Rattus norvegicus

139 known processes

Spp1

secreted phosphoprotein 1

(Aliases: OSP)

Spp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient GO:0007584 248 0.337
response to wounding GO:0009611 254 0.308
cell motility GO:0048870 202 0.268
cation transport GO:0006812 382 0.210
regulation of cellular component movement GO:0051270 150 0.175
response to external biotic stimulus GO:0043207 221 0.172
response to extracellular stimulus GO:0009991 380 0.169
cellular response to endogenous stimulus GO:0071495 377 0.168
cellular component movement GO:0006928 248 0.163
cellular component assembly GO:0022607 360 0.163
vesicle mediated transport GO:0016192 181 0.154
regulation of cell motility GO:2000145 131 0.153
negative regulation of response to stimulus GO:0048585 155 0.151
regulation of locomotion GO:0040012 148 0.148
protein complex subunit organization GO:0071822 302 0.146
chemical homeostasis GO:0048878 292 0.144
programmed cell death GO:0012501 392 0.142
wound healing GO:0042060 122 0.142
regulation of programmed cell death GO:0043067 341 0.142
cell cell signaling GO:0007267 335 0.140
carboxylic acid biosynthetic process GO:0046394 83 0.135
locomotion GO:0040011 237 0.134
positive regulation of cell migration GO:0030335 96 0.131
cell migration GO:0016477 197 0.130
macromolecular complex subunit organization GO:0043933 339 0.127
anatomical structure morphogenesis GO:0009653 298 0.126
organic acid metabolic process GO:0006082 292 0.125
defense response GO:0006952 194 0.125
cellular lipid metabolic process GO:0044255 208 0.120
response to vitamin GO:0033273 131 0.119
response to estrogen GO:0043627 232 0.115
regulation of cellular component organization GO:0051128 368 0.114
cellular response to stress GO:0033554 269 0.112
transmembrane transport GO:0055085 412 0.111
neuron differentiation GO:0030182 368 0.109
protein complex assembly GO:0006461 263 0.107
cellular response to organic cyclic compound GO:0071407 202 0.106
positive regulation of cell motility GO:2000147 97 0.105
regulation of apoptotic process GO:0042981 335 0.104
cellular component biogenesis GO:0044085 368 0.101
response to other organism GO:0051707 220 0.101
response to mechanical stimulus GO:0009612 134 0.100
response to molecule of bacterial origin GO:0002237 194 0.100
metal ion transport GO:0030001 289 0.099
apoptotic process GO:0006915 381 0.097
tissue regeneration GO:0042246 36 0.096
lipid metabolic process GO:0006629 283 0.095
positive regulation of cell communication GO:0010647 271 0.095
tissue development GO:0009888 252 0.095
regulation of cell migration GO:0030334 128 0.091
localization of cell GO:0051674 202 0.089
aging GO:0007568 241 0.086
developmental growth GO:0048589 100 0.086
cellular response to oxygen containing compound GO:1901701 386 0.086
central nervous system development GO:0007417 311 0.084
response to bacterium GO:0009617 200 0.084
reproductive process GO:0022414 372 0.084
regulation of cell development GO:0060284 263 0.083
cell projection organization GO:0030030 302 0.082
positive regulation of transport GO:0051050 245 0.082
ion transmembrane transport GO:0034220 365 0.082
positive regulation of multicellular organismal process GO:0051240 387 0.081
response to nutrient levels GO:0031667 370 0.079
cellular response to nitrogen compound GO:1901699 210 0.078
regulation of nervous system development GO:0051960 264 0.077
protein complex biogenesis GO:0070271 263 0.076
cellular cation homeostasis GO:0030003 180 0.076
response to ethanol GO:0045471 162 0.076
regulation of ion transport GO:0043269 245 0.076
response to inorganic substance GO:0010035 377 0.076
regulation of metal ion transport GO:0010959 118 0.075
cellular metal ion homeostasis GO:0006875 172 0.074
growth GO:0040007 165 0.074
positive regulation of response to stimulus GO:0048584 285 0.073
response to metal ion GO:0010038 253 0.073
regulation of molecular function GO:0065009 398 0.072
negative regulation of cellular biosynthetic process GO:0031327 161 0.071
regulation of response to external stimulus GO:0032101 106 0.071
response to corticosteroid GO:0031960 235 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.069
response to growth factor GO:0070848 189 0.067
response to glucocorticoid GO:0051384 223 0.066
oxoacid metabolic process GO:0043436 290 0.066
carboxylic acid metabolic process GO:0019752 289 0.065
positive regulation of ion transport GO:0043270 94 0.064
response to lipopolysaccharide GO:0032496 191 0.064
response to tumor necrosis factor GO:0034612 56 0.063
multicellular organismal reproductive process GO:0048609 233 0.062
single organism biosynthetic process GO:0044711 342 0.061
cellular ion homeostasis GO:0006873 184 0.061
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.060
cellular response to lipid GO:0071396 201 0.060
macromolecular complex assembly GO:0065003 273 0.059
