Rattus norvegicus

7 known processes

Mep1b

meprin 1 beta

Mep1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of ion transport GO:0043269 245 0.532
transmembrane transport GO:0055085 412 0.470
chemical homeostasis GO:0048878 292 0.351
acid secretion GO:0046717 48 0.350
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.308
positive regulation of transport GO:0051050 245 0.304
positive regulation of multicellular organismal process GO:0051240 387 0.240
cation transmembrane transport GO:0098655 263 0.169
response to lipopolysaccharide GO:0032496 191 0.166
ion homeostasis GO:0050801 212 0.150
nitrogen compound transport GO:0071705 229 0.139
cellular metal ion homeostasis GO:0006875 172 0.134
cation transport GO:0006812 382 0.122
regulation of system process GO:0044057 208 0.121
cellular divalent inorganic cation homeostasis GO:0072503 162 0.115
divalent inorganic cation homeostasis GO:0072507 165 0.115
cellular chemical homeostasis GO:0055082 247 0.114
central nervous system development GO:0007417 311 0.110
organic acid metabolic process GO:0006082 292 0.109
ion transmembrane transport GO:0034220 365 0.109
cellular homeostasis GO:0019725 252 0.101
cellular ion homeostasis GO:0006873 184 0.098
organophosphate metabolic process GO:0019637 370 0.097
regulation of secretion by cell GO:1903530 208 0.091
cellular lipid metabolic process GO:0044255 208 0.090
regulation of hormone levels GO:0010817 187 0.088
response to peptide GO:1901652 292 0.088
muscle contraction GO:0006936 88 0.085
response to estradiol GO:0032355 164 0.083
cytosolic calcium ion homeostasis GO:0051480 140 0.083
behavior GO:0007610 205 0.082
positive regulation of secretion GO:0051047 140 0.082
response to oxidative stress GO:0006979 186 0.080
muscle system process GO:0003012 115 0.079
divalent metal ion transport GO:0070838 132 0.078
glycerolipid metabolic process GO:0046486 67 0.077
organophosphate catabolic process GO:0046434 148 0.075
inorganic ion transmembrane transport GO:0098660 229 0.073
regulation of molecular function GO:0065009 398 0.073
homeostatic process GO:0042592 331 0.073
positive regulation of ion transport GO:0043270 94 0.072
cation homeostasis GO:0055080 195 0.072
regulation of cell proliferation GO:0042127 359 0.069
carboxylic acid metabolic process GO:0019752 289 0.068
regulation of secretion GO:0051046 224 0.068
secretion GO:0046903 307 0.067
metal ion transport GO:0030001 289 0.067
choline transport GO:0015871 4 0.065
positive regulation of neurogenesis GO:0050769 165 0.063
cellular response to oxygen containing compound GO:1901701 386 0.061
lipid metabolic process GO:0006629 283 0.059
alcohol metabolic process GO:0006066 77 0.059
metal ion homeostasis GO:0055065 186 0.058
reproductive process GO:0022414 372 0.057
cell cell signaling GO:0007267 335 0.057
regulation of cellular localization GO:0060341 263 0.056
oxoacid metabolic process GO:0043436 290 0.055
nucleotide metabolic process GO:0009117 279 0.054
regulation of metal ion transport GO:0010959 118 0.053
oligopeptide transport GO:0006857 4 0.052
positive regulation of signaling GO:0023056 270 0.052
response to corticosteroid GO:0031960 235 0.051
g protein coupled receptor signaling pathway GO:0007186 242 0.050
positive regulation of cell proliferation GO:0008284 249 0.048
cellular response to lipid GO:0071396 201 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
positive regulation of cell differentiation GO:0045597 217 0.047
intracellular signal transduction GO:0035556 314 0.046
regulation of rna biosynthetic process GO:2001141 381 0.046
purine ribonucleotide catabolic process GO:0009154 136 0.046
calcium ion transport GO:0006816 131 0.046
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.045
response to molecule of bacterial origin GO:0002237 194 0.045
regulation of homeostatic process GO:0032844 101 0.044
purine containing compound metabolic process GO:0072521 253 0.044
response to biotic stimulus GO:0009607 226 0.043
organic hydroxy compound metabolic process GO:1901615 115 0.043
regulation of cell differentiation GO:0045595 320 0.043
blood circulation GO:0008015 183 0.042
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
regulation of ion transmembrane transport GO:0034765 121 0.041
regulation of transporter activity GO:0032409 50 0.041
cellular calcium ion homeostasis GO:0006874 160 0.041
