Rattus norvegicus

0 known processes

Lrrc68

leucine rich repeat containing 68

Lrrc68 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.097
regulation of catalytic activity GO:0050790 304 0.088
programmed cell death GO:0012501 392 0.069
rna metabolic process GO:0016070 406 0.066
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.063
negative regulation of biosynthetic process GO:0009890 168 0.062
regulation of molecular function GO:0065009 398 0.061
negative regulation of macromolecule metabolic process GO:0010605 260 0.059
cellular component assembly GO:0022607 360 0.059
cellular component biogenesis GO:0044085 368 0.057
negative regulation of metabolic process GO:0009892 331 0.055
regulation of phosphorus metabolic process GO:0051174 349 0.053
protein phosphorylation GO:0006468 345 0.053
intracellular signal transduction GO:0035556 314 0.053
nucleobase containing small molecule metabolic process GO:0055086 316 0.051
regulation of nucleic acid templated transcription GO:1903506 380 0.051
organophosphate metabolic process GO:0019637 370 0.050
negative regulation of cellular metabolic process GO:0031324 281 0.050
negative regulation of nucleic acid templated transcription GO:1903507 117 0.049
negative regulation of signaling GO:0023057 157 0.048
rna biosynthetic process GO:0032774 380 0.047
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.047
regulation of rna metabolic process GO:0051252 391 0.046
reproduction GO:0000003 245 0.045
regulation of transcription dna templated GO:0006355 374 0.044
regulation of multicellular organismal development GO:2000026 376 0.043
nucleic acid templated transcription GO:0097659 379 0.042
regulation of nervous system development GO:0051960 264 0.042
regulation of neuron projection development GO:0010975 161 0.041
regulation of signal transduction GO:0009966 318 0.041
purine nucleotide metabolic process GO:0006163 229 0.041
neuron differentiation GO:0030182 368 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.039
negative regulation of cellular biosynthetic process GO:0031327 161 0.038
apoptotic process GO:0006915 381 0.038
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.038
nucleotide metabolic process GO:0009117 279 0.038
regulation of rna biosynthetic process GO:2001141 381 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.037
regulation of cell development GO:0060284 263 0.037
negative regulation of rna biosynthetic process GO:1902679 118 0.037
cellular response to nitrogen compound GO:1901699 210 0.036
cell projection organization GO:0030030 302 0.036
negative regulation of gene expression GO:0010629 199 0.036
nucleoside metabolic process GO:0009116 179 0.035
positive regulation of developmental process GO:0051094 283 0.035
negative regulation of rna metabolic process GO:0051253 123 0.035
neuron projection development GO:0031175 273 0.034
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.034
regulation of phosphate metabolic process GO:0019220 349 0.034
single organism reproductive process GO:0044702 297 0.034
regulation of protein modification process GO:0031399 194 0.034
ribonucleotide metabolic process GO:0009259 231 0.034
regulation of cell projection organization GO:0031344 175 0.033
neuron development GO:0048666 286 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
regulation of phosphorylation GO:0042325 248 0.033
positive regulation of molecular function GO:0044093 230 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
transmembrane transport GO:0055085 412 0.033
multicellular organism reproduction GO:0032504 233 0.032
reproductive process GO:0022414 372 0.032
chemical homeostasis GO:0048878 292 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
single organism biosynthetic process GO:0044711 342 0.032
ribose phosphate metabolic process GO:0019693 235 0.032
regulation of cell proliferation GO:0042127 359 0.031
cellular ketone metabolic process GO:0042180 51 0.031
cellular amine metabolic process GO:0044106 38 0.031
positive regulation of cell communication GO:0010647 271 0.031
response to inorganic substance GO:0010035 377 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
regulation of apoptotic process GO:0042981 335 0.031
positive regulation of protein modification process GO:0031401 142 0.031
small gtpase mediated signal transduction GO:0007264 36 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.031
cell cell signaling GO:0007267 335 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
single organism organelle organization GO:1902589 180 0.030
macromolecular complex assembly GO:0065003 273 0.030
regulation of anatomical structure morphogenesis GO:0022603 141 0.030
rhythmic process GO:0048511 156 0.030
organic cyclic compound catabolic process GO:1901361 175 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
homeostatic process GO:0042592 331 0.030
regulation of protein metabolic process GO:0051246 289 0.029
cellular homeostasis GO:0019725 252 0.029
amine metabolic process GO:0009308 38 0.029
heterocycle catabolic process GO:0046700 167 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
response to nutrient levels GO:0031667 370 0.029
regulation of neuron differentiation GO:0045664 208 0.029
purine ribonucleotide metabolic process GO:0009150 227 0.028
ras protein signal transduction GO:0007265 29 0.028
cation transport GO:0006812 382 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
negative regulation of protein import into nucleus translocation GO:0033159 1 0.028
positive regulation of cell development GO:0010720 176 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
central nervous system development GO:0007417 311 0.027
protein complex subunit organization GO:0071822 302 0.027
