Rattus norvegicus

0 known processes

Srxn1

sulfiredoxin 1 homolog (S. cerevisiae)

(Aliases: Ab2-390,Npn3)

Srxn1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to oxidative stress GO:0006979 186 0.142
regulation of nucleic acid templated transcription GO:1903506 380 0.122
response to hydrogen peroxide GO:0042542 89 0.113
immune response GO:0006955 104 0.108
regulation of transcription dna templated GO:0006355 374 0.093
response to inorganic substance GO:0010035 377 0.091
regulation of cell proliferation GO:0042127 359 0.090
cofactor metabolic process GO:0051186 95 0.087
cellular response to oxygen containing compound GO:1901701 386 0.086
tetrapyrrole metabolic process GO:0033013 11 0.083
regulation of rna metabolic process GO:0051252 391 0.076
small molecule biosynthetic process GO:0044283 124 0.075
transcription dna templated GO:0006351 377 0.074
rna biosynthetic process GO:0032774 380 0.073
negative regulation of cell death GO:0060548 229 0.072
cellular response to oxidative stress GO:0034599 76 0.072
neuron death GO:0070997 127 0.069
oxoacid metabolic process GO:0043436 290 0.067
carboxylic acid metabolic process GO:0019752 289 0.063
response to estrogen GO:0043627 232 0.062
single organism reproductive process GO:0044702 297 0.061
regulation of rna biosynthetic process GO:2001141 381 0.060
intracellular signal transduction GO:0035556 314 0.060
response to extracellular stimulus GO:0009991 380 0.058
apoptotic process GO:0006915 381 0.058
cell type specific apoptotic process GO:0097285 134 0.057
response to nutrient levels GO:0031667 370 0.057
positive regulation of developmental process GO:0051094 283 0.057
transcription from rna polymerase ii promoter GO:0006366 252 0.056
nucleic acid templated transcription GO:0097659 379 0.056
cellular response to stress GO:0033554 269 0.056
cellular amino acid metabolic process GO:0006520 107 0.054
reactive oxygen species metabolic process GO:0072593 37 0.050
response to nutrient GO:0007584 248 0.050
programmed cell death GO:0012501 392 0.049
regulation of neuron apoptotic process GO:0043523 83 0.049
tissue development GO:0009888 252 0.049
response to peptide GO:1901652 292 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.048
cellular response to reactive oxygen species GO:0034614 55 0.047
positive regulation of multicellular organismal process GO:0051240 387 0.045
anatomical structure morphogenesis GO:0009653 298 0.045
mesoderm development GO:0007498 2 0.045
reproductive process GO:0022414 372 0.044
organic acid metabolic process GO:0006082 292 0.043
response to oxygen levels GO:0070482 265 0.043
cellular ketone metabolic process GO:0042180 51 0.042
oxidation reduction process GO:0055114 304 0.042
negative regulation of apoptotic process GO:0043066 181 0.041
regulation of neuron death GO:1901214 115 0.041
glutathione metabolic process GO:0006749 15 0.040
cellular amino acid biosynthetic process GO:0008652 32 0.040
response to reactive oxygen species GO:0000302 120 0.040
circulatory system process GO:0003013 183 0.040
blood circulation GO:0008015 183 0.040
sulfur compound metabolic process GO:0006790 70 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
response to metal ion GO:0010038 253 0.037
secretion GO:0046903 307 0.037
alpha amino acid metabolic process GO:1901605 71 0.037
cellular catabolic process GO:0044248 295 0.037
negative regulation of neuron death GO:1901215 69 0.036
porphyrin containing compound metabolic process GO:0006778 8 0.035
positive regulation of rna biosynthetic process GO:1902680 197 0.035
negative regulation of mast cell activation GO:0033004 3 0.035
single organism catabolic process GO:0044712 283 0.035
leukocyte activation involved in immune response GO:0002366 16 0.034
positive regulation of biosynthetic process GO:0009891 319 0.033
positive regulation of immune system process GO:0002684 90 0.033
immune effector process GO:0002252 53 0.032
regulation of apoptotic process GO:0042981 335 0.032
response to decreased oxygen levels GO:0036293 237 0.031
immune system process GO:0002376 204 0.030
single organism carbohydrate metabolic process GO:0044723 118 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
myeloid leukocyte activation GO:0002274 36 0.029
gastrulation GO:0007369 2 0.029
protein complex assembly GO:0006461 263 0.029
negative regulation of multicellular organismal process GO:0051241 203 0.029
single organism biosynthetic process GO:0044711 342 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
protein oligomerization GO:0051259 191 0.027
glutathione biosynthetic process GO:0006750 3 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
response to radiation GO:0009314 137 0.026
negative regulation of molecular function GO:0044092 133 0.026
carboxylic acid biosynthetic process GO:0046394 83 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
protein complex biogenesis GO:0070271 263 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
mast cell cytokine production GO:0032762 1 0.026
