Rattus norvegicus

0 known processes

Ankle2

ankyrin repeat and LEM domain containing 2

(Aliases: RGD1310191)

Ankle2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.142
cellular component biogenesis GO:0044085 368 0.109
macromolecular complex assembly GO:0065003 273 0.090
positive regulation of biosynthetic process GO:0009891 319 0.085
protein complex assembly GO:0006461 263 0.084
negative regulation of macromolecule metabolic process GO:0010605 260 0.083
regulation of protein metabolic process GO:0051246 289 0.067
Human
protein complex subunit organization GO:0071822 302 0.067
cellular component assembly GO:0022607 360 0.066
negative regulation of gene expression GO:0010629 199 0.066
organophosphate metabolic process GO:0019637 370 0.063
regulation of phosphorus metabolic process GO:0051174 349 0.059
Human
regulation of molecular function GO:0065009 398 0.059
negative regulation of metabolic process GO:0009892 331 0.058
Human
programmed cell death GO:0012501 392 0.058
protein complex biogenesis GO:0070271 263 0.056
rna biosynthetic process GO:0032774 380 0.055
catabolic process GO:0009056 351 0.050
regulation of phosphate metabolic process GO:0019220 349 0.049
Human
negative regulation of cellular metabolic process GO:0031324 281 0.049
Human
regulation of rna metabolic process GO:0051252 391 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
regulation of cellular protein metabolic process GO:0032268 267 0.047
Human
transcription dna templated GO:0006351 377 0.047
regulation of apoptotic process GO:0042981 335 0.044
cellular amino acid metabolic process GO:0006520 107 0.043
regulation of signal transduction GO:0009966 318 0.043
nucleic acid templated transcription GO:0097659 379 0.043
reproductive process GO:0022414 372 0.042
regulation of protein phosphorylation GO:0001932 183 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
regulation of transcription dna templated GO:0006355 374 0.038
neuron differentiation GO:0030182 368 0.037
negative regulation of response to stimulus GO:0048585 155 0.037
protein phosphorylation GO:0006468 345 0.037
negative regulation of protein metabolic process GO:0051248 114 0.037
small gtpase mediated signal transduction GO:0007264 36 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
negative regulation of cellular protein metabolic process GO:0032269 106 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
regulation of phosphorylation GO:0042325 248 0.035
Human
transmembrane transport GO:0055085 412 0.035
regulation of protein modification process GO:0031399 194 0.034
Human
sexual reproduction GO:0019953 148 0.034
single organism biosynthetic process GO:0044711 342 0.033
cellular amine metabolic process GO:0044106 38 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
organic substance catabolic process GO:1901575 316 0.032
rna metabolic process GO:0016070 406 0.032
regulation of rna biosynthetic process GO:2001141 381 0.031
neuron projection development GO:0031175 273 0.031
cellular ketone metabolic process GO:0042180 51 0.031
negative regulation of nucleic acid templated transcription GO:1903507 117 0.031
cellular catabolic process GO:0044248 295 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
amine metabolic process GO:0009308 38 0.031
organic acid metabolic process GO:0006082 292 0.031
single organism catabolic process GO:0044712 283 0.031
response to organophosphorus GO:0046683 102 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
cell projection organization GO:0030030 302 0.030
regulation of nervous system development GO:0051960 264 0.029
lipid metabolic process GO:0006629 283 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
protein transport GO:0015031 132 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
intracellular signal transduction GO:0035556 314 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
single organism reproductive process GO:0044702 297 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
wound healing GO:0042060 122 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
regulation of neuron differentiation GO:0045664 208 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
alpha amino acid metabolic process GO:1901605 71 0.027
central nervous system development GO:0007417 311 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
positive regulation of developmental process GO:0051094 283 0.026
ras protein signal transduction GO:0007265 29 0.025
regulation of catalytic activity GO:0050790 304 0.025
behavior GO:0007610 205 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
response to acid chemical GO:0001101 222 0.025
ion transmembrane transport GO:0034220 365 0.024
oxoacid metabolic process GO:0043436 290 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.024
regulation of kinase activity GO:0043549 117 0.024
reproduction GO:0000003 245 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
negative regulation of programmed cell death GO:0043069 183 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
regulation of programmed cell death GO:0043067 341 0.023
neuron development GO:0048666 286 0.023
regulation of neuron projection development GO:0010975 161 0.023
regulation of cellular component organization GO:0051128 368 0.022
negative regulation of phosphate metabolic process GO:0045936 80 0.022
Human
epithelium development GO:0060429 96 0.022
brain development GO:0007420 247 0.022
macromolecule localization GO:0033036 252 0.022
protein localization GO:0008104 191 0.021
regulation of neuron death GO:1901214 115 0.021
multicellular organism reproduction GO:0032504 233 0.021
reactive oxygen species metabolic process GO:0072593 37 0.021
oxidation reduction process GO:0055114 304 0.021
regulation of cell differentiation GO:0045595 320 0.021
regulation of catabolic process GO:0009894 113 0.021
regulation of cell development GO:0060284 263 0.020
tissue development GO:0009888 252 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
response to carbohydrate GO:0009743 183 0.020
positive regulation of gene expression GO:0010628 244 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
protein oligomerization GO:0051259 191 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
negative regulation of molecular function GO:0044092 133 0.019
response to glucose GO:0009749 136 0.019
secretion GO:0046903 307 0.019
response to reactive oxygen species GO:0000302 120 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
multi organism reproductive process GO:0044703 262 0.019
response to metal ion GO:0010038 253 0.019
negative regulation of rna metabolic process GO:0051253 123 0.018
multicellular organismal reproductive process GO:0048609 233 0.017
response to temperature stimulus GO:0009266 94 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
head development GO:0060322 247 0.017
regulation of neurogenesis GO:0050767 247 0.017
response to ethanol GO:0045471 162 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
Human
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
aromatic compound catabolic process GO:0019439 168 0.017
response to inorganic substance GO:0010035 377 0.017
positive regulation of cell communication GO:0010647 271 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to wounding GO:0009611 254 0.017