carboxylic acid transport GO:0046942 115 0.041
cellular response to acid chemical GO:0071229 75 0.041
amino acid transport GO:0006865 70 0.041
phospholipid metabolic process GO:0006644 61 0.040
nucleoside monophosphate metabolic process GO:0009123 93 0.040
rna biosynthetic process GO:0032774 380 0.040
anion transport GO:0006820 178 0.040
divalent inorganic cation transport GO:0072511 134 0.040
sensory perception GO:0007600 101 0.039
positive regulation of protein phosphorylation GO:0001934 135 0.039
purine nucleotide metabolic process GO:0006163 229 0.039
regulation of peptide hormone secretion GO:0090276 80 0.039
response to acid chemical GO:0001101 222 0.038
positive regulation of calcium ion transport GO:0051928 36 0.038
positive regulation of cell communication GO:0010647 271 0.038
cellular ketone metabolic process GO:0042180 51 0.038
response to growth factor GO:0070848 189 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.038
positive regulation of protein metabolic process GO:0051247 178 0.037
calcium ion homeostasis GO:0055074 162 0.037
inorganic cation transmembrane transport GO:0098662 202 0.037
signal release GO:0023061 145 0.037
purine containing compound biosynthetic process GO:0072522 85 0.037
regulation of hormone secretion GO:0046883 106 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
positive regulation of hormone secretion GO:0046887 65 0.035
cellular amine metabolic process GO:0044106 38 0.035
organic cyclic compound catabolic process GO:1901361 175 0.034
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.034
response to peptide hormone GO:0043434 278 0.034
regulation of neurological system process GO:0031644 43 0.033
ribose phosphate metabolic process GO:0019693 235 0.032
nucleic acid templated transcription GO:0097659 379 0.032
single organism biosynthetic process GO:0044711 342 0.031
multi organism reproductive process GO:0044703 262 0.031
regulation of rna metabolic process GO:0051252 391 0.031
peptide transport GO:0015833 97 0.031
single organism intracellular transport GO:1902582 166 0.030
positive regulation of nervous system development GO:0051962 178 0.030
secretion by cell GO:0032940 248 0.030
neurological system process GO:0050877 219 0.029
anion transmembrane transport GO:0098656 77 0.029
cellular response to alcohol GO:0097306 87 0.029
grooming behavior GO:0007625 4 0.029
response to inorganic substance GO:0010035 377 0.028
response to bacterium GO:0009617 200 0.028
terpenoid metabolic process GO:0006721 37 0.028
regulation of transmembrane transport GO:0034762 122 0.028
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
cellular cation homeostasis GO:0030003 180 0.027
nucleoside catabolic process GO:0009164 126 0.027
purine nucleoside monophosphate metabolic process GO:0009126 84 0.027
response to alkaloid GO:0043279 132 0.026
organic hydroxy compound transport GO:0015850 77 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
monocarboxylic acid transport GO:0015718 52 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
aging GO:0007568 241 0.025
positive regulation of gene expression GO:0010628 244 0.025
heterocycle catabolic process GO:0046700 167 0.025
regulation of muscle system process GO:0090257 79 0.025
hormone secretion GO:0046879 115 0.025
cell growth GO:0016049 104 0.025
positive regulation of molecular function GO:0044093 230 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
cellular catabolic process GO:0044248 295 0.024
atp metabolic process GO:0046034 72 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
multicellular organism reproduction GO:0032504 233 0.023
regulation of ion transmembrane transporter activity GO:0032412 48 0.023
single organism catabolic process GO:0044712 283 0.023
purine ribonucleoside metabolic process GO:0046128 168 0.023
response to amphetamine GO:0001975 25 0.023
cellular response to ammonium ion GO:0071242 17 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
nucleoside monophosphate catabolic process GO:0009125 56 0.022
rna metabolic process GO:0016070 406 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
response to reactive oxygen species GO:0000302 120 0.022
response to ketone GO:1901654 182 0.022
multi multicellular organism process GO:0044706 138 0.022
nucleoside phosphate metabolic process GO:0006753 283 0.022