cellular homeostasis GO:0019725 252 0.058
homeostatic process GO:0042592 331 0.058
single organism catabolic process GO:0044712 283 0.058
regulation of cell proliferation GO:0042127 359 0.057
single organism organelle organization GO:1902589 180 0.057
negative regulation of cell death GO:0060548 229 0.057
multicellular organism reproduction GO:0032504 233 0.057
regulation of neurogenesis GO:0050767 247 0.056
response to axon injury GO:0048678 59 0.056
calcium ion transport GO:0006816 131 0.056
positive regulation of cellular component organization GO:0051130 200 0.056
developmental process involved in reproduction GO:0003006 159 0.055
positive regulation of nervous system development GO:0051962 178 0.054
regulation of cellular localization GO:0060341 263 0.054
fatty acid metabolic process GO:0006631 99 0.054
regulation of phosphate metabolic process GO:0019220 349 0.053
protein oligomerization GO:0051259 191 0.053
neuron projection development GO:0031175 273 0.051
single organism reproductive process GO:0044702 297 0.050
cellular component morphogenesis GO:0032989 155 0.050
behavior GO:0007610 205 0.050
gastrulation GO:0007369 2 0.050
small molecule biosynthetic process GO:0044283 124 0.049
organic acid biosynthetic process GO:0016053 83 0.049
response to oxidative stress GO:0006979 186 0.049
intracellular signal transduction GO:0035556 314 0.049
organelle organization GO:0006996 266 0.049
inflammatory response GO:0006954 150 0.048
negative regulation of metabolic process GO:0009892 331 0.047
anion transport GO:0006820 178 0.047
single organism intracellular transport GO:1902582 166 0.046
cellular response to growth factor stimulus GO:0071363 162 0.046
positive regulation of cell development GO:0010720 176 0.045
cellular response to tumor necrosis factor GO:0071356 46 0.044
response to peptide GO:1901652 292 0.043
regulation of cell differentiation GO:0045595 320 0.043
regeneration GO:0031099 163 0.043
synaptic transmission GO:0007268 235 0.043
positive regulation of locomotion GO:0040017 102 0.042
secretion by cell GO:0032940 248 0.042
reproduction GO:0000003 245 0.042
positive regulation of signaling GO:0023056 270 0.042
calcium ion homeostasis GO:0055074 162 0.042
monocarboxylic acid metabolic process GO:0032787 152 0.042
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.042
neuron development GO:0048666 286 0.041
lipid biosynthetic process GO:0008610 128 0.040
regulation of neuron differentiation GO:0045664 208 0.040
cell part morphogenesis GO:0032990 123 0.039
positive regulation of programmed cell death GO:0043068 157 0.039
response to biotic stimulus GO:0009607 226 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.038
response to estradiol GO:0032355 164 0.038
endocytosis GO:0006897 84 0.038
divalent inorganic cation homeostasis GO:0072507 165 0.038
cellular response to hormone stimulus GO:0032870 247 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.038
positive regulation of cell proliferation GO:0008284 249 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.037
proteolysis GO:0006508 175 0.037
cellular response to corticosteroid stimulus GO:0071384 69 0.037
cellular response to extracellular stimulus GO:0031668 73 0.037
positive regulation of apoptotic process GO:0043065 154 0.037
neuron death GO:0070997 127 0.036
positive regulation of neurogenesis GO:0050769 165 0.036
nucleic acid templated transcription GO:0097659 379 0.036
regulation of blood circulation GO:1903522 110 0.035
rna biosynthetic process GO:0032774 380 0.035
response to purine containing compound GO:0014074 126 0.035
regulation of rna metabolic process GO:0051252 391 0.034
catabolic process GO:0009056 351 0.034
regulation of system process GO:0044057 208 0.034
positive regulation of calcium ion transport GO:0051928 36 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
hormone secretion GO:0046879 115 0.034
actin filament based process GO:0030029 86 0.034
rna metabolic process GO:0016070 406 0.034
neuron projection morphogenesis GO:0048812 122 0.033
secretion GO:0046903 307 0.033
nitrogen compound transport GO:0071705 229 0.033
regulation of signal transduction GO:0009966 318 0.033
response to transition metal nanoparticle GO:1990267 122 0.033
response to organophosphorus GO:0046683 102 0.033
regulation of protein metabolic process GO:0051246 289 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.032
transcription dna templated GO:0006351 377 0.032
regulation of vesicle mediated transport GO:0060627 81 0.032
positive regulation of gene expression GO:0010628 244 0.032
epithelium development GO:0060429 96 0.032
response to peptide hormone GO:0043434 278 0.032
regulation of hormone levels GO:0010817 187 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
reproductive system development GO:0061458 128 0.032
signal release GO:0023061 145 0.031
response to reactive oxygen species GO:0000302 120 0.031
