO:0006461 263 0.060
intracellular signal transduction GO:0035556 314 0.059
cellular response to endogenous stimulus GO:0071495 377 0.055
programmed cell death GO:0012501 392 0.053
rna biosynthetic process GO:0032774 380 0.051
macromolecule localization GO:0033036 252 0.050
regulation of rna biosynthetic process GO:2001141 381 0.050
cellular amino acid metabolic process GO:0006520 107 0.050
regulation of catalytic activity GO:0050790 304 0.049
multicellular organism reproduction GO:0032504 233 0.049
regulation of hormone levels GO:0010817 187 0.048
g protein coupled receptor signaling pathway GO:0007186 242 0.047
transcription dna templated GO:0006351 377 0.046
regulation of molecular function GO:0065009 398 0.046
negative regulation of programmed cell death GO:0043069 183 0.045
nucleic acid templated transcription GO:0097659 379 0.045
cation transport GO:0006812 382 0.044
regulation of programmed cell death GO:0043067 341 0.043
transmembrane transport GO:0055085 412 0.043
positive regulation of biosynthetic process GO:0009891 319 0.042
single organism reproductive process GO:0044702 297 0.042
cellular component biogenesis GO:0044085 368 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
regulation of cell differentiation GO:0045595 320 0.041
macromolecular complex assembly GO:0065003 273 0.039
lipid metabolic process GO:0006629 283 0.038
organonitrogen compound biosynthetic process GO:1901566 167 0.037
positive regulation of cell proliferation GO:0008284 249 0.037
positive regulation of catalytic activity GO:0043085 184 0.037
rhythmic process GO:0048511 156 0.037
positive regulation of molecular function GO:0044093 230 0.036
regulation of cellular component organization GO:0051128 368 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.036
multicellular organismal reproductive process GO:0048609 233 0.036
response to extracellular stimulus GO:0009991 380 0.036
multi organism reproductive process GO:0044703 262 0.036
response to oxygen levels GO:0070482 265 0.035
positive regulation of cell communication GO:0010647 271 0.035
developmental process involved in reproduction GO:0003006 159 0.035
response to decreased oxygen levels GO:0036293 237 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
amine metabolic process GO:0009308 38 0.034
small molecule biosynthetic process GO:0044283 124 0.034
rna metabolic process GO:0016070 406 0.034
response to toxic substance GO:0009636 133 0.033
protein phosphorylation GO:0006468 345 0.033
protein oligomerization GO:0051259 191 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
neurological system process GO:0050877 219 0.032
chemical homeostasis GO:0048878 292 0.032
regulation of rna metabolic process GO:0051252 391 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
negative regulation of metabolic process GO:0009892 331 0.031
central nervous system development GO:0007417 311 0.031
response to inorganic substance GO:0010035 377 0.031
steroid metabolic process GO:0008202 73 0.030
neuron differentiation GO:0030182 368 0.030
regulation of nervous system development GO:0051960 264 0.030
response to estrogen GO:0043627 232 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
regulation of secretion by cell GO:1903530 208 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
positive regulation of developmental process GO:0051094 283 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
apoptotic process GO:0006915 381 0.029
organic hydroxy compound metabolic process GO:1901615 115 0.028
secretion GO:0046903 307 0.028
regulation of cellular localization GO:0060341 263 0.028
reproduction GO:0000003 245 0.028
response to wounding GO:0009611 254 0.028
organelle organization GO:0006996 266 0.028
regulation of phosphorylation GO:0042325 248 0.028
organic acid biosynthetic process GO:0016053 83 0.028
positive regulation of protein modification process GO:0031401 142 0.028
metal ion transport GO:0030001 289 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
anion transport GO:0006820 178 0.027
regulation of transcription dna templated GO:0006355 374 0.027
secretion by cell GO:0032940 248 0.027
response to cytokine GO:0034097 215 0.027
organic substance catabolic process GO:1901575 316 0.026
response to ketone GO:1901654 182 0.026
catabolic process GO:0009056 351 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
positive regulation of programmed cell death GO:0043068 157 0.026
response to other organism GO:0051707 220 0.026
regulation of signal transduction GO:0009966 318 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
nucleotide metabolic process GO:0009117 279 0.026
response to nutrient levels GO:0031667 370 0.026
endocytosis GO:0006897 84 0.026
reproductive structure development GO:0048608 128 0.025
protein complex subunit organization GO:0071822 302 0.025
muscle cell proliferation GO:0033002 84 0.025
positive regulation of gene expression GO:0010628 244 0.025
female gonad development GO:0008585 53 0.025
regulation of growth GO:0040008 105 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
homeostatic process GO:0042592 331 0.025
response to external biotic stimulus GO:0043207 221 0.024
heart morphogenesis GO:0003007 3 0.024
cellular amine metabolic process GO:0044106 38 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
negative regulation of cell proliferation GO:0008285 119 0.024
cellular catabolic process GO:0044248 295 0.024
vesicle mediated transport GO:0016192 181 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
regulation of apoptotic process GO:0042981 335 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
neuron development GO:0048666 286 0.022