response to carbohydrate GO:0009743 183 0.027
synaptic transmission GO:0007268 235 0.027
negative regulation of cell communication GO:0010648 158 0.027
growth GO:0040007 165 0.027
developmental process involved in reproduction GO:0003006 159 0.027
negative regulation of protein metabolic process GO:0051248 114 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
purine containing compound catabolic process GO:0072523 138 0.026
positive regulation of nervous system development GO:0051962 178 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
dephosphorylation GO:0016311 98 0.025
learning or memory GO:0007611 90 0.025
positive regulation of neuron differentiation GO:0045666 126 0.025
catabolic process GO:0009056 351 0.025
regulation of cell differentiation GO:0045595 320 0.025
regulation of neurogenesis GO:0050767 247 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
regulation of cellular component organization GO:0051128 368 0.025
ion transmembrane transport GO:0034220 365 0.025
regulation of membrane potential GO:0042391 110 0.025
lipid metabolic process GO:0006629 283 0.025
regulation of protein kinase activity GO:0045859 105 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
multi organism reproductive process GO:0044703 262 0.024
cell part morphogenesis GO:0032990 123 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of hydrolase activity GO:0051336 143 0.024
multi multicellular organism process GO:0044706 138 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
protein complex assembly GO:0006461 263 0.024
negative regulation of cell proliferation GO:0008285 119 0.024
carboxylic acid metabolic process GO:0019752 289 0.023
organelle organization GO:0006996 266 0.023
cognition GO:0050890 92 0.023
cellular catabolic process GO:0044248 295 0.023
neurological system process GO:0050877 219 0.023
organic acid metabolic process GO:0006082 292 0.023
oxoacid metabolic process GO:0043436 290 0.023
protein autophosphorylation GO:0046777 66 0.022
actin filament based process GO:0030029 86 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
regulation of ion transport GO:0043269 245 0.022
negative regulation of molecular function GO:0044092 133 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
response to metal ion GO:0010038 253 0.021
response to peptide GO:1901652 292 0.021
purine ribonucleoside catabolic process GO:0046130 124 0.021
metal ion transport GO:0030001 289 0.021
peptidyl amino acid modification GO:0018193 126 0.021
secretion GO:0046903 307 0.021
response to wounding GO:0009611 254 0.021
response to hexose GO:0009746 144 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
embryonic pattern specification GO:0009880 1 0.020
aging GO:0007568 241 0.020
response to monosaccharide GO:0034284 159 0.019
response to glucose GO:0009749 136 0.019
cell migration GO:0016477 197 0.019
cell projection morphogenesis GO:0048858 123 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
reproductive system development GO:0061458 128 0.019
sex differentiation GO:0007548 113 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
behavior GO:0007610 205 0.019
vesicle mediated transport GO:0016192 181 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
regulation of gtpase activity GO:0043087 57 0.019
brain development GO:0007420 247 0.019
protein localization GO:0008104 191 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
cellular response to stress GO:0033554 269 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
nucleotide catabolic process GO:0009166 139 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
single organism behavior GO:0044708 130 0.019
axon development GO:0061564 96 0.019
protein complex biogenesis GO:0070271 263 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
immune system process GO:0002376 204 0.018
macromolecule localization GO:0033036 252 0.018
reproductive structure development GO:0048608 128 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
action potential GO:0001508 54 0.018
regulation of anatomical structure size GO:0090066 135 0.018
response to acid chemical GO:0001101 222 0.018
organophosphate catabolic process GO:0046434 148 0.018
regulation of synaptic transmission GO:0050804 141 0.018
organic substance catabolic process GO:1901575 316 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
asymmetric protein localization GO:0008105 2 0.018
regulation of growth GO:0040008 105 0.018
gonad development GO:0008406 104 0.018
cell morphogenesis GO:0000902 142 0.018
cellular component movement GO:0006928 248 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
positive regulation of gene expression GO:0010628 244 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
response to extracellular stimulus GO:0009991 380 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
cellular lipid metabolic process GO:0044255 208 0.017
negative regulation of transport GO:0051051 136 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
cell motility GO:0048870 202 0.017
response to corticosteroid GO:0031960 235 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
intracellular transport GO:0046907 185 0.016
head development GO:0060322 247 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
regulation of activation of jak2 kinase activity GO:0010534 1 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
positive regulation of cellular component organization GO:0051130 200 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
positive regulation of signaling GO:0023056 270 0.015
response to nutrient GO:0007584 248 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
single organism catabolic process GO:0044712 283 0.015