response to wounding GO:0009611 254 0.025
neuron differentiation GO:0030182 368 0.025
exocytosis GO:0006887 60 0.024
positive regulation of cell death GO:0010942 184 0.024
formation of primary germ layer GO:0001704 1 0.024
regulation of cellular localization GO:0060341 263 0.024
negative regulation of secretion GO:0051048 82 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
response to other organism GO:0051707 220 0.023
single organism intracellular transport GO:1902582 166 0.023
regulation of cytokine production GO:0001817 56 0.023
regulation of cell differentiation GO:0045595 320 0.023
amine metabolic process GO:0009308 38 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.023
rna metabolic process GO:0016070 406 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
cellular amide metabolic process GO:0043603 44 0.022
organic acid biosynthetic process GO:0016053 83 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
regulation of response to stress GO:0080134 126 0.022
cellular response to extracellular stimulus GO:0031668 73 0.022
cellular modified amino acid metabolic process GO:0006575 61 0.021
multicellular organism growth GO:0035264 1 0.021
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
response to estradiol GO:0032355 164 0.021
secretion by cell GO:0032940 248 0.021
cation transport GO:0006812 382 0.021
myeloid cell activation involved in immune response GO:0002275 13 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
organic anion transport GO:0015711 132 0.021
negative regulation of secretion by cell GO:1903531 72 0.021
cellular modified amino acid biosynthetic process GO:0042398 18 0.021
negative regulation of transcription dna templated GO:0045892 116 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
regulation of secretion GO:0051046 224 0.020
negative regulation of transport GO:0051051 136 0.020
regulation of immune response GO:0050776 55 0.020
response to hypoxia GO:0001666 231 0.020
regulation of blood pressure GO:0008217 83 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
regulation of immune effector process GO:0002697 32 0.020
regulation of programmed cell death GO:0043067 341 0.019
cellular response to peptide GO:1901653 133 0.019
negative regulation of neuron apoptotic process GO:0043524 45 0.019
regulation of leukocyte activation GO:0002694 45 0.019
blood vessel development GO:0001568 69 0.019
intracellular transport GO:0046907 185 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
regulation of immune system process GO:0002682 123 0.019
regulation of secretion by cell GO:1903530 208 0.019
protein complex subunit organization GO:0071822 302 0.019
peptidyl amino acid modification GO:0018193 126 0.019
cellular response to endogenous stimulus GO:0071495 377 0.018
pyridine containing compound metabolic process GO:0072524 32 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
response to peptide hormone GO:0043434 278 0.018
organic acid transport GO:0015849 116 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
muscle cell proliferation GO:0033002 84 0.018
peptide biosynthetic process GO:0043043 3 0.018
response to growth factor GO:0070848 189 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
multicellular organism reproduction GO:0032504 233 0.018
proteolysis GO:0006508 175 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cellular component assembly GO:0022607 360 0.017
nicotinamide nucleotide metabolic process GO:0046496 28 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
regulation of immunoglobulin production GO:0002637 4 0.017
positive regulation of cell communication GO:0010647 271 0.016
reproductive structure development GO:0048608 128 0.016
aging GO:0007568 241 0.016
macromolecular complex assembly GO:0065003 273 0.016
regulation of hormone levels GO:0010817 187 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
cellular amine metabolic process GO:0044106 38 0.016
response to interleukin 1 GO:0070555 55 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
leukocyte activation GO:0045321 76 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
positive regulation of immunoglobulin production GO:0002639 4 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
tube development GO:0035295 89 0.016
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.016
epithelium development GO:0060429 96 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
catabolic process GO:0009056 351 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
negative regulation of metabolic process GO:0009892 331 0.015
central nervous system development GO:0007417 311 0.015
response to increased oxygen levels GO:0036296 45 0.015
chemical homeostasis GO:0048878 292 0.015
circulatory system development GO:0072359 134 0.015
cell activation involved in immune response GO:0002263 16 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
multi organism reproductive process GO:0044703 262 0.015
regulation of cell development GO:0060284 263 0.015
regulation of ion transport GO:0043269 245 0.014