cell cell signaling GO:0007267 335 0.022
regulation of cell development GO:0060284 263 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
single organism catabolic process GO:0044712 283 0.022
cardiovascular system development GO:0072358 134 0.022
cell projection organization GO:0030030 302 0.022
alcohol metabolic process GO:0006066 77 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
hormone metabolic process GO:0042445 69 0.022
positive regulation of rna metabolic process GO:0051254 203 0.021
lipid localization GO:0010876 62 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
circulatory system development GO:0072359 134 0.021
lipid biosynthetic process GO:0008610 128 0.021
negative regulation of multicellular organismal process GO:0051241 203 0.021
response to lipopolysaccharide GO:0032496 191 0.021
locomotion GO:0040011 237 0.021
protein homooligomerization GO:0051260 91 0.021
cellular ketone metabolic process GO:0042180 51 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
signal transduction by phosphorylation GO:0023014 144 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
organ formation GO:0048645 3 0.020
positive regulation of cell development GO:0010720 176 0.020
growth GO:0040007 165 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
biological adhesion GO:0022610 110 0.020
positive regulation of signaling GO:0023056 270 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
regulation of system process GO:0044057 208 0.020
negative regulation of cell death GO:0060548 229 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
protein heterooligomerization GO:0051291 89 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of neurogenesis GO:0050767 247 0.019
multicellular organismal homeostasis GO:0048871 49 0.019
sexual reproduction GO:0019953 148 0.019
regulation of cellular component movement GO:0051270 150 0.019
neuron projection development GO:0031175 273 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
response to metal ion GO:0010038 253 0.019
purine containing compound metabolic process GO:0072521 253 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
negative regulation of developmental process GO:0051093 125 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
positive regulation of nervous system development GO:0051962 178 0.019
multi multicellular organism process GO:0044706 138 0.018
reproductive system development GO:0061458 128 0.018
nitrogen compound transport GO:0071705 229 0.018
divalent inorganic cation transport GO:0072511 134 0.018
organ morphogenesis GO:0009887 75 0.018
cation transmembrane transport GO:0098655 263 0.018
protein complex biogenesis GO:0070271 263 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
regulation of protein metabolic process GO:0051246 289 0.018
ion homeostasis GO:0050801 212 0.018
development of primary sexual characteristics GO:0045137 107 0.018
cellular chemical homeostasis GO:0055082 247 0.018
gonad development GO:0008406 104 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
retinal metabolic process GO:0042574 3 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
single organism organelle organization GO:1902589 180 0.017
smooth muscle cell proliferation GO:0048659 77 0.017
cellular component movement GO:0006928 248 0.017
calcium ion homeostasis GO:0055074 162 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
response to corticosteroid GO:0031960 235 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
cellular homeostasis GO:0019725 252 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
response to peptide GO:1901652 292 0.017
regulation of protein modification process GO:0031399 194 0.017
renal system development GO:0072001 67 0.017
proteolysis GO:0006508 175 0.017
response to peptide hormone GO:0043434 278 0.017
cellular cation homeostasis GO:0030003 180 0.016
anterior posterior pattern specification GO:0009952 1 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
cellular modified amino acid metabolic process GO:0006575 61 0.016
positive regulation of cell migration GO:0030335 96 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
response to growth factor GO:0070848 189 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
response to temperature stimulus GO:0009266 94 0.016
regulation of mapk cascade GO:0043408 116 0.016
sorbitol biosynthetic process GO:0006061 1 0.016
cell morphogenesis GO:0000902 142 0.016
regulation of locomotion GO:0040012 148 0.016
brain development GO:0007420 247 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
protein localization GO:0008104 191 0.016
positive regulation of signal transduction GO:0009967 175 0.016
oxidation reduction process GO:0055114 304 0.016
kidney development GO:0001822 67 0.016
lipid transport GO:0006869 61 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
blood vessel morphogenesis GO:0048514 58 0.015
regulation of response to external stimulus GO:0032101 106 0.015
response to insulin GO:0032868 133 0.015
developmental induction GO:0031128 2 0.015
cellular component morphogenesis GO:0032989 155 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of transferase activity GO:0051347 81 0.015
head development GO:0060322 247 0.015
cofactor metabolic process GO:0051186 95 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
response to carbohydrate GO:0009743 183 0.015
response to biotic stimulus GO:0009607 226 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
cell migration GO:0016477 197 0.015
behavior GO:0007610 205 0.015
sulfur compound metabolic process GO:0006790 70 0.015
phospholipid metabolic process GO:0006644 61 0.015
response to hypoxia GO:0001666 231 0.015
