Rattus norvegicus

22 known processes

Pi4kb

phosphatidylinositol 4-kinase, catalytic, beta

(Aliases: Pik4cb)

Pi4kb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.228
rna metabolic process GO:0016070 406 0.178
regulation of rna biosynthetic process GO:2001141 381 0.155
transcription dna templated GO:0006351 377 0.142
regulation of multicellular organismal development GO:2000026 376 0.135
regulation of nucleic acid templated transcription GO:1903506 380 0.135
rna biosynthetic process GO:0032774 380 0.128
transcription from rna polymerase ii promoter GO:0006366 252 0.124
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.104
single organism organelle organization GO:1902589 180 0.102
axon development GO:0061564 96 0.101
cellular response to hormone stimulus GO:0032870 247 0.098
nucleic acid templated transcription GO:0097659 379 0.098
locomotion GO:0040011 237 0.093
regulation of transcription dna templated GO:0006355 374 0.091
regulation of rna metabolic process GO:0051252 391 0.088
macromolecule localization GO:0033036 252 0.088
macromolecular complex subunit organization GO:0043933 339 0.085
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.084
positive regulation of nucleic acid templated transcription GO:1903508 197 0.082
positive regulation of biosynthetic process GO:0009891 319 0.078
regulation of cellular component organization GO:0051128 368 0.077
positive regulation of gene expression GO:0010628 244 0.076
neuron development GO:0048666 286 0.076
negative regulation of cellular metabolic process GO:0031324 281 0.076
negative regulation of metabolic process GO:0009892 331 0.073
positive regulation of rna biosynthetic process GO:1902680 197 0.071
reproductive process GO:0022414 372 0.071
positive regulation of cellular biosynthetic process GO:0031328 295 0.066
localization of cell GO:0051674 202 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.064
positive regulation of rna metabolic process GO:0051254 203 0.062
cellular response to endogenous stimulus GO:0071495 377 0.061
regulation of anatomical structure morphogenesis GO:0022603 141 0.060
cell projection organization GO:0030030 302 0.060
positive regulation of developmental process GO:0051094 283 0.059
neuron projection development GO:0031175 273 0.059
regulation of anatomical structure size GO:0090066 135 0.057
cellular component morphogenesis GO:0032989 155 0.056
positive regulation of transcription dna templated GO:0045893 197 0.055
regulation of nervous system development GO:0051960 264 0.052
negative regulation of nucleic acid templated transcription GO:1903507 117 0.052
organic acid metabolic process GO:0006082 292 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.049
cellular component movement GO:0006928 248 0.049
cellular component biogenesis GO:0044085 368 0.048
anatomical structure morphogenesis GO:0009653 298 0.048
intracellular signal transduction GO:0035556 314 0.047
macromolecular complex assembly GO:0065003 273 0.044
regulation of cell differentiation GO:0045595 320 0.044
organelle organization GO:0006996 266 0.044
multi organism reproductive process GO:0044703 262 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
cellular amino acid metabolic process GO:0006520 107 0.043
programmed cell death GO:0012501 392 0.042
protein transport GO:0015031 132 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.041
protein phosphorylation GO:0006468 345 0.041
response to other organism GO:0051707 220 0.041
cell motility GO:0048870 202 0.039
response to nutrient levels GO:0031667 370 0.039
cell migration GO:0016477 197 0.039
single organism reproductive process GO:0044702 297 0.038
regulation of protein phosphorylation GO:0001932 183 0.038
cell projection morphogenesis GO:0048858 123 0.038
neuron projection morphogenesis GO:0048812 122 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
regulation of catalytic activity GO:0050790 304 0.037
regulation of cell development GO:0060284 263 0.037
cellular response to stress GO:0033554 269 0.037
regulation of neuron differentiation GO:0045664 208 0.036
cellular ketone metabolic process GO:0042180 51 0.036
negative regulation of response to stimulus GO:0048585 155 0.036
negative regulation of cellular component organization GO:0051129 83 0.036
oxoacid metabolic process GO:0043436 290 0.036
amine metabolic process GO:0009308 38 0.035
regulation of programmed cell death GO:0043067 341 0.035
membrane organization GO:0061024 94 0.034
cellular amine metabolic process GO:0044106 38 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
protein localization GO:0008104 191 0.034
reproduction GO:0000003 245 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
central nervous system development GO:0007417 311 0.034
multicellular organism reproduction GO:0032504 233 0.033
cellular response to oxygen containing compound GO:1901701 386 0.032
growth GO:0040007 165 0.032
cell morphogenesis GO:0000902 142 0.032
regulation of neurogenesis GO:0050767 247 0.032
response to extracellular stimulus GO:0009991 380 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
