Rattus norvegicus

54 known processes

Dffb

DNA fragmentation factor, beta polypeptide (caspase-activated DNase)

(Aliases: Cad)

Dffb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.151
regulation of rna biosynthetic process GO:2001141 381 0.151
negative regulation of rna metabolic process GO:0051253 123 0.138
neuron differentiation GO:0030182 368 0.108
rna biosynthetic process GO:0032774 380 0.107
regulation of nucleic acid templated transcription GO:1903506 380 0.106
response to cytokine GO:0034097 215 0.098
regulation of rna metabolic process GO:0051252 391 0.092
reproductive structure development GO:0048608 128 0.077
rna metabolic process GO:0016070 406 0.077
response to other organism GO:0051707 220 0.072
cellular component movement GO:0006928 248 0.071
nucleic acid templated transcription GO:0097659 379 0.069
regulation of apoptotic process GO:0042981 335 0.069
anatomical structure morphogenesis GO:0009653 298 0.068
positive regulation of transcription dna templated GO:0045893 197 0.059
cellular component morphogenesis GO:0032989 155 0.053
cell migration GO:0016477 197 0.051
developmental process involved in reproduction GO:0003006 159 0.050
transcription dna templated GO:0006351 377 0.046
negative regulation of rna biosynthetic process GO:1902679 118 0.044
regulation of signal transduction GO:0009966 318 0.043
neuron development GO:0048666 286 0.042
cell part morphogenesis GO:0032990 123 0.041
regulation of mapk cascade GO:0043408 116 0.040
regulation of molecular function GO:0065009 398 0.040
cell motility GO:0048870 202 0.039
neuron projection morphogenesis GO:0048812 122 0.039
response to growth factor GO:0070848 189 0.038
regulation of cell projection organization GO:0031344 175 0.037
protein phosphorylation GO:0006468 345 0.037
positive regulation of locomotion GO:0040017 102 0.037
cellular response to growth factor stimulus GO:0071363 162 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
regulation of cell development GO:0060284 263 0.036
cellular amino acid metabolic process GO:0006520 107 0.033
glycosaminoglycan biosynthetic process GO:0006024 4 0.032
immune system process GO:0002376 204 0.032
response to oxidative stress GO:0006979 186 0.031
chemotaxis GO:0006935 66 0.030
gonad development GO:0008406 104 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
cell morphogenesis GO:0000902 142 0.029
organic acid metabolic process GO:0006082 292 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
response to nutrient levels GO:0031667 370 0.028
regulation of cell motility GO:2000145 131 0.028
chemical homeostasis GO:0048878 292 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of phosphorylation GO:0042325 248 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
programmed cell death GO:0012501 392 0.026
action potential GO:0001508 54 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
positive regulation of gene expression GO:0010628 244 0.025
regulation of programmed cell death GO:0043067 341 0.025
cell projection organization GO:0030030 302 0.024
regulation of nervous system development GO:0051960 264 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
inflammatory response GO:0006954 150 0.023
organophosphate metabolic process GO:0019637 370 0.023
locomotion GO:0040011 237 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
positive regulation of mapk cascade GO:0043410 92 0.023
mapk cascade GO:0000165 140 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
positive regulation of molecular function GO:0044093 230 0.023
regulation of phosphate metabolic process GO:0019220 349 0.022
cellular response to stress GO:0033554 269 0.022
development of primary sexual characteristics GO:0045137 107 0.021
protein oligomerization GO:0051259 191 0.021
protein autophosphorylation GO:0046777 66 0.021
regulation of response to stress GO:0080134 126 0.021
sex differentiation GO:0007548 113 0.021
regulation of immune system process GO:0002682 123 0.021
mechanoreceptor differentiation GO:0042490 2 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
regeneration GO:0031099 163 0.021
hair cell differentiation GO:0035315 2 0.021
hematopoietic progenitor cell differentiation GO:0002244 2 0.021
catabolic process GO:0009056 351 0.020
ear development GO:0043583 21 0.020
response to external biotic stimulus GO:0043207 221 0.020
anion transport GO:0006820 178 0.019
intracellular signal transduction GO:0035556 314 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
regulation of protein metabolic process GO:0051246 289 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
regulation of cell migration GO:0030334 128 0.019
macromolecular complex assembly GO:0065003 273 0.019
proteolysis GO:0006508 175 0.019
positive regulation of endothelial cell migration GO:0010595 4 0.018
cellular response to lipopolysaccharide GO:0071222 55 0.018
dna metabolic process GO:0006259 96 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
cellular amine metabolic process GO:0044106 38 0.018
carboxylic acid transport GO:0046942 115 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
positive regulation of cell migration GO:0030335 96 0.018
organ regeneration GO:0031100 101 0.018
lipid biosynthetic process GO:0008610 128 0.018
cytokine mediated signaling pathway GO:0019221 43 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of dna metabolic process GO:0051052 60 0.017
localization of cell GO:0051674 202 0.017
