Rattus norvegicus

0 known processes

Rps6ka2

ribosomal protein S6 kinase polypeptide 2

Rps6ka2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.115
positive regulation of phosphate metabolic process GO:0045937 262 0.107
ion transmembrane transport GO:0034220 365 0.101
cation transport GO:0006812 382 0.096
membrane repolarization GO:0086009 1 0.087
membrane depolarization during action potential GO:0086010 1 0.071
regulation of cellular localization GO:0060341 263 0.068
regulation of phosphate metabolic process GO:0019220 349 0.067
regulation of catalytic activity GO:0050790 304 0.059
oxoacid metabolic process GO:0043436 290 0.059
regulation of cellular component organization GO:0051128 368 0.059
Mouse
chemical homeostasis GO:0048878 292 0.059
regulation of molecular function GO:0065009 398 0.059
neuron development GO:0048666 286 0.054
cell cell signaling GO:0007267 335 0.052
homeostatic process GO:0042592 331 0.051
positive regulation of transport GO:0051050 245 0.049
inorganic ion transmembrane transport GO:0098660 229 0.048
g protein coupled receptor signaling pathway GO:0007186 242 0.048
secretion GO:0046903 307 0.048
cardiac conduction GO:0061337 2 0.048
response to extracellular stimulus GO:0009991 380 0.047
protein complex subunit organization GO:0071822 302 0.046
nucleic acid templated transcription GO:0097659 379 0.046
metal ion transport GO:0030001 289 0.045
positive regulation of molecular function GO:0044093 230 0.045
cellular component assembly GO:0022607 360 0.045
organic acid metabolic process GO:0006082 292 0.044
macromolecule localization GO:0033036 252 0.044
multicellular organismal signaling GO:0035637 44 0.044
protein complex biogenesis GO:0070271 263 0.042
macromolecular complex subunit organization GO:0043933 339 0.042
central nervous system development GO:0007417 311 0.041
cellular amine metabolic process GO:0044106 38 0.040
protein complex assembly GO:0006461 263 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.039
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
actin filament based process GO:0030029 86 0.039
regulation of membrane repolarization GO:0060306 1 0.038
cellular component biogenesis GO:0044085 368 0.038
heart contraction GO:0060047 57 0.037
Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
negative regulation of metabolic process GO:0009892 331 0.036
regulation of signal transduction GO:0009966 318 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.036
cell communication involved in cardiac conduction GO:0086065 2 0.035
cation transmembrane transport GO:0098655 263 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
synaptic transmission GO:0007268 235 0.034
cell projection organization GO:0030030 302 0.034
regulation of ion transport GO:0043269 245 0.033
neuron differentiation GO:0030182 368 0.033
nucleoside phosphate metabolic process GO:0006753 283 0.032
heterocycle catabolic process GO:0046700 167 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
behavior GO:0007610 205 0.032
purine nucleotide metabolic process GO:0006163 229 0.032
protein localization GO:0008104 191 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
regulation of heart contraction GO:0008016 48 0.031
organic anion transport GO:0015711 132 0.031
monovalent inorganic cation transport GO:0015672 172 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
rna metabolic process GO:0016070 406 0.029
neuron projection development GO:0031175 273 0.029
sensory perception GO:0007600 101 0.029
regulation of neuron differentiation GO:0045664 208 0.029
muscle system process GO:0003012 115 0.029
response to inorganic substance GO:0010035 377 0.029
regulation of cellular component movement GO:0051270 150 0.029
transcription dna templated GO:0006351 377 0.029
regulation of membrane potential GO:0042391 110 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
purine ribonucleotide metabolic process GO:0009150 227 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.027
cardiac muscle cell contraction GO:0086003 10 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
secretion by cell GO:0032940 248 0.027
regulation of phosphorylation GO:0042325 248 0.027
cellular homeostasis GO:0019725 252 0.026
regulation of transcription dna templated GO:0006355 374 0.026
anion transport GO:0006820 178 0.026
regulation of ion transmembrane transport GO:0034765 121 0.025
aromatic compound catabolic process GO:0019439 168 0.025
cellular cation homeostasis GO:0030003 180 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
positive regulation of nervous system development GO:0051962 178 0.024
protein transport GO:0015031 132 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of neurogenesis GO:0050767 247 0.024
positive regulation of cell development GO:0010720 176 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
cellular protein localization GO:0034613 122 0.023
cell morphogenesis GO:0000902 142 0.023
organic substance catabolic process GO:1901575 316 0.023
action potential GO:0001508 54 0.023
head development GO:0060322 247 0.023
catabolic process GO:0009056 351 0.023
response to nutrient levels GO:0031667 370 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.022
protein phosphorylation GO:0006468 345 0.022
Human Mouse
organophosphate metabolic process GO:0019637 370 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
nucleotide metabolic process GO:0009117 279 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
regulation of blood circulation GO:1903522 110 0.022
blood circulation GO:0008015 183 0.022