regulation of synaptic transmission GO:0050804 141 0.022
positive regulation of secretion by cell GO:1903532 128 0.022
regulation of transmembrane transporter activity GO:0022898 49 0.021
regulation of nervous system development GO:0051960 264 0.021
synaptic transmission GO:0007268 235 0.021
reproduction GO:0000003 245 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular nitrogen compound catabolic process GO:0044270 163 0.021
specification of organ identity GO:0010092 2 0.020
brain development GO:0007420 247 0.020
purine containing compound catabolic process GO:0072523 138 0.020
cellular biogenic amine metabolic process GO:0006576 30 0.020
positive regulation of peptide secretion GO:0002793 52 0.020
response to estrogen GO:0043627 232 0.019
head development GO:0060322 247 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
positive regulation of synaptic transmission gabaergic GO:0032230 9 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
nucleotide catabolic process GO:0009166 139 0.019
positive regulation of amine transport GO:0051954 26 0.019
innate immune response GO:0045087 35 0.019
lipid localization GO:0010876 62 0.019
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.019
positive regulation of cell development GO:0010720 176 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
somatostatin receptor signaling pathway GO:0038169 4 0.018
hormone transport GO:0009914 121 0.018
regulation of cell growth GO:0001558 85 0.018
ribonucleotide catabolic process GO:0009261 136 0.018
sexual reproduction GO:0019953 148 0.018
dephosphorylation GO:0016311 98 0.018
toxin transport GO:1901998 3 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
amine metabolic process GO:0009308 38 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of protein modification process GO:0031401 142 0.017
isoprenoid metabolic process GO:0006720 45 0.017
nucleoside metabolic process GO:0009116 179 0.017
purine nucleoside catabolic process GO:0006152 124 0.017
negative regulation of signaling GO:0023057 157 0.017
calcium ion transmembrane transport GO:0070588 70 0.017
organic substance catabolic process GO:1901575 316 0.017
regulation of kinase activity GO:0043549 117 0.017
regulation of ion homeostasis GO:2000021 63 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
aromatic compound catabolic process GO:0019439 168 0.017
response to nutrient levels GO:0031667 370 0.017
sequestering of metal ion GO:0051238 9 0.017
regulation of cell development GO:0060284 263 0.017
lipid biosynthetic process GO:0008610 128 0.017
atp catabolic process GO:0006200 54 0.017
regulation of neurogenesis GO:0050767 247 0.016
bmp signaling pathway GO:0030509 4 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
response to external biotic stimulus GO:0043207 221 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
cognition GO:0050890 92 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
negative regulation of innate immune response GO:0045824 4 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
regulation of muscle contraction GO:0006937 53 0.015
regulation of calcium ion transmembrane transporter activity GO:1901019 17 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
antibiotic transport GO:0042891 2 0.015
negative regulation of cell death GO:0060548 229 0.015
response to monosaccharide GO:0034284 159 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
ribonucleoside monophosphate catabolic process GO:0009158 55 0.015
peptide secretion GO:0002790 86 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
transcription dna templated GO:0006351 377 0.015
amide transport GO:0042886 105 0.015
vascular process in circulatory system GO:0003018 96 0.015
response to transforming growth factor beta GO:0071559 46 0.015
negative regulation of molecular function GO:0044092 133 0.015
organic anion transport GO:0015711 132 0.015
tube development GO:0035295 89 0.014
response to metal ion GO:0010038 253 0.014
immune response GO:0006955 104 0.014
regulation of catalytic activity GO:0050790 304 0.014
phospholipid biosynthetic process GO:0008654 29 0.014
regulation of peptide transport GO:0090087 87 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
positive regulation of developmental process GO:0051094 283 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
regulation of neuron differentiation GO:0045664 208 0.014