response to antidepressant GO:0036276 4 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
blood circulation GO:0008015 183 0.031
cytosolic calcium ion homeostasis GO:0051480 140 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
regulation of response to wounding GO:1903034 69 0.031
neurological system process GO:0050877 219 0.030
cellular amine metabolic process GO:0044106 38 0.030
alcohol metabolic process GO:0006066 77 0.030
positive regulation of neuron differentiation GO:0045666 126 0.030
positive regulation of cell projection organization GO:0031346 111 0.030
positive regulation of synaptic transmission GO:0050806 62 0.030
regulation of defense response GO:0031347 68 0.029
positive regulation of molecular function GO:0044093 230 0.029
rhythmic process GO:0048511 156 0.029
regulation of cellular extravasation GO:0002691 2 0.029
divalent inorganic cation transport GO:0072511 134 0.028
protein phosphorylation GO:0006468 345 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
maternal process involved in female pregnancy GO:0060135 38 0.028
cellular response to external stimulus GO:0071496 118 0.027
regulation of synaptic transmission GO:0050804 141 0.027
cellular chemical homeostasis GO:0055082 247 0.027
multi organism reproductive process GO:0044703 262 0.027
organonitrogen compound biosynthetic process GO:1901566 167 0.027
multi multicellular organism process GO:0044706 138 0.027
regulation of calcium ion transport GO:0051924 77 0.027
axonogenesis GO:0007409 71 0.027
regulation of phosphorylation GO:0042325 248 0.026
cellular response to glucocorticoid stimulus GO:0071385 68 0.026
response to ketone GO:1901654 182 0.026
regulation of catalytic activity GO:0050790 304 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
purine containing compound metabolic process GO:0072521 253 0.026
regulation of response to stress GO:0080134 126 0.026
macromolecule localization GO:0033036 252 0.026
cell chemotaxis GO:0060326 31 0.026
cellular response to steroid hormone stimulus GO:0071383 93 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
positive regulation of phosphorylation GO:0042327 177 0.025
muscle system process GO:0003012 115 0.025
cellular response to ketone GO:1901655 51 0.025
negative regulation of innate immune response GO:0045824 4 0.025
regulation of neuron death GO:1901214 115 0.025
response to cytokine GO:0034097 215 0.025
organic substance catabolic process GO:1901575 316 0.025
response to oxygen levels GO:0070482 265 0.025
macrophage chemotaxis GO:0048246 2 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
positive regulation of neuron projection development GO:0010976 99 0.025
immune system process GO:0002376 204 0.024
regulation of transmembrane transport GO:0034762 122 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
cellular response to oxidative stress GO:0034599 76 0.024
organophosphate metabolic process GO:0019637 370 0.024
intracellular transport GO:0046907 185 0.024
biological adhesion GO:0022610 110 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
female pregnancy GO:0007565 122 0.024
response to carbohydrate GO:0009743 183 0.023
cellular ketone metabolic process GO:0042180 51 0.023
cellular calcium ion homeostasis GO:0006874 160 0.023
protein homooligomerization GO:0051260 91 0.023
positive regulation of signal transduction GO:0009967 175 0.023
response to hydrogen peroxide GO:0042542 89 0.023
regulation of transcription dna templated GO:0006355 374 0.023
positive regulation of response to external stimulus GO:0032103 51 0.023
positive regulation of cell death GO:0010942 184 0.023
divalent metal ion transport GO:0070838 132 0.022
response to zinc ion GO:0010043 39 0.022
negative regulation of cell communication GO:0010648 158 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
response to hexose GO:0009746 144 0.022
cellular response to molecule of bacterial origin GO:0071219 56 0.022
leukocyte chemotaxis GO:0030595 22 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
regulation of immune system process GO:0002682 123 0.022
response to camp GO:0051591 91 0.022
response to glucose GO:0009749 136 0.022
cytoplasmic transport GO:0016482 115 0.022
positive regulation of developmental process GO:0051094 283 0.021
metal ion homeostasis GO:0055065 186 0.021
limb morphogenesis GO:0035108 4 0.021
regulation of secretion by cell GO:1903530 208 0.021
ras protein signal transduction GO:0007265 29 0.021
response to toxic substance GO:0009636 133 0.021
regulation of ion transmembrane transport GO:0034765 121 0.021
gliogenesis GO:0042063 93 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
regulation of cell projection organization GO:0031344 175 0.020
response to radiation GO:0009314 137 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
amide transport GO:0042886 105 0.020
positive regulation of secretion GO:0051047 140 0.020