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.021
purine containing compound metabolic process GO:0072521 253 0.021
cation homeostasis GO:0055080 195 0.021
cellular chemical homeostasis GO:0055082 247 0.021
organelle organization GO:0006996 266 0.021
Mouse
nucleotide biosynthetic process GO:0009165 98 0.021
purine ribonucleotide biosynthetic process GO:0009152 81 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
regulation of response to external stimulus GO:0032101 106 0.021
cell cycle process GO:0022402 57 0.021
Mouse
organic cyclic compound catabolic process GO:1901361 175 0.021
positive regulation of gene expression GO:0010628 244 0.020
Mouse
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
regulation of secretion GO:0051046 224 0.020
metal ion homeostasis GO:0055065 186 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
regulation of cell development GO:0060284 263 0.020
regulation of cell projection organization GO:0031344 175 0.020
neurological system process GO:0050877 219 0.020
Mouse
positive regulation of ion transport GO:0043270 94 0.020
cellular ketone metabolic process GO:0042180 51 0.020
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.019
purine containing compound biosynthetic process GO:0072522 85 0.019
ras protein signal transduction GO:0007265 29 0.019
lipid metabolic process GO:0006629 283 0.019
synapse organization GO:0050808 46 0.019
negative regulation of gene expression GO:0010629 199 0.019
peptide transport GO:0015833 97 0.019
adult locomotory behavior GO:0008344 4 0.019
macromolecule catabolic process GO:0009057 58 0.019
nitrogen compound transport GO:0071705 229 0.019
rna biosynthetic process GO:0032774 380 0.019
regulation of rna metabolic process GO:0051252 391 0.019
brain development GO:0007420 247 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
regulation of secretion by cell GO:1903530 208 0.019
apoptotic process GO:0006915 381 0.019
Human Mouse
amine metabolic process GO:0009308 38 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of signaling GO:0023056 270 0.018
regulation of programmed cell death GO:0043067 341 0.018
Human
nucleobase containing compound catabolic process GO:0034655 152 0.018
cardiac muscle contraction GO:0060048 27 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
protein heterooligomerization GO:0051291 89 0.018
negative regulation of transport GO:0051051 136 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
single organism behavior GO:0044708 130 0.018
regulation of cell differentiation GO:0045595 320 0.018
regulation of synaptic transmission GO:0050804 141 0.018
divalent inorganic cation transport GO:0072511 134 0.018
regulation of protein metabolic process GO:0051246 289 0.018
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
regulation of protein localization GO:0032880 81 0.018
positive regulation of protein metabolic process GO:0051247 178 0.017
regulation of catabolic process GO:0009894 113 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
establishment of protein localization GO:0045184 141 0.017
single organism membrane organization GO:0044802 74 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
regulation of apoptotic process GO:0042981 335 0.017
Human
ion homeostasis GO:0050801 212 0.017
response to glucose GO:0009749 136 0.017
protein oligomerization GO:0051259 191 0.017
vesicle mediated transport GO:0016192 181 0.017
cellular catabolic process GO:0044248 295 0.017
intracellular transport GO:0046907 185 0.017
regulation of hydrolase activity GO:0051336 143 0.017
regulation of mapk cascade GO:0043408 116 0.016
ribonucleotide biosynthetic process GO:0009260 85 0.016
regulation of hormone levels GO:0010817 187 0.016
neuronal action potential GO:0019228 35 0.016
regulation of growth GO:0040008 105 0.016
regulation of transmembrane transport GO:0034762 122 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
single organism catabolic process GO:0044712 283 0.016
cell growth GO:0016049 104 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
nucleoside metabolic process GO:0009116 179 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
proteolysis GO:0006508 175 0.015
mapk cascade GO:0000165 140 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
negative regulation of cell death GO:0060548 229 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
purine containing compound catabolic process GO:0072523 138 0.015
regulation of neuron projection development GO:0010975 161 0.015
organic hydroxy compound transport GO:0015850 77 0.015
inorganic cation transmembrane transport GO:0098662 202 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
signal release GO:0023061 145 0.015
regulation of protein modification process GO:0031399 194 0.015
cellular component morphogenesis GO:0032989 155 0.015
purine nucleotide biosynthetic process GO:0006164 83 0.015
axis specification GO:0009798 4 0.015
regulation of protein transport GO:0051223 68 0.015
reproductive system development GO:0061458 128 0.015
cellular macromolecule localization GO:0070727 122 0.015
regulation of cell proliferation GO:0042127 359 0.015
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
positive regulation of signal transduction GO:0009967 175 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
chemosensory behavior GO:0007635 2 0.014
positive regulation of transcription factor import into nucleus GO:0042993 4 0.014
cellular response to external stimulus GO:0071496 118 0.014
eye morphogenesis GO:0048592 4 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
response to peptide GO:1901652 292 0.014