cell projection morphogenesis GO:0048858 123 0.017
secretion GO:0046903 307 0.017
embryonic skeletal system development GO:0048706 3 0.017
response to nutrient GO:0007584 248 0.017
spindle organization GO:0007051 2 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
multicellular organism reproduction GO:0032504 233 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
positive regulation of cell communication GO:0010647 271 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
regulation of neurogenesis GO:0050767 247 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
cellular response to oxidative stress GO:0034599 76 0.016
defense response to gram negative bacterium GO:0050829 3 0.016
peptidyl tyrosine modification GO:0018212 72 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
brain development GO:0007420 247 0.015
negative regulation of cell death GO:0060548 229 0.015
hematopoietic or lymphoid organ development GO:0048534 36 0.015
macromolecule catabolic process GO:0009057 58 0.015
apoptotic process GO:0006915 381 0.015
positive regulation of developmental process GO:0051094 283 0.015
intestinal absorption GO:0050892 3 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
response to lipopolysaccharide GO:0032496 191 0.015
regulation of immune response GO:0050776 55 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
anion transmembrane transport GO:0098656 77 0.015
response to bacterium GO:0009617 200 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
neuron projection development GO:0031175 273 0.014
regulation of neuron projection development GO:0010975 161 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
negative regulation of cell communication GO:0010648 158 0.014
response to reactive oxygen species GO:0000302 120 0.014
reproductive system development GO:0061458 128 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
amine metabolic process GO:0009308 38 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
cellular response to reactive oxygen species GO:0034614 55 0.014
response to extracellular stimulus GO:0009991 380 0.014
cell cycle GO:0007049 101 0.014
oxoacid metabolic process GO:0043436 290 0.014
regulation of catabolic process GO:0009894 113 0.014
negative regulation of innate immune response GO:0045824 4 0.014
response to wounding GO:0009611 254 0.014
ras protein signal transduction GO:0007265 29 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
lipid metabolic process GO:0006629 283 0.013
regulation of neuron differentiation GO:0045664 208 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
positive regulation of protein modification process GO:0031401 142 0.013
positive regulation of cell development GO:0010720 176 0.013
organic acid transport GO:0015849 116 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
axis specification GO:0009798 4 0.013
immune response GO:0006955 104 0.013
intracellular transport GO:0046907 185 0.013
regulation of catalytic activity GO:0050790 304 0.013
negative regulation of metabolic process GO:0009892 331 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 3 0.013
defense response GO:0006952 194 0.012
protein complex subunit organization GO:0071822 302 0.012
regulation of cell differentiation GO:0045595 320 0.012
response to peptide hormone GO:0043434 278 0.012
regulation of cell proliferation GO:0042127 359 0.012
protein complex biogenesis GO:0070271 263 0.012
response to hydrogen peroxide GO:0042542 89 0.012
cellular response to nutrient levels GO:0031669 60 0.012
inner ear receptor cell differentiation GO:0060113 2 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
cell type specific apoptotic process GO:0097285 134 0.012
axon development GO:0061564 96 0.012
bmp signaling pathway GO:0030509 4 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
negative regulation of apoptotic process GO:0043066 181 0.011
positive regulation of transferase activity GO:0051347 81 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
secretion by cell GO:0032940 248 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
neuronal action potential GO:0019228 35 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
cellular ketone metabolic process GO:0042180 51 0.011
reproductive process GO:0022414 372 0.011
ethanolamine containing compound metabolic process GO:0042439 14 0.011
protein processing GO:0016485 68 0.011
heart morphogenesis GO:0003007 3 0.011
lens fiber cell differentiation GO:0070306 3 0.011
peptide biosynthetic process GO:0043043 3 0.010
syncytium formation by plasma membrane fusion GO:0000768 3 0.010
lipid storage GO:0019915 1 0.010
defense response to gram positive bacterium GO:0050830 2 0.010
tolerance induction dependent upon immune response GO:0002461 2 0.010
regulation of secretion by cell GO:1903530 208 0.010
central nervous system development GO:0007417 311 0.010
organic anion transport GO:0015711 132 0.010
regulation of multicellular organismal development GO:2000026 376 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
follicle stimulating hormone signaling pathway GO:0042699 5 0.010
embryonic placenta development GO:0001892 1 0.010
lens development in camera type eye GO:0002088 13 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
vasculature development GO:0001944 70 0.010

Dffb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
disease of anatomical entity DOID:7 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011