negative regulation of signaling GO:0023057 157 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
positive regulation of voltage gated calcium channel activity GO:1901387 1 0.020
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
regulation of cell adhesion GO:0030155 52 0.019
regulation of cellular component biogenesis GO:0044087 86 0.019
response to vitamin d GO:0033280 34 0.019
brain development GO:0007420 247 0.019
ion homeostasis GO:0050801 212 0.019
epithelial cell proliferation GO:0050673 54 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
regulation of neuron projection development GO:0010975 161 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
epithelial cell differentiation GO:0030855 71 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
regulation of homeostatic process GO:0032844 101 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
reproductive structure development GO:0048608 128 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
innate immune response GO:0045087 35 0.018
cellular catabolic process GO:0044248 295 0.018
cellular response to peptide GO:1901653 133 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
protein maturation GO:0051604 68 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
cellular response to alcohol GO:0097306 87 0.018
negative regulation of gene expression GO:0010629 199 0.018
circulatory system process GO:0003013 183 0.018
regulation of skeletal muscle cell differentiation GO:2001014 1 0.018
ribose phosphate metabolic process GO:0019693 235 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
cell adhesion GO:0007155 110 0.017
regulation of camp metabolic process GO:0030814 43 0.017
protein transport GO:0015031 132 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
dna metabolic process GO:0006259 96 0.017
regulation of inflammatory response GO:0050727 48 0.017
head development GO:0060322 247 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
cell type specific apoptotic process GO:0097285 134 0.017
negative regulation of developmental process GO:0051093 125 0.017
negative regulation of neuron differentiation GO:0045665 62 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
regulation of membrane potential GO:0042391 110 0.017
response to high density lipoprotein particle GO:0055099 2 0.017
sexual reproduction GO:0019953 148 0.017
skeletal muscle tissue regeneration GO:0043403 10 0.017
regulation of anatomical structure size GO:0090066 135 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
cellular response to nutrient levels GO:0031669 60 0.017
positive regulation of secretion by cell GO:1903532 128 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.016
lipid transport GO:0006869 61 0.016
regulation of hydrolase activity GO:0051336 143 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
cation homeostasis GO:0055080 195 0.016
regulation of blood pressure GO:0008217 83 0.016
regulation of cytokine production GO:0001817 56 0.016
unsaturated fatty acid biosynthetic process GO:0006636 21 0.016
regulation of lymphocyte migration GO:2000401 1 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
actin cytoskeleton organization GO:0030036 73 0.016
cell morphogenesis GO:0000902 142 0.016
regulation of endocytosis GO:0030100 42 0.016
receptor mediated endocytosis GO:0006898 42 0.016
hormone transport GO:0009914 121 0.016
protein heterooligomerization GO:0051291 89 0.015
positive regulation of hormone secretion GO:0046887 65 0.015
organic anion transport GO:0015711 132 0.015
axon development GO:0061564 96 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
response to monosaccharide GO:0034284 159 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
regulation of catabolic process GO:0009894 113 0.015
interleukin 1 production GO:0032612 11 0.015
phospholipid metabolic process GO:0006644 61 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
amine metabolic process GO:0009308 38 0.015
acute inflammatory response GO:0002526 58 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
eosinophil chemotaxis GO:0048245 3 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
glycerolipid metabolic process GO:0046486 67 0.015
positive regulation of cellular component biogenesis GO:0044089 55 0.015
regulation of ion homeostasis GO:2000021 63 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
negative regulation of protein metabolic process GO:0051248 114 0.014
protein localization GO:0008104 191 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
negative regulation of neuron apoptotic process GO:0043524 45 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
regulation of reactive oxygen species metabolic process GO:2000377 26 0.014
cellular response to interleukin 1 GO:0071347 37 0.014
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
