Rattus norvegicus

8 known processes

Comp

cartilage oligomeric matrix protein

Comp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue development GO:0009888 252 0.165
cellular response to endogenous stimulus GO:0071495 377 0.123
metal ion transport GO:0030001 289 0.107
anatomical structure morphogenesis GO:0009653 298 0.105
cation transmembrane transport GO:0098655 263 0.104
regulation of rna metabolic process GO:0051252 391 0.094
cation transport GO:0006812 382 0.086
reproductive process GO:0022414 372 0.073
regulation of nucleic acid templated transcription GO:1903506 380 0.070
nucleic acid templated transcription GO:0097659 379 0.069
transcription dna templated GO:0006351 377 0.068
regulation of cell proliferation GO:0042127 359 0.067
aging GO:0007568 241 0.067
response to inorganic substance GO:0010035 377 0.066
regulation of phosphate metabolic process GO:0019220 349 0.065
rna metabolic process GO:0016070 406 0.064
regulation of transcription dna templated GO:0006355 374 0.061
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.059
response to nutrient GO:0007584 248 0.059
single organism biosynthetic process GO:0044711 342 0.057
organic acid metabolic process GO:0006082 292 0.057
regulation of multicellular organismal development GO:2000026 376 0.057
response to metal ion GO:0010038 253 0.056
oxoacid metabolic process GO:0043436 290 0.056
cell motility GO:0048870 202 0.054
transmembrane transport GO:0055085 412 0.053
positive regulation of multicellular organismal process GO:0051240 387 0.051
rna biosynthetic process GO:0032774 380 0.051
ion homeostasis GO:0050801 212 0.051
neuron differentiation GO:0030182 368 0.051
regulation of metal ion transport GO:0010959 118 0.050
ion transmembrane transport GO:0034220 365 0.049
regulation of molecular function GO:0065009 398 0.048
organophosphate metabolic process GO:0019637 370 0.048
regulation of programmed cell death GO:0043067 341 0.047
cellular response to oxygen containing compound GO:1901701 386 0.047
homeostatic process GO:0042592 331 0.047
regulation of phosphorylation GO:0042325 248 0.046
response to biotic stimulus GO:0009607 226 0.046
neuron projection development GO:0031175 273 0.046
positive regulation of cell proliferation GO:0008284 249 0.046
cellular cation homeostasis GO:0030003 180 0.046
intracellular signal transduction GO:0035556 314 0.045
regulation of ion transport GO:0043269 245 0.045
single organism reproductive process GO:0044702 297 0.045
brain development GO:0007420 247 0.044
regulation of cell differentiation GO:0045595 320 0.044
positive regulation of gene expression GO:0010628 244 0.043
response to growth factor GO:0070848 189 0.043
response to extracellular stimulus GO:0009991 380 0.043
defense response GO:0006952 194 0.043
regulation of cell development GO:0060284 263 0.043
positive regulation of biosynthetic process GO:0009891 319 0.043
response to peptide GO:1901652 292 0.043
regulation of rna biosynthetic process GO:2001141 381 0.042
cellular ketone metabolic process GO:0042180 51 0.042
locomotion GO:0040011 237 0.041
positive regulation of transcription dna templated GO:0045893 197 0.041
cation homeostasis GO:0055080 195 0.041
chemical homeostasis GO:0048878 292 0.041
regulation of protein metabolic process GO:0051246 289 0.041
localization of cell GO:0051674 202 0.041
regulation of phosphorus metabolic process GO:0051174 349 0.040
protein phosphorylation GO:0006468 345 0.040
neuron development GO:0048666 286 0.039
regeneration GO:0031099 163 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.039
positive regulation of phosphorus metabolic process GO:0010562 262 0.039
regulation of nervous system development GO:0051960 264 0.038
negative regulation of metabolic process GO:0009892 331 0.038
cellular component movement GO:0006928 248 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.037
cell growth GO:0016049 104 0.037
regulation of cellular component movement GO:0051270 150 0.036
cellular calcium ion homeostasis GO:0006874 160 0.036
response to estrogen GO:0043627 232 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
cellular component morphogenesis GO:0032989 155 0.036
positive regulation of developmental process GO:0051094 283 0.036
positive regulation of rna biosynthetic process GO:1902680 197 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
cell morphogenesis GO:0000902 142 0.035
cellular response to growth factor stimulus GO:0071363 162 0.035
head development GO:0060322 247 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
response to peptide hormone GO:0043434 278 0.034
