Rattus norvegicus

0 known processes

Tspan12

tetraspanin 12

(Aliases: Tm4sf12,MGC109305)

Tspan12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
ribonucleoside metabolic process GO:0009119 174 0.079
reproductive process GO:0022414 372 0.071
positive regulation of multicellular organismal process GO:0051240 387 0.067
catabolic process GO:0009056 351 0.065
positive regulation of response to stimulus GO:0048584 285 0.063
transcription from rna polymerase ii promoter GO:0006366 252 0.057
organic acid metabolic process GO:0006082 292 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.056
positive regulation of neurogenesis GO:0050769 165 0.056
regulation of multicellular organismal development GO:2000026 376 0.050
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.047
aging GO:0007568 241 0.046
single organism reproductive process GO:0044702 297 0.045
multi organism reproductive process GO:0044703 262 0.044
positive regulation of nervous system development GO:0051962 178 0.043
protein phosphorylation GO:0006468 345 0.042
cell type specific apoptotic process GO:0097285 134 0.040
cellular response to growth factor stimulus GO:0071363 162 0.039
negative regulation of metabolic process GO:0009892 331 0.039
regulation of cell development GO:0060284 263 0.039
tissue development GO:0009888 252 0.038
Mouse Rat
regulation of molecular function GO:0065009 398 0.037
cellular catabolic process GO:0044248 295 0.037
organophosphate metabolic process GO:0019637 370 0.037
neuron development GO:0048666 286 0.036
purine containing compound metabolic process GO:0072521 253 0.036
neuron differentiation GO:0030182 368 0.036
positive regulation of molecular function GO:0044093 230 0.035
regulation of cell differentiation GO:0045595 320 0.034
intracellular signal transduction GO:0035556 314 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
regulation of rna metabolic process GO:0051252 391 0.034
transcription dna templated GO:0006351 377 0.034
response to peptide hormone GO:0043434 278 0.033
programmed cell death GO:0012501 392 0.032
chemical homeostasis GO:0048878 292 0.032
rna metabolic process GO:0016070 406 0.032
cellular ketone metabolic process GO:0042180 51 0.032
response to inorganic substance GO:0010035 377 0.031
regulation of secretion GO:0051046 224 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
secretion GO:0046903 307 0.030
regulation of catalytic activity GO:0050790 304 0.030
nucleic acid templated transcription GO:0097659 379 0.030
neuron projection development GO:0031175 273 0.030
multicellular organism reproduction GO:0032504 233 0.030
regulation of programmed cell death GO:0043067 341 0.030
nucleotide metabolic process GO:0009117 279 0.029
reproduction GO:0000003 245 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
regulation of cellular component organization GO:0051128 368 0.029
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.029
carbohydrate derivative catabolic process GO:1901136 147 0.029
amine metabolic process GO:0009308 38 0.029
organic cyclic compound catabolic process GO:1901361 175 0.028
cell projection organization GO:0030030 302 0.028
cellular component morphogenesis GO:0032989 155 0.028
cellular response to stress GO:0033554 269 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
regulation of vasculature development GO:1901342 44 0.028
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.027
regulation of protein metabolic process GO:0051246 289 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
regulation of signal transduction GO:0009966 318 0.027
heart development GO:0007507 72 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
organonitrogen compound catabolic process GO:1901565 179 0.027
cell morphogenesis GO:0000902 142 0.027
single organism organelle organization GO:1902589 180 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
regulation of nervous system development GO:0051960 264 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
regulation of secretion by cell GO:1903530 208 0.026
rna biosynthetic process GO:0032774 380 0.025
lipid metabolic process GO:0006629 283 0.025
response to growth factor GO:0070848 189 0.025
regulation of cellular catabolic process GO:0031329 101 0.025
regulation of apoptotic process GO:0042981 335 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
cardiovascular system development GO:0072358 134 0.025
Mouse
anion transport GO:0006820 178 0.024
positive regulation of signal transduction GO:0009967 175 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
regulation of purine nucleotide metabolic process GO:1900542 115 0.024
cation homeostasis GO:0055080 195 0.024
regulation of gtpase activity GO:0043087 57 0.024
negative regulation of transport GO:0051051 136 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
positive regulation of developmental process GO:0051094 283 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
response to nutrient levels GO:0031667 370 0.023
response to extracellular stimulus GO:0009991 380 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
regulation of nucleotide metabolic process GO:0006140 117 0.023
nucleoside metabolic process GO:0009116 179 0.023