secretion GO:0046903 307 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.031
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.031
heart morphogenesis GO:0003007 3 0.031
apoptotic process GO:0006915 381 0.031
purine nucleotide metabolic process GO:0006163 229 0.031
regulation of locomotion GO:0040012 148 0.031
regulation of apoptotic process GO:0042981 335 0.031
cellular response to organonitrogen compound GO:0071417 197 0.030
positive regulation of cell death GO:0010942 184 0.030
establishment of protein localization GO:0045184 141 0.030
cellular component assembly GO:0022607 360 0.030
regulation of growth GO:0040008 105 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
regulation of cell proliferation GO:0042127 359 0.029
developmental process involved in reproduction GO:0003006 159 0.029
response to external biotic stimulus GO:0043207 221 0.029
aging GO:0007568 241 0.029
regulation of cell projection organization GO:0031344 175 0.028
negative regulation of rna biosynthetic process GO:1902679 118 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
single organism biosynthetic process GO:0044711 342 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
actin cytoskeleton organization GO:0030036 73 0.028
cytoskeleton organization GO:0007010 111 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
positive regulation of signaling GO:0023056 270 0.027
tissue development GO:0009888 252 0.027
regulation of secretion by cell GO:1903530 208 0.027
response to monosaccharide GO:0034284 159 0.027
intracellular transport GO:0046907 185 0.027
response to decreased oxygen levels GO:0036293 237 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
cellular response to lipid GO:0071396 201 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
ras protein signal transduction GO:0007265 29 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
response to hypoxia GO:0001666 231 0.026
purine containing compound metabolic process GO:0072521 253 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
regulation of protein metabolic process GO:0051246 289 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
secretion by cell GO:0032940 248 0.025
regulation of axonogenesis GO:0050770 37 0.025
actin filament based process GO:0030029 86 0.025
response to acid chemical GO:0001101 222 0.025
regulation of phosphorylation GO:0042325 248 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
protein complex biogenesis GO:0070271 263 0.024
regulation of cell migration GO:0030334 128 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
developmental growth GO:0048589 100 0.024
protein complex assembly GO:0006461 263 0.024
response to peptide hormone GO:0043434 278 0.024
response to hexose GO:0009746 144 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
multi multicellular organism process GO:0044706 138 0.023
response to purine containing compound GO:0014074 126 0.023
circadian rhythm GO:0007623 88 0.023
regulation of protein modification process GO:0031399 194 0.023
regulation of organelle organization GO:0033043 80 0.023
response to oxygen levels GO:0070482 265 0.022
negative regulation of gene expression GO:0010629 199 0.022
negative regulation of neurogenesis GO:0050768 78 0.022
positive regulation of molecular function GO:0044093 230 0.022
catabolic process GO:0009056 351 0.022
head development GO:0060322 247 0.022
regulation of molecular function GO:0065009 398 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
heterocycle catabolic process GO:0046700 167 0.022
cellular homeostasis GO:0019725 252 0.022
regulation of cellular localization GO:0060341 263 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
chemical homeostasis GO:0048878 292 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
homeostatic process GO:0042592 331 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
negative regulation of cell development GO:0010721 82 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
response to growth factor GO:0070848 189 0.021
response to inorganic substance GO:0010035 377 0.021
cellular lipid metabolic process GO:0044255 208 0.021
response to glucose GO:0009749 136 0.021
response to bacterium GO:0009617 200 0.021
negative regulation of developmental process GO:0051093 125 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
purine containing compound catabolic process GO:0072523 138 0.020
protein complex subunit organization GO:0071822 302 0.020
cell growth GO:0016049 104 0.020
single organism cellular localization GO:1902580 102 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.020
response to radiation GO:0009314 137 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
cellular chemical homeostasis GO:0055082 247 0.019
cellular catabolic process GO:0044248 295 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
negative regulation of cell proliferation GO:0008285 119 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
response to biotic stimulus GO:0009607 226 0.019
cation transport GO:0006812 382 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