regulation of programmed cell death GO:0043067 341 0.015
response to glucocorticoid GO:0051384 223 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of secretion GO:0051046 224 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
multicellular organism growth GO:0035264 1 0.015
cellular component morphogenesis GO:0032989 155 0.015
tissue development GO:0009888 252 0.015
actin cytoskeleton organization GO:0030036 73 0.015
response to decreased oxygen levels GO:0036293 237 0.015
response to insulin GO:0032868 133 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
lipid storage GO:0019915 1 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
response to oxygen levels GO:0070482 265 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
proteolysis GO:0006508 175 0.014
positive regulation of signal transduction GO:0009967 175 0.014
response to other organism GO:0051707 220 0.014
regulation of transmembrane transport GO:0034762 122 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
response to axon injury GO:0048678 59 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
rho protein signal transduction GO:0007266 11 0.014
multicellular organismal signaling GO:0035637 44 0.014
heart morphogenesis GO:0003007 3 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
locomotion GO:0040011 237 0.014
cellular chemical homeostasis GO:0055082 247 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
regulation of g0 to g1 transition GO:0070316 3 0.014
defense response GO:0006952 194 0.014
maintenance of location GO:0051235 17 0.014
aromatic compound catabolic process GO:0019439 168 0.014
olfactory behavior GO:0042048 2 0.014
cytoskeleton organization GO:0007010 111 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
positive regulation of phosphorylation GO:0042327 177 0.013
negative regulation of cell death GO:0060548 229 0.013
regulation of transferase activity GO:0051338 123 0.013
gastrulation GO:0007369 2 0.013
ion homeostasis GO:0050801 212 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
development of primary sexual characteristics GO:0045137 107 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
cardiovascular system development GO:0072358 134 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
response to external biotic stimulus GO:0043207 221 0.013
establishment of protein localization GO:0045184 141 0.013
response to ethanol GO:0045471 162 0.013
localization of cell GO:0051674 202 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
regulation of system process GO:0044057 208 0.013
cell type specific apoptotic process GO:0097285 134 0.013
response to estrogen GO:0043627 232 0.012
response to estradiol GO:0032355 164 0.012
regulation of kinase activity GO:0043549 117 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
cellular response to lipid GO:0071396 201 0.012
negative regulation of nervous system development GO:0051961 79 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of cellular localization GO:0060341 263 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
regulation of metal ion transport GO:0010959 118 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
response to peptide hormone GO:0043434 278 0.012
response to hypoxia GO:0001666 231 0.012
negative regulation of signal transduction GO:0009968 83 0.012
response to growth factor GO:0070848 189 0.012
protein oligomerization GO:0051259 191 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
sodium ion transport GO:0006814 82 0.012
circulatory system process GO:0003013 183 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
regulation of locomotion GO:0040012 148 0.012
muscle tissue development GO:0060537 58 0.012
female pregnancy GO:0007565 122 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
single organism cellular localization GO:1902580 102 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
transmission of nerve impulse GO:0019226 42 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
chemosensory behavior GO:0007635 2 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regeneration GO:0031099 163 0.011
somatic stem cell division GO:0048103 2 0.011
lipid biosynthetic process GO:0008610 128 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
response to oxidative stress GO:0006979 186 0.011
response to lipopolysaccharide GO:0032496 191 0.011
secretion by cell GO:0032940 248 0.011
negative regulation of innate immune response GO:0045824 4 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
single organism intracellular transport GO:1902582 166 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
axis specification GO:0009798 4 0.011
nucleoside catabolic process GO:0009164 126 0.011
anion transport GO:0006820 178 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of hormone levels GO:0010817 187 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
regulation of catabolic process GO:0009894 113 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
positive regulation of cell death GO:0010942 184 0.011
organic hydroxy compound transport GO:0015850 77 0.010
leukocyte differentiation GO:0002521 30 0.010
cellular response to peptide GO:1901653 133 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
regulation of sodium ion transport GO:0002028 21 0.010
regulation of transmembrane transporter activity GO:0022898 49 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
cellular response to acid chemical GO:0071229 75 0.010
cation transmembrane transport GO:0098655 263 0.010
neuronal action potential GO:0019228 35 0.010
cation homeostasis GO:0055080 195 0.010
nitrogen compound transport GO:0071705 229 0.010

Lrrc68 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.012