leukocyte mediated immunity GO:0002443 28 0.014
carbohydrate metabolic process GO:0005975 130 0.014
regulation of angiogenesis GO:0045765 39 0.014
positive regulation of gene expression GO:0010628 244 0.014
carboxylic acid transport GO:0046942 115 0.014
cytokine production GO:0001816 61 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.014
cellular response to external stimulus GO:0071496 118 0.014
regulation of defense response GO:0031347 68 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulated secretory pathway GO:0045055 17 0.014
cardiovascular system development GO:0072358 134 0.014
organic substance catabolic process GO:1901575 316 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
cellular cation homeostasis GO:0030003 180 0.014
reproduction GO:0000003 245 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
response to glucocorticoid GO:0051384 223 0.013
transmembrane transport GO:0055085 412 0.013
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.013
nucleotide metabolic process GO:0009117 279 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
regulation of cell motility GO:2000145 131 0.013
defense response GO:0006952 194 0.013
alcohol biosynthetic process GO:0046165 38 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
cation transmembrane transport GO:0098655 263 0.013
cellular response to hydrogen peroxide GO:0070301 42 0.012
positive regulation of immune response GO:0050778 42 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
regulation of neuron differentiation GO:0045664 208 0.012
anion transport GO:0006820 178 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
reproductive system development GO:0061458 128 0.012
regulation of molecular function GO:0065009 398 0.012
response to external biotic stimulus GO:0043207 221 0.012
monocarboxylic acid transport GO:0015718 52 0.012
neuron development GO:0048666 286 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
ion homeostasis GO:0050801 212 0.012
cellular macromolecule localization GO:0070727 122 0.012
pyridine nucleotide metabolic process GO:0019362 28 0.012
anterior posterior pattern specification GO:0009952 1 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
selenium compound metabolic process GO:0001887 2 0.012
single organism cellular localization GO:1902580 102 0.012
lipid biosynthetic process GO:0008610 128 0.012
cell activation GO:0001775 97 0.012
regulation of mast cell activation involved in immune response GO:0033006 6 0.012
pigment metabolic process GO:0042440 7 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
regulation of metanephros development GO:0072215 4 0.012
cell cell signaling GO:0007267 335 0.012
mesoderm morphogenesis GO:0048332 1 0.012
mesenchymal cell proliferation GO:0010463 4 0.012
serine family amino acid metabolic process GO:0009069 12 0.011
positive regulation of signaling GO:0023056 270 0.011
response to ethanol GO:0045471 162 0.011
dna metabolic process GO:0006259 96 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
apoptotic signaling pathway GO:0097190 27 0.011
response to axon injury GO:0048678 59 0.011
positive regulation of immune effector process GO:0002699 19 0.011
regulation of vasculature development GO:1901342 44 0.011
response to ionizing radiation GO:0010212 59 0.011
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.011
mast cell activation GO:0045576 15 0.011
nonribosomal peptide biosynthetic process GO:0019184 3 0.011
response to ketone GO:1901654 182 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
growth GO:0040007 165 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
angiogenesis GO:0001525 53 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
metal ion transport GO:0030001 289 0.011
amino acid betaine metabolic process GO:0006577 3 0.011
hydrogen peroxide metabolic process GO:0042743 13 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
response to glucose GO:0009749 136 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
gamete generation GO:0007276 124 0.011
cation homeostasis GO:0055080 195 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
positive regulation of apoptotic process GO:0043065 154 0.010
kidney mesenchyme development GO:0072074 2 0.010
negative regulation of muscle cell apoptotic process GO:0010656 21 0.010
head development GO:0060322 247 0.010
nitrogen compound transport GO:0071705 229 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
regulation of membrane potential GO:0042391 110 0.010
cellular response to alcohol GO:0097306 87 0.010
cellular homeostasis GO:0019725 252 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
regulation of protein metabolic process GO:0051246 289 0.010
dephosphorylation GO:0016311 98 0.010
regulation of neurogenesis GO:0050767 247 0.010
cellular response to nutrient levels GO:0031669 60 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010

Srxn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.011
disease of metabolism DOID:0014667 0 0.011