respiratory system development GO:0060541 45 0.015
ion transmembrane transport GO:0034220 365 0.014
positive regulation of transport GO:0051050 245 0.014
epithelial cell proliferation GO:0050673 54 0.014
blood vessel development GO:0001568 69 0.014
regulation of homeostatic process GO:0032844 101 0.014
regulation of secretion GO:0051046 224 0.014
regulation of membrane potential GO:0042391 110 0.014
gamete generation GO:0007276 124 0.014
dna metabolic process GO:0006259 96 0.014
single organismal cell cell adhesion GO:0016337 42 0.014
cell adhesion GO:0007155 110 0.014
localization of cell GO:0051674 202 0.014
muscle system process GO:0003012 115 0.014
positive regulation of cell death GO:0010942 184 0.014
wound healing GO:0042060 122 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
cholesterol homeostasis GO:0042632 3 0.014
receptor mediated endocytosis GO:0006898 42 0.014
heterocycle catabolic process GO:0046700 167 0.014
vasculature development GO:0001944 70 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
positive regulation of kinase activity GO:0033674 77 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of neuron differentiation GO:0045664 208 0.013
regeneration GO:0031099 163 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
intestinal absorption GO:0050892 3 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
response to vitamin GO:0033273 131 0.013
cellular ion homeostasis GO:0006873 184 0.013
gastrulation GO:0007369 2 0.013
peptide biosynthetic process GO:0043043 3 0.013
response to acid chemical GO:0001101 222 0.013
cellular macromolecule localization GO:0070727 122 0.013
axis specification GO:0009798 4 0.013
mesoderm development GO:0007498 2 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
circadian rhythm GO:0007623 88 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
regulation of cell motility GO:2000145 131 0.013
sex differentiation GO:0007548 113 0.013
regulation of hydrolase activity GO:0051336 143 0.013
angiogenesis GO:0001525 53 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
ossification GO:0001503 70 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
urogenital system development GO:0001655 78 0.012
liver development GO:0001889 90 0.012
regulation of cell projection organization GO:0031344 175 0.012
regulation of neuron projection development GO:0010975 161 0.012
ras protein signal transduction GO:0007265 29 0.012
actin filament based process GO:0030029 86 0.012
organ induction GO:0001759 1 0.012
gliogenesis GO:0042063 93 0.012
regulation of cell migration GO:0030334 128 0.012
cellular response to external stimulus GO:0071496 118 0.012
negative regulation of cell communication GO:0010648 158 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
response to bacterium GO:0009617 200 0.012
regulation of transferase activity GO:0051338 123 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
cytoplasmic transport GO:0016482 115 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
metal ion homeostasis GO:0055065 186 0.012
formation of primary germ layer GO:0001704 1 0.012
response to ethanol GO:0045471 162 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
regulation of cell growth GO:0001558 85 0.012
response to glucocorticoid GO:0051384 223 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
carbohydrate metabolic process GO:0005975 130 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
nucleoside metabolic process GO:0009116 179 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
monocarboxylic acid transport GO:0015718 52 0.011
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
peptidyl amino acid modification GO:0018193 126 0.011
sulfur compound biosynthetic process GO:0044272 19 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
action potential GO:0001508 54 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
muscle contraction GO:0006936 88 0.011
chemosensory behavior GO:0007635 2 0.011
response to glucose GO:0009749 136 0.011
negative regulation of molecular function GO:0044092 133 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.011
regulation of kinase activity GO:0043549 117 0.011
glial cell differentiation GO:0010001 65 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
specification of organ identity GO:0010092 2 0.011
salivary gland development GO:0007431 3 0.011
cellular response to stress GO:0033554 269 0.011
alpha amino acid metabolic process GO:1901605 71 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
negative regulation of transport GO:0051051 136 0.011
muscle structure development GO:0061061 87 0.011
signal release GO:0023061 145 0.011
regulation of organ formation GO:0003156 2 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
cellular hormone metabolic process GO:0034754 49 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
glycerolipid metabolic process GO:0046486 67 0.010
blood circulation GO:0008015 183 0.010
spermatogenesis GO:0007283 99 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
embryonic pattern specification GO:0009880 1 0.010
lipid storage GO:0019915 1 0.010
single organism intracellular transport GO:1902582 166 0.010
chromosome segregation GO:0007059 2 0.010
regulation of anatomical structure size GO:0090066 135 0.010
tube formation GO:0035148 3 0.010
aging GO:0007568 241 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
regulation of protein localization GO:0032880 81 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010

Lrat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
musculoskeletal system disease DOID:17 0 0.014
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.010