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
enzyme linked receptor protein signaling pathway GO:0007167 116 0.034
response to cytokine GO:0034097 215 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
response to nutrient levels GO:0031667 370 0.033
positive regulation of response to stimulus GO:0048584 285 0.033
cellular metal ion homeostasis GO:0006875 172 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
positive regulation of cellular component movement GO:0051272 102 0.032
response to bacterium GO:0009617 200 0.032
negative regulation of apoptotic process GO:0043066 181 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.031
positive regulation of cell motility GO:2000147 97 0.031
inorganic cation transmembrane transport GO:0098662 202 0.031
cellular response to nitrogen compound GO:1901699 210 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
regulation of apoptotic process GO:0042981 335 0.030
multi organism reproductive process GO:0044703 262 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
response to acid chemical GO:0001101 222 0.030
monovalent inorganic cation transport GO:0015672 172 0.030
positive regulation of nervous system development GO:0051962 178 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
tissue regeneration GO:0042246 36 0.030
negative regulation of rna biosynthetic process GO:1902679 118 0.029
epithelium development GO:0060429 96 0.029
immune system process GO:0002376 204 0.029
organelle organization GO:0006996 266 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
secretion GO:0046903 307 0.029
cellular component assembly GO:0022607 360 0.028
regulation of cellular component organization GO:0051128 368 0.028
protein localization GO:0008104 191 0.028
catabolic process GO:0009056 351 0.028
regulation of neuron differentiation GO:0045664 208 0.028
response to external biotic stimulus GO:0043207 221 0.028
macromolecule localization GO:0033036 252 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
regulation of intracellular signal transduction GO:1902531 218 0.027
cellular response to abiotic stimulus GO:0071214 85 0.027
gastrulation GO:0007369 2 0.026
regulation of neurogenesis GO:0050767 247 0.026
membrane organization GO:0061024 94 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
organophosphate biosynthetic process GO:0090407 143 0.026
response to wounding GO:0009611 254 0.026
wound healing GO:0042060 122 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
response to other organism GO:0051707 220 0.025
tube development GO:0035295 89 0.025
divalent inorganic cation transport GO:0072511 134 0.024
negative regulation of biosynthetic process GO:0009890 168 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
regulation of catalytic activity GO:0050790 304 0.024
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
response to estradiol GO:0032355 164 0.024
cellular ion homeostasis GO:0006873 184 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
positive regulation of cell development GO:0010720 176 0.024
heart morphogenesis GO:0003007 3 0.024
growth GO:0040007 165 0.023
cellular chemical homeostasis GO:0055082 247 0.023
cellular lipid metabolic process GO:0044255 208 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
negative regulation of cell death GO:0060548 229 0.023
cellular amine metabolic process GO:0044106 38 0.023
muscle system process GO:0003012 115 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
regulation of cell migration GO:0030334 128 0.023
single organism membrane organization GO:0044802 74 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
positive regulation of cellular component organization GO:0051130 200 0.022
positive regulation of locomotion GO:0040017 102 0.022
cytosolic calcium ion homeostasis GO:0051480 140 0.022
regulation of homeostatic process GO:0032844 101 0.022
negative regulation of transcription dna templated GO:0045892 116 0.022
anatomical structure formation involved in morphogenesis GO:0048646 83 0.022
response to oxygen levels GO:0070482 265 0.022
cell projection organization GO:0030030 302 0.022
cellular response to lipid GO:0071396 201 0.022
cellular catabolic process GO:0044248 295 0.022
regulation of smooth muscle cell proliferation GO:0048660 75 0.022
cell migration GO:0016477 197 0.022
multicellular organism reproduction GO:0032504 233 0.022
nucleotide metabolic process GO:0009117 279 0.021
divalent metal ion transport GO:0070838 132 0.021
neuron projection morphogenesis GO:0048812 122 0.021
circulatory system development GO:0072359 134 0.021
negative regulation of gene expression GO:0010629 199 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