regulation of cell morphogenesis GO:0022604 77 0.019
response to corticosteroid GO:0031960 235 0.019
response to nutrient GO:0007584 248 0.019
response to peptide GO:1901652 292 0.019
cellular ion homeostasis GO:0006873 184 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
gliogenesis GO:0042063 93 0.018
single organism catabolic process GO:0044712 283 0.018
proteolysis GO:0006508 175 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
negative regulation of cell death GO:0060548 229 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
cellular macromolecule localization GO:0070727 122 0.018
cellular response to peptide GO:1901653 133 0.018
vesicle mediated transport GO:0016192 181 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
negative regulation of nervous system development GO:0051961 79 0.018
regulation of neuron projection development GO:0010975 161 0.018
positive regulation of transport GO:0051050 245 0.018
regulation of cell growth GO:0001558 85 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
cell type specific apoptotic process GO:0097285 134 0.018
negative regulation of signaling GO:0023057 157 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
lipid metabolic process GO:0006629 283 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of signal transduction GO:0009966 318 0.017
response to metal ion GO:0010038 253 0.017
cardiac chamber development GO:0003205 1 0.017
cytokine production GO:0001816 61 0.017
circulatory system process GO:0003013 183 0.017
response to carbohydrate GO:0009743 183 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
positive regulation of protein modification process GO:0031401 142 0.017
negative regulation of cell communication GO:0010648 158 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
regulation of establishment of protein localization GO:0070201 69 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
cell part morphogenesis GO:0032990 123 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
protein oligomerization GO:0051259 191 0.016
chromatin organization GO:0006325 34 0.016
protein secretion GO:0009306 34 0.016
axonogenesis GO:0007409 71 0.016
biological adhesion GO:0022610 110 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
intracellular protein transport GO:0006886 79 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
regulation of secretion GO:0051046 224 0.016
protein autophosphorylation GO:0046777 66 0.016
rhythmic process GO:0048511 156 0.016
nucleoside metabolic process GO:0009116 179 0.016
response to wounding GO:0009611 254 0.016
cytoskeleton dependent cytokinesis GO:0061640 2 0.016
positive regulation of cell development GO:0010720 176 0.016
regulation of protein localization GO:0032880 81 0.016
chromatin modification GO:0016568 33 0.016
nucleotide catabolic process GO:0009166 139 0.016
meiotic cell cycle process GO:1903046 3 0.016
response to ethanol GO:0045471 162 0.016
single organism intracellular transport GO:1902582 166 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
cation homeostasis GO:0055080 195 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
sexual reproduction GO:0019953 148 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
cellular amide metabolic process GO:0043603 44 0.015
regulation of catabolic process GO:0009894 113 0.015
cell cycle GO:0007049 101 0.015
ion homeostasis GO:0050801 212 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
spindle organization GO:0007051 2 0.015
cellular protein complex assembly GO:0043623 44 0.015
regulation of cell motility GO:2000145 131 0.015
synapse organization GO:0050808 46 0.015
positive regulation of nervous system development GO:0051962 178 0.015
negative regulation of molecular function GO:0044092 133 0.014
peptidyl amino acid modification GO:0018193 126 0.014
muscle cell differentiation GO:0042692 52 0.014
brain development GO:0007420 247 0.014
regulation of hydrolase activity GO:0051336 143 0.014
response to ketone GO:1901654 182 0.014
positive regulation of locomotion GO:0040017 102 0.014
dendrite morphogenesis GO:0048813 43 0.014
cytoplasmic transport GO:0016482 115 0.014
regulation of neuron death GO:1901214 115 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
single organism membrane organization GO:0044802 74 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
circulatory system development GO:0072359 134 0.014
organelle localization GO:0051640 55 0.014
gamete generation GO:0007276 124 0.014
response to calcium ion GO:0051592 59 0.014
response to oxidative stress GO:0006979 186 0.013
organophosphate metabolic process GO:0019637 370 0.013
regulation of hormone levels GO:0010817 187 0.013
response to glucocorticoid GO:0051384 223 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
cell cell signaling GO:0007267 335 0.013
organic substance catabolic process GO:1901575 316 0.013
dendrite development GO:0016358 72 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
synaptic transmission GO:0007268 235 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
immune system process GO:0002376 204 0.013