defense response to gram negative bacterium GO:0050829 3 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
peptidyl amino acid modification GO:0018193 126 0.014
muscle structure development GO:0061061 87 0.014
dephosphorylation GO:0016311 98 0.014
regulation of cell activation GO:0050865 50 0.014
response to indole 3 methanol GO:0071680 2 0.014
action potential GO:0001508 54 0.014
positive regulation of lymphocyte migration GO:2000403 1 0.014
response to fibroblast growth factor GO:0071774 29 0.014
negative regulation of transport GO:0051051 136 0.014
muscle contraction GO:0006936 88 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
sequestering of calcium ion GO:0051208 8 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
negative regulation of neuron death GO:1901215 69 0.014
lymphocyte migration GO:0072676 3 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
regulation of t cell migration GO:2000404 1 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
cellular response to reactive oxygen species GO:0034614 55 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
nucleotide metabolic process GO:0009117 279 0.013
response to fatty acid GO:0070542 65 0.013
smooth muscle cell migration GO:0014909 36 0.013
mononuclear cell migration GO:0071674 3 0.013
regulation of secretion GO:0051046 224 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
icosanoid metabolic process GO:0006690 38 0.013
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.013
response to electrical stimulus GO:0051602 56 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
formation of primary germ layer GO:0001704 1 0.013
positive regulation of protein modification process GO:0031401 142 0.013
negative regulation of molecular function GO:0044092 133 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
striated muscle tissue development GO:0014706 58 0.012
sensory perception GO:0007600 101 0.012
response to amino acid GO:0043200 75 0.012
response to activity GO:0014823 73 0.012
response to alkaloid GO:0043279 132 0.012
immune response GO:0006955 104 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
actin filament organization GO:0007015 42 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
multicellular organismal signaling GO:0035637 44 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
apoptotic signaling pathway GO:0097190 27 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
glial cell differentiation GO:0010001 65 0.012
gamete generation GO:0007276 124 0.012
cell projection morphogenesis GO:0048858 123 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
regulation of peptidase activity GO:0052547 55 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
positive regulation of behavior GO:0048520 38 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
endomembrane system organization GO:0010256 48 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
transmission of nerve impulse GO:0019226 42 0.012
regulation of protein modification process GO:0031399 194 0.012
positive regulation of homeostatic process GO:0032846 49 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
membrane organization GO:0061024 94 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
chemotaxis GO:0006935 66 0.011
cellular response to acid chemical GO:0071229 75 0.011
insulin secretion GO:0030073 69 0.011
sex differentiation GO:0007548 113 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
carbohydrate homeostasis GO:0033500 75 0.011
anion transmembrane transport GO:0098656 77 0.011
cellular response to drug GO:0035690 30 0.011
protein processing GO:0016485 68 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of body fluid levels GO:0050878 90 0.011
leukocyte activation GO:0045321 76 0.011
regulation of blood vessel size GO:0050880 89 0.011
skeletal muscle cell differentiation GO:0035914 2 0.011
astrocyte differentiation GO:0048708 19 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
axis specification GO:0009798 4 0.011
actin filament bundle assembly GO:0051017 19 0.011
positive regulation of defense response GO:0031349 37 0.011
response to vitamin k GO:0032571 4 0.011
negative regulation of response to tumor cell GO:0002835 2 0.011
sequestering of metal ion GO:0051238 9 0.011
cellular macromolecule localization GO:0070727 122 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
neuronal action potential GO:0019228 35 0.011
response to ionizing radiation GO:0010212 59 0.011
response to dexamethasone GO:0071548 49 0.011
negative regulation of homeostatic process GO:0032845 47 0.011
response to transforming growth factor beta GO:0071559 46 0.011
positive regulation of cytokine production GO:0001819 42 0.011
cellular response to metal ion GO:0071248 55 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011

Spp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.015
sensory system disease DOID:0050155 0 0.012