transmission of nerve impulse GO:0019226 42 0.021
sodium ion transmembrane transport GO:0035725 67 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
organic substance catabolic process GO:1901575 316 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
response to lipopolysaccharide GO:0032496 191 0.019
regulation of signal transduction GO:0009966 318 0.019
response to molecule of bacterial origin GO:0002237 194 0.019
response to glucocorticoid GO:0051384 223 0.019
organ induction GO:0001759 1 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of growth GO:0040008 105 0.019
amine metabolic process GO:0009308 38 0.019
single organism organelle organization GO:1902589 180 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
cellular response to stress GO:0033554 269 0.019
cell fate determination GO:0001709 2 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
central nervous system development GO:0007417 311 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
apoptotic process GO:0006915 381 0.018
response to corticosteroid GO:0031960 235 0.018
regulation of neuron projection development GO:0010975 161 0.018
positive regulation of cell migration GO:0030335 96 0.018
neuronal action potential GO:0019228 35 0.018
single organism intracellular transport GO:1902582 166 0.018
organ formation GO:0048645 3 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
protein complex biogenesis GO:0070271 263 0.018
axonogenesis GO:0007409 71 0.018
multicellular organismal signaling GO:0035637 44 0.018
small molecule biosynthetic process GO:0044283 124 0.018
intestinal absorption GO:0050892 3 0.018
proteolysis GO:0006508 175 0.018
response to vitamin GO:0033273 131 0.018
regulation of cell projection organization GO:0031344 175 0.017
regulation of calcium ion transport GO:0051924 77 0.017
regulation of immune system process GO:0002682 123 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
rhythmic process GO:0048511 156 0.017
cardiovascular system development GO:0072358 134 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
cell part morphogenesis GO:0032990 123 0.017
cellular component biogenesis GO:0044085 368 0.017
response to monosaccharide GO:0034284 159 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
cellular response to external stimulus GO:0071496 118 0.017
inflammatory response GO:0006954 150 0.017
protein complex subunit organization GO:0071822 302 0.017
formation of primary germ layer GO:0001704 1 0.017
neurological system process GO:0050877 219 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
programmed cell death GO:0012501 392 0.017
developmental process involved in reproduction GO:0003006 159 0.017
protein complex assembly GO:0006461 263 0.016
heterocycle catabolic process GO:0046700 167 0.016
gliogenesis GO:0042063 93 0.016
protein homooligomerization GO:0051260 91 0.016
positive regulation of cell death GO:0010942 184 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
immune response GO:0006955 104 0.016
sexual reproduction GO:0019953 148 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
negative regulation of molecular function GO:0044092 133 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
behavior GO:0007610 205 0.016
macromolecular complex assembly GO:0065003 273 0.016
response to oxidative stress GO:0006979 186 0.016
metal ion homeostasis GO:0055065 186 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
ribose phosphate metabolic process GO:0019693 235 0.015
mesoderm development GO:0007498 2 0.015
developmental induction GO:0031128 2 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
sodium ion transport GO:0006814 82 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
response to carbohydrate GO:0009743 183 0.015
positive regulation of molecular function GO:0044093 230 0.015
protein oligomerization GO:0051259 191 0.015
regulation of membrane potential GO:0042391 110 0.015
regulation of system process GO:0044057 208 0.014
single organism catabolic process GO:0044712 283 0.014
cellular homeostasis GO:0019725 252 0.014
positive regulation of immune system process GO:0002684 90 0.014
negative regulation of developmental process GO:0051093 125 0.014
axis specification GO:0009798 4 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
positive regulation of signaling GO:0023056 270 0.014
regulation of locomotion GO:0040012 148 0.014
lipid biosynthetic process GO:0008610 128 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
regulation of protein modification process GO:0031399 194 0.014
sensory organ development GO:0007423 74 0.014