regulation of protein transport GO:0051223 68 0.013
development of primary sexual characteristics GO:0045137 107 0.013
nucleoside catabolic process GO:0009164 126 0.013
response to retinoic acid GO:0032526 63 0.013
behavior GO:0007610 205 0.013
regulation of actin cytoskeleton organization GO:0032956 30 0.013
circadian regulation of gene expression GO:0032922 3 0.013
positive regulation of cell communication GO:0010647 271 0.013
nucleotide metabolic process GO:0009117 279 0.013
cell adhesion GO:0007155 110 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
regulation of kinase activity GO:0043549 117 0.013
response to temperature stimulus GO:0009266 94 0.013
negative regulation of signal transduction GO:0009968 83 0.013
transmembrane transport GO:0055085 412 0.013
response to estrogen GO:0043627 232 0.013
response to alkaloid GO:0043279 132 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
positive regulation of secretion GO:0051047 140 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of neuron death GO:1901215 69 0.012
lipid storage GO:0019915 1 0.012
response to cytokine GO:0034097 215 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
ion transmembrane transport GO:0034220 365 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
neuron apoptotic process GO:0051402 88 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
oxidation reduction process GO:0055114 304 0.012
alcohol metabolic process GO:0006066 77 0.012
muscle system process GO:0003012 115 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of innate immune response GO:0045824 4 0.012
endomembrane system organization GO:0010256 48 0.012
gastrulation GO:0007369 2 0.012
regulation of membrane potential GO:0042391 110 0.012
response to camp GO:0051591 91 0.012
organ morphogenesis GO:0009887 75 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.012
regulation of protein serine threonine kinase activity GO:0071900 64 0.012
positive regulation of protein transport GO:0051222 41 0.012
tube formation GO:0035148 3 0.012
male gamete generation GO:0048232 99 0.012
embryonic pattern specification GO:0009880 1 0.012
eye morphogenesis GO:0048592 4 0.012
regulation of cellular component size GO:0032535 51 0.012
adult locomotory behavior GO:0008344 4 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
nitrogen compound transport GO:0071705 229 0.012
cellular response to abiotic stimulus GO:0071214 85 0.011
learning or memory GO:0007611 90 0.011
heart development GO:0007507 72 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
rho protein signal transduction GO:0007266 11 0.011
motor neuron axon guidance GO:0008045 1 0.011
small molecule biosynthetic process GO:0044283 124 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
lipid localization GO:0010876 62 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
positive regulation of immune system process GO:0002684 90 0.011
anion transport GO:0006820 178 0.011
response to insulin GO:0032868 133 0.011
maintenance of location GO:0051235 17 0.011
cell cycle checkpoint GO:0000075 2 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
protein homooligomerization GO:0051260 91 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of protein kinase activity GO:0045859 105 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
negative regulation of transport GO:0051051 136 0.011
female pregnancy GO:0007565 122 0.011
sensory organ development GO:0007423 74 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
positive regulation of transferase activity GO:0051347 81 0.011
peptide metabolic process GO:0006518 32 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
defense response GO:0006952 194 0.011
actin filament organization GO:0007015 42 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
axis specification GO:0009798 4 0.011
positive regulation of protein metabolic process GO:0051247 178 0.010
dephosphorylation GO:0016311 98 0.010
regulation of cellular component movement GO:0051270 150 0.010
regulation of immune system process GO:0002682 123 0.010
regulation of cytokine production GO:0001817 56 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
bmp signaling pathway GO:0030509 4 0.010
positive regulation of endothelial cell migration GO:0010595 4 0.010
chemotaxis GO:0006935 66 0.010
blood circulation GO:0008015 183 0.010
organophosphate catabolic process GO:0046434 148 0.010
somatic stem cell division GO:0048103 2 0.010
metal ion transport GO:0030001 289 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
cellular cation homeostasis GO:0030003 180 0.010
cytokine biosynthetic process GO:0042089 3 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
aminoglycan biosynthetic process GO:0006023 4 0.010
positive regulation of cell migration GO:0030335 96 0.010

Pi4kb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
nervous system disease DOID:863 0 0.063
musculoskeletal system disease DOID:17 0 0.032
connective tissue disease DOID:65 0 0.016
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.012
epilepsy syndrome DOID:1826 0 0.011
brain disease DOID:936 0 0.011