cardiac muscle contraction GO:0060048 27 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
ethanolamine containing compound metabolic process GO:0042439 14 0.014
protein complex subunit organization GO:0071822 302 0.014
gamete generation GO:0007276 124 0.014
regulation of calcium ion transport GO:0051924 77 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
positive regulation of response to external stimulus GO:0032103 51 0.014
male mating behavior GO:0060179 3 0.014
carbohydrate homeostasis GO:0033500 75 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
actin filament based process GO:0030029 86 0.014
regulation of cardiac muscle contraction GO:0055117 17 0.013
regulation of renin secretion into blood stream GO:1900133 1 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
lipid storage GO:0019915 1 0.013
regulation of cardiac muscle cell contraction GO:0086004 11 0.013
regulation of response to nutrient levels GO:0032107 11 0.013
organic hydroxy compound biosynthetic process GO:1901617 51 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
innate immune response activating signal transduction GO:0002758 9 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
glucan metabolic process GO:0044042 23 0.013
adult locomotory behavior GO:0008344 4 0.013
regulation of calcium ion transmembrane transport GO:1903169 18 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
cerebellar granule cell precursor proliferation GO:0021930 1 0.013
positive regulation of muscle contraction GO:0045933 22 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
cellular response to ketone GO:1901655 51 0.013
catabolic process GO:0009056 351 0.013
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.013
response to food GO:0032094 27 0.013
response to activity GO:0014823 73 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
organic acid transport GO:0015849 116 0.012
regulation of immune system process GO:0002682 123 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
macromolecule localization GO:0033036 252 0.012
programmed cell death GO:0012501 392 0.012
glycerophospholipid metabolic process GO:0006650 47 0.012
synaptic transmission gabaergic GO:0051932 22 0.012
mononuclear cell proliferation GO:0032943 29 0.012
maintenance of location GO:0051235 17 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of growth GO:0040008 105 0.012
forebrain development GO:0030900 98 0.012
sensory perception of pain GO:0019233 73 0.011
response to glucocorticoid GO:0051384 223 0.011
insulin secretion GO:0030073 69 0.011
hormone metabolic process GO:0042445 69 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
positive regulation of response to food GO:0032097 3 0.011
regulation of membrane potential GO:0042391 110 0.011
regulation of peptide secretion GO:0002791 82 0.011
cellular component assembly GO:0022607 360 0.011
positive regulation of norepinephrine secretion GO:0010701 4 0.011
catecholamine transport GO:0051937 37 0.011
cardiovascular system development GO:0072358 134 0.011
sequestering of calcium ion GO:0051208 8 0.011
response to extracellular stimulus GO:0009991 380 0.011
regulation of anion transport GO:0044070 43 0.011
positive regulation of smooth muscle contraction GO:0045987 18 0.011
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.011
neurotransmitter uptake GO:0001504 3 0.011
response to decreased oxygen levels GO:0036293 237 0.011
cytoplasmic transport GO:0016482 115 0.011
positive regulation of chemotaxis GO:0050921 23 0.011
synaptic transmission glutamatergic GO:0035249 33 0.011
single organism organelle organization GO:1902589 180 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
regulation of vascular smooth muscle contraction GO:0003056 3 0.010
phosphatidylinositol dephosphorylation GO:0046856 4 0.010
cellular response to oxidative stress GO:0034599 76 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
negative regulation of cell communication GO:0010648 158 0.010
lipid transport GO:0006869 61 0.010
ras protein signal transduction GO:0007265 29 0.010
negative regulation of gene expression GO:0010629 199 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010

Mep1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
nutrition disease DOID:374 0 0.012
acquired metabolic disease DOID:0060158 0 0.012