biological adhesion GO:0022610 110 0.014
regulation of cell motility GO:2000145 131 0.014
cell adhesion GO:0007155 110 0.014
lymphocyte activation GO:0046649 43 0.014
action potential GO:0001508 54 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.013
response to decreased oxygen levels GO:0036293 237 0.013
positive regulation of protein modification process GO:0031401 142 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
secretion by cell GO:0032940 248 0.013
regulation of organ formation GO:0003156 2 0.013
cholesterol homeostasis GO:0042632 3 0.013
peptidyl amino acid modification GO:0018193 126 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
aromatic compound catabolic process GO:0019439 168 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
calcium ion transport GO:0006816 131 0.013
taxis GO:0042330 67 0.013
response to camp GO:0051591 91 0.013
establishment of protein localization GO:0045184 141 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.012
response to hypoxia GO:0001666 231 0.012
striated muscle tissue development GO:0014706 58 0.012
regulation of transmembrane transport GO:0034762 122 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
maintenance of location GO:0051235 17 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
reproductive structure development GO:0048608 128 0.012
cardiac muscle contraction GO:0060048 27 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
anterior posterior pattern specification GO:0009952 1 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
calcium ion homeostasis GO:0055074 162 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of hydrolase activity GO:0051336 143 0.012
epithelial cell proliferation GO:0050673 54 0.012
response to hexose GO:0009746 144 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of response to stress GO:0080134 126 0.012
carbohydrate metabolic process GO:0005975 130 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.011
regulation of cell growth GO:0001558 85 0.011
circulatory system process GO:0003013 183 0.011
organ morphogenesis GO:0009887 75 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
positive regulation of signal transduction GO:0009967 175 0.011
muscle cell proliferation GO:0033002 84 0.011
blood circulation GO:0008015 183 0.011
myelination GO:0042552 39 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
connective tissue development GO:0061448 33 0.011
intracellular transport GO:0046907 185 0.011
ras protein signal transduction GO:0007265 29 0.011
cellular response to peptide GO:1901653 133 0.011
purine containing compound catabolic process GO:0072523 138 0.011
regulation of anatomical structure size GO:0090066 135 0.011
hepaticobiliary system development GO:0061008 90 0.011
cellular response to acid chemical GO:0071229 75 0.011
response to purine containing compound GO:0014074 126 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
organic acid biosynthetic process GO:0016053 83 0.011
sequestering of calcium ion GO:0051208 8 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
camera type eye development GO:0043010 48 0.011
sequestering of metal ion GO:0051238 9 0.011
skeletal muscle organ development GO:0060538 33 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
cell cycle GO:0007049 101 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
reproductive system development GO:0061458 128 0.011
embryonic skeletal system development GO:0048706 3 0.011
digestive system development GO:0055123 41 0.011
anion transport GO:0006820 178 0.011
muscle structure development GO:0061061 87 0.011
leukocyte activation GO:0045321 76 0.011
regulation of response to wounding GO:1903034 69 0.011
oxidation reduction process GO:0055114 304 0.011
developmental growth GO:0048589 100 0.010
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.010
dna metabolic process GO:0006259 96 0.010
positive regulation of transferase activity GO:0051347 81 0.010
reproduction GO:0000003 245 0.010
regulation of hormone levels GO:0010817 187 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
eye morphogenesis GO:0048592 4 0.010
gamete generation GO:0007276 124 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
positive regulation of ion transport GO:0043270 94 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
eye development GO:0001654 50 0.010
regulation of synaptic transmission GO:0050804 141 0.010
acrosome assembly GO:0001675 3 0.010

Comp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.028
disease of metabolism DOID:0014667 0 0.016
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016