response to decreased oxygen levels GO:0036293 237 0.014
positive regulation of secretion GO:0051047 140 0.014
carboxylic acid transport GO:0046942 115 0.014
regulation of muscle system process GO:0090257 79 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
positive regulation of cell communication GO:0010647 271 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
negative regulation of cell communication GO:0010648 158 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
reproduction GO:0000003 245 0.014
Mouse
positive regulation of cell death GO:0010942 184 0.014
Human
regulation of system process GO:0044057 208 0.014
response to glucocorticoid GO:0051384 223 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
Human
actin cytoskeleton organization GO:0030036 73 0.013
anterior posterior pattern specification GO:0009952 1 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
cellular response to oxygen containing compound GO:1901701 386 0.013
Mouse
intracellular protein transport GO:0006886 79 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
response to reactive oxygen species GO:0000302 120 0.013
hormone transport GO:0009914 121 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
cell type specific apoptotic process GO:0097285 134 0.013
Mouse
heart morphogenesis GO:0003007 3 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
divalent metal ion transport GO:0070838 132 0.012
positive regulation of developmental process GO:0051094 283 0.012
cell cycle GO:0007049 101 0.012
Human Mouse
single organism cellular localization GO:1902580 102 0.012
nucleoside catabolic process GO:0009164 126 0.012
growth GO:0040007 165 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
grooming behavior GO:0007625 4 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
response to growth factor GO:0070848 189 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
hormone secretion GO:0046879 115 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
developmental growth GO:0048589 100 0.012
programmed cell death GO:0012501 392 0.012
Human Mouse
intracellular signal transduction GO:0035556 314 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
regulation of behavior GO:0050795 61 0.012
sensory perception of pain GO:0019233 73 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
response to mechanical stimulus GO:0009612 134 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.011
lipid transport GO:0006869 61 0.011
cytoplasmic transport GO:0016482 115 0.011
actin filament based movement GO:0030048 16 0.011
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.011
locomotion GO:0040011 237 0.011
response to oxygen levels GO:0070482 265 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
organic acid transport GO:0015849 116 0.011
response to metal ion GO:0010038 253 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
regulation of body fluid levels GO:0050878 90 0.011
respiratory gaseous exchange GO:0007585 4 0.011
camera type eye morphogenesis GO:0048593 2 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
Mouse
response to toxic substance GO:0009636 133 0.011
response to oxidative stress GO:0006979 186 0.011
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.011
positive regulation of protein modification process GO:0031401 142 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
reproductive process GO:0022414 372 0.011
Mouse
sexual reproduction GO:0019953 148 0.011
Mouse
response to estrogen GO:0043627 232 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
liver development GO:0001889 90 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of transferase activity GO:0051338 123 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
regulation of actin filament based movement GO:1903115 12 0.011
regulation of protein kinase activity GO:0045859 105 0.011
protein targeting GO:0006605 61 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
circulatory system process GO:0003013 183 0.011
Mouse
nucleoside triphosphate metabolic process GO:0009141 144 0.011
monocarboxylic acid transport GO:0015718 52 0.011
camp biosynthetic process GO:0006171 47 0.011
positive regulation of transferase activity GO:0051347 81 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
protein autophosphorylation GO:0046777 66 0.011
muscle structure development GO:0061061 87 0.011
regulation of respiratory gaseous exchange GO:0043576 2 0.011
neuron projection morphogenesis GO:0048812 122 0.010
positive regulation of kinase activity GO:0033674 77 0.010
oxidation reduction process GO:0055114 304 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
sequestering of calcium ion GO:0051208 8 0.010
calcium ion homeostasis GO:0055074 162 0.010
transmission of nerve impulse GO:0019226 42 0.010
regulation of homotypic cell cell adhesion GO:0034110 4 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
single organism organelle organization GO:1902589 180 0.010
single organism intracellular transport GO:1902582 166 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.010
spermatogenesis GO:0007283 99 0.010
response to radiation GO:0009314 137 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
response to monosaccharide GO:0034284 159 0.010

Rps6ka2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
kidney disease DOID:557 0 0.017
urinary system disease DOID:18 0 0.017
sensory system disease DOID:0050155 0 0.016
retinal disease DOID:5679 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
disease of metabolism DOID:0014667 0 0.013
long qt syndrome DOID:2843 0 0.011