apoptotic process GO:0006915 381 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
intracellular transport GO:0046907 185 0.017
regulation of protein kinase activity GO:0045859 105 0.017
gastrulation GO:0007369 2 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
dephosphorylation GO:0016311 98 0.016
Human
inorganic ion transmembrane transport GO:0098660 229 0.016
organophosphate catabolic process GO:0046434 148 0.016
purine containing compound metabolic process GO:0072521 253 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
heterocycle catabolic process GO:0046700 167 0.016
organelle organization GO:0006996 266 0.016
Human
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
chemosensory behavior GO:0007635 2 0.016
response to purine containing compound GO:0014074 126 0.016
cellular component movement GO:0006928 248 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
regulation of response to stress GO:0080134 126 0.016
response to hydrogen peroxide GO:0042542 89 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
gland development GO:0048732 155 0.016
peptidyl amino acid modification GO:0018193 126 0.016
response to external biotic stimulus GO:0043207 221 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
response to camp GO:0051591 91 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
Human
carbohydrate derivative catabolic process GO:1901136 147 0.015
negative regulation of cell communication GO:0010648 158 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
female pregnancy GO:0007565 122 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of small gtpase mediated signal transduction GO:0051056 48 0.015
positive regulation of secretion GO:0051047 140 0.015
carbohydrate metabolic process GO:0005975 130 0.015
negative regulation of phosphorylation GO:0042326 57 0.015
Human
negative regulation of protein phosphorylation GO:0001933 44 0.015
neuromuscular process GO:0050905 2 0.015
cell cell signaling GO:0007267 335 0.015
response to hexose GO:0009746 144 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
response to hypoxia GO:0001666 231 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
maintenance of location GO:0051235 17 0.014
developmental growth GO:0048589 100 0.014
response to oxidative stress GO:0006979 186 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
cation transmembrane transport GO:0098655 263 0.014
negative regulation of intracellular signal transduction GO:1902532 38 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
response to decreased oxygen levels GO:0036293 237 0.014
regulation of protein transport GO:0051223 68 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
muscle tissue development GO:0060537 58 0.014
dna metabolic process GO:0006259 96 0.013
single organism organelle organization GO:1902589 180 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
growth GO:0040007 165 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to light stimulus GO:0009416 52 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
salivary gland development GO:0007431 3 0.013
negative regulation of signaling GO:0023057 157 0.013
cofactor metabolic process GO:0051186 95 0.013
response to ketone GO:1901654 182 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
regulation of protein localization GO:0032880 81 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
gamete generation GO:0007276 124 0.013
positive regulation of cell death GO:0010942 184 0.013
negative regulation of cell death GO:0060548 229 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of mapk cascade GO:0043408 116 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
motor neuron axon guidance GO:0008045 1 0.013
sex differentiation GO:0007548 113 0.013
gonad development GO:0008406 104 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
cellular homeostasis GO:0019725 252 0.012
axis specification GO:0009798 4 0.012
positive regulation of cell development GO:0010720 176 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
chemical homeostasis GO:0048878 292 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of transmembrane transport GO:0034762 122 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
camera type eye morphogenesis GO:0048593 2 0.012
appendage morphogenesis GO:0035107 4 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
locomotion GO:0040011 237 0.012
hepaticobiliary system development GO:0061008 90 0.012
establishment of protein localization GO:0045184 141 0.012
blood circulation GO:0008015 183 0.011
regulation of cell proliferation GO:0042127 359 0.011
response to other organism GO:0051707 220 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
single organism intracellular transport GO:1902582 166 0.011
neuronal action potential GO:0019228 35 0.011
cation transport GO:0006812 382 0.011
nucleotide metabolic process GO:0009117 279 0.011
axon development GO:0061564 96 0.011
gtp metabolic process GO:0046039 72 0.011
regulation of growth GO:0040008 105 0.011
response to growth factor GO:0070848 189 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
response to biotic stimulus GO:0009607 226 0.011
positive regulation of molecular function GO:0044093 230 0.011
organ formation GO:0048645 3 0.011
proteolysis GO:0006508 175 0.011
response to radiation GO:0009314 137 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
regulation of intracellular transport GO:0032386 65 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
protein heterooligomerization GO:0051291 89 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
jak stat cascade GO:0007259 26 0.011
metal ion transport GO:0030001 289 0.011
peptide transport GO:0015833 97 0.011
positive regulation of catabolic process GO:0009896 78 0.011
vesicle mediated transport GO:0016192 181 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
Human
regulation of transferase activity GO:0051338 123 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
positive regulation of protein modification process GO:0031401 142 0.011
Human
neurological system process GO:0050877 219 0.011
purine containing compound catabolic process GO:0072523 138 0.011
nitrogen compound transport GO:0071705 229 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
regulation of establishment of protein localization GO:0070201 69 0.010
eye morphogenesis GO:0048592 4 0.010
neuron death GO:0070997 127 0.010
response to estrogen GO:0043627 232 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
response to monosaccharide GO:0034284 159 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
insulin secretion GO:0030073 69 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
cellular macromolecule localization GO:0070727 122 0.010
peptide hormone secretion GO:0030072 84 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
transmission of nerve impulse GO:0019226 42 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
cardiovascular system development GO:0072358 134 0.010
response to nutrient levels GO:0031667 370 0.010
male gamete generation GO:0048232 99 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010

Ankle2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.013
cardiovascular system disease DOID:1287 0 0.011
disease of metabolism DOID:0014667 0 0.010