regulation of cell proliferation GO:0042127 359 0.023
positive regulation of neuron differentiation GO:0045666 126 0.023
cell cell signaling GO:0007267 335 0.023
regulation of neuron projection development GO:0010975 161 0.023
cell migration GO:0016477 197 0.023
Rat
cellular amine metabolic process GO:0044106 38 0.022
homeostatic process GO:0042592 331 0.022
ovulation cycle process GO:0022602 50 0.022
embryonic pattern specification GO:0009880 1 0.022
ion homeostasis GO:0050801 212 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
regulation of hydrolase activity GO:0051336 143 0.021
single organism biosynthetic process GO:0044711 342 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
synaptic transmission GO:0007268 235 0.021
purine containing compound catabolic process GO:0072523 138 0.020
cellular homeostasis GO:0019725 252 0.020
guanosine containing compound catabolic process GO:1901069 71 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
apoptotic process GO:0006915 381 0.020
negative regulation of developmental process GO:0051093 125 0.020
positive regulation of cell development GO:0010720 176 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
Mouse
negative regulation of programmed cell death GO:0043069 183 0.020
regulation of protein modification process GO:0031399 194 0.020
regulation of neurogenesis GO:0050767 247 0.020
positive regulation of rap gtpase activity GO:0032854 4 0.020
gamete generation GO:0007276 124 0.020
aromatic compound catabolic process GO:0019439 168 0.020
nucleotide catabolic process GO:0009166 139 0.020
positive regulation of immune system process GO:0002684 90 0.020
ribose phosphate metabolic process GO:0019693 235 0.019
macromolecule localization GO:0033036 252 0.019
sexual reproduction GO:0019953 148 0.019
secretion by cell GO:0032940 248 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
carboxylic acid transport GO:0046942 115 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
positive regulation of biosynthetic process GO:0009891 319 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
oxoacid metabolic process GO:0043436 290 0.018
transmembrane transport GO:0055085 412 0.018
positive regulation of cell death GO:0010942 184 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
gonad development GO:0008406 104 0.018
vasculature development GO:0001944 70 0.018
Mouse
guanosine containing compound metabolic process GO:1901068 74 0.018
anterior posterior pattern specification GO:0009952 1 0.018
negative regulation of secretion GO:0051048 82 0.018
ovulation cycle GO:0042698 67 0.018
protein complex biogenesis GO:0070271 263 0.018
single organism catabolic process GO:0044712 283 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
gland development GO:0048732 155 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
Rat
organophosphate catabolic process GO:0046434 148 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
response to nutrient GO:0007584 248 0.017
cellular component biogenesis GO:0044085 368 0.016
negative regulation of cardiac muscle tissue development GO:0055026 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
response to external biotic stimulus GO:0043207 221 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
regulation of purine nucleotide catabolic process GO:0033121 65 0.016
positive regulation of cell communication GO:0010647 271 0.016
response to organophosphorus GO:0046683 102 0.016
purine nucleoside catabolic process GO:0006152 124 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
female pregnancy GO:0007565 122 0.015
cellular macromolecule localization GO:0070727 122 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
positive regulation of gtp catabolic process GO:0033126 48 0.015
cellular component movement GO:0006928 248 0.015
Rat
immune system process GO:0002376 204 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
organic anion transport GO:0015711 132 0.015
cellular ion homeostasis GO:0006873 184 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
cell part morphogenesis GO:0032990 123 0.015
small molecule biosynthetic process GO:0044283 124 0.015
negative regulation of cell death GO:0060548 229 0.015
dephosphorylation GO:0016311 98 0.015
protein complex subunit organization GO:0071822 302 0.015
purine nucleotide metabolic process GO:0006163 229 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
metal ion homeostasis GO:0055065 186 0.014
regulation of ras gtpase activity GO:0032318 32 0.014
cellular cation homeostasis GO:0030003 180 0.014
cell projection morphogenesis GO:0048858 123 0.014
regulation of embryonic development GO:0045995 2 0.014
intracellular protein transport GO:0006886 79 0.014
embryonic axis specification GO:0000578 1 0.014
axon development GO:0061564 96 0.014
growth GO:0040007 165 0.014
organic substance catabolic process GO:1901575 316 0.014
circulatory system process GO:0003013 183 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
positive regulation of signaling GO:0023056 270 0.014
cell growth GO:0016049 104 0.014
calcium ion homeostasis GO:0055074 162 0.014
response to corticosteroid GO:0031960 235 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
defense response GO:0006952 194 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
negative regulation of molecular function GO:0044092 133 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
response to oxidative stress GO:0006979 186 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
negative regulation of cell communication GO:0010648 158 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
cellular chemical homeostasis GO:0055082 247 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
regulation of cell projection organization GO:0031344 175 0.013
regulation of neuron differentiation GO:0045664 208 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
axis specification GO:0009798 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 55 0.013
rhythmic process GO:0048511 156 0.013
response to other organism GO:0051707 220 0.013
ras protein signal transduction GO:0007265 29 0.013
positive regulation of programmed cell death GO:0043068 157 0.012
circulatory system development GO:0072359 134 0.012
Mouse
single organism intracellular transport GO:1902582 166 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
positive regulation of catabolic process GO:0009896 78 0.012
organelle organization GO:0006996 266 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
regulation of transcription dna templated GO:0006355 374 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
fertilization GO:0009566 3 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
response to decreased oxygen levels GO:0036293 237 0.012
small molecule catabolic process GO:0044282 59 0.012
response to wounding GO:0009611 254 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
signal release GO:0023061 145 0.012
regeneration GO:0031099 163 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
organic hydroxy compound transport GO:0015850 77 0.012
locomotion GO:0040011 237 0.012
Rat
protein localization GO:0008104 191 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
head development GO:0060322 247 0.012
response to estrogen GO:0043627 232 0.012
heterocycle catabolic process GO:0046700 167 0.012
response to glucose GO:0009749 136 0.012
positive regulation of gtpase activity GO:0043547 47 0.012
regulation of gtp catabolic process GO:0033124 58 0.012
regulation of cellular localization GO:0060341 263 0.011
protein complex assembly GO:0006461 263 0.011
regulation of phosphorylation GO:0042325 248 0.011
vascular process in circulatory system GO:0003018 96 0.011
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.011
response to peptide GO:1901652 292 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
response to lipopolysaccharide GO:0032496 191 0.011
immune effector process GO:0002252 53 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
neuron projection morphogenesis GO:0048812 122 0.011
cellular component assembly GO:0022607 360 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
reproductive system development GO:0061458 128 0.011
sterol homeostasis GO:0055092 3 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
negative regulation of gene expression GO:0010629 199 0.011
ion transmembrane transport GO:0034220 365 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
gtp catabolic process GO:0006184 71 0.011
regulation of ion transport GO:0043269 245 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
actin filament based process GO:0030029 86 0.011
positive regulation of gene expression GO:0010628 244 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
development of primary sexual characteristics GO:0045137 107 0.011
metal ion transport GO:0030001 289 0.011
regulation of mapk cascade GO:0043408 116 0.011
cellular lipid metabolic process GO:0044255 208 0.011
cation transmembrane transport GO:0098655 263 0.011
regulation of rap gtpase activity GO:0032317 4 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of catabolic process GO:0009894 113 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
regulation of response to external stimulus GO:0032101 106 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
Mouse
negative regulation of heart growth GO:0061117 3 0.011
substrate dependent cell migration GO:0006929 1 0.011
multi multicellular organism process GO:0044706 138 0.010
gtp metabolic process GO:0046039 72 0.010
regulation of blood circulation GO:1903522 110 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
response to insulin GO:0032868 133 0.010
positive regulation of cell migration GO:0030335 96 0.010
response to ammonium ion GO:0060359 71 0.010
heart morphogenesis GO:0003007 3 0.010
regulation of synaptic transmission GO:0050804 141 0.010
negative regulation of organ growth GO:0046621 3 0.010
central nervous system development GO:0007417 311 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
positive regulation of locomotion GO:0040017 102 0.010
nucleoside catabolic process GO:0009164 126 0.010
cation transport GO:0006812 382 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
positive regulation of protein modification process GO:0031401 142 0.010

Tspan12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
Human
nervous system disease DOID:863 0 0.022
Human
disease of metabolism DOID